DE60029876D1 - Verfahren und Oligonukleotide zum Nachweis von Nukleinsäuresequenzvariationen - Google Patents
Verfahren und Oligonukleotide zum Nachweis von NukleinsäuresequenzvariationenInfo
- Publication number
- DE60029876D1 DE60029876D1 DE60029876T DE60029876T DE60029876D1 DE 60029876 D1 DE60029876 D1 DE 60029876D1 DE 60029876 T DE60029876 T DE 60029876T DE 60029876 T DE60029876 T DE 60029876T DE 60029876 D1 DE60029876 D1 DE 60029876D1
- Authority
- DE
- Germany
- Prior art keywords
- oligonucleotides
- methods
- nucleic acid
- acid sequence
- sequence variations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/335,218 US20020025519A1 (en) | 1999-06-17 | 1999-06-17 | Methods and oligonucleotides for detecting nucleic acid sequence variations |
| US335218 | 2002-12-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60029876D1 true DE60029876D1 (de) | 2006-09-21 |
| DE60029876T2 DE60029876T2 (de) | 2007-02-01 |
Family
ID=23310785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60029876T Expired - Lifetime DE60029876T2 (de) | 1999-06-17 | 2000-04-17 | Verfahren und Oligonukleotide zum Nachweis von Nukleinsäuresequenzvariationen |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US20020025519A1 (de) |
| EP (1) | EP1061135B1 (de) |
| JP (2) | JP2001057892A (de) |
| AU (1) | AU781136B2 (de) |
| CA (1) | CA2306055A1 (de) |
| DE (1) | DE60029876T2 (de) |
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| EP3931351B1 (de) * | 2019-03-01 | 2024-09-11 | Mercy Bioanalytics, Inc. | Ligase verwendendes verfahren zur detektion von targetmoleküle |
| CN113308519B (zh) * | 2021-06-30 | 2022-06-07 | 上海伯杰医疗科技股份有限公司北京分公司 | 用于检测单碱基突变位点的引物和探针及检测方法 |
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-
1999
- 1999-06-17 US US09/335,218 patent/US20020025519A1/en not_active Abandoned
-
2000
- 2000-04-17 DE DE60029876T patent/DE60029876T2/de not_active Expired - Lifetime
- 2000-04-17 EP EP00108366A patent/EP1061135B1/de not_active Expired - Lifetime
- 2000-04-19 CA CA002306055A patent/CA2306055A1/en not_active Abandoned
- 2000-06-14 AU AU40852/00A patent/AU781136B2/en not_active Ceased
- 2000-06-19 JP JP2000182884A patent/JP2001057892A/ja not_active Withdrawn
-
2001
- 2001-02-07 US US09/778,175 patent/US20010039334A1/en not_active Abandoned
- 2001-02-07 US US09/778,168 patent/US7223536B2/en not_active Expired - Fee Related
-
2007
- 2007-03-15 US US11/724,180 patent/US20090131647A1/en not_active Abandoned
-
2008
- 2008-05-02 JP JP2008120646A patent/JP2008200050A/ja active Pending
-
2009
- 2009-04-07 US US12/419,737 patent/US8323929B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2306055A1 (en) | 2000-12-17 |
| AU781136B2 (en) | 2005-05-05 |
| DE60029876T2 (de) | 2007-02-01 |
| AU4085200A (en) | 2000-12-21 |
| US7223536B2 (en) | 2007-05-29 |
| US20010039334A1 (en) | 2001-11-08 |
| US20090131647A1 (en) | 2009-05-21 |
| US8323929B2 (en) | 2012-12-04 |
| JP2001057892A (ja) | 2001-03-06 |
| JP2008200050A (ja) | 2008-09-04 |
| EP1061135A2 (de) | 2000-12-20 |
| EP1061135B1 (de) | 2006-08-09 |
| EP1061135A3 (de) | 2003-06-25 |
| US20090246792A1 (en) | 2009-10-01 |
| US20010009761A1 (en) | 2001-07-26 |
| US20020025519A1 (en) | 2002-02-28 |
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| 8364 | No opposition during term of opposition |