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CY1112469T1 - Μια il-2 μουτεϊνη για θεραπεια ή για προφυλαξη απο ενα αυτοανοσο νοσημα - Google Patents

Μια il-2 μουτεϊνη για θεραπεια ή για προφυλαξη απο ενα αυτοανοσο νοσημα

Info

Publication number
CY1112469T1
CY1112469T1 CY20121100236T CY121100236T CY1112469T1 CY 1112469 T1 CY1112469 T1 CY 1112469T1 CY 20121100236 T CY20121100236 T CY 20121100236T CY 121100236 T CY121100236 T CY 121100236T CY 1112469 T1 CY1112469 T1 CY 1112469T1
Authority
CY
Cyprus
Prior art keywords
treatment
mutein
protection
automatic disease
disease
Prior art date
Application number
CY20121100236T
Other languages
English (en)
Inventor
Daniela Paulsen
Nina Brunner
Dorothy Bray
Original Assignee
Aicuris Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41152787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112469(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aicuris Gmbh & Co. Kg filed Critical Aicuris Gmbh & Co. Kg
Publication of CY1112469T1 publication Critical patent/CY1112469T1/el

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    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

Η παρούσα εφεύρεση αφορά ένα μέσο για θεραπεία και/ή για προφύλαξη από ένα αυτοάνοσο νόσημα, ένα μέσο για τη δημιουργία ρυθμιστικών Τ-κυττάρων (ΤReg) σε έναν ζώντα οργανισμό, καθώς και διάφορες μεθόδους, στις οποίες χρησιμοποιούνται τα σύμφωνα με την εφεύρεση μέσα.
CY20121100236T 2008-05-08 2012-03-08 Μια il-2 μουτεϊνη για θεραπεια ή για προφυλαξη απο ενα αυτοανοσο νοσημα CY1112469T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008023820A DE102008023820A1 (de) 2008-05-08 2008-05-08 Mittel zur Behandlung und/oder Prophylaxe einer Autoimmunerkrankung und zur Bildung von Regulatorischen T-Zellen
EP09741834A EP2288372B1 (de) 2008-05-08 2009-04-28 Ein il-2 mutein zur behandlung oder prophylaxe einer autoimmunerkrankung

Publications (1)

Publication Number Publication Date
CY1112469T1 true CY1112469T1 (el) 2015-12-09

Family

ID=41152787

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100236T CY1112469T1 (el) 2008-05-08 2012-03-08 Μια il-2 μουτεϊνη για θεραπεια ή για προφυλαξη απο ενα αυτοανοσο νοσημα

Country Status (28)

Country Link
US (4) US20110150826A1 (el)
EP (1) EP2288372B1 (el)
JP (2) JP5651583B2 (el)
KR (3) KR20160092048A (el)
CN (2) CN110935025A (el)
AR (1) AR071756A1 (el)
AT (1) ATE544465T1 (el)
AU (1) AU2009244039B2 (el)
BR (1) BRPI0912411B8 (el)
CA (1) CA2723761C (el)
CL (1) CL2009001099A1 (el)
CY (1) CY1112469T1 (el)
DE (1) DE102008023820A1 (el)
DK (1) DK2288372T3 (el)
ES (1) ES2378957T3 (el)
HR (1) HRP20120296T1 (el)
IL (3) IL209128A (el)
MX (1) MX2010012214A (el)
PE (1) PE20091967A1 (el)
PL (1) PL2288372T3 (el)
PT (1) PT2288372E (el)
RU (1) RU2531936C2 (el)
SI (1) SI2288372T1 (el)
TW (1) TWI510622B (el)
UA (1) UA102099C2 (el)
UY (1) UY31816A (el)
WO (1) WO2009135615A2 (el)
ZA (1) ZA201008129B (el)

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DE102008023820A1 (de) 2008-05-08 2009-11-12 Aicuris Gmbh & Co. Kg Mittel zur Behandlung und/oder Prophylaxe einer Autoimmunerkrankung und zur Bildung von Regulatorischen T-Zellen
CA2749539C (en) 2009-01-21 2022-07-19 Amgen Inc. Compositions and methods comprising interleukin-2 mutants for treating inflammatory and autoimmune diseases
WO2011006029A1 (en) 2009-07-10 2011-01-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Artificial cell constructs for inducing immunological tolerance
US11090363B2 (en) 2009-07-10 2021-08-17 University of Pittsburgh—of the Commonwealth System of Higher Education Vasoactive intestinal peptide release from microparticles
CU23734A1 (es) * 2009-11-27 2011-11-15 Centro Inmunologia Molecular Polipéptidos inmunomoduladores derivados de la il-2 con actividad antagonista de esta citocina útiles en la terapia del cáncer y enfermedades infecciosas crónicas
US9018006B2 (en) * 2010-07-23 2015-04-28 The University Of Toledo Stable Tregs and related materials and methods
CU23923B1 (es) * 2010-11-12 2013-07-31 Ct De Inmunología Molecular Polipéptidos derivados de la il-2 con actividad agonista
KR102220006B1 (ko) 2011-03-11 2021-02-24 아시스땅스 퍼블리끄-오삐또 드 빠리 자가면역 - 관련 또는 염증성 장애를 치료하기 위한 저용량 il­2 의 용도
US9669071B2 (en) 2011-03-11 2017-06-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for stimulating T lymphocytes with IL-2
US20140044675A1 (en) 2012-08-10 2014-02-13 Roche Glycart Ag Interleukin-2 fusion proteins and uses thereof
BR112015013557B1 (pt) 2012-12-11 2021-12-14 Albert Einstein College Of Medicine Sistema, método, método para determinar o efeito de um resíduo de aminoácido predeterminado de uma primeira proteína sobre a ligação da primeira proteína a uma segunda proteína e polipeptídeo pd-l1 mutante
EA201992609A1 (ru) 2014-02-06 2020-03-04 Ф.Хоффманн-Ля Рош Аг Слитые белки, содержащие интерлейкин-2, и их применения
CN113234138A (zh) 2014-08-11 2021-08-10 德里尼亚公司 选择性地活化调节性t细胞用于治疗自身免疫病的修饰的il-2变体
IL304950A (en) 2015-04-10 2023-10-01 Amgen Inc Interleukin for the expansion of myotonic control T-2 cells
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