DE1617939C3 - Toothpaste - Google Patents
ToothpasteInfo
- Publication number
- DE1617939C3 DE1617939C3 DE19661617939 DE1617939A DE1617939C3 DE 1617939 C3 DE1617939 C3 DE 1617939C3 DE 19661617939 DE19661617939 DE 19661617939 DE 1617939 A DE1617939 A DE 1617939A DE 1617939 C3 DE1617939 C3 DE 1617939C3
- Authority
- DE
- Germany
- Prior art keywords
- toothpaste
- weight
- inorganic salt
- percent
- sodium bicarbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000606 toothpaste Substances 0.000 title claims description 24
- 229940034610 toothpaste Drugs 0.000 title claims description 21
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 235000002639 sodium chloride Nutrition 0.000 claims description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 229910017053 inorganic salt Inorganic materials 0.000 claims description 7
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 6
- 239000011780 sodium chloride Substances 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 5
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 5
- 239000001095 magnesium carbonate Substances 0.000 claims description 5
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 5
- 239000006072 paste Substances 0.000 claims description 5
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 claims description 5
- 229910052939 potassium sulfate Inorganic materials 0.000 claims description 5
- 235000011151 potassium sulphates Nutrition 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 229910019142 PO4 Inorganic materials 0.000 claims description 3
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 claims description 3
- 239000008119 colloidal silica Substances 0.000 claims description 3
- 230000007935 neutral effect Effects 0.000 claims description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- 239000010452 phosphate Substances 0.000 claims description 3
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 3
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 3
- 239000000080 wetting agent Substances 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- 239000000645 desinfectant Substances 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- 235000010356 sorbitol Nutrition 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 239000001120 potassium sulphate Substances 0.000 claims 1
- 208000002193 Pain Diseases 0.000 description 7
- 230000036407 pain Effects 0.000 description 7
- 210000003739 neck Anatomy 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 230000001680 brushing effect Effects 0.000 description 3
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 208000035154 Hyperesthesia Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 241000186660 Lactobacillus Species 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 229960004050 aminobenzoic acid Drugs 0.000 description 2
- 210000004268 dentin Anatomy 0.000 description 2
- 230000009610 hypersensitivity Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000005239 tubule Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- SUZRRICLUFMAQD-UHFFFAOYSA-N N-Methyltaurine Chemical compound CNCCS(O)(=O)=O SUZRRICLUFMAQD-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 235000021270 cold food Nutrition 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000007596 consolidation process Methods 0.000 description 1
- 230000006003 cornification Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 235000021268 hot food Nutrition 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 235000014380 magnesium carbonate Nutrition 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 229940124641 pain reliever Drugs 0.000 description 1
- 230000008533 pain sensitivity Effects 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 230000000395 remineralizing effect Effects 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/445—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Description
Die Erfindung betrifft eine Zahnpaste, die neben einem besonders milden Putzkörper-Bindemittel-Glycerin-Wasser-Gemisch eine spezifische anorganische Salzkombination sowie Para'aminobenzoesäureäthylester enthält.The invention relates to a toothpaste which, in addition to a particularly mild cleaning agent-binding agent-glycerine-water mixture a specific inorganic salt combination and Para'aminobenzoic acid ethyl ester contains.
Ein großer Personenkreis, der seine Zähne sorgfältig und regelmäßig mittels normalen Zahnpasten reinigt, muß zu irgendeinem Zeitpunkt feststellen, daß trotz scheinbar bester Pflege das Zahnfleisch zurückweicht und die Zahnhälse zunehmend frei liegen. Jetzt haben die Lactobazillen im Schutz von Zahn-Plaques entlang dem Zahnfleischsaum die Möglichkeit, den Zahnschmelz systematisch zu decalcifizieren. Hinzu kommt die oft nicht unerhebliche mechanische Abrasion von Prothesenklammern. Das Fortschreiten der Beschädigung wird von heftigen Schmerzen am frei liegenden Dentin begleitet. Diese Schmerze'n treten bei jedem Genuß von Süßigkeiten, kalten oder heißen Speisen, oft sogar während des Sprechens durch kalten Luftzug auf.A large group of people who have their teeth carefully and regularly using normal toothpastes cleans, must at some point find that the gums are receding despite the apparently best care and the tooth necks are increasingly exposed. Now the lactobacilli are protected by dental plaques the possibility of systematically decalcifying the enamel along the gum line. In addition comes the often not inconsiderable mechanical abrasion of prosthesis clips. The progression of the Damage is accompanied by severe pain in the exposed dentin. These pains occur every enjoyment of sweets, cold or hot food, often even while speaking through cold ones Draft on.
Trotz der heftigen Belästigungen, die die Hypersensibilität oder Hyperästesie der Zahnhälse bei den Betroffenen auslösen, stellt diese'selbst nach Professor K e 11 e r 1, Mainz, keinen physiologischen Zustand dar und läßt sich nicht pathologisch-anatomisch erklären. Die Hyperästhesie ist keine Krankheit und bedarf deshalb, wie Professor K e 11 e r 1 ausdrücklich feststellt, keiner besonderen Therapie.Despite the violent annoyance, the hypersensitivity or cause hyperaesthesia of the tooth necks in those affected, according to Professor K e 11 e r 1, Mainz, does not represent a physiological condition and cannot be considered pathological-anatomical to explain. Hyperesthesia is not a disease and, like Professor K e 11 e r 1, is therefore expressly required notes no special therapy.
Alle Mittel, die der Linderung oder Beseitigung dieser Überempfindlichkeit dienen, sind deshalb, genau wie die nachbeschriebene Zahnpaste, reine Vorbeugungsmittel.All means that serve to alleviate or eliminate this hypersensitivity are therefore just like the toothpaste described below, purely preventive.
Alle zum Zeitpunkt der Erstbenützung dieser Zahnpaste bereits bestehenden Zahnschäden bedürfen selbstverständlich, 'wie seither, der Behandlung und Sanierung durch den Zahnarzt.All at the time of first use of this toothpaste Existing tooth damage naturally requires, as since then, treatment and Restoration by the dentist.
Für die zahnärztliche Praxis sind eine Reihe Präparate bekannt, die, vom Zahnarzt unmittelbar auf die gefährdeten Stellen appliziert, für längere oder kürzere Zeit dem Auftreten der schmerzhaften Zustände vorbeugen sollen. So versucht man beispielsweise die Tubuliöffnungen mittels Kunststofflack zu touchieren und auf diese Weise einen Verschluß herbeizuführen. Jedoch setzt die Kauabnutzung dem Erfolg dieser Behandlungsmethode relativ enge Grenzen.A number of preparations are known for the dental practice, which, by the dentist directly on the Applied to endangered areas, prevent the occurrence of painful conditions for a longer or shorter period of time should. For example, one tries to touch the tubule openings with plastic varnish and in this way to bring about a closure. However, the chew wear continues to the success of these Treatment method relatively narrow limits.
ίο Es wurden Pasten entwickelt, die vom Zahnarzt in Art eines Verbandes entlang den Zahnfleischsäumen aufgelegt werden und dort über Stunden verbleiben müssen. Sie enthalten zwecks Remineralisierung anorganische Salzkombinationen nach dem Modell »Emser Salz«. Auch versucht man fester haftende Niederschläge auf der Zahnoberfläche auszufällen, indem man mit Silicofluoridlösung vortouchiert und mit Calciumhydroxyd versetzt.ίο Pastes have been developed to be used by the dentist in Kind of a bandage along the gum line and remain there for hours have to. For the purpose of remineralization, they contain inorganic salt combinations according to the model "Emser Salt". Attempts are also made to precipitate more firmly adhering deposits on the tooth surface, by pre-touching with silicofluoride solution and adding calcium hydroxide.
Auch eine Zahnpaste, die mittels 1,4% Formaldehydanteil eine Verhornung des Schleimhautepithels verursacht, ist bekannt. Alle vorbeschriebenen Präparate verhindern die mit der Decalcifizierung ver- f bundene Schmerzempfindlichkeit nur in dem Maße, ^ wie es gelingt, die Tubuliöffnungen gegen das Mundmilieu abzuschließen.A toothpaste that causes cornification of the mucous membrane epithelium by means of 1.4% formaldehyde is also known. All prescribed drugs prevent comparable with the decalcification f Thematic pain sensitivity only to the extent that ^ how they manage to complete the tubule against the oral environment.
Da bei vielen Menschen die Furcht vor möglichen Zahnschmerzen so groß ist, daß sie, um der Gefahr einer schmerzhaften Berührung zu entgehen, die regelmäßige und notwendige Pflege ihres Gebisses verabsäumen, war es Aufgabe der Erfindung, eine Zahnpaste herzustellen, die im üblichen Gebrauch beim Zähneputzen dem Aufkommen eines Schmerzgefühls vorbeugt und gleichzeitig das Auftreten oder ein Fortschreiten der Decalcifizierung verhütet.Because with many people the fear of a possible toothache is so great that they in order to avoid the danger to avoid a painful touch, neglect the regular and necessary care of your teeth, It was an object of the invention to produce a toothpaste that is used in normal use Brushing your teeth prevents the onset of pain and at the same time prevents it from occurring or progressing prevent decalcification.
Gegenstand der Erfindung ist eine Zahnpaste, die dadurch gekennzeichnet ist, daß sie p-Aminobenzoesäureäthylester in einer Menge von 0,05 bis 4,0 Gewichtsprozent, bezogen auf die gesamte Zahnpastenmasse, eine anorganische Salzkombination aus Natriumbicarbonat, Natriumchlorid und Kaliumsulfat und/oder Magnesiumcarbonat, und als Putzkörper neutrales Erdalkaliphosphat und kolloidale Kieselsäure enthält.The invention relates to a toothpaste which is characterized in that it contains ethyl p-aminobenzoate in an amount of 0.05 to 4.0 percent by weight, based on the total toothpaste mass, an inorganic salt combination of sodium bicarbonate, sodium chloride and potassium sulfate and / or magnesium carbonate, and as a cleaning body neutral alkaline earth phosphate and colloidal silica contains.
Die Verwendung von p-Aminobenzoesäureäthyl- ( ester als schmerzstillender Zusatz zu Cremes und Salben oder auch in Lutschpastillen zur Behandlung des Mund- und Rachenraumes ist an sich bekannt. Die Verwendung dieser Komponente in Zahnpasten ist bisher jedoch noch nicht vorgeschlagen worden. Für ihre Verwendung im Zusammenhang mit der Erfindung ist die nicht vorhersehbare Tatsache von entscheidender Bedeutung, daß die schmerzstillende Wirkung des . Anästhesins so schnell eintritt, daß selbst beim Zähneputzen, bei dem ja doch gleichzeitig mit dem Aufbringen der Zahnpaste die schmerzempfindlichen Partien der Zahnhälse mechanisch bearbeitet werden, eine kurzfristige wirkliche Schmerzmilderung eintritt.The use of p-aminobenzoic acid ethyl- ( Ester as a pain reliever additive to creams and ointments or in lozenges for treatment of the mouth and throat is known per se. The use of this component in toothpastes is however, it has not yet been proposed. For their use in connection with the invention the unpredictable fact is of crucial importance that the analgesic effects of the . Anesthesia occurs so quickly that even when brushing your teeth, which is at the same time as it is applied the toothpaste the pain-sensitive parts of the tooth necks are mechanically processed, there is real short-term pain relief.
Bedeutungsvoll ist dabei insbesondere auch, daß dieIt is particularly important that the
an sich praktisch wasserunlösliche Verbindung sich kraft großen Kriechvermögens so günstig im Mundbereich verteilt, daß schon die geringen Mengen von 0,05 bis 4,0%, besonders 0,1 bis 0,15%, bezogen auf die gesamte Zahnpastenmasse, genügen, um momen- ' ■ tanen Schmerzemplindungen vorzubeugen. '■In itself a practically water-insoluble compound, due to its great creeping ability, is so beneficial in the mouth area distributed that even the small amounts of 0.05 to 4.0%, especially 0.1 to 0.15%, based on the entire toothpaste mass, enough to momen- '■ to prevent tan painful sensations. '■
Die erlindungsgemäße Zahnpaste soll nun aber nicht nur während der kurzen Zeitdauer des Zähneputzens die Schmerzempfindlichkeit beseitigen, der regelmäßige Gebrauch der Zahnpaste soll vielmehr zuThe toothpaste according to the invention should now not only eliminate the sensitivity to pain during the short period of time brushing your teeth, that Rather, regular use of the toothpaste is said to be too
einem praktisch vollständigen Abklingen der störenden Schmerzerscheinungen führen. Diese Aufgabenstellung wird durch die Mitverwendung der Mineralsalze und insbesondere in Verbindung damit auch durch die remineralisierenden Spezialputzkörper erreicht. Ihre Gegenwart in der erfindungsgemäßen Zahnpaste beugt der Decalcifizierung vor und führt zur Festigung des Zahnfleisches mittels Osmose. Die Bestandteile dieser Salzkombination sind Natriumbicarbonat, Natriumchlorid und gegebenenfalls zusätzlich Kaliumsulfat und/oder Magnesiumcarbonat. Der Anteil an Natriumbicarbonat ist günstigerweise größer als der Natriumchloridanteil. Der Gesamtgehalt der fertigen Paste für das Gemisch Natriumbicarbonat, Natriumchlorid, Kaliumsulfat und Magnesiumcarbonat liegt vorzugsweise im Bereich von 5 bis 25 Gewichtsprozent, bezogen auf das Gewicht der Gesamtpaste. Die in dem folgenden Beispiel beschriebenen anorganischen Salzkombinationen weichen in ihrer analytischen Zusammensetzung von dem vorher erwähnten »Emser Salz« ab.lead to a practically complete disappearance of the disturbing symptoms of pain. This task is made possible by the use of mineral salts and, in particular, by the remineralizing special plaster body achieved. Their presence in the toothpaste according to the invention prevents decalcification and leads to consolidation of the gums using osmosis. The components of this salt combination are sodium bicarbonate, sodium chloride and optionally additionally potassium sulfate and / or magnesium carbonate. The proportion of Sodium bicarbonate is favorably larger than the sodium chloride content. The total of the finished Paste for the mixture of sodium bicarbonate, sodium chloride, potassium sulfate and magnesium carbonate lies preferably in the range from 5 to 25 percent by weight, based on the weight of the total paste. The in that Inorganic salt combinations described in the following example differ in their analytical composition from the aforementioned "Emser Salt".
Für die Erfindung ist es zweckmäßig, das Natriumbicarbonat, das eventuell frei liegendes Dentin in Gegenwart von Glycerin besonders günstig zu beeinflussen vermag, in gesättigten Lösungen zu verarbeiten. Dadurch wird der pH-Wert der fertigen Paste auf nahe 8,0 gestellt. Gleichzeitig wird die durch Lactobazillen in den Plaques gebildete Milchsäure weitgehend neutralisiert.For the invention it is expedient to use the sodium bicarbonate, to influence the possibly exposed dentine particularly favorably in the presence of glycerine able to process in saturated solutions. This will raise the pH of the finished paste placed near 8.0. At the same time, the lactic acid formed in the plaques by lactobacilli is largely reduced neutralized.
Als Putzkörper enthält die erfindungsgemäße Zahnpaste besonders mild wirkende Bestandteile, nämlich neutrales Erdalkaliphosphat und/oder kolloide Kieselsäure. Mit diesen Putzkörpern wird eine besonders schonende Reinigung der Zähne ohne mechanische Reizung des Zahnfleisches und der Zahnhälse erreicht.As a cleaning body, the toothpaste according to the invention contains particularly mild components, namely neutral alkaline earth phosphate and / or colloidal silica. With these cleaning bodies one becomes special Gentle cleaning of the teeth achieved without mechanical irritation of the gums and the tooth necks.
Vorzugsweise enthält die Zahnpaste zusätzlich übliche Desinfektionsmittel, z. B. p-Oxybenzoesäuremethylester und/oder das Natriumsalz davon sowie Netzmittel, wobei Netzmittelgehalte von 0,5 bis 5% bevorzugt werden.The toothpaste preferably also contains conventional disinfectants, e.g. B. p-Oxybenzoic acid methyl ester and / or the sodium salt thereof and wetting agents, with wetting agent contents of 0.5 to 5% to be favoured.
Es werden in an sich bekannter Weise zwei Zahnpasten (I und II) hergestellt, die der Erfindung entsprechen: Two toothpastes (I and II) are produced in a manner known per se, which correspond to the invention:
p-Aminobenzoesäureäthylester..ethyl p-aminobenzoate ..
Äthylalkohol, rein 94,6°/0ig Ethyl alcohol, pure 94.6% / 0 ig
kolloid. Kieselsäure colloid. Silica
Magnesiumcarbonat Magnesium carbonate
Natriumchlorid Sodium chloride
Kaliumsulfat Potassium sulfate
Natriumbicarbonat Sodium bicarbonate
Tricalciumphosphat Tricalcium phosphate
Glycerin Glycerin
Sorbit, 70%ig Sorbitol, 70%
p-Oxybenzoesäuremethylestermethyl p-oxybenzoate
Na-SaIz Na-SaIz
Natriumlaurylsulfat Sodium lauryl sulfate
Ölsäuremethyltaurin-Na Oleic acid methyl taurine Na
Carboxymethylcellulose Carboxymethyl cellulose
Titandioxyd Titanium dioxide
Aroma, evtl. Farbstoff Aroma, possibly coloring
Süßstoff sweetener
Wasser water
Beispiel I I ΠExample I I Π
0,125 2,375 3,000 1,250 0,175 0,175 6,250 9,000 24,0000.125 2.375 3.000 1.250 0.175 0.175 6.250 9.000 24.000
0,200 2,750 0,900 1,250 0,750 1,500 0,250 46,0500.200 2.750 0.900 1.250 0.750 1.500 0.250 46.050
100,000100,000
0,125 2,375 3,0000.125 2.375 3.000
0,7500.750
5,000 12,0005,000 12,000
8,100 13,1008,100 13,100
0,200 2,250 0,750 1,250 0,750 2,000 0,250 48,1000.200 2.250 0.750 1.250 0.750 2.000 0.250 48.100
100,000100,000
Claims (5)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEW0041824 | 1966-06-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE1617939A1 DE1617939A1 (en) | 1971-04-01 |
| DE1617939B2 DE1617939B2 (en) | 1973-11-08 |
| DE1617939C3 true DE1617939C3 (en) | 1974-06-12 |
Family
ID=7602982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19661617939 Expired DE1617939C3 (en) | 1966-06-21 | 1966-06-21 | Toothpaste |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE1617939C3 (en) |
| NL (1) | NL156599B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ226067A (en) * | 1987-09-11 | 1990-07-26 | Colgate Palmolive Co | An appetite suppressant oral composition containing benzocaine |
| US5326554A (en) * | 1993-04-23 | 1994-07-05 | The Procter & Gamble Company | Oral compositions for treating plaque and gingivitis |
| CA2300456C (en) * | 1999-03-12 | 2004-05-11 | Pfizer Products Inc. | Compositions comprising a potassium salt active ingredient, including oral compositions for reducing dental nerve and dentin sensitivity comprising a non-menthol flavoring |
-
1966
- 1966-06-21 DE DE19661617939 patent/DE1617939C3/en not_active Expired
-
1967
- 1967-06-21 NL NL6708635A patent/NL156599B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE1617939B2 (en) | 1973-11-08 |
| NL6708635A (en) | 1967-12-22 |
| DE1617939A1 (en) | 1971-04-01 |
| NL156599B (en) | 1978-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) | ||
| E77 | Valid patent as to the heymanns-index 1977 | ||
| 8339 | Ceased/non-payment of the annual fee |