DE60025958D1 - 14,15-BETA-METHYLENE SUBSTITUTED ANDROGENE - Google Patents

14,15-BETA-METHYLENE SUBSTITUTED ANDROGENE

Info

Publication number: DE60025958D1
Authority: DE; Germany
Prior art keywords: androgene; beta; methylene substituted; methylene; substituted
Prior art date: 1999-12-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60025958T

Other languages

German (de)

Other versions

DE60025958T2 (en

Inventor

Dirk Leysen

Der Louw Jaap Van

Bursi Roberta Buma

Gooyer Evert De

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Organon NV

Original Assignee

Akzo Nobel NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-02

Filing date

2000-11-29

Publication date

2006-04-20

2000-11-29 Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV

2006-04-20 Publication of DE60025958D1 publication Critical patent/DE60025958D1/en

2006-07-27 Application granted granted Critical

2006-07-27 Publication of DE60025958T2 publication Critical patent/DE60025958T2/en

2020-11-30 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Endocrinology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Fodder In General (AREA)

DE60025958T 1999-12-02 2000-11-29 14,15-BETA-METHYLENE SUBSTITUTED ANDROGENE Expired - Lifetime DE60025958T2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP99204080		1999-12-02
EP99204080		1999-12-02
PCT/EP2000/012009 WO2001040255A2 (en)	1999-12-02	2000-11-29	14,15-beta-methylene substituted androgens

Publications (2)

Publication Number	Publication Date
DE60025958D1 true DE60025958D1 (en)	2006-04-20
DE60025958T2 DE60025958T2 (en)	2006-07-27

Family

ID=8240955

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60025958T Expired - Lifetime DE60025958T2 (en)	1999-12-02	2000-11-29	14,15-BETA-METHYLENE SUBSTITUTED ANDROGENE

Country Status (27)

Country	Link
US (1)	US6706700B2 (en)
EP (1)	EP1237904B1 (en)
JP (1)	JP2003515543A (en)
CN (1)	CN1166680C (en)
AR (1)	AR026655A1 (en)
AT (1)	ATE317396T1 (en)
AU (1)	AU778017B2 (en)
CA (1)	CA2390226A1 (en)
CO (1)	CO5251441A1 (en)
CY (1)	CY1106086T1 (en)
CZ (1)	CZ301376B6 (en)
DE (1)	DE60025958T2 (en)
DK (1)	DK1237904T3 (en)
ES (1)	ES2258037T3 (en)
HK (1)	HK1047596B (en)
HU (1)	HUP0203611A3 (en)
IL (1)	IL149424A (en)
MX (1)	MXPA02004939A (en)
NO (1)	NO322422B1 (en)
NZ (1)	NZ518753A (en)
PE (1)	PE20011033A1 (en)
PL (1)	PL202999B1 (en)
RU (1)	RU2242479C2 (en)
SK (1)	SK287095B6 (en)
TW (1)	TWI275593B (en)
WO (1)	WO2001040255A2 (en)
ZA (1)	ZA200203536B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60004377T2 (en) *	1999-04-06	2004-06-09	Akzo Nobel N.V.	ORAL EFFECTIVE 7-ALPHA-ALKYL ANDROGENE
MXPA04007049A (en) *	2002-01-21	2004-10-14	Akzo Nobel Nv	PROCESS FOR THE PREPARATION OF 7alpha-METHYLSTEROIDS.
US20080293683A1 (en) *	2007-05-24	2008-11-27	University Of Kansas Medical Center	Hormone Replacement Therapy
EP2383279A1 (en)	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol
KR102007874B1 (en) *	2011-10-07	2019-08-06	에스테트라 에스.피.알.엘.	Process for the production of estetrol
UA123098C2 (en)	2015-06-18	2021-02-17	Естетра Спрл	DISPOSABLE UNIT OF DOSAGE CONTAINING AN ESTETRAL COMPONENT DISPERSED IN THE ORAL CAVITY
PE20180522A1 (en)	2015-06-18	2018-03-14	Mithra Pharmaceuticals S A	ORODISPERSABLE DOSING UNIT CONTAINING A STETROL COMPONENT
CA2988485A1 (en)	2015-06-18	2016-12-22	Mithra Pharmaceuticals S.A.	Orodispersible tablet containing estetrol
EP3310346B1 (en)	2015-06-18	2021-03-24	Estetra SPRL	Orodispersible tablet containing estetrol
KR102712911B1 (en)	2016-08-05	2024-10-04	에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼	Method for the management of dysmenorrhea and menstrual pain
TWI801561B (en)	2018-04-19	2023-05-11	比利時商依思特拉私人有限責任公司	Compounds and their uses for alleviating menopause-associated symptoms
JOP20200260A1 (en)	2018-04-19	2019-10-19	Estetra Sprl	Compounds and their uses for alleviating menopause-associated symptoms
TWI893101B (en)	2020-04-16	2025-08-11	比利時商埃斯特拉有限責任公司	Contraceptive compositions with reduced adverse effects
CN111621141B (en) *	2020-06-12	2022-04-08	广西大学	A slow-release chlorine dioxide-water-based polyurethane antibacterial film and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3086027A (en) *	1960-01-22	1963-04-16	Lilly Co Eli	19-nor-4, 9(10)-steroids and process
IE60780B1 (en) *	1987-01-23	1994-08-10	Akzo Nv	New 11-aryl steroid derivatives
DE19537626A1 (en) *	1995-10-10	1997-04-17	Jenapharm Gmbh	Steroids with a 14, 15 methylene group
DE19827522A1 (en) *	1998-06-22	1999-12-23	Jenapharm Gmbh	New derivatives of 19-norandrostane useful in fertility control or treatment of e.g. endometriosis, mammary carcinoma or hypogonadism
EP1163259B1 (en) *	1999-03-08	2002-11-20	Akzo Nobel N.V.	14.beta.,17-alpha-hydroxymethylandrostane derivatives as androgens

2000
- 2000-11-29 IL IL149424A patent/IL149424A/en not_active IP Right Cessation
- 2000-11-29 PL PL355689A patent/PL202999B1/en not_active IP Right Cessation
- 2000-11-29 JP JP2001541010A patent/JP2003515543A/en active Pending
- 2000-11-29 ES ES00993259T patent/ES2258037T3/en not_active Expired - Lifetime
- 2000-11-29 CN CNB008164959A patent/CN1166680C/en not_active Expired - Fee Related
- 2000-11-29 EP EP00993259A patent/EP1237904B1/en not_active Expired - Lifetime
- 2000-11-29 AT AT00993259T patent/ATE317396T1/en not_active IP Right Cessation
- 2000-11-29 US US10/148,820 patent/US6706700B2/en not_active Expired - Fee Related
- 2000-11-29 CZ CZ20021894A patent/CZ301376B6/en not_active IP Right Cessation
- 2000-11-29 DE DE60025958T patent/DE60025958T2/en not_active Expired - Lifetime
- 2000-11-29 CA CA002390226A patent/CA2390226A1/en not_active Abandoned
- 2000-11-29 HK HK02109169.4A patent/HK1047596B/en not_active IP Right Cessation
- 2000-11-29 SK SK758-2002A patent/SK287095B6/en not_active IP Right Cessation
- 2000-11-29 NZ NZ518753A patent/NZ518753A/en unknown
- 2000-11-29 DK DK00993259T patent/DK1237904T3/en active
- 2000-11-29 RU RU2002117440/04A patent/RU2242479C2/en not_active IP Right Cessation
- 2000-11-29 AU AU28383/01A patent/AU778017B2/en not_active Ceased
- 2000-11-29 MX MXPA02004939A patent/MXPA02004939A/en active IP Right Grant
- 2000-11-29 WO PCT/EP2000/012009 patent/WO2001040255A2/en not_active Ceased
- 2000-11-29 HU HU0203611A patent/HUP0203611A3/en unknown
- 2000-11-30 AR ARP000106304A patent/AR026655A1/en active IP Right Grant
- 2000-12-01 CO CO00092012A patent/CO5251441A1/en not_active Application Discontinuation
- 2000-12-01 PE PE2000001285A patent/PE20011033A1/en not_active Application Discontinuation
- 2000-12-02 TW TW089125707A patent/TWI275593B/en not_active IP Right Cessation
2002
- 2002-05-03 ZA ZA200203536A patent/ZA200203536B/en unknown
- 2002-05-30 NO NO20022564A patent/NO322422B1/en not_active IP Right Cessation
2006
- 2006-04-10 CY CY20061100500T patent/CY1106086T1/en unknown

Also Published As

Publication number	Publication date
CN1166680C (en)	2004-09-15
EP1237904A2 (en)	2002-09-11
TWI275593B (en)	2007-03-11
RU2242479C2 (en)	2004-12-20
SK287095B6 (en)	2009-12-07
WO2001040255A3 (en)	2001-11-15
HUP0203611A2 (en)	2003-03-28
HK1047596A1 (en)	2003-02-28
CO5251441A1 (en)	2003-02-28
JP2003515543A (en)	2003-05-07
US20030100543A1 (en)	2003-05-29
IL149424A (en)	2007-05-15
IL149424A0 (en)	2002-11-10
PL355689A1 (en)	2004-05-17
ES2258037T3 (en)	2006-08-16
EP1237904B1 (en)	2006-02-08
CN1402735A (en)	2003-03-12
NZ518753A (en)	2004-05-28
AR026655A1 (en)	2003-02-19
CA2390226A1 (en)	2001-06-07
NO322422B1 (en)	2006-10-02
MXPA02004939A (en)	2003-05-23
DK1237904T3 (en)	2006-06-06
ZA200203536B (en)	2003-08-04
WO2001040255A2 (en)	2001-06-07
CZ20021894A3 (en)	2002-08-14
DE60025958T2 (en)	2006-07-27
NO20022564D0 (en)	2002-05-30
SK7582002A3 (en)	2002-09-10
PE20011033A1 (en)	2001-10-11
NO20022564L (en)	2002-05-30
AU2838301A (en)	2001-06-12
HK1047596B (en)	2006-04-21
CY1106086T1 (en)	2011-06-08
AU778017B2 (en)	2004-11-11
PL202999B1 (en)	2009-08-31
HUP0203611A3 (en)	2004-07-28
CZ301376B6 (en)	2010-02-03
US6706700B2 (en)	2004-03-16
ATE317396T1 (en)	2006-02-15

Publication	Publication Date	Title
ID29241A (en)	2001-08-16	TERANELASI KINOLIN DISTRICTS-1,2
DE69933287D1 (en)	2006-11-02	12,13-MODIFIED EPOTHILON DERIVATIVES
MA25499A1 (en)	2002-07-01	CONTACTOR-CIRCUIT-BREAKER.
MA26849A1 (en)	2004-12-20	4-pyridinyl-N-ACYL-L-phenylalanine.
ID28483A (en)	2001-05-31	2- (3,5-BIS-TRIFLUOROMETYL-PHENIL) -METIL-N- (6-MORFOLIN-4-IL-4-0-TOLYL-PYRIDIN-3-IL) -ISOBUTIRAMIDA
PT1210349E (en)	2003-06-30	PYRAZOLO-¬4,3-D \| -PYRIMIDINES
DE50107988D1 (en)	2005-12-15	SUBSTITUTED 1,2,3,4-TETRAHYDROCHINOLIN-2-CARBOXYLENE DERIVATIVES
DE60025958D1 (en)	2006-04-20	14,15-BETA-METHYLENE SUBSTITUTED ANDROGENE
NO20003825L (en)	2000-07-26	1,3,4 - oxadiazolone derivatives
ITBO990359A0 (en)	1999-06-30	ELECTROSPINDLE.
DE60029755D1 (en)	2006-09-14	CONGAWANDSCHUTZ.
ATE234839T1 (en)	2003-04-15	4,5-AZOLO-OXINDOLES
EP1192168A4 (en)	2003-04-16	GALECTINE 11
ITBO990358A0 (en)	1999-06-30	ELECTROSPINDLE.
ID26368A (en)	2000-12-14	DECREASED 2, HYDROMICIN DEXY
ES1042496Y (en)	2000-02-01	"PILONA SUBIBLE".
ES1044367Y (en)	2000-09-01	IMPROVED PIÑATA.
ES1044838Y (en)	2000-11-16	FRIEGASUELOS.
ITSS990004V0 (en)	1999-06-08	PYRAMID - REMEMBER.
ITCS990004V0 (en)	1999-08-09	"TERMOCAMIN0 C.C.M."
DE60017150D1 (en)	2005-02-03	1,4,5,6-Tetra-Hydropropylidene-Derivatives as VITRONECTIN-INHIBITORS
ES1044013Y (en)	2000-09-16	NEW IMPROVED CANTONERA.
IT1313922B1 (en)	2002-09-26	IMPROVED ELECTROSPINDLE.
ES1042809Y (en)	2000-03-16	IMPROVED SPONGE-SCRAP.
IT247637Y1 (en)	2002-09-09	Tritapepe.

Legal Events

Date	Code	Title	Description
2007-03-08	8364	No opposition during term of opposition
2007-06-14	8327	Change in the person/name/address of the patent owner	Owner name: N.V. ORGANON, OSS, NL