CY1108503T1 - Dna το οποιο κωδικοποιει τον υποδοχεα snorf25 - Google Patents
Dna το οποιο κωδικοποιει τον υποδοχεα snorf25Info
- Publication number
- CY1108503T1 CY1108503T1 CY20081101291T CY081101291T CY1108503T1 CY 1108503 T1 CY1108503 T1 CY 1108503T1 CY 20081101291 T CY20081101291 T CY 20081101291T CY 081101291 T CY081101291 T CY 081101291T CY 1108503 T1 CY1108503 T1 CY 1108503T1
- Authority
- CY
- Cyprus
- Prior art keywords
- mammalian snorf25
- snorf25 receptors
- receptors
- nucleic acid
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 239000000556 agonist Substances 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 108020000948 Antisense Oligonucleotides Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 230000005856 abnormality Effects 0.000 abstract 1
- 239000000074 antisense oligonucleotide Substances 0.000 abstract 1
- 238000012230 antisense oligonucleotides Methods 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
Abstract
Αυτή η ευρεσιτεχνία παρέχει τα απομονωμένα νουκλεϊκά οξέα που κωδικοποιούν τους υποδοχείς SNORF25 του τύπου των θηλαστικών, τους καθαρισμένους υποδοχείς SNORF25 του τύπου των θηλαστικών, τους φορείς που περιλαμβάνουν το νουκλεϊκό οξύ που κωδικοποιεί τους υποδοχείς SNORF25 του τύπου των θηλαστικών, τα κύτταρα που περιλαμβάνουν τέτοιους φορείς, τα αντισώματα που απευθύνονται στους υποδοχείς SNORF25 των θηλαστικών, στους ανιχνευτές των νουκλεϊκών οξέων που είναι χρήσιμοι για την ανίχνευση του νουκλεϊκού οξέος που κωδικοποιεί τους υποδοχείς SNORF25 του τύπου των θηλαστικών, τα αντιαγγελιαφόρα ολιγονουκλεοτίδια συμπληρωματικά με τις μοναδικές αλληλουχίες του νουκλεϊκού οξέος που κωδικοποιούν τους υποδοχείς SNORF25 του τύπου των θηλαστικών, τα διαγονιδιακά μη ανθρώπινα ζώα που εκφράζουν το DNA που κωδικοποιεί τους φυσιολογικούς ή τους μεταλλακτούς υποδοχείς SNORF25 του τύπου των θηλαστικών, τις μεθόδους θεραπείας μίας ανωμαλίας που συνδέεται με την ενεργότητα των υποδοχέων SNORF25 του τύπου των θηλαστικών, καθώς και τις μεθόδους προσδιορισμού των ενώσεων προς τους υποδοχείς SNORF25 του τύπου των θηλαστικών, τις μεθόδους ταυτοποίησης των αγωνιστών και ανταγωνιστών των υποδοχέων SNORF25 του τύπου των θηλαστικών και των αγωνιστών και ανταγωνιστών που ταυτοποιήθηκαν κατ' αυτόν τον τρόπο.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25537699A | 1999-02-22 | 1999-02-22 | |
| US09/387,699 US6221660B1 (en) | 1999-02-22 | 1999-08-13 | DNA encoding SNORF25 receptor |
| EP00908748A EP1075493B1 (en) | 1999-02-22 | 2000-02-22 | Dna encoding snorf25 receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108503T1 true CY1108503T1 (el) | 2014-04-09 |
Family
ID=26944658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081101291T CY1108503T1 (el) | 1999-02-22 | 2008-11-12 | Dna το οποιο κωδικοποιει τον υποδοχεα snorf25 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6221660B1 (el) |
| EP (1) | EP1075493B1 (el) |
| JP (2) | JP2002539772A (el) |
| AT (1) | ATE405589T1 (el) |
| AU (1) | AU777247B2 (el) |
| CA (1) | CA2362906A1 (el) |
| CY (1) | CY1108503T1 (el) |
| DE (1) | DE60039948D1 (el) |
| DK (1) | DK1075493T3 (el) |
| ES (1) | ES2312333T3 (el) |
| PT (1) | PT1075493E (el) |
| WO (1) | WO2000050562A2 (el) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE42190E1 (en) | 1998-11-20 | 2011-03-01 | Arena Pharmaceuticals, Inc. | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors |
| ES2308759T3 (es) * | 1998-11-20 | 2008-12-01 | Arena Pharmaceuticals, Inc. | Receptores acoplados a proteina g humanos huerfanos. |
| US20030017528A1 (en) * | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| US7816492B2 (en) * | 1998-11-20 | 2010-10-19 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors |
| US6221660B1 (en) * | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| US20030125539A1 (en) * | 1999-02-22 | 2003-07-03 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| US6987005B1 (en) | 1999-05-28 | 2006-01-17 | H. Lundbeck A/S | DNA encoding SNORF33 receptor |
| GB9923177D0 (en) * | 1999-09-30 | 1999-12-01 | Pfizer Ltd | Novel polypeptide |
| CA2388308A1 (en) * | 1999-11-03 | 2001-05-10 | Klaus Ducker | Gpcr-kd5 polypeptides and dna sequences thereof |
| WO2001036473A2 (en) * | 1999-11-16 | 2001-05-25 | Pharmacia & Upjohn Company | Human g protein-coupled receptors |
| EP1287133B1 (en) * | 2000-05-18 | 2006-12-13 | Bayer HealthCare AG | Regulation of human dopamine-like g protein-coupled receptor |
| AU2002218509A1 (en) * | 2000-12-01 | 2002-06-11 | Yamanouchi Pharmaceutical Co..Ltd. | Method of screening remedy for diabetes |
| US20030064381A1 (en) * | 2001-03-07 | 2003-04-03 | Feder John N. | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY26, expressed highly in testis and gastrointestinal tissues |
| US20030045685A1 (en) * | 2001-03-09 | 2003-03-06 | Tularik Inc. | Novel receptors |
| US7053121B2 (en) * | 2001-03-19 | 2006-05-30 | Trustees Of The University Of Pennsylvania | Compositions and methods for regulating circadian rhythms |
| WO2003072014A2 (en) | 2002-02-25 | 2003-09-04 | Mpex Bioscience, Inc. | Minicell compositions and methods |
| WO2004024943A1 (ja) * | 2002-09-11 | 2004-03-25 | Yamanouchi Pharmaceutical Co., Ltd. | インスリン含量増加剤スクリーニング方法 |
| US20030143590A1 (en) * | 2002-11-18 | 2003-07-31 | Shyam Ramakrishnan | Regulation of human dopamine-like g protein- coupled receptor |
| US20080009551A1 (en) * | 2003-04-30 | 2008-01-10 | Arena Pharmaceuticals, Inc. | Methods and Compositions for Identifying Modulators of G Protein-Coupled Receptors |
| US7083933B1 (en) * | 2003-05-09 | 2006-08-01 | Prosidion Limited | Methods for identification of modulators of OSGPR116 activity |
| CA2525286C (en) * | 2003-05-20 | 2012-09-11 | The University Court Of The University Of Glasgow | Materials and methods relating to g-protein coupled receptor oligomers |
| US7309589B2 (en) * | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
| BRPI0516407A (pt) * | 2004-12-24 | 2008-09-02 | Prosidion Ltd | agonistas de receptor acoplado à proteìna g (gpr116) e uso destes para o tratamento de obesidade e diabetes |
| DOP2006000008A (es) * | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| US7306203B2 (en) * | 2005-01-28 | 2007-12-11 | Platt Robert E | Post assembly and spacer for use therewith |
| WO2006113236A2 (en) * | 2005-04-14 | 2006-10-26 | Cornell Research Foundation, Inc. | Novel chemical inhibitors of neutrophil activation through the sac-dependent pathway |
| KR20080027908A (ko) | 2005-06-30 | 2008-03-28 | 프로시디온 리미티드 | Gpcr 효능제 |
| US20090325924A1 (en) * | 2005-06-30 | 2009-12-31 | Stuart Edward | GPCR Agonists |
| AU2007238805B2 (en) * | 2006-04-11 | 2012-04-05 | Arena Pharmaceuticals, Inc. | Methods of using GPR119 receptor to identify compounds useful for increasing bone mass in an individual |
| PE20071221A1 (es) * | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
| US7638541B2 (en) | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
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| JP2010514832A (ja) * | 2007-01-04 | 2010-05-06 | プロシディオン・リミテッド | ピペリジンgpcrアゴニスト |
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| SI2114933T1 (sl) | 2007-01-04 | 2012-01-31 | Prosidion Ltd Windrush Court | Piperidinski gpcr-agonisti |
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| EP2200609A1 (en) * | 2007-09-10 | 2010-06-30 | Prosidion Limited | Compounds for the treatment of metabolic disorders |
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| GB0720390D0 (en) | 2007-10-18 | 2007-11-28 | Prosidion Ltd | G-Protein coupled receptor agonists |
| GB0720389D0 (en) | 2007-10-18 | 2008-11-12 | Prosidion Ltd | G-Protein Coupled Receptor Agonists |
| DK2280704T3 (en) * | 2008-03-31 | 2015-06-29 | Cymabay Therapeutics Inc | Oxymethylenarylforbindelser and uses thereof |
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| GB0812642D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
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| US5053337A (en) | 1989-10-30 | 1991-10-01 | Neurogenetic Corporation | DNA encoding an α2B -adrenergic receptor |
| US5661024A (en) | 1989-10-31 | 1997-08-26 | Synaptic Pharmaceutical Corporation | DNA encoding a human serotonic (5-HT2) receptor and uses thereof |
| US5155218A (en) | 1990-05-08 | 1992-10-13 | Neurogenetic Corporation | Dna encoding human 5-ht1d receptors |
| ES2085246T1 (es) | 1991-12-02 | 1996-06-01 | Synaptic Pharma Corp | Adn que codifica un receptor humano 5-ht1e y utilizaciones del mismo. |
| US5360735A (en) | 1992-01-08 | 1994-11-01 | Synaptic Pharmaceutical Corporation | DNA encoding a human 5-HT1F receptor, vectors, and host cells |
| WO1993025677A1 (en) | 1992-06-12 | 1993-12-23 | Garvan Institute Of Medical Research | DNA SEQUENCES ENCODING THE HUMAN A1, A2a and A2b ADENOSINE RECEPTORS |
| AU677968B2 (en) | 1992-09-25 | 1997-05-15 | H. Lundbeck A/S | DNA encoding human alpha 1 adrenergic receptors and uses thereof |
| US5472866A (en) | 1992-12-24 | 1995-12-05 | Synaptic Pharmaceutical Corporation | DNA encoding 5-HT4A serotonin receptors |
| US5516653A (en) | 1993-12-28 | 1996-05-14 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof |
| US5545549A (en) | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
| US5602024A (en) | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
| NZ510712A (en) | 1998-10-13 | 2004-11-26 | Arena Pharm Inc | Non-endogenous, constitutively activated human G protein-coupled receptors |
| ES2308759T3 (es) | 1998-11-20 | 2008-12-01 | Arena Pharmaceuticals, Inc. | Receptores acoplados a proteina g humanos huerfanos. |
| US20030017528A1 (en) * | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| EP1235860A2 (en) | 1999-12-10 | 2002-09-04 | Incyte Genomics, Inc. | G-protein coupled receptors |
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- 1999-08-13 US US09/387,699 patent/US6221660B1/en not_active Expired - Lifetime
-
2000
- 2000-02-22 PT PT00908748T patent/PT1075493E/pt unknown
- 2000-02-22 DK DK00908748T patent/DK1075493T3/da active
- 2000-02-22 ES ES00908748T patent/ES2312333T3/es not_active Expired - Lifetime
- 2000-02-22 CA CA002362906A patent/CA2362906A1/en not_active Abandoned
- 2000-02-22 DE DE60039948T patent/DE60039948D1/de not_active Expired - Lifetime
- 2000-02-22 AT AT00908748T patent/ATE405589T1/de active
- 2000-02-22 JP JP2000601126A patent/JP2002539772A/ja not_active Withdrawn
- 2000-02-22 WO PCT/US2000/004413 patent/WO2000050562A2/en not_active Ceased
- 2000-02-22 EP EP00908748A patent/EP1075493B1/en not_active Revoked
- 2000-02-22 AU AU30035/00A patent/AU777247B2/en not_active Withdrawn - After Issue
- 2000-08-17 US US09/641,259 patent/US6468756B1/en not_active Expired - Fee Related
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2002
- 2002-10-22 US US10/278,437 patent/US7416848B2/en not_active Expired - Fee Related
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2008
- 2008-11-12 CY CY20081101291T patent/CY1108503T1/el unknown
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2009
- 2009-09-14 JP JP2009212252A patent/JP2010063457A/ja not_active Withdrawn
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|---|---|
| US7416848B2 (en) | 2008-08-26 |
| JP2002539772A (ja) | 2002-11-26 |
| PT1075493E (pt) | 2008-12-03 |
| DE60039948D1 (de) | 2008-10-02 |
| WO2000050562A2 (en) | 2000-08-31 |
| US6468756B1 (en) | 2002-10-22 |
| CA2362906A1 (en) | 2000-08-31 |
| ES2312333T3 (es) | 2009-03-01 |
| DK1075493T3 (da) | 2009-01-12 |
| JP2010063457A (ja) | 2010-03-25 |
| EP1075493B1 (en) | 2008-08-20 |
| EP1075493A2 (en) | 2001-02-14 |
| US6221660B1 (en) | 2001-04-24 |
| EP1075493A4 (en) | 2004-10-27 |
| AU3003500A (en) | 2000-09-14 |
| AU777247B2 (en) | 2004-10-07 |
| US20030139590A1 (en) | 2003-07-24 |
| WO2000050562A3 (en) | 2000-12-14 |
| ATE405589T1 (de) | 2008-09-15 |
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