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DE4092406A1 - - Google Patents

Info

Publication number
DE4092406A1
DE4092406A1 DE19904092406 DE4092406A DE4092406A1 DE 4092406 A1 DE4092406 A1 DE 4092406A1 DE 19904092406 DE19904092406 DE 19904092406 DE 4092406 A DE4092406 A DE 4092406A DE 4092406 A1 DE4092406 A1 DE 4092406A1
Authority
DE
Germany
Prior art keywords
substituents
symbols
formula
pharmacological properties
interesting pharmacological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19904092406
Other languages
German (de)
Other versions
DE4092406D2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DE4092406A1 publication Critical patent/DE4092406A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Described are new dihydropyridines, which have interesting pharmacological properties, of the formula (I): in which the substituents and other symbols are as defined in the specification.
DE19904092406 1989-12-22 1990-12-19 Withdrawn DE4092406A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH462589 1989-12-22

Publications (1)

Publication Number Publication Date
DE4092406A1 true DE4092406A1 (en) 1993-04-01

Family

ID=4279620

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19904092406 Withdrawn DE4092406A1 (en) 1989-12-22 1990-12-19
DE90EP9002236D Expired - Lifetime DE4092406D2 (en) 1989-12-22 1990-12-19 Neue dihydropyridine

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE90EP9002236D Expired - Lifetime DE4092406D2 (en) 1989-12-22 1990-12-19 Neue dihydropyridine

Country Status (5)

Country Link
EP (1) EP0506801A1 (en)
JP (1) JPH05504345A (en)
AU (1) AU7058991A (en)
DE (2) DE4092406A1 (en)
WO (1) WO1991009846A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0511790A1 (en) * 1991-04-26 1992-11-04 Ajinomoto Co., Inc. 1,4-Dihydropyridine derivatives useful against tumour cells
US5767131A (en) * 1993-04-05 1998-06-16 Synaptic Pharmaceutical Corporation Dihydropyridines and new uses thereof
IL109220A0 (en) * 1993-04-05 1994-07-31 Synaptic Pharma Corp Dihydropyridines and new uses thereof
US6211198B1 (en) 1993-04-05 2001-04-03 Synaptic Pharmaceutical Corporation Dihydropyridines and new uses thereof
US6376514B1 (en) 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603135A (en) * 1983-10-17 1986-07-29 Takeda Chemical Industries, Ltd. Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates
JPS61227567A (en) * 1985-04-01 1986-10-09 Eisai Co Ltd 1,4-dihydropyridine derivative
FR2596760B1 (en) * 1986-04-02 1988-12-09 Sori Soc Rech Ind DISSYMMETRIC DERIVATIVES OF 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID, METHODS OF PREPARATION AND THERAPEUTIC USE
NZ220022A (en) * 1986-04-22 1990-04-26 Byk Gulden Lomberg Chem Fab 1,4-dihydropyridine derivatives and pharmaceutical compositions
AU2614288A (en) * 1987-10-27 1989-05-23 Byk Gulden Lomberg Chemische Fabrik Gmbh New pyrrolidines

Also Published As

Publication number Publication date
WO1991009846A1 (en) 1991-07-11
DE4092406D2 (en) 1993-04-01
JPH05504345A (en) 1993-07-08
AU7058991A (en) 1991-07-24
EP0506801A1 (en) 1992-10-07

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee