DE3577549D1 - Dichloranilinderivate. - Google Patents
Dichloranilinderivate.Info
- Publication number
- DE3577549D1 DE3577549D1 DE8585307449T DE3577549T DE3577549D1 DE 3577549 D1 DE3577549 D1 DE 3577549D1 DE 8585307449 T DE8585307449 T DE 8585307449T DE 3577549 T DE3577549 T DE 3577549T DE 3577549 D1 DE3577549 D1 DE 3577549D1
- Authority
- DE
- Germany
- Prior art keywords
- group
- hydrogen atom
- alkyl
- formula
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- DADSZOFTIIETSV-UHFFFAOYSA-N n,n-dichloroaniline Chemical class ClN(Cl)C1=CC=CC=C1 DADSZOFTIIETSV-UHFFFAOYSA-N 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 125000006590 (C2-C6) alkenylene group Chemical group 0.000 abstract 1
- 125000006591 (C2-C6) alkynylene group Chemical group 0.000 abstract 1
- 206010006458 Bronchitis chronic Diseases 0.000 abstract 1
- 206010062109 Reversible airways obstruction Diseases 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000004419 alkynylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 208000007451 chronic bronchitis Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848426191A GB8426191D0 (en) | 1984-10-17 | 1984-10-17 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3577549D1 true DE3577549D1 (de) | 1990-06-13 |
Family
ID=10568291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8585307449T Expired - Fee Related DE3577549D1 (de) | 1984-10-17 | 1985-10-16 | Dichloranilinderivate. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0181709B1 (de) |
| JP (1) | JPS61143346A (de) |
| AT (1) | ATE52497T1 (de) |
| AU (1) | AU584929B2 (de) |
| CA (1) | CA1255667A (de) |
| DE (1) | DE3577549D1 (de) |
| DK (1) | DK474485A (de) |
| GB (2) | GB8426191D0 (de) |
| NZ (1) | NZ213840A (de) |
| PT (1) | PT82386B (de) |
| ZA (1) | ZA857928B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU581887B2 (en) * | 1984-04-17 | 1989-03-09 | Glaxo Group Limited | Ethanolamine compounds |
| GB8426191D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
| GB8525321D0 (en) * | 1985-10-15 | 1985-11-20 | Glaxo Group Ltd | Chemical compounds |
| GB8603475D0 (en) * | 1986-02-12 | 1986-03-19 | Glaxo Group Ltd | Chemical compounds |
| GB8703007D0 (en) * | 1987-02-10 | 1987-03-18 | Glaxo Group Ltd | Chemical compounds |
| EP0278727A3 (de) * | 1987-02-10 | 1990-03-14 | Glaxo Group Limited | 1-(4-Amino-3-chloro-5-trifluoromethylphenyl)-2-(substituierte amino)ethanol-Derivate und ihre Verwendung bei der Behandlung von Lungenkrankheiten |
| EP0286242A3 (de) * | 1987-03-12 | 1989-08-09 | Glaxo Group Limited | Ethanolamin-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Verbindungen |
| DE3714484A1 (de) * | 1987-04-30 | 1988-11-10 | Bayer Ag | Neue aminophenylethylamin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als leistungsfoerderer |
| GB8718939D0 (en) * | 1987-08-11 | 1987-09-16 | Glaxo Group Ltd | Chemical compounds |
| GB8718938D0 (en) * | 1987-08-11 | 1987-09-16 | Glaxo Group Ltd | Chemical compounds |
| IE883400L (en) * | 1987-11-13 | 1989-05-13 | Fuisz Technologies Ltd | Phenethanolamine derivatives |
| DE3884363T2 (de) * | 1987-12-18 | 1994-01-20 | Glaxo Group Ltd | Ethanolaminderivate. |
| ZA889405B (en) * | 1987-12-18 | 1989-12-27 | Glaxo Group Ltd | Ethanolamine derivatives |
| GB2230775A (en) * | 1989-04-24 | 1990-10-31 | Glaxo Group Ltd | Phenethanolamine compounds |
| GB8909273D0 (en) * | 1989-04-24 | 1989-06-07 | Glaxo Group Ltd | Chemical compounds |
| AU635424B2 (en) * | 1990-06-05 | 1993-03-18 | Glaxo Group Limited | Dichloroaniline compound |
| DE4028398A1 (de) * | 1990-09-07 | 1992-03-12 | Thomae Gmbh Dr K | Phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| JPH0744453U (ja) * | 1992-09-04 | 1995-11-21 | 中京製線株式会社 | 金属の伸線または引抜き用ダイスの冷却機構 |
| EP0664788A1 (de) * | 1992-10-16 | 1995-08-02 | Byk Nederland BV | Substituierte ethanolaminester |
| NZ539676A (en) | 2002-10-28 | 2006-10-27 | Glaxo Group Ltd | Phenethanolamine derivative for the treatment of respiratory diseases |
| GB0303396D0 (en) | 2003-02-14 | 2003-03-19 | Glaxo Group Ltd | Medicinal compounds |
| GB0329182D0 (en) | 2003-12-17 | 2004-01-21 | Glaxo Group Ltd | Chemical compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL176168C (nl) * | 1972-12-18 | 1985-03-01 | Thomae Gmbh Dr K | Werkwijze ter bereiding respectievelijk vervaardiging van een farmaceutisch preparaat en werkwijze ter bereiding van daarbij bruikbare nieuwe gesubstitueerde 1-(4-aminofenyl)-2-amino-ethanol-derivaten die, behalve een analgetische, uterusspasmolytische en anti-spastische werking op de dwarsgestreepte spieren, in het bijzonder een beta2-mimetische en/of beta1-blokkerende werking bezitten. |
| NL8105170A (nl) * | 1980-12-10 | 1982-07-01 | Thomae Gmbh Dr K | Nieuwe fenylalkylaminen, werkwijze ter bereiding daarvan en de toepassing daarvan als geneesmiddelen. |
| DE3306160A1 (de) * | 1983-02-22 | 1984-08-23 | Bayer Ag, 5090 Leverkusen | Wachstumsfoerdernde aminophenylethylamin-derivate |
| GB8426191D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
-
1984
- 1984-10-17 GB GB848426191A patent/GB8426191D0/en active Pending
-
1985
- 1985-10-16 GB GB08525487A patent/GB2165542B/en not_active Expired
- 1985-10-16 AT AT85307449T patent/ATE52497T1/de active
- 1985-10-16 ZA ZA857928A patent/ZA857928B/xx unknown
- 1985-10-16 NZ NZ213840A patent/NZ213840A/xx unknown
- 1985-10-16 DK DK474485A patent/DK474485A/da not_active Application Discontinuation
- 1985-10-16 EP EP85307449A patent/EP0181709B1/de not_active Expired - Lifetime
- 1985-10-16 DE DE8585307449T patent/DE3577549D1/de not_active Expired - Fee Related
- 1985-10-16 CA CA000493121A patent/CA1255667A/en not_active Expired
- 1985-10-16 AU AU48748/85A patent/AU584929B2/en not_active Ceased
- 1985-10-17 JP JP60232288A patent/JPS61143346A/ja active Pending
-
1986
- 1986-04-14 PT PT82386A patent/PT82386B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK474485D0 (da) | 1985-10-16 |
| EP0181709B1 (de) | 1990-05-09 |
| PT82386A (en) | 1986-05-01 |
| AU584929B2 (en) | 1989-06-08 |
| NZ213840A (en) | 1989-07-27 |
| PT82386B (pt) | 1988-08-17 |
| EP0181709A1 (de) | 1986-05-21 |
| JPS61143346A (ja) | 1986-07-01 |
| DK474485A (da) | 1986-04-18 |
| GB2165542A (en) | 1986-04-16 |
| CA1255667A (en) | 1989-06-13 |
| ATE52497T1 (de) | 1990-05-15 |
| AU4874885A (en) | 1986-06-12 |
| GB8525487D0 (en) | 1985-11-20 |
| GB2165542B (en) | 1988-05-05 |
| ZA857928B (en) | 1986-09-24 |
| GB8426191D0 (en) | 1984-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |