CY1118360T1 - Παρατεταμενης διαρκειας τοπικη αναισθητικη συνθεση η οποια περιεχει saib - Google Patents
Παρατεταμενης διαρκειας τοπικη αναισθητικη συνθεση η οποια περιεχει saibInfo
- Publication number
- CY1118360T1 CY1118360T1 CY20161101218T CY161101218T CY1118360T1 CY 1118360 T1 CY1118360 T1 CY 1118360T1 CY 20161101218 T CY20161101218 T CY 20161101218T CY 161101218 T CY161101218 T CY 161101218T CY 1118360 T1 CY1118360 T1 CY 1118360T1
- Authority
- CY
- Cyprus
- Prior art keywords
- long
- local anesthetic
- anesthetic composition
- term local
- saib
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000003589 local anesthetic agent Substances 0.000 title 1
- 230000007774 longterm Effects 0.000 title 1
- UVGUPMLLGBCFEJ-SWTLDUCYSA-N sucrose acetate isobutyrate Chemical compound CC(C)C(=O)O[C@H]1[C@H](OC(=O)C(C)C)[C@@H](COC(=O)C(C)C)O[C@@]1(COC(C)=O)O[C@@H]1[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@@H](COC(C)=O)O1 UVGUPMLLGBCFEJ-SWTLDUCYSA-N 0.000 title 1
- 235000010983 sucrose acetate isobutyrate Nutrition 0.000 title 1
- 206010002091 Anaesthesia Diseases 0.000 abstract 1
- 230000037005 anaesthesia Effects 0.000 abstract 1
- 238000001949 anaesthesia Methods 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Selective Calling Equipment (AREA)
- Optical Communication System (AREA)
- Amplifiers (AREA)
- Detergent Compositions (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με υγρές συνθέσεις για την παροχή παρατεταμένης τοπικής αναισθησίας μετά τη χορήγηση σε ένα υποκείμενο, οι οποίες συνθέσεις περιλαμβάνουν ένα αναισθητικό, έναν φαρμακευτικά αποδεκτό μη πολυμερικό φορέα και έναν διαλύτη για τον εν λόγω φορέα.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61079704P | 2004-09-17 | 2004-09-17 | |
| US69139505P | 2005-06-17 | 2005-06-17 | |
| EP20110187311 EP2415484B1 (en) | 2004-09-17 | 2005-09-15 | Sustained local anesthetic composition containing SAIB |
| EP05812735A EP1809329B1 (en) | 2004-09-17 | 2005-09-15 | Sustained local anesthetic composition containing saib |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1118360T1 true CY1118360T1 (el) | 2017-06-28 |
Family
ID=35949130
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100253T CY1112625T1 (el) | 2004-09-17 | 2012-03-12 | Παρατεταμενης διαρκειας τοπικη αναισθητικη συνθεση η οποια περιεχει sαιβ |
| CY20161101218T CY1118360T1 (el) | 2004-09-17 | 2016-11-24 | Παρατεταμενης διαρκειας τοπικη αναισθητικη συνθεση η οποια περιεχει saib |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100253T CY1112625T1 (el) | 2004-09-17 | 2012-03-12 | Παρατεταμενης διαρκειας τοπικη αναισθητικη συνθεση η οποια περιεχει sαιβ |
Country Status (25)
| Country | Link |
|---|---|
| US (9) | US8753665B2 (el) |
| EP (4) | EP1809329B1 (el) |
| JP (2) | JP5285275B2 (el) |
| KR (2) | KR101492361B1 (el) |
| AT (1) | ATE537844T1 (el) |
| AU (1) | AU2005287175B2 (el) |
| BR (1) | BRPI0515372B8 (el) |
| CA (1) | CA2581287C (el) |
| CY (2) | CY1112625T1 (el) |
| DK (3) | DK1809329T3 (el) |
| EA (2) | EA014852B1 (el) |
| ES (3) | ES2496765T3 (el) |
| GE (1) | GEP20094831B (el) |
| HR (1) | HRP20120254T1 (el) |
| HU (1) | HUE032040T2 (el) |
| IL (1) | IL181474A (el) |
| LT (1) | LT2767292T (el) |
| MX (1) | MX2007002962A (el) |
| NO (1) | NO342596B1 (el) |
| NZ (1) | NZ553369A (el) |
| PL (2) | PL2415484T3 (el) |
| PT (3) | PT2415484E (el) |
| RS (1) | RS52198B (el) |
| SI (2) | SI2767292T1 (el) |
| WO (1) | WO2006033948A2 (el) |
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| US7833543B2 (en) * | 1995-06-07 | 2010-11-16 | Durect Corporation | High viscosity liquid controlled delivery system and medical or surgical device |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| SI2767292T1 (sl) * | 2004-09-17 | 2017-01-31 | Durect Corporation | Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem |
| WO2006039336A2 (en) * | 2004-10-01 | 2006-04-13 | Ramscor, Inc. | Conveniently implantable sustained release drug compositions |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP2117521B1 (en) | 2006-11-03 | 2012-06-27 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| PL3085363T3 (pl) * | 2007-03-28 | 2019-08-30 | Innocoll Pharmaceuticals Limited | Urządzenie dostarczające lek dla zapewnienia miejscowej analgezji, miejscowego znieczulenia lub blokady nerwowej |
| WO2009100222A1 (en) * | 2008-02-08 | 2009-08-13 | Qps Llc | Non-polymeric compositions for controlled drug delivery |
| US20100143437A1 (en) * | 2008-12-09 | 2010-06-10 | Morris Edward J | Implantable analgesic |
| US9045600B2 (en) | 2009-05-13 | 2015-06-02 | Keraplast Technologies, Ltd. | Biopolymer materials |
| MX347014B (es) * | 2010-11-24 | 2017-04-07 | Durect Corp | Composición para administración de fármaco biodegradable. |
| EP2849724B8 (en) * | 2012-05-16 | 2018-08-29 | Orexa B.V. | Means to facilitate food intake and food retention |
| MX352907B (es) * | 2013-03-15 | 2017-12-13 | Heron Therapeutics Inc | Composiciones de un poliortoéster y un solvente aprótico. |
| WO2014187962A1 (en) * | 2013-05-24 | 2014-11-27 | Danmarks Tekniske Universitet | Gel formulations for guiding radiotherapy |
| CN105764491A (zh) | 2013-12-09 | 2016-07-13 | 度瑞公司 | 药物活性剂复合物、聚合物复合物,以及包括其的组合物和方法 |
| WO2015123734A1 (en) * | 2014-02-21 | 2015-08-27 | The University Of Sydney | Liquid carrier materials |
| DK3134068T3 (da) | 2014-04-21 | 2021-10-04 | Heron Therapeutics Inc | Langtidsvirkende polymerafgivelsessystemer |
| WO2018048460A1 (en) | 2014-04-21 | 2018-03-15 | Heron Therapeutics, Inc. | A pharmaceutical composition comprising a delivery system, an amide-type local anesthetic, and meloxicam |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| KR20170025011A (ko) | 2015-08-27 | 2017-03-08 | 고려대학교 산학협력단 | 통증완화약물의 지속성 방출을 위한 약학적 조성물 및 그 투여를 위한 투여 장치 |
| JP2019514976A (ja) * | 2016-05-05 | 2019-06-06 | リクイディア・テクノロジーズ・インコーポレーテッド | 負荷と放出が正確に制御された術後疼痛用粒子 |
| US10682340B2 (en) | 2016-06-30 | 2020-06-16 | Durect Corporation | Depot formulations |
| EP3478285A4 (en) * | 2016-06-30 | 2020-07-22 | Durect Corporation | DEPOSIT FORMULATIONS |
| EP3558279A4 (en) * | 2016-12-26 | 2020-12-02 | Cellix Bio Private Limited | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC PAIN |
| EA039449B1 (ru) * | 2017-03-27 | 2022-01-28 | Фрути Холдингс Лимитед | Слаборастворимый комплекс или его сольват, фармацевтическая композиция и их применение |
| CN111432807A (zh) | 2017-10-06 | 2020-07-17 | 铸造疗法股份有限公司 | 用于控制释放治疗剂的可植入贮库 |
| RU2674025C1 (ru) * | 2017-10-25 | 2018-12-04 | Общество с ограниченной ответственностью "Научно-производственная фирма "ЭЛЕСТ" (ООО "НПФ "ЭЛЕСТ") | Лекарственное средство на основе порфиринового фотосенсибилизатора копропорфирина для лечения рака кожи методом фотодинамической терапии |
| WO2019136490A1 (en) | 2018-01-08 | 2019-07-11 | Foundry Therapeutics, Inc. | Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents |
| EP3793536A1 (en) | 2018-05-12 | 2021-03-24 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| EP3843710A1 (en) | 2018-08-28 | 2021-07-07 | Foundry Therapeutics, Inc. | Polymer implants |
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| US20230080593A1 (en) | 2020-01-10 | 2023-03-16 | Pacira Pharmaceuticals, Inc. | Treatment of pain by subarachnoid administration of sustained-release liposomal anesthetic compositions |
| KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
| EP4110293A4 (en) * | 2020-02-25 | 2024-07-10 | The University of North Carolina at Chapel Hill | EUTECTIC-BASED ANESTHESIC COMPOSITIONS AND CORRESPONDING APPLICATIONS |
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