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CY1107810T1 - Συνθεσεις οι οποιες εχουν ενα συνδυασμο χαρακτηριστικων αμεσης απελευθερωσης και ελεγχομενης απελευθερωσης - Google Patents

Συνθεσεις οι οποιες εχουν ενα συνδυασμο χαρακτηριστικων αμεσης απελευθερωσης και ελεγχομενης απελευθερωσης

Info

Publication number
CY1107810T1
CY1107810T1 CY20071101497T CY071101497T CY1107810T1 CY 1107810 T1 CY1107810 T1 CY 1107810T1 CY 20071101497 T CY20071101497 T CY 20071101497T CY 071101497 T CY071101497 T CY 071101497T CY 1107810 T1 CY1107810 T1 CY 1107810T1
Authority
CY
Cyprus
Prior art keywords
compositions
combination
controlled
liberty
immediate
Prior art date
Application number
CY20071101497T
Other languages
English (en)
Inventor
Eugene R Cooper
Stephen B Ruddy
Original Assignee
Elan Pharma International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharma International Limited filed Critical Elan Pharma International Limited
Publication of CY1107810T1 publication Critical patent/CY1107810T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Αποκαλύπτονται συνθέσεις οι οποίες επιδεικνύουν ένα συνδυασμό χαρακτηριστικών άμεσης απελευθέρωσης και ελεγχόμενης απελευθέρωσης. Οι συνθέσεις περιλαμβάνουν τουλάχιστον ένα πτωχά διαλυτό δραστικό συστατικό το οποίο έχει ένα νανοσωματιδιακό μέγεθος σωματιδίων, τουλάχιστον ένα σταθεροποιητή επιφάνειας προσροφημένο επάνω στην επιφάνεια των σωματιδίων του νανοσωματιδιακού δραστικού παράγοντα, και τουλάχιστον ένα δραστικό συστατικό το οποίο έχει ένα μικροσωματιδιακό μέγεθος σωματιδίων.
CY20071101497T 2001-10-12 2007-11-22 Συνθεσεις οι οποιες εχουν ενα συνδυασμο χαρακτηριστικων αμεσης απελευθερωσης και ελεγχομενης απελευθερωσης CY1107810T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32840501P 2001-10-12 2001-10-12
EP02800993A EP1443912B1 (en) 2001-10-12 2002-10-11 Compositions having a combination of immediate release and controlled release characteristics

Publications (1)

Publication Number Publication Date
CY1107810T1 true CY1107810T1 (el) 2013-06-19

Family

ID=23280838

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101497T CY1107810T1 (el) 2001-10-12 2007-11-22 Συνθεσεις οι οποιες εχουν ενα συνδυασμο χαρακτηριστικων αμεσης απελευθερωσης και ελεγχομενης απελευθερωσης

Country Status (12)

Country Link
US (1) US6908626B2 (el)
EP (1) EP1443912B1 (el)
JP (5) JP2005508939A (el)
AT (1) ATE371442T1 (el)
AU (1) AU2002334939A1 (el)
CA (1) CA2463495C (el)
CY (1) CY1107810T1 (el)
DE (1) DE60222160T2 (el)
DK (1) DK1443912T3 (el)
ES (1) ES2292848T3 (el)
PT (1) PT1443912E (el)
WO (1) WO2003030872A2 (el)

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US6908626B2 (en) 2005-06-21
PT1443912E (pt) 2007-11-28
US20030137067A1 (en) 2003-07-24
WO2003030872A3 (en) 2003-07-31
ES2292848T3 (es) 2008-03-16
JP2005508939A (ja) 2005-04-07
CA2463495A1 (en) 2003-04-17
AU2002334939A1 (en) 2003-04-22
JP2013209422A (ja) 2013-10-10
EP1443912A2 (en) 2004-08-11
EP1443912B1 (en) 2007-08-29
ATE371442T1 (de) 2007-09-15
CA2463495C (en) 2011-05-24
DE60222160D1 (de) 2007-10-11
JP2017075182A (ja) 2017-04-20
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