DE19903398A1 - Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen - Google Patents

Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen

Info

Publication number: DE19903398A1
Authority: DE; Germany
Prior art keywords: viruses; genus; bacteria; virus; family
Prior art date: 1999-01-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

DE19903398A

Other languages

German (de)

English (en)

Inventor

Hassan Jomaa

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Jomaa Pharmaka GmbH

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-29

Filing date

1999-01-29

Publication date

2000-08-10

1999-01-29 Application filed by Individual filed Critical Individual

1999-01-29 Priority to DE19903398A priority Critical patent/DE19903398A1/de

2000-01-27 Priority to PCT/EP2000/000613 priority patent/WO2000044359A2/fr

2000-01-27 Priority to AU27989/00A priority patent/AU2798900A/en

2000-08-10 Publication of DE19903398A1 publication Critical patent/DE19903398A1/de

Status Ceased legal-status Critical Current

Links

208000015181 infectious disease Diseases 0.000 title claims abstract description 13
150000004867 thiadiazoles Chemical class 0.000 title claims abstract description 11
238000011282 treatment Methods 0.000 title claims description 13
230000001225 therapeutic effect Effects 0.000 title abstract description 3
230000000069 prophylactic effect Effects 0.000 title 1
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-1 alkyl radicals Chemical class 0.000 claims description 122
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125000000753 cycloalkyl group Chemical group 0.000 claims description 11
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239000000825 pharmaceutical preparation Substances 0.000 claims description 9
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LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 claims description 8
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DZBUGLKDJFMEHC-UHFFFAOYSA-N acridine Chemical compound C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 claims description 4
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JFIOVJDNOJYLKP-UHFFFAOYSA-N bithionol Chemical compound OC1=C(Cl)C=C(Cl)C=C1SC1=CC(Cl)=CC(Cl)=C1O JFIOVJDNOJYLKP-UHFFFAOYSA-N 0.000 claims description 4
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WZOZEZRFJCJXNZ-ZBFHGGJFSA-N cefoxitin Chemical group N([C@]1(OC)C(N2C(=C(COC(N)=O)CS[C@@H]21)C(O)=O)=O)C(=O)CC1=CC=CS1 WZOZEZRFJCJXNZ-ZBFHGGJFSA-N 0.000 claims description 4
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WHTVZRBIWZFKQO-UHFFFAOYSA-N chloroquine Natural products ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-UHFFFAOYSA-N 0.000 claims description 4
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HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 claims description 4
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KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 claims description 4
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE19903398A 1999-01-29 1999-01-29 Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen Ceased DE19903398A1 (de)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
DE19903398A DE19903398A1 (de)	1999-01-29	1999-01-29	Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen
PCT/EP2000/000613 WO2000044359A2 (fr)	1999-01-29	2000-01-27	Utilisation de derives thiadiazoliques pour le traitement prophylactique et therapeutique d'infections
AU27989/00A AU2798900A (en)	1999-01-29	2000-01-27	Utilisation of thiadizole derivatives for the prophylactic and therapeutic treatment of infections

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19903398A DE19903398A1 (de)	1999-01-29	1999-01-29	Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen

Publications (1)

Publication Number	Publication Date
DE19903398A1 true DE19903398A1 (de)	2000-08-10

Family

ID=7895681

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE19903398A Ceased DE19903398A1 (de)	1999-01-29	1999-01-29	Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen

Country Status (3)

Country	Link
AU (1)	AU2798900A (fr)
DE (1)	DE19903398A1 (fr)
WO (1)	WO2000044359A2 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002100851A3 (fr) *	2001-06-11	2003-02-27	Shire Biochem Inc	Composes et procedes destines au traitement des infections par flavivirus
US7402608B2 (en)	2002-12-10	2008-07-22	Virochem Pharma Inc.	Compounds and methods for the treatment or prevention of Flavivirus infections
US7569600B2 (en)	2005-05-13	2009-08-04	Virochem Pharma Inc.	Compounds and methods for the treatment of prevention of Flavivirus infections
US8003685B2 (en)	2006-11-15	2011-08-23	Vertex Pharmaceuticals (Canada) Incorporated	Thiophene analogues for the treatment or prevention of flavivirus infections
US8329924B2 (en)	2001-06-11	2012-12-11	Vertex Pharmaceuticals (Canada) Incorporated	Compounds and methods for the treatment or prevention of Flavivirus infections

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ES2824261T3 (es) *	2007-09-14	2021-05-11	Biogen Ma Inc	Composiciones y procedimientos para el tratamiento de la leucoencefalopatía multifocal progresiva (LMP)
CN102626415B (zh) *	2012-03-21	2014-08-06	山东省千佛山医院	四环素类药物联合应用氟康唑在制备抗真菌产品中的应用及其产品
EP3082821A4 (fr) *	2013-11-14	2017-06-07	Avista Pharma Solutions, Inc.	Composes antiparasitaires
EP3967312A1 (fr)	2014-09-12	2022-03-16	UNION therapeutics A/S	Utilisation antibactérienne de salicylanilides halogénés
CN104606215B (zh) *	2014-12-31	2017-10-10	中国医学科学院病原生物学研究所	一种抑制肠道病毒71的药物
GB201509326D0 (en)	2015-05-29	2015-07-15	Antibio Tx Aps	Novel use
US11419834B2 (en)	2019-02-25	2022-08-23	Rhode Island Hospital	Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
CN112294795B (zh) *	2020-11-17	2022-03-29	北京化工大学	蒿甲醚在治疗和预防柯萨奇病毒感染中的应用
CN115109053A (zh) *	2022-06-08	2022-09-27	深圳湾实验室	噻唑亚磺酰基噻二唑类衍生物、中间体、制备方法以及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07233069A (ja) *	1994-02-18	1995-09-05	Sagami Chem Res Center	１，２，３−チアジアゾール誘導体を有効成分とする５−リポキシゲナーゼ阻害剤
JPH07233157A (ja) *	1994-02-18	1995-09-05	Sagami Chem Res Center	１，２，３−チアジアゾール誘導体

1999
- 1999-01-29 DE DE19903398A patent/DE19903398A1/de not_active Ceased
2000
- 2000-01-27 WO PCT/EP2000/000613 patent/WO2000044359A2/fr not_active Ceased
- 2000-01-27 AU AU27989/00A patent/AU2798900A/en not_active Abandoned

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2363396A1 (fr) *	2001-06-11	2011-09-07	Virochem Pharma Inc.	Dérivés de thiophène comme agents antivirales contre des infections par flavivirus
US6881741B2 (en)	2001-06-11	2005-04-19	Virochem Pharma Inc.	Compounds and methods for the treatment or prevention of Flavivirus infections
EA007484B1 (ru) *	2001-06-11	2006-10-27	Вирокем Фарма Инк.	Соединения и способы лечения или предупреждения инфекций flavivirus
WO2002100851A3 (fr) *	2001-06-11	2003-02-27	Shire Biochem Inc	Composes et procedes destines au traitement des infections par flavivirus
US8329924B2 (en)	2001-06-11	2012-12-11	Vertex Pharmaceuticals (Canada) Incorporated	Compounds and methods for the treatment or prevention of Flavivirus infections
EP2206709A3 (fr) *	2001-06-11	2011-06-29	Virochem Pharma Inc.	Dérivés de thiophène comme agents antiviraux contre les infections à flavivirus
US7985769B2 (en)	2001-06-11	2011-07-26	Vertex Pharmaceuticals Incorporated	Compounds and methods for the treatment or prevention of Flavivirus infections
US8357718B2 (en)	2002-12-10	2013-01-22	Vertex Pharmaceuticals (Canada) Incorporated	Compounds and methods for the treatment or prevention of flavivirus infections
US7402608B2 (en)	2002-12-10	2008-07-22	Virochem Pharma Inc.	Compounds and methods for the treatment or prevention of Flavivirus infections
US8829030B2 (en)	2002-12-10	2014-09-09	Vertex Pharmaceuticals (Canada) Incorporated	Compounds and methods for the treatment or prevention of Flavivirus infections
US8158675B2 (en)	2005-05-13	2012-04-17	Vertex Pharmaceuticals (Canada) Incorporated	Compounds and methods for the treatment or prevention of Flavivirus infections
US7569600B2 (en)	2005-05-13	2009-08-04	Virochem Pharma Inc.	Compounds and methods for the treatment of prevention of Flavivirus infections
US8674118B2 (en)	2005-05-13	2014-03-18	Vertex Pharmaceuticals Incorporated	Compounds and methods for the treatment or prevention of flavivirus infections
US8003685B2 (en)	2006-11-15	2011-08-23	Vertex Pharmaceuticals (Canada) Incorporated	Thiophene analogues for the treatment or prevention of flavivirus infections
US8269014B2 (en)	2006-11-15	2012-09-18	Vertex Pharmaceuticals (Canada) Incorporated	Thiophene analogues for the treatment or prevention of flavivirus infections
US8658674B2 (en)	2006-11-15	2014-02-25	Vertex Pharmaceuticals Incorporated	Thiophene analogues for the treatment or prevention of flavivirus infections

Also Published As

Publication number	Publication date
WO2000044359A2 (fr)	2000-08-03
AU2798900A (en)	2000-08-18
WO2000044359A3 (fr)	2000-09-28

Publication	Publication Date	Title
EP1071409B1 (fr)	2003-10-15	Utilisation de liaisons organophosphorees dans le traitement et la prevention d'infections
DE19903398A1 (de)	2000-08-10	Verwendung von Thiadiazolderivaten zur prophylaktischen und therapeutischen Behandlung von Infektionen
DE19920247A1 (de)	2000-11-16	Arzneimittel mit einem Gehalt an Verbindungen mit einem Stickstoff-Sauerstoff-Heterocyclus als Wirkstoff und ihre Verwendung
DE19859426A1 (de)	2000-07-06	Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen
EP1140113B1 (fr)	2003-11-05	Utilisation de bisphosphonates pour la prophylaxie et le traitement de processus infectieux
EP1133500B1 (fr)	2002-09-11	Composes phosphororganiques et leur utilisation
WO2000016757A2 (fr)	2000-03-30	Utilisation de composes organophosphores pour la production de medicaments pour le traitement therapeutique et prophylactique d'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux
DE19843383A1 (de)	2000-03-30	Phosphororganische Verbindungen und ihre Verwendung
DE19902924A1 (de)	2000-08-03	Verwendung von phosphororganischen Verbindungen zur prophylaktischen und therapeutischen Behandlung von Infektionen
DE19854402A1 (de)	2000-05-31	Verwendung von Phosphonameisensäurederivaten zur therapeutischen und prophylaktischen Behandlung von Infektionen
DE19843223A1 (de)	2000-03-30	Phosphororganische Verbindungen und ihre Verwendung
EP1255762A1 (fr)	2002-11-13	Composes organophosphores et leur utilisation
EP1272198A1 (fr)	2003-01-08	Utilisation de composes organophosphores pour la fabrication d'un medicament destine au traitement d'infections
DE19859668A1 (de)	1999-12-30	Verwendung von Bisphosphonaten zur Prophylaxe und zur Behandlung von infektiösen Prozessen
DE19843334A1 (de)	2000-03-30	Schwefelorganische Verbindungen und ihre Verwendung
WO2001093872A1 (fr)	2001-12-13	Utilisation de derives d'acide hydroxamique organophosphores pour la fabrication de medicaments
DE19854310A1 (de)	2000-06-29	Verwendung von Phosphonoameisensäurederivaten zur therapeutischen und prophylaktischen Behandlung von Infektionen
DE19843360A1 (de)	2000-03-30	Phosphororganische Verbindungen und ihre Verwendung
DE19903666A1 (de)	2000-08-03	Arzneimittel mit einem Gehalt an 3-Isoxazolidinonen und Hydroxylaminsäuren als Wirkstoff und ihre Verwendung
EP1143941A2 (fr)	2001-10-17	Utilisation de 3-isoxazolidinones et d'hydroxylaminoacides pour le traitement d'infections
CZ2001989A3 (cs)	2001-07-11	Použití fosfororganických sloučenin pro výrobu léčiv pro terapeutické a profylaktické ošetřování infekcí nebo jako fungicid, baktericid či herbicid u rostlin
AU2003261554A1 (en)	2003-12-04	Organophosphorus containing preparations and applications therefor

Legal Events

Date	Code	Title	Description
2000-08-10	OP8	Request for examination as to paragraph 44 patent law
2002-05-16	8127	New person/name/address of the applicant	Owner name: JOMAA PHARMAKA GMBH, 35392 GIESSEN, DE
2002-05-16	8181	Inventor (new situation)	Free format text: JOMAA, HASSAN, DR., 35398 GIESSEN, DE
2003-06-18	8131	Rejection