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CY1118259T1 - Μεθοδος αναλυσης μεθυλιωσης - Google Patents

Μεθοδος αναλυσης μεθυλιωσης

Info

Publication number
CY1118259T1
CY1118259T1 CY20161100391T CY161100391T CY1118259T1 CY 1118259 T1 CY1118259 T1 CY 1118259T1 CY 20161100391 T CY20161100391 T CY 20161100391T CY 161100391 T CY161100391 T CY 161100391T CY 1118259 T1 CY1118259 T1 CY 1118259T1
Authority
CY
Cyprus
Prior art keywords
methylisis
analysis method
compositions
aspects
methods
Prior art date
Application number
CY20161100391T
Other languages
English (en)
Inventor
Theo Devos
Cathy Lofton-Day
Andrew Sledziewski
Fabian Model
Michael Krouse
Mathias Schuster
Jürgen Distler
Reimo Tetzner
Jesse Ho
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Publication of CY1118259T1 publication Critical patent/CY1118259T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Πτυχές της εφεύρεσης σχετίζονται με συνθέσεις και μεθόδους για την παροχή DNA για ανάλυση μεθυλίωσης που είναι ιδιαιτέρως κατάλληλη για εφαρμογή σε εργαστήρια αναφοράς. Περεταίρω 5 πτυχές της ανάπτυξης σχετίζονται με συνθέσεις και μεθόδους για την υψηλής ειδικότητας και ευαισθησίας ανάλυση μεθυλίωσης του γονιδίου SEPT9, επίσης ιδιαιτέρως κατάλληλη για εφαρμογή σε εργαστήρια αναφοράς.
CY20161100391T 2007-06-08 2016-05-10 Μεθοδος αναλυσης μεθυλιωσης CY1118259T1 (el)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP07109907 2007-06-08
EP07110409 2007-06-15
EP07113516 2007-07-31
EP07114659 2007-08-21
EP07114863 2007-08-23
EP08150552 2008-01-23
EP08151442 2008-02-14
EP12164321.7A EP2479289B1 (en) 2007-06-08 2008-06-06 Method for methylation analysis
EP08789067A EP2152902A2 (en) 2007-06-08 2008-06-06 Method for methylation analysis

Publications (1)

Publication Number Publication Date
CY1118259T1 true CY1118259T1 (el) 2017-06-28

Family

ID=40094240

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100391T CY1118259T1 (el) 2007-06-08 2016-05-10 Μεθοδος αναλυσης μεθυλιωσης

Country Status (11)

Country Link
US (1) US8623599B2 (el)
EP (3) EP3101141B1 (el)
CY (1) CY1118259T1 (el)
DK (2) DK2479289T3 (el)
ES (2) ES2570828T3 (el)
HR (2) HRP20160425T1 (el)
HU (1) HUE028727T2 (el)
LT (1) LT3101141T (el)
PL (1) PL2479289T3 (el)
SI (2) SI3101141T1 (el)
WO (1) WO2008149237A2 (el)

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WO2011146629A2 (en) 2010-05-19 2011-11-24 Qiagen Gaithersburg Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
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EP3124605A1 (en) * 2012-03-15 2017-02-01 New England Biolabs, Inc. Methods and compositions for discrimination between cytosine and modifications thereof, and for methylome analysis
EP2746403A1 (de) 2012-12-21 2014-06-25 Life Science Inkubator GmbH & Co. KG Verfahren zur Bestimmung des DNA-Methylierungsgrades
WO2014149356A1 (en) * 2013-03-15 2014-09-25 Abbott Molecular Inc. Detection of bisulfite converted nucleotide sequences
PL4026917T3 (pl) 2014-04-14 2024-04-08 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Metoda i zestaw do określania śmierci komórek lub tkanek albo tkankowego lub komórkowego pochodzenia dna za pomocą analizy metylacji dna
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
ES2724367T3 (es) * 2014-12-19 2019-09-10 Epigenomics Ag Métodos para detectar la metilación de CpG y para el diagnóstico del cáncer
EP3274440A4 (en) 2015-03-27 2019-03-06 Exact Sciences Corporation Detecting esophageal disorders
CA3233310A1 (en) * 2015-10-30 2017-05-04 Exact Sciences Development Company, Llc Multiplex amplification detection assay and isolation and detection of dna from plasma
WO2017091156A1 (en) * 2015-11-27 2017-06-01 Agency For Science, Technology And Research Determination of nucleic acid methylation
CN105506133A (zh) * 2016-01-15 2016-04-20 武汉艾米森生命科技有限公司 用于检测sept9基因甲基化的组合物、试剂盒及方法
KR102436270B1 (ko) 2016-05-05 2022-08-25 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 폐 종양의 검출
CA3049459A1 (en) 2017-01-27 2018-08-02 Exact Sciences Development Company, Llc Detection of colon neoplasia by analysis of methylated dna
CN107164524A (zh) * 2017-06-27 2017-09-15 深圳市优圣康生物科技有限公司 用于基因甲基化检测的引物和探针、采样方法、试剂盒
WO2019012544A1 (en) 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. STRATEGY FOR DOUBLE PROBE DROPLETS FOR SPECIFIC DETECTION OF CIRCULATING DNA MOLECULES SPECIFIC TO A TISSUE
WO2019012542A1 (en) * 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. DETECTION OF SPECIFIC DNA FROM A FABRIC
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
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CN110283913A (zh) * 2019-07-21 2019-09-27 广州奥百阕谱生物科技有限公司 Rassf1a基因甲基化状态检测试剂盒及其应用
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Also Published As

Publication number Publication date
WO2008149237A3 (en) 2009-06-04
WO2008149237A2 (en) 2008-12-11
HRP20160425T1 (hr) 2016-08-12
EP2152902A2 (en) 2010-02-17
EP2479289A2 (en) 2012-07-25
SI2479289T1 (sl) 2016-10-28
LT3101141T (lt) 2020-03-10
HK1172656A1 (en) 2013-04-26
ES2769841T3 (es) 2020-06-29
EP3101141B1 (en) 2019-10-16
US20110009277A1 (en) 2011-01-13
DK2479289T3 (en) 2016-05-02
EP3101141A2 (en) 2016-12-07
SI3101141T1 (sl) 2020-03-31
PL2479289T3 (pl) 2016-10-31
HUE028727T2 (en) 2017-01-30
DK3101141T3 (da) 2020-02-03
EP3101141A3 (en) 2017-01-11
ES2570828T3 (es) 2016-05-20
HRP20200059T1 (hr) 2020-04-03
US8623599B2 (en) 2014-01-07
EP2479289A3 (en) 2013-06-19
EP2479289B1 (en) 2016-04-06

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