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DE10005329A1 - Stimulating growth of hair, e.g. on the head, eyebrows or eyelashes, by subcutaneous application of a preparation containing stem cells and/or preformed hair cells - Google Patents

Stimulating growth of hair, e.g. on the head, eyebrows or eyelashes, by subcutaneous application of a preparation containing stem cells and/or preformed hair cells

Info

Publication number
DE10005329A1
DE10005329A1 DE10005329A DE10005329A DE10005329A1 DE 10005329 A1 DE10005329 A1 DE 10005329A1 DE 10005329 A DE10005329 A DE 10005329A DE 10005329 A DE10005329 A DE 10005329A DE 10005329 A1 DE10005329 A1 DE 10005329A1
Authority
DE
Germany
Prior art keywords
hair
cannulas
previous
cells
stem cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10005329A
Other languages
German (de)
Inventor
Albert Scheller
Wiliam Rader
Klaus Rennebeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE10005329A priority Critical patent/DE10005329A1/en
Priority to PCT/EP2001/001354 priority patent/WO2001058413A1/en
Publication of DE10005329A1 publication Critical patent/DE10005329A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • C12N5/0628—Hair stem cells; Hair progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985—Skin or skin outgrowth, e.g. hair, nails
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Stimulating growth of hair on a body region involves applying a preparation (I) containing stem cells and/or preformed hair cells subcutaneously to the region. Independent claims are included for the following: (i) a kit for carrying out a hair growth stimulation treatment, including a preparation containing stem cells and/or preformed hair cells; and (ii) the use of stem cells for stimulating hair growth. - ACTIVITY : Anti-alopecia. - MECHANISM OF ACTION : None given.

Description

In der anthropologischen Entwicklung wurden und werden wässrige Xeno-Pigmente zur dauerhaften Hautfärbung subkutan angewandt. In einer erfindungsgemäßen Fortentwicklung werden wässrige oder isoosmotische Flüssigkeiten, vorzugsweise mit preformierten Haarzellen oder embryonale, fetale Haarbildungszellen aus Nabelschnurblut, auch aus juvenilen und adulten Stammzellen, sowie durch Nichtdifferenzierung, Differenzierung und Redifferenzierung subkutan unter die vitale Haut, für die Haarbewachsung gebracht. Erfindungsgemäß werden so vitale blonde, fuchsige und schwarze Haare bei einer Haarwiederbewachsung erreicht. Unter der gleichen vitalen Haut zeigte sich überraschend, sind diese Haarfarben simultan dauerhaft gewachsen. Auf diese erfindungsgemäße Weise werden im Xenopi-Verfahren Wimpern und Augenbrauen wieder oder neu behaart. Erfindungsgemäß wird im Xenopi-Mikro-Multi- oder Einfach-Kanülen-Verfahren die Haarbewachsung subkutan eingebracht. Erfindungsgemäß wird ein Multi-Kanülen-Rad zur manuellen oder maschinellen Haarsubstrateinbringung benutzt.In anthropological development, water became and becomes watery Xeno-pigments are used subcutaneously for permanent skin coloring. In a Further developments according to the invention are aqueous or isoosmotic Liquids, preferably with preformed hair cells or embryonic, fetal hair cells from umbilical cord blood, also from juvenile and adult stem cells, as well as by non-differentiation, Differentiation and redifferentiation subcutaneously under the vital skin, for brought the hair waxing. According to the invention, vital blond, foxy and black hair reached during hair regrowth. Under the same vital skin, these were surprising Hair colors have grown permanently simultaneously. On this invention In the Xenopi procedure, eyelashes and eyebrows become wise again or new haired. According to the invention in Xenopi micro or multi Simple cannula procedure introduced the hair waxing subcutaneously. According to the invention, a multi-cannula wheel for manual or machine hair substrate insertion used.

Erfindungsgemäß werden Mikro-Multi-Kanülen-Bündel mit einer linearen und Tackerhubbewegung benutzt, wobei der Antrieb elektrisch oder pneumatisch erfolgt. Erfindungsgemäß werden die Kanülen durch Eintauchen befüllt. Erfindungsgemäß und vorzugsweise werden die Kanülen über Infusionsgarnituren versorgt. Erfindungsgemäß werden in einer Anwendung Braunülen zur Haarsubstrateinbringung eingesetzt. Erfindungsgemäß und vorzugsweise werden die zu behaarenden Hautflächen vorher subkutan eingefärbt. Erfindungsgemäß werden die Haarkanäle durch die subkutanen Kanüleneindringtiefen ausgebildet. Erfindungsgemäß werden mit dem Xenopi-Kanülen-Verfahren in der Minute 20 bis 1200 subkutane Haarkanäle ausgebildet und simultan die Haarbewachsung erreicht.According to the invention, micro-multi-cannula bundles with a linear and tacker stroke movement, the drive being electric or pneumatically. According to the cannulas Immersion filled. According to the invention and preferably Cannulas supplied via infusion sets. According to the invention an application Braunulen used for hair substrate insertion. According to the invention and preferably those to be haired Skin areas previously stained subcutaneously. According to the Hair channels are formed through the subcutaneous cannula penetration depths. According to the Xenopi cannula method in the Minute 20 to 1200 subcutaneous hair channels are formed and simultaneously the Hair growth reached.

Claims (11)

1. Humanisiertes, vitalisiertes Haarbewachsen und Haarwiederbewachsen mit subkutanen Kanüleneinstich-Haut-Färbungs-Zeichnungsverfahren nach dadurch gekennzeichnet, daß subkutan mit Kanüleneinstichen wässrige oder isoosmotische Flüssigkeiten für Haarbewuchs eingebracht werden.1. Humanized, vitalized hair regrowth and hair regrowth with subcutaneous cannula puncture skin coloring drawing method according to characterized in that aqueous or isoosmotic liquids for hair growth are introduced subcutaneously with cannula punctures. 2. Nach Anspruch 1 dadurch gekennzeichnet, daß preformierte Haarzellen über Kanülen mit eingebracht werden.2. According to claim 1, characterized in that preformed hair cells can be introduced via cannulas. 3. Nach Anspruch 1 dadurch gekennzeichnet, daß embryonale, fetale aus Nabelschnurblut, Haarbildungszellen und juvenile oder adulte Stammzellen mit eingebracht werden.3. According to claim 1, characterized in that embryonic, fetal Umbilical cord blood, hair cells and juvenile or adult Stem cells can be introduced. 4. Nach Anspruch 1 dadurch gekennzeichnet, daß durch Nichtdifferenzierung, Differenzierung und Redifferenzierung von Stammzellen eine Haarbewachsung erreicht wird.4. According to claim 1, characterized in that by non-differentiation, Differentiation and redifferentiation of stem cells a Hair waxing is achieved. 5. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß längenbegrenzte Behaarung, wie Wimpern und Augenbrauenbewachsung, erreicht wird. 5. After some previous claims, characterized in that length-limited hair, such as eyelashes and eyebrow growth, is achieved.   6. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß Mikrokanülen oder Braunülen als Einfachkanüle oder Kanülenbündel zur Haarbewachsung subkutan eingebracht werden.6. According to some previous claims, characterized in that Micro cannulas or Braun cannulas as single cannulas or bundles of cannulas Hair waxing can be introduced subcutaneously. 7. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß ein Multi-Kanülen-Rad zur manuellen oder maschinellen Haarsubstrateinbringung benutzt wird.7. After some previous claims, characterized in that a multi-cannula wheel for manual or machine Hair substrate insertion is used. 8. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß Mikrokanülen als Kanülenbündel mit einer linearen Tackereinbringung benutzt werden, mit 20 bis 1200 subkutanen Haarkanalbildungshüben.8. According to some previous claims, characterized in that Micro cannulas as a cannula bundle with a linear tacker insertion can be used with 20 to 1200 subcutaneous hair channel formation strokes. 9. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß die Kanülen durch Eintauchen befüllt werden.9. According to some previous claims, characterized in that the cannulas are filled by immersion. 10. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß alle medizintechnischen Infusionsgarnituren zum Befüllen benutzt werden.10. According to some previous claims, characterized in that all medical-technical infusion sets are used for filling. 11. Nach einigen vorangegangenen Ansprüchen dadurch gekennzeichnet, daß die zu behaarenden Hautflächen vorher subkutan eingefärbt werden.11. According to some previous claims, characterized in that the skin areas to be haired are dyed beforehand.
DE10005329A 2000-02-08 2000-02-08 Stimulating growth of hair, e.g. on the head, eyebrows or eyelashes, by subcutaneous application of a preparation containing stem cells and/or preformed hair cells Withdrawn DE10005329A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE10005329A DE10005329A1 (en) 2000-02-08 2000-02-08 Stimulating growth of hair, e.g. on the head, eyebrows or eyelashes, by subcutaneous application of a preparation containing stem cells and/or preformed hair cells
PCT/EP2001/001354 WO2001058413A1 (en) 2000-02-08 2001-02-08 Method for stimulating hair growth and kit for carrying out said method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10005329A DE10005329A1 (en) 2000-02-08 2000-02-08 Stimulating growth of hair, e.g. on the head, eyebrows or eyelashes, by subcutaneous application of a preparation containing stem cells and/or preformed hair cells

Publications (1)

Publication Number Publication Date
DE10005329A1 true DE10005329A1 (en) 2001-09-20

Family

ID=7630092

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10005329A Withdrawn DE10005329A1 (en) 2000-02-08 2000-02-08 Stimulating growth of hair, e.g. on the head, eyebrows or eyelashes, by subcutaneous application of a preparation containing stem cells and/or preformed hair cells

Country Status (2)

Country Link
DE (1) DE10005329A1 (en)
WO (1) WO2001058413A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030043928A (en) 2000-08-08 2003-06-02 바이오아미드 인코포레이티드 Scaffolds for tissue engineered hair
MXPA03006714A (en) * 2001-01-29 2005-04-08 Aderans Res Inst Inc Hair follicle neogenesis by injection of follicle progenitor cells.
US20030161815A1 (en) * 2002-02-12 2003-08-28 Intercytex Limited Cell delivery system
CA2505409C (en) 2002-11-14 2017-04-04 Intercytex Limited Cultivation of hair inductive cells
US7597885B2 (en) 2004-03-26 2009-10-06 Aderans Research Institute, Inc. Tissue engineered biomimetic hair follicle graft
AU2012204059B2 (en) * 2005-03-29 2015-01-15 The Trustees Of The University Of Pennsylvania Methods for generating new hair follicles, treating baldness and hair removal
KR20070120559A (en) * 2005-03-29 2007-12-24 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 How to create new hair follicles, how to treat hair loss and how to remove hair
US20070148138A1 (en) 2005-11-22 2007-06-28 Aderans Research Institute, Inc. Hair follicle graft from tissue engineered skin
JP2014500275A (en) 2010-12-06 2014-01-09 フォリカ，インコーポレイテッド Methods for treating baldness and for promoting hair growth
US20140276359A1 (en) * 2013-03-15 2014-09-18 Plum Systems Co. Apparatus and method for tissue rejuvenation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8604360D0 (en) * 1986-02-21 1986-03-26 Univ Dundee Stimulation of hair growth
AU7746091A (en) * 1990-04-17 1991-11-11 Pherin Corporation Methods of tissue implantation
WO1999001034A1 (en) * 1997-07-01 1999-01-14 Cooley Jerry E Method for producing new hair growth
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions

Also Published As

Publication number Publication date
WO2001058413A1 (en) 2001-08-16

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