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DE3853535D1 - Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung. - Google Patents

Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.

Info

Publication number
DE3853535D1
DE3853535D1 DE3853535T DE3853535T DE3853535D1 DE 3853535 D1 DE3853535 D1 DE 3853535D1 DE 3853535 T DE3853535 T DE 3853535T DE 3853535 T DE3853535 T DE 3853535T DE 3853535 D1 DE3853535 D1 DE 3853535D1
Authority
DE
Germany
Prior art keywords
phage
antimicrobial agents
cells
protein
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3853535T
Other languages
English (en)
Other versions
DE3853535T2 (de
Inventor
Jesse Jaynes
Frederick M Enright
Kenneth White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helix Biomedix Inc
Original Assignee
Louisiana State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Louisiana State University filed Critical Louisiana State University
Application granted granted Critical
Publication of DE3853535D1 publication Critical patent/DE3853535D1/de
Publication of DE3853535T2 publication Critical patent/DE3853535T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Insects & Arthropods (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE3853535T 1987-07-06 1988-07-06 Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung. Expired - Lifetime DE3853535T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6965387A 1987-07-06 1987-07-06
PCT/US1988/002265 WO1989000199A1 (en) 1987-07-06 1988-07-06 Therapeutic antimicrobial polypeptides, their use and methods for preparation

Publications (2)

Publication Number Publication Date
DE3853535D1 true DE3853535D1 (de) 1995-05-11
DE3853535T2 DE3853535T2 (de) 1995-10-12

Family

ID=22090376

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853535T Expired - Lifetime DE3853535T2 (de) 1987-07-06 1988-07-06 Ärztliche antimikrobielle polypeptide, deren verwendung und verfahren zur herstellung.

Country Status (8)

Country Link
US (1) US6303568B1 (de)
EP (1) EP0365598B1 (de)
KR (1) KR970005048B1 (de)
AT (1) ATE120795T1 (de)
AU (1) AU2071488A (de)
CA (1) CA1327311C (de)
DE (1) DE3853535T2 (de)
WO (1) WO1989000199A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110754400A (zh) * 2019-10-28 2020-02-07 长江大学 一种提高黄鳝苗种人工孵化率的方法

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WO1988000976A1 (en) * 1986-07-25 1988-02-11 Louisiana State University And Agricultural And Me Method for introduction of disease and pest resistance into plants and novel genes incorporated into plants which code therefor
US5861478A (en) 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
KR970006154B1 (ko) * 1987-07-06 1997-04-24 루이지아나 스테이트 유니버시티 아그리컬춰럴 앤드 메카니칼 컬리지 용해성 펩티드에 의한 진핵 병원체와 신생물의 억제 및 섬유아세포와 임파구의 자극
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
WO1995001424A1 (en) * 1993-06-30 1995-01-12 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed mammalian cells capable of expressing cecropin b
WO1995001095A1 (en) * 1993-06-30 1995-01-12 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed eukaryotic cells, and transposon-based transformation vectors
US6156568A (en) * 1993-06-30 2000-12-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed eukaryotic cells
US5856178A (en) * 1993-08-30 1999-01-05 Utah State University DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
US5998698A (en) * 1995-06-07 1999-12-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transgenic fish capable of expressing exogenous lytic peptides
US6288212B1 (en) * 1998-08-28 2001-09-11 The University Of British Columbia Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor
US6982153B1 (en) 1998-12-03 2006-01-03 Targanta Therapeutics, Inc. DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
AU774841B2 (en) * 1998-12-03 2004-07-08 Targanta Therapeutics Inc. Development of novel anti-microbial agents based on bacteriophage genomics
WO2002014345A2 (en) * 2000-08-15 2002-02-21 North Carolina State University Antimicrobial peptides isolated from mast cells
US6753407B2 (en) 2000-08-15 2004-06-22 North Carolina State University Antimicrobial peptides isolated from fish
JP2004515251A (ja) 2000-12-19 2004-05-27 ファゲテック，インコーポレイティド スタフィロコッカス・アウレウス必須遺伝子及びそのコードされるタンパク質ｓｔａａｕ＿ｒ９に関連する組成物及び方法
US20080124787A1 (en) * 2001-02-13 2008-05-29 Avigenics, Inc. Microinjection devices and methods of use
US20050209157A1 (en) * 2001-03-28 2005-09-22 Owen Donald R Short bioactive peptides and methods for their use
EP2105141B1 (de) * 2001-03-28 2012-08-08 Helix Biomedix, Inc. Kurze bioaktive Peptide und Verwendungsverfahren
US6875744B2 (en) * 2001-03-28 2005-04-05 Helix Biomedix, Inc. Short bioactive peptides
DE60329382D1 (de) * 2002-04-22 2009-11-05 Dow Global Technologies Inc Kostengünstige herstellung von peptiden
US7527966B2 (en) * 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
US20040172667A1 (en) 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
AU2004211654B2 (en) * 2003-02-07 2009-03-05 Wisconsin Alumni Research Foundation Directed genetic modifications of human stem cells
WO2005062881A2 (en) 2003-12-24 2005-07-14 Transgenrx, Inc. Gene therapy using transposon-based vectors
US20050282755A1 (en) * 2004-03-18 2005-12-22 Ansata Therapeutics, Inc. Compositions having antimicrobial activity and uses thereof
WO2006086321A2 (en) * 2005-02-09 2006-08-17 Helix Biomedix Inc. Antimicrobial hexapeptides
US20070129690A1 (en) 2005-12-02 2007-06-07 Joel Rosenblatt Catheter with polymeric coating
US20080188830A1 (en) * 2007-02-06 2008-08-07 Arrow International, Inc. Selectively reinforced medical devices
US20090175967A1 (en) * 2008-01-04 2009-07-09 Nutracea Methods for treatment of intestinal carcinogenesis with rice bran
KR101863136B1 (ko) 2008-01-24 2018-05-31 에스퍼란스 파마슈티컬스, 인코포레이티드 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법
US9157097B2 (en) 2008-09-25 2015-10-13 Proteovec Holding, L.L.C. Vectors for production of growth hormone
US9150880B2 (en) 2008-09-25 2015-10-06 Proteovec Holding, L.L.C. Vectors for production of antibodies
US20100082097A1 (en) * 2008-10-01 2010-04-01 Joel Rosenblatt Article Containing Segregated Biguanide and Lewis Acid
WO2010118360A1 (en) 2009-04-09 2010-10-14 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Production of proteins using transposon-based vectors
IL238323B2 (en) 2012-10-30 2023-11-01 Esperance Pharmaceuticals Inc Antibody/drug conjugates and methods of use

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FR489987A (fr) 1917-07-04 1919-03-26 Otis Pifre Ateliers Sa Perfectionnement apporté aux tours et machines similaires
GB140556A (en) 1919-04-09 1920-04-01 Sidney George Palmer Improvements in and relating to the construction of buildings
BE723288A (de) * 1967-11-03 1969-04-01
US3911110A (en) 1972-12-22 1975-10-07 Canadian Patents Dev Insecticidal compositions
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
US4520016A (en) * 1980-06-17 1985-05-28 Kabigen Ab Bacteriolytic proteins
US4355104A (en) * 1980-06-17 1982-10-19 Kabigen Ab Bacteriolytic proteins
DE3023787A1 (de) * 1980-06-25 1982-01-21 Studiengesellschaft Kohle mbH, 4330 Mülheim Verfahren zur erhoehung der inkorporation und der expression von genetischem material in die kerne von intakten zellen mit hilfe von liposomen
WO1982003872A1 (en) 1981-04-27 1982-11-11 Washington Univ B.thuringiensis crystal protein in e.coli
US4579821A (en) * 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
GB8302512D0 (en) 1983-01-29 1983-03-02 Fbc Ltd Pesticidal method
NZ209338A (en) 1983-09-14 1988-02-12 Lubrizol Genetics Inc Plasmid for the transformation of a plant cell
BR8404834A (pt) 1983-09-26 1985-08-13 Agrigenetics Res Ass Metodo para modificar geneticamente uma celula vegetal
US4751081A (en) 1984-03-26 1988-06-14 Advanced Genetic Sciences, Inc. Chitinase-producing bacteria
US4643988A (en) 1984-05-15 1987-02-17 Research Corporation Amphipathic peptides
EP0184288A1 (de) 1984-10-23 1986-06-11 Schering Agrochemicals Limited Herbizide, Insektizide und Fungizide
JPS61122299A (ja) 1984-11-19 1986-06-10 Wakunaga Seiyaku Kk 抗菌性ポリペプチド、その製造法およびその用途
US5206154A (en) * 1985-01-28 1993-04-27 Xoma Corporation Method of producing cecropins by microbiological techniques
US5166321A (en) * 1985-01-28 1992-11-24 International Genetic Engineering, Inc. Cecropin polypetides with activity against Gram-positive and Gram-negative bacteria
DE3650625T2 (de) * 1985-01-28 1997-10-02 Xoma Corp AraB-Promoter und Verfahren zur Herstellung von Polypeptiden einschliesslich Cecropinen mittels mikrobiologischer Verfahren
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
WO1988000976A1 (en) 1986-07-25 1988-02-11 Louisiana State University And Agricultural And Me Method for introduction of disease and pest resistance into plants and novel genes incorporated into plants which code therefor
US4844924A (en) 1987-09-16 1989-07-04 A. E. Staley Manufacturing Company Esterified dietary fiber products and methods
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110754400A (zh) * 2019-10-28 2020-02-07 长江大学 一种提高黄鳝苗种人工孵化率的方法

Also Published As

Publication number Publication date
ATE120795T1 (de) 1995-04-15
KR890701746A (ko) 1989-12-21
US6303568B1 (en) 2001-10-16
DE3853535T2 (de) 1995-10-12
EP0365598A1 (de) 1990-05-02
CA1327311C (en) 1994-03-01
AU2071488A (en) 1989-01-30
EP0365598A4 (en) 1991-04-03
KR970005048B1 (ko) 1997-04-11
WO1989000199A1 (en) 1989-01-12
EP0365598B1 (de) 1995-04-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HELIX BIOMEDIX, INC., BATON ROUGE, LA., US

8327 Change in the person/name/address of the patent owner

Owner name: HELIX BIOMEDIX, INC., BOTHELL, WASH., US