CY1117330T1 - Βενζοδιοξινυλ υποκατεστημενα παραγωγα ινδαζολιου - Google Patents
Βενζοδιοξινυλ υποκατεστημενα παραγωγα ινδαζολιουInfo
- Publication number
- CY1117330T1 CY1117330T1 CY20161100092T CY161100092T CY1117330T1 CY 1117330 T1 CY1117330 T1 CY 1117330T1 CY 20161100092 T CY20161100092 T CY 20161100092T CY 161100092 T CY161100092 T CY 161100092T CY 1117330 T1 CY1117330 T1 CY 1117330T1
- Authority
- CY
- Cyprus
- Prior art keywords
- derivatives
- indazolium
- benzodioxinyl
- substituted
- benzodioxinyl substituted
- Prior art date
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 125000000928 benzodioxinyl group Chemical group O1C(=COC2=C1C=CC=C2)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract
Μια ένωση του τύπου la: (la) Η παρούσα εφεύρεση αφορά νέα ινδαζολυλ παράγωγα, φαρμακευτικές συνθέσεις που περιέχουν τέτοια παράγωγα, διαδικασίες για την παρασκευή τέτοιων νέων παραγώγων και τη χρήση τέτοιων παραγώγων ως φαρμάκων.
Applications Claiming Priority (4)
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| US5461608P | 2008-05-20 | 2008-05-20 | |
| US8031208P | 2008-07-14 | 2008-07-14 | |
| US14477609P | 2009-01-15 | 2009-01-15 | |
| EP09750866.7A EP2291369B1 (en) | 2008-05-20 | 2009-05-20 | Benzodioxinyl substituted indazole derivatives |
Publications (1)
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|---|---|
| CY1117330T1 true CY1117330T1 (el) | 2017-04-26 |
Family
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| WO2016124722A1 (en) * | 2015-02-06 | 2016-08-11 | Astrazeneca Ab | A process for the preparation of 3-5-{[(1r,2s)-2-[(2,2-difluoropropanyl)amino]-1 -(2,3-dihydro-1,4-benzodioxin-6-yl]propyl]oxy}-1h-indazol-1-yl)-n-[(3r)-tetrahydrofuran-3-yl] benzamide |
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