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CY1112477T1 - Φαρμακευτικο παρασκευασμα που εχει εξαιρετικh φωτοσταθεροτητα - Google Patents

Φαρμακευτικο παρασκευασμα που εχει εξαιρετικh φωτοσταθεροτητα

Info

Publication number
CY1112477T1
CY1112477T1 CY20121100247T CY121100247T CY1112477T1 CY 1112477 T1 CY1112477 T1 CY 1112477T1 CY 20121100247 T CY20121100247 T CY 20121100247T CY 121100247 T CY121100247 T CY 121100247T CY 1112477 T1 CY1112477 T1 CY 1112477T1
Authority
CY
Cyprus
Prior art keywords
pharmaceutical preparation
pitavastatin
light stability
extremely light
hmg
Prior art date
Application number
CY20121100247T
Other languages
English (en)
Inventor
Masato Kozaki
Yoshio Tanizawa
Hiroyuki Kawashima
Original Assignee
Kowa Company, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Company, Ltd. filed Critical Kowa Company, Ltd.
Publication of CY1112477T1 publication Critical patent/CY1112477T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά σε φαρμακευτικό παρασκεύασμα υψηλής φωτοσταθερότητας που περιέχει πιταβαστατίνη, που είναι ένας αναστολέας αναγωγάσης ΗΜG-CoA, άλας πιταβαστατίνης ή εστέρα πιταβαστατίνης. Το φαρμακευτικό παρασκεύασμα περιέχει ένωση πιταβαστατίνης, οξείδιο τιτανίου και ένα χρωματιστικό που έχει μέγιστη απορρόφηση μήκους κύματος 400 nm έως 500 nm.
CY20121100247T 2005-10-31 2012-03-09 Φαρμακευτικο παρασκευασμα που εχει εξαιρετικh φωτοσταθεροτητα CY1112477T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005316758 2005-10-31
EP06822589A EP1944029B1 (en) 2005-10-31 2006-10-30 Pharmaceutical preparation having excellent photostability

Publications (1)

Publication Number Publication Date
CY1112477T1 true CY1112477T1 (el) 2015-12-09

Family

ID=38005744

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100247T CY1112477T1 (el) 2005-10-31 2012-03-09 Φαρμακευτικο παρασκευασμα που εχει εξαιρετικh φωτοσταθεροτητα

Country Status (23)

Country Link
US (1) US20090041843A1 (el)
EP (1) EP1944029B1 (el)
JP (3) JP5166876B2 (el)
KR (1) KR101409087B1 (el)
CN (1) CN101300010B (el)
AT (1) ATE537827T1 (el)
AU (1) AU2006309826B2 (el)
CA (1) CA2626309A1 (el)
CY (1) CY1112477T1 (el)
DK (1) DK1944029T3 (el)
EA (1) EA016713B1 (el)
ES (1) ES2375643T3 (el)
IL (1) IL190346A (el)
NO (1) NO20081526L (el)
NZ (1) NZ566872A (el)
PL (1) PL1944029T3 (el)
PT (1) PT1944029E (el)
SG (1) SG196789A1 (el)
SI (1) SI1944029T1 (el)
TW (1) TWI422375B (el)
UA (1) UA92920C2 (el)
WO (1) WO2007052592A1 (el)
ZA (1) ZA200803655B (el)

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JP5809467B2 (ja) * 2011-07-12 2015-11-11 エルメッド エーザイ株式会社 ピタバスタチン含有組成物及びその製造方法
JP5844573B2 (ja) * 2011-08-10 2016-01-20 共和薬品工業株式会社 ピタバスタチンを含有する錠剤
JP5844574B2 (ja) * 2011-08-10 2016-01-20 共和薬品工業株式会社 ピタバスタチンを含有する安定化された薬物組成物
TWI636783B (zh) * 2012-04-18 2018-10-01 友霖生技醫藥股份有限公司 含匹伐他汀（ｐｉｔａｖａｓｔａｔｉｎ）穩定配方的醫藥組合物
EP3269362A1 (en) 2012-08-08 2018-01-17 KOWA Co., Ltd. Pharmaceutical composition comprising pitavastatine
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JP6150703B2 (ja) * 2013-10-08 2017-06-21 ダイト株式会社 ピタバスタチンカルシウム塩の分解抑制方法
JP6243265B2 (ja) * 2014-03-20 2017-12-06 日医工株式会社 ロスバスタチン含有医薬製剤
JP6433400B2 (ja) * 2014-09-30 2018-12-05 株式会社三和化学研究所 ＨＭＧ−ＣｏＡレダクターゼ阻害薬を含有する医薬製剤
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JP7166754B2 (ja) 2017-11-22 2022-11-08 沢井製薬株式会社 ダサチニブ無水物含有製剤
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KR102849723B1 (ko) 2018-07-30 2025-08-22 다이이찌 산쿄 가부시키가이샤 안정화제를 함유하는 의약품의 고형 제제
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Also Published As

Publication number Publication date
SI1944029T1 (sl) 2012-03-30
PT1944029E (pt) 2012-02-09
SG196789A1 (en) 2014-02-13
EP1944029B1 (en) 2011-12-21
DK1944029T3 (da) 2012-01-23
JP2012246325A (ja) 2012-12-13
NZ566872A (en) 2010-12-24
CA2626309A1 (en) 2007-05-10
EA016713B1 (ru) 2012-07-30
AU2006309826A1 (en) 2007-05-10
WO2007052592A1 (ja) 2007-05-10
ATE537827T1 (de) 2012-01-15
EP1944029A1 (en) 2008-07-16
CN101300010A (zh) 2008-11-05
TWI422375B (zh) 2014-01-11
HK1124772A1 (en) 2009-07-24
EP1944029A4 (en) 2011-01-12
ES2375643T3 (es) 2012-03-02
NO20081526L (no) 2008-07-29
ZA200803655B (en) 2009-10-28
US20090041843A1 (en) 2009-02-12
JP2013014610A (ja) 2013-01-24
TW200800191A (en) 2008-01-01
CN101300010B (zh) 2012-06-06
KR20080058449A (ko) 2008-06-25
JP5166876B2 (ja) 2013-03-21
JPWO2007052592A1 (ja) 2009-04-30
JP5677391B2 (ja) 2015-02-25
IL190346A0 (en) 2009-09-22
IL190346A (en) 2013-06-27
EA200800993A1 (ru) 2008-08-29
PL1944029T3 (pl) 2012-05-31
KR101409087B1 (ko) 2014-06-17
AU2006309826B2 (en) 2012-01-19
UA92920C2 (ru) 2010-12-27

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