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CY1121073T1 - Διαταξεις διασπορας για συσσωματωματα - Google Patents

Διαταξεις διασπορας για συσσωματωματα

Info

Publication number
CY1121073T1
CY1121073T1 CY181100989T CY181100989T CY1121073T1 CY 1121073 T1 CY1121073 T1 CY 1121073T1 CY 181100989 T CY181100989 T CY 181100989T CY 181100989 T CY181100989 T CY 181100989T CY 1121073 T1 CY1121073 T1 CY 1121073T1
Authority
CY
Cyprus
Prior art keywords
vortex
cell
chamber
block
dispersing
Prior art date
Application number
CY181100989T
Other languages
English (en)
Inventor
Guillaume Rigaut
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of CY1121073T1 publication Critical patent/CY1121073T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M43/00—Combinations of bioreactors or fermenters with other apparatus
    • C12M43/02—Bioreactors or fermenters combined with devices for liquid fuel extraction; Biorefineries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Η παρούσα εφεύρεση περιλαμβάνει μία διάταξη διασποράς συνεχούς ροής για την διασπορά κυτταρικών συσσωματωμάτων, περιλαμβάνουσα η διάταξη έναν πρώτο ή ανάντη φραγμό εισόδου και έναν δεύτερο ή κατάντη φραγμό εξόδου, έχοντας έκαστος φραγμός μία τουλάχιστον διαμπερή οπή, όπου δεν υφίσταται κανένα σύνολο δύο οπών σε ευθυγράμμιση. Μεταξύ των δύο φραγμών βρίσκεται ένας θάλαμος στροβιλισμού, κατά τρόπον που, όταν ένα κυτταρικό εναιώρημα διέρχεται, δια μέσου των οπών εισόδου, εντός του θαλάμου και εν συνεχεία εξέρχεται από τον δεύτερο φραγμό, ο στροβιλισμός εντός του θαλάμου να διασπά και να διασπείρει τα κυτταρικά συσσωματώματα. Η διάταξη προαιρετικά μπορεί να έχει περισσότερους των δύο φραγμών και θαλάμων στροβιλισμού και πολλαπλές μονάδες μπορούν να τοποθετηθούν σε σειρά για την αύξηση της ποσότητας στροβιλισμού και του χρόνου που εφαρμόζεται σε έναν όγκο κυττάρων. Η εφεύρεση περιλαμβάνει περαιτέρω μεθόδους χρησιμοποίησης της διάταξης για την διασπορά κυτταρικών συσσωματωμάτων, και μεθόδους καλλιέργειας κυττάρων που χρησιμοποιούν καλλιέργειες σπόρων και διατήρηση των διεσπαρμένων μεμονωμένων κυττάρων.
CY181100989T 2006-10-11 2018-09-25 Διαταξεις διασπορας για συσσωματωματα CY1121073T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85103706P 2006-10-11 2006-10-11
PCT/US2007/080958 WO2008067044A2 (en) 2006-10-11 2007-10-10 Dispersion devices for aggregates

Publications (1)

Publication Number Publication Date
CY1121073T1 true CY1121073T1 (el) 2019-12-11

Family

ID=39468568

Family Applications (1)

Application Number Title Priority Date Filing Date
CY181100989T CY1121073T1 (el) 2006-10-11 2018-09-25 Διαταξεις διασπορας για συσσωματωματα

Country Status (12)

Country Link
US (1) US7658341B2 (el)
EP (2) EP3428267B1 (el)
CY (1) CY1121073T1 (el)
DK (1) DK2076157T3 (el)
ES (1) ES2688284T3 (el)
HU (1) HUE040347T2 (el)
LT (1) LT2076157T (el)
PL (1) PL2076157T3 (el)
PT (1) PT2076157T (el)
SI (1) SI2076157T1 (el)
TR (1) TR201816129T4 (el)
WO (1) WO2008067044A2 (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9631174B2 (en) 2008-04-10 2017-04-25 Georgia Tech Research Corporation Methods and devices for dispersing somatic plant embryos
PT2271200E (pt) * 2008-04-10 2014-09-30 Georgia Tech Res Inst Métodos para dispersar embriões de plantas somáticos
PL2486125T3 (pl) 2009-10-09 2015-08-31 Georgia Tech Res Inst Urządzenie separatora, urządzenie osadzające i system do manipulacji somatycznymi zarodkami roślinnymi
EP2486119B1 (en) * 2009-10-09 2017-04-19 Georgia Tech Research Corporation Method and device for dispersion of assemblies of biological material
US10004189B2 (en) 2009-10-09 2018-06-26 Georgia Tech Research Corporation Separator device, deposition device and system for handling of somatic plant embryos
JP6306708B2 (ja) * 2014-07-22 2018-04-04 株式会社日立ハイテクノロジーズ 細胞分散装置およびそれを用いた自動継代培養システム
CN104195038B (zh) * 2014-09-11 2016-06-15 广州聚能纳米生物科技股份有限公司 同轴线双高压缸均质一体化装置
DE102016202139A1 (de) 2016-02-12 2017-08-17 Hamilton Bonaduz Ag Zellvereinzelungsvorrichtung und Verwendung einer Strömungsformation zur Zellvereinzelungsvorrichtung
CN106976160A (zh) * 2017-02-24 2017-07-25 南通弘亚机械制造有限公司 具有较高均匀性的水泥粉体气力均化装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL48062C (el) * 1938-03-11 1939-10-16
BE623894A (el) 1961-10-20
FI80617C (fi) * 1986-05-09 1990-07-10 Finnpulva Ab Oy Foerfarande och anordning foer foerbaettrande av malningsresultatet i en tryckammarkvarn.
FI84032C (fi) * 1988-11-28 1991-10-10 Finnpulva Ab Oy Foerfarande och anlaeggning foer klassificering av synnerligen finfoerdelat material.
US5356814A (en) * 1992-09-29 1994-10-18 Hoffmann-La Roche Inc. Disaggregation device for cytological specimens
US5598979A (en) * 1995-04-20 1997-02-04 Vortec, Inc. Closed loop gradient force comminuting and dehydrating system
US5968018A (en) * 1996-10-30 1999-10-19 Cohesion Corporation Cell separation device and in-line orifice mixer system
US6786437B2 (en) * 1998-06-19 2004-09-07 Harris J. Ribardi Closed loop cyclonic mill, and method and apparatus for drying and fiberizing material
US6138931A (en) 1999-07-27 2000-10-31 Xerox Corporation Apparatus and method for grinding particulate material
US6623959B2 (en) * 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
US6739531B2 (en) * 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses
TWM249953U (en) * 2003-03-19 2004-11-11 Yeu Ming Tai Chemical Ind Co L Processing device for nano-material

Also Published As

Publication number Publication date
TR201816129T4 (tr) 2018-11-21
LT2076157T (lt) 2018-11-12
DK2076157T3 (en) 2018-11-26
PL2076157T3 (pl) 2018-12-31
EP3428267A1 (en) 2019-01-16
EP2076157B1 (en) 2018-08-01
US7658341B2 (en) 2010-02-09
EP2076157A4 (en) 2012-07-04
WO2008067044A2 (en) 2008-06-05
US20080108137A1 (en) 2008-05-08
PT2076157T (pt) 2018-11-16
EP2076157A2 (en) 2009-07-08
EP3428267B1 (en) 2023-11-29
WO2008067044A3 (en) 2008-12-04
ES2688284T3 (es) 2018-10-31
SI2076157T1 (sl) 2018-12-31
HUE040347T2 (hu) 2019-03-28

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