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CY1106124T1 - Πιπepιδινυλοξυ και πυρρολιδινυλοξυφαινυλο οξαζολιδινονες σαν αντιβακτηριακα - Google Patents

Πιπepιδινυλοξυ και πυρρολιδινυλοξυφαινυλο οξαζολιδινονες σαν αντιβακτηριακα

Info

Publication number
CY1106124T1
CY1106124T1 CY20061101016T CY061101016T CY1106124T1 CY 1106124 T1 CY1106124 T1 CY 1106124T1 CY 20061101016 T CY20061101016 T CY 20061101016T CY 061101016 T CY061101016 T CY 061101016T CY 1106124 T1 CY1106124 T1 CY 1106124T1
Authority
CY
Cyprus
Prior art keywords
pyrrolidinyloxyphenyl
pipepidinyloxy
oxazolidinones
bacterial
compounds
Prior art date
Application number
CY20061101016T
Other languages
English (en)
Inventor
Michele Ann Weidner-Wells
Christine Boggs
Dennis Hlasta
Erin Nelson
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of CY1106124T1 publication Critical patent/CY1106124T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Πιπερίδινυλοξυ, πυρρολιδινυλοξυ και αζετιδινυλοξυ ενώσεις του τύπου (I): όπου το R1 είναι ένα ήμισυ πιπεριδινυλίου, πυρρολιδινυλίου ή αζετιδινυλίου όπως περιγράφεται στην παρούσα και στο οποίο τα υποκατάστατα έχουν την έννοια υποδεικνυόμενη στην περιγραφή. Αυτές οι ενώσεις είναι χρήσιμες σαν αντιβακτηριακοί παράγοντες.
CY20061101016T 1999-12-21 2006-07-21 Πιπepιδινυλοξυ και πυρρολιδινυλοξυφαινυλο οξαζολιδινονες σαν αντιβακτηριακα CY1106124T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17292399P 1999-12-21 1999-12-21
PCT/US2000/033835 WO2001046164A1 (en) 1999-12-21 2000-12-14 Piperidinyloxy and pyrrolidinyloxyphenyl oxazolidinones as antibacterials

Publications (1)

Publication Number Publication Date
CY1106124T1 true CY1106124T1 (el) 2011-06-08

Family

ID=22629768

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101016T CY1106124T1 (el) 1999-12-21 2006-07-21 Πιπepιδινυλοξυ και πυρρολιδινυλοξυφαινυλο οξαζολιδινονες σαν αντιβακτηριακα

Country Status (17)

Country Link
US (1) US6518285B2 (el)
EP (1) EP1246810B1 (el)
JP (1) JP2003518106A (el)
CN (1) CN1227238C (el)
AR (1) AR029420A1 (el)
AT (1) ATE326452T1 (el)
AU (1) AU784314B2 (el)
CA (1) CA2395204C (el)
CO (1) CO5280081A1 (el)
CY (1) CY1106124T1 (el)
DE (1) DE60028085T2 (el)
DK (1) DK1246810T3 (el)
ES (1) ES2265365T3 (el)
MX (1) MXPA02006323A (el)
MY (1) MY127677A (el)
PT (1) PT1246810E (el)
WO (1) WO2001046164A1 (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
WO2003031443A1 (en) * 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
US6940748B2 (en) 2002-05-16 2005-09-06 Micron Technology, Inc. Stacked 1T-nMTJ MRAM structure
AU2003202753A1 (en) * 2003-02-07 2004-08-30 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
EP1620098B1 (en) 2003-04-30 2008-06-11 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections
DE10340485B4 (de) * 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
CN106957316A (zh) 2003-12-18 2017-07-18 莫弗凯姆联合化学股份公司 噁唑烷酮‑喹诺酮杂化物抗生素
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
CN101084212A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶介导剂的用途
MX2007003319A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
MX2007003318A (es) 2004-09-20 2007-05-18 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
CA2580857A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
EP2029138A1 (en) 2005-06-03 2009-03-04 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
JP5114202B2 (ja) 2005-09-27 2013-01-09 塩野義製薬株式会社 Ｐｇｄ２受容体アンタゴニスト活性を有するスルホンアミド誘導体
JP5209254B2 (ja) * 2007-08-30 2013-06-12 日本曹達株式会社 置換フェノキシアザビシクロオクタン誘導体の製造方法
CN108785728A (zh) * 2017-05-05 2018-11-13 国家纳米科学中心 含药物中间体修饰的纳米金的抗菌敷料、其制备方法及应用
CN109503569B (zh) * 2019-01-03 2021-01-15 山东大学 噻唑类衍生物及其制备方法和应用
CN118076594A (zh) * 2021-10-12 2024-05-24 豪夫迈·罗氏有限公司 用于治疗细菌感染的磺酰基哌嗪基化合物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196771B (en) * 1983-06-07 1989-01-30 Du Pont Process for production of intermediers of derivatives of oxo-oxazolidinil-benzol having antibacterial effect
ES8506659A1 (es) 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US4705799A (en) 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
CA2119556C (en) 1991-11-01 2004-07-06 Michael Robert Barbachyn Substituted aryl- and heteroaryl-phenyloxazolidinones
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
JPH10508844A (ja) 1994-11-15 1998-09-02 ファルマシア・アンド・アップジョン・カンパニー 二環式オキサジンおよびチアジンオキサゾリジノン抗菌剤
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EP0807112B1 (en) 1995-02-03 2001-09-05 PHARMACIA & UPJOHN COMPANY Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
HRP960159A2 (en) 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
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JP2000204084A (ja) 1998-11-11 2000-07-25 Hokuriku Seiyaku Co Ltd チオカルバミド酸誘導体

Also Published As

Publication number Publication date
JP2003518106A (ja) 2003-06-03
ATE326452T1 (de) 2006-06-15
ES2265365T3 (es) 2007-02-16
US6518285B2 (en) 2003-02-11
EP1246810B1 (en) 2006-05-17
DE60028085T2 (de) 2006-12-07
CN1227238C (zh) 2005-11-16
CN1434810A (zh) 2003-08-06
CA2395204A1 (en) 2001-06-28
CA2395204C (en) 2008-02-05
AR029420A1 (es) 2003-06-25
WO2001046164A1 (en) 2001-06-28
DK1246810T3 (da) 2006-09-18
MY127677A (en) 2006-12-29
US20020103377A1 (en) 2002-08-01
MXPA02006323A (es) 2003-09-22
DE60028085D1 (de) 2006-06-22
AU784314B2 (en) 2006-03-09
PT1246810E (pt) 2006-08-31
EP1246810A1 (en) 2002-10-09
AU2261701A (en) 2001-07-03
CO5280081A1 (es) 2003-05-30

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