CY1124590T1 - USES OF BENZIMIDAZOLE DERIVATIVE FOR NOCTERINE ACID ESCAPE - Google Patents
USES OF BENZIMIDAZOLE DERIVATIVE FOR NOCTERINE ACID ESCAPEInfo
- Publication number
- CY1124590T1 CY1124590T1 CY20211100582T CY211100582T CY1124590T1 CY 1124590 T1 CY1124590 T1 CY 1124590T1 CY 20211100582 T CY20211100582 T CY 20211100582T CY 211100582 T CY211100582 T CY 211100582T CY 1124590 T1 CY1124590 T1 CY 1124590T1
- Authority
- CY
- Cyprus
- Prior art keywords
- benzimidazole derivative
- nocterine
- acid
- nocturnal
- acid escape
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με μια χρήση ενώσεων παραγώγων βενζιμιδαζολίου για βελτίωση και θεραπεία της νυκτερινής διαφυγής οξέος (ΝΑΒ). Οι ενώσεις παράγωγα βενζιμιδαζολίου μπορούν με πιο αποτελεσματικό τρόπο να προλάβουν και να θεραπεύσουν ασθένειες που σχετίζονται με γαστρικό οξύ μέσω αποτελεσματικής βελτίωσης και θεραπείας των νυκτερινών συμπτωμάτων νυκτερινής διαφυγής οξέος.The present invention relates to a use of benzimidazole derivative compounds for ameliorating and treating nocturnal acid reflux (NAB). Benzimidazole derivative compounds can more effectively prevent and treat gastric acid-related diseases by effectively improving and treating the nocturnal symptoms of nocturnal acid reflux.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562172680P | 2015-06-08 | 2015-06-08 | |
| PCT/KR2016/006072 WO2016200148A1 (en) | 2015-06-08 | 2016-06-08 | Uses of benzimidazole derivative for nocturnal acid breakthrough |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1124590T1 true CY1124590T1 (en) | 2022-07-22 |
Family
ID=57504150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20211100582T CY1124590T1 (en) | 2015-06-08 | 2021-06-30 | USES OF BENZIMIDAZOLE DERIVATIVE FOR NOCTERINE ACID ESCAPE |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US10512635B2 (en) |
| EP (1) | EP3305291B1 (en) |
| JP (1) | JP6792269B2 (en) |
| KR (3) | KR20160144927A (en) |
| CN (2) | CN108012527A (en) |
| CL (1) | CL2017003133A1 (en) |
| CY (1) | CY1124590T1 (en) |
| DK (1) | DK3305291T3 (en) |
| ES (1) | ES2890481T3 (en) |
| HK (1) | HK1252562A1 (en) |
| HR (1) | HRP20211046T1 (en) |
| HU (1) | HUE056322T2 (en) |
| IL (1) | IL256127B (en) |
| LT (1) | LT3305291T (en) |
| MA (1) | MA41730B1 (en) |
| MX (1) | MX374972B (en) |
| MY (1) | MY197209A (en) |
| PH (1) | PH12017502221A1 (en) |
| PL (1) | PL3305291T3 (en) |
| PT (1) | PT3305291T (en) |
| RS (1) | RS62074B1 (en) |
| RU (1) | RU2672248C1 (en) |
| SG (1) | SG11201710006PA (en) |
| SI (1) | SI3305291T1 (en) |
| SM (1) | SMT202100399T1 (en) |
| TN (1) | TN2017000510A1 (en) |
| WO (1) | WO2016200148A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101960357B1 (en) | 2016-12-26 | 2019-03-20 | 씨제이헬스케어 주식회사 | The novel formulation comprising a benzimidazole derivative |
| KR102262743B1 (en) | 2017-07-07 | 2021-06-09 | 에이치케이이노엔 주식회사 | Composition for injection |
| JOP20190201A1 (en) * | 2018-08-29 | 2020-02-29 | Hk Inno N Corp | Combination to eradicate Helicobacter pylori |
| JP2022520276A (en) | 2019-02-18 | 2022-03-29 | エイチケー イノ．エヌ コーポレーション | Pharmaceutical composition containing a benzimidazole derivative compound |
| UY39094A (en) * | 2020-02-27 | 2021-07-30 | Hk Inno N Corp | PHARMACEUTICAL COMPOSITION INCLUDING BENZIMIDAZOLE DERIVATIVE COMPOUND |
| US10991190B1 (en) | 2020-07-20 | 2021-04-27 | Abbott Laboratories | Digital pass verification systems and methods |
| CN116507318A (en) * | 2020-10-23 | 2023-07-28 | 怡诺安有限公司 | Orally disintegrating tablet containing benzimidazole derivative compound and its preparation method |
| CN118355013A (en) * | 2021-12-08 | 2024-07-16 | 制药基因科学株式会社 | Benzimidazole derivative compounds and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR043063A1 (en) * | 2002-12-13 | 2005-07-13 | Altana Pharma Ag | 6-SUBSTITUTED BENCIMIDAZOLS AND THEIR USE AS INHIBITORS OF GASTRIC SECRETIONS |
| MXPA06002443A (en) * | 2003-09-03 | 2006-08-31 | Agi Therapeutics Ltd | Proton pump inhibitor formulations, and methods of preparing and using such formulations. |
| EP1893197B1 (en) | 2005-06-14 | 2009-09-09 | RaQualia Pharma Inc | Chromane substituted benzimidazole derivatives as acid pump antagonists |
| BRPI0620081B8 (en) | 2005-12-19 | 2021-05-25 | Pfizer | compound and pharmaceutical composition. |
| CA2665226C (en) * | 2006-10-05 | 2014-05-13 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
| WO2008151927A2 (en) * | 2007-06-15 | 2008-12-18 | Nycomed Gmbh | 6-n-substituted benz imidazole derivatives as acid pump antagonists |
| CL2009000547A1 (en) | 2008-03-10 | 2010-05-07 | Takeda Pharmaceuticals Co | Crystalline form of (r) -2 [[[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -1h-benzimidazole, method of preparation; Pharmaceutical composition and its use for the prophylaxis or treatment of peptic ulcer, gastritis, erosive esophagitis, barret's esophagus, functional dyspepsia, gastric cancer. |
| JP5802898B2 (en) * | 2009-07-09 | 2015-11-04 | ラクオリア創薬株式会社 | Acid pump antagonists for treating diseases involving gastrointestinal motility disorders |
| CN102140099A (en) | 2010-02-02 | 2011-08-03 | 山东轩竹医药科技有限公司 | Novel pyridine derivative |
| RU2537140C1 (en) * | 2013-09-17 | 2014-12-27 | Леонид Федосеевич Ляпустин | Method for anti-helicobacter therapy of stomach and duodenum |
-
2016
- 2016-06-08 SI SI201631260T patent/SI3305291T1/en unknown
- 2016-06-08 DK DK16807788.1T patent/DK3305291T3/en active
- 2016-06-08 US US15/580,850 patent/US10512635B2/en active Active
- 2016-06-08 HK HK18111875.7A patent/HK1252562A1/en unknown
- 2016-06-08 EP EP16807788.1A patent/EP3305291B1/en active Active
- 2016-06-08 LT LTEP16807788.1T patent/LT3305291T/en unknown
- 2016-06-08 PT PT168077881T patent/PT3305291T/en unknown
- 2016-06-08 TN TNP/2017/000510A patent/TN2017000510A1/en unknown
- 2016-06-08 MY MYPI2017704650A patent/MY197209A/en unknown
- 2016-06-08 CN CN201680033581.6A patent/CN108012527A/en active Pending
- 2016-06-08 PL PL16807788T patent/PL3305291T3/en unknown
- 2016-06-08 RS RS20210848A patent/RS62074B1/en unknown
- 2016-06-08 SM SM20210399T patent/SMT202100399T1/en unknown
- 2016-06-08 ES ES16807788T patent/ES2890481T3/en active Active
- 2016-06-08 CN CN202410477736.1A patent/CN118557572A/en active Pending
- 2016-06-08 HR HRP20211046TT patent/HRP20211046T1/en unknown
- 2016-06-08 MA MA41730A patent/MA41730B1/en unknown
- 2016-06-08 WO PCT/KR2016/006072 patent/WO2016200148A1/en not_active Ceased
- 2016-06-08 RU RU2017144552A patent/RU2672248C1/en active
- 2016-06-08 JP JP2017563939A patent/JP6792269B2/en active Active
- 2016-06-08 SG SG11201710006PA patent/SG11201710006PA/en unknown
- 2016-06-08 KR KR1020160071275A patent/KR20160144927A/en not_active Ceased
- 2016-06-08 HU HUE16807788A patent/HUE056322T2/en unknown
- 2016-06-08 MX MX2017015926A patent/MX374972B/en active IP Right Grant
-
2017
- 2017-12-05 PH PH12017502221A patent/PH12017502221A1/en unknown
- 2017-12-05 IL IL256127A patent/IL256127B/en active IP Right Grant
- 2017-12-07 CL CL2017003133A patent/CL2017003133A1/en unknown
-
2018
- 2018-03-26 KR KR1020180034581A patent/KR102061052B1/en active Active
-
2019
- 2019-11-07 US US16/676,659 patent/US11033532B2/en active Active
- 2019-12-20 KR KR1020190172242A patent/KR20200002739A/en not_active Withdrawn
-
2021
- 2021-06-30 CY CY20211100582T patent/CY1124590T1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1124590T1 (en) | USES OF BENZIMIDAZOLE DERIVATIVE FOR NOCTERINE ACID ESCAPE | |
| CY1122909T1 (en) | METHODS OF TREATMENT OF EOSINOPHILIC ESEOPHAGITIS BY ADMINISTRATION OF AN IL-4R INHIBITOR | |
| CL2020001752A1 (en) | Derivative of oxy-fluoropiperidine as a kinase inhibitor. | |
| EA201792536A1 (en) | TRIAZOLE AGONISTS APJ RECEPTOR | |
| CY1125247T1 (en) | METHODS OF TREATING DEPRESSION USING OREXIN-2 RECEPTOR ANTAGONISTS | |
| CO2020007156A2 (en) | Derivative of amino-methyl piperidine as kinase inhibitor | |
| ECSP18093777A (en) | DERIVATIVES OF PYRAZOLOPYRIMIDINE AS A KINASE INHIBITOR | |
| CY1126036T1 (en) | DOSAGE FORMS OF SACUBITRIL-VALSARTAN FOR THE THERAPEUTIC TREATMENT OF HEART FAILURE | |
| CL2020001754A1 (en) | Derivative of amino-fluoropiperidine as a kinase inhibitor. | |
| CY1121710T1 (en) | ANGIOPIETIN-BASED INTERVENTIONS FOR THE TREATMENT OF CEREBRAL MALARIA | |
| EA201890308A1 (en) | SUBSTITUTED ASO COMPOUNDS AS IRAK-4 INHIBITORS | |
| EA201691354A1 (en) | THERAPEUTIC INHIBITIVE COMPOUNDS | |
| EA201792205A1 (en) | HETEROCYCLIC COMPOUNDS AS LSD1 INHIBITORS | |
| EA201692418A1 (en) | SUBSTITUTE INDASOLIC COMPOUNDS AS IRAK4 INHIBITORS | |
| EA201691421A1 (en) | HETEROARILES AND THEIR APPLICATION | |
| ECSP17029203A (en) | KINASE INHIBITOR AURORA A | |
| MX2019006893A (en) | Heterocyclic inhibitors of mct4. | |
| EA201891644A1 (en) | ANTIBACTERIAL CONNECTIONS AND THEIR APPLICATION | |
| EA201890694A1 (en) | GROUP OF COMPOUNDS USING FOR THE TREATMENT OR PREVENTION OF HYPERURICEMIA OR Gout | |
| CY1123438T1 (en) | PROCEDURE FOR THE PRODUCTION AND PURIFICATION OF RECOMBINANT LYSOSOMIC ALPHA-MANNOSIDASE | |
| EA201690227A1 (en) | AZAINDOL COMPOUNDS, THEIR PRODUCTION AND METHODS OF THEIR APPLICATION | |
| CL2019002025A1 (en) | Pyrrolotriazine derivatives as a kinase inhibitor. | |
| MX2018001684A (en) | Method of wound healing. | |
| CY1121909T1 (en) | 4-(3-PYRAZOLILAMINO)-BENZIMIDAZOLE DERIVATIVE AS A JAK1 INHIBITOR FOR CANCER INDUCTION | |
| EA201690214A1 (en) | METHOD FOR TREATING HYPERTROPHIC CARDIOMYOPATHY |