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DE60006811D1 - Apparat zum betrieb eines mikrofluidischen gerätes - Google Patents

Apparat zum betrieb eines mikrofluidischen gerätes

Info

Publication number
DE60006811D1
DE60006811D1 DE60006811T DE60006811T DE60006811D1 DE 60006811 D1 DE60006811 D1 DE 60006811D1 DE 60006811 T DE60006811 T DE 60006811T DE 60006811 T DE60006811 T DE 60006811T DE 60006811 D1 DE60006811 D1 DE 60006811D1
Authority
DE
Germany
Prior art keywords
microchip
physical unit
supply systems
ease
operating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60006811T
Other languages
English (en)
Other versions
DE60006811T2 (de
Inventor
Manfred Berndt
Patrick Kaltenbach
B Kennedy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Caliper Life Sciences Inc
Agilent Technologies Inc
Original Assignee
Agilent Technologies Inc
Caliper Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Inc, Caliper Technologies Corp filed Critical Agilent Technologies Inc
Publication of DE60006811D1 publication Critical patent/DE60006811D1/de
Application granted granted Critical
Publication of DE60006811T2 publication Critical patent/DE60006811T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56Labware specially adapted for transferring fluids
    • B01L3/565Seals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00237Handling microquantities of analyte, e.g. microvalves, capillary networks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
DE60006811T 1999-06-22 2000-06-15 Apparat zum betrieb eines mikrofluidischen gerätes Expired - Lifetime DE60006811T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14021599P 1999-06-22 1999-06-22
US140215P 1999-06-22
PCT/US2000/016790 WO2000078454A1 (en) 1999-06-22 2000-06-15 Apparatus for the operation of a microfluidic device

Publications (2)

Publication Number Publication Date
DE60006811D1 true DE60006811D1 (de) 2004-01-08
DE60006811T2 DE60006811T2 (de) 2005-08-04

Family

ID=22490242

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006811T Expired - Lifetime DE60006811T2 (de) 1999-06-22 2000-06-15 Apparat zum betrieb eines mikrofluidischen gerätes

Country Status (6)

Country Link
EP (1) EP1187677B1 (de)
JP (1) JP2003502655A (de)
AT (1) ATE254963T1 (de)
AU (1) AU5877600A (de)
DE (1) DE60006811T2 (de)
WO (1) WO2000078454A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759013B2 (en) 1998-09-17 2004-07-06 Agilent Technologies, Inc. Modular apparatus for chemical microanalysis
US6811668B1 (en) 1999-06-22 2004-11-02 Caliper Life Sciences, Inc. Apparatus for the operation of a microfluidic device
US6358387B1 (en) * 2000-03-27 2002-03-19 Caliper Technologies Corporation Ultra high throughput microfluidic analytical systems and methods
AU2001259770A1 (en) 2000-05-15 2001-11-26 Biomicro Systems, Inc. Air flow regulation in microfluidic circuits for pressure control and gaseous exchange
US6615856B2 (en) 2000-08-04 2003-09-09 Biomicro Systems, Inc. Remote valving for microfluidic flow control
US6827095B2 (en) 2000-10-12 2004-12-07 Nanostream, Inc. Modular microfluidic systems
US20090118139A1 (en) 2000-11-07 2009-05-07 Caliper Life Sciences, Inc. Microfluidic method and system for enzyme inhibition activity screening
DE10209897A1 (de) * 2002-03-08 2003-09-25 Merck Patent Gmbh Mikrokomponenten-Anschlusssystem
AU2002318070A1 (en) * 2002-07-26 2004-02-16 Avantium International B.V. System for performing a chemical reaction on a plurality of different microreactors
NZ620811A (en) 2005-05-09 2015-09-25 Theranos Inc Point-of-care fluidic systems and uses thereof
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
DE102006057300A1 (de) * 2006-12-05 2008-06-19 Siemens Ag Anordnung zur Aufbereitung einer Mehrzahl von Proben für eine Analyse
EP2104568A1 (de) 2007-01-17 2009-09-30 Agilent Technologies, Inc. Mikrofluidik-chip mit seitlicher öffnung zur einleitung von fluid
DE102007018752B4 (de) * 2007-04-20 2011-09-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung und Verfahren zum geregelten Transport mikrofluidischer Proben
EP2167233B1 (de) 2007-06-26 2013-01-23 Micronit Microfluidics B.V. Vorrichtung und verfahren zur strömungskopplung von fluidleitungen mit einem mikrofluidchip und zum entkoppeln davon
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
MX352987B (es) 2007-10-02 2017-12-15 Theranos Ip Co Llc Dispositivos modulares de punto de cuidado y usos de los mismos.
DE602007007927D1 (de) 2007-11-05 2010-09-02 Agilent Technologies Inc Einfrierung eines mikrofluidischen Chips
EP4047367A1 (de) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
US20100213063A1 (en) 2009-02-09 2010-08-26 Frederic Zenhausern Analysis
MY165876A (en) 2009-10-19 2018-05-18 Theranos Inc Integrated health data capture and analysis system
JP5934657B2 (ja) 2010-02-12 2016-06-15 レインダンス テクノロジーズ, インコーポレイテッド デジタル検体分析
GB201010737D0 (en) 2010-06-25 2010-08-11 Imp Innovations Ltd Minature HPLC device
CA2825196C (en) 2011-01-21 2021-01-05 Theranos, Inc. Systems and methods for sample use maximization
TWI489110B (zh) 2011-11-02 2015-06-21 Wistron Corp 生物晶片
EP4206681A1 (de) * 2015-04-02 2023-07-05 Cepheid Fluidische brückenvorrichtung und probenverarbeitungsverfahren
WO2018002693A1 (en) * 2016-07-01 2018-01-04 Tubitak Mobile hand-held device with reusable biosensor cartridge
JP7366754B2 (ja) * 2017-02-07 2023-10-23 ノデクサス インコーポレーテッド 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法
GB2598113B (en) 2020-08-18 2024-11-20 Agilent Technologies Inc Fluidically coupling with elastic structure deformable by sealing element
US12442791B2 (en) * 2022-07-05 2025-10-14 Arkray, Inc. Analysis system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US6399023B1 (en) * 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
US5989402A (en) * 1997-08-29 1999-11-23 Caliper Technologies Corp. Controller/detector interfaces for microfluidic systems
US6041515A (en) * 1998-01-12 2000-03-28 Life Technologies, Inc. Apparatus for drying solutions containing macromolecules

Also Published As

Publication number Publication date
AU5877600A (en) 2001-01-09
EP1187677B1 (de) 2003-11-26
WO2000078454A1 (en) 2000-12-28
JP2003502655A (ja) 2003-01-21
ATE254963T1 (de) 2003-12-15
DE60006811T2 (de) 2005-08-04
EP1187677A1 (de) 2002-03-20

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: CALIPER LIFE SCIENCES (N.D.GES.D.STAATES DELAWARE)

Owner name: AGILENT TECHNOLOGIES, INC. (N.D.GES.D.STAATES DELA

8364 No opposition during term of opposition