CY1105398T1 - 5΄ ESTs ΓΙΑ ΕΚΚΡΙΤΙΚΕΣ ΠΡΩΤΕΪΝΕΣ ΠΟΥ ΕΚΦΡΑΖΟΝΤΑΙ ΣΕ ΔΙΑΦΟΡΟΥΣ ΙΣΤΟΥΣ - Google Patents
5΄ ESTs ΓΙΑ ΕΚΚΡΙΤΙΚΕΣ ΠΡΩΤΕΪΝΕΣ ΠΟΥ ΕΚΦΡΑΖΟΝΤΑΙ ΣΕ ΔΙΑΦΟΡΟΥΣ ΙΣΤΟΥΣInfo
- Publication number
- CY1105398T1 CY1105398T1 CY20061100841T CY061100841T CY1105398T1 CY 1105398 T1 CY1105398 T1 CY 1105398T1 CY 20061100841 T CY20061100841 T CY 20061100841T CY 061100841 T CY061100841 T CY 061100841T CY 1105398 T1 CY1105398 T1 CY 1105398T1
- Authority
- CY
- Cyprus
- Prior art keywords
- ests
- secretory proteins
- different tissues
- proteins expressed
- sequences
- Prior art date
Links
- 102000040739 Secretory proteins Human genes 0.000 title abstract 2
- 108091058545 Secretory proteins Proteins 0.000 title abstract 2
- 108020004635 Complementary DNA Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 230000002759 chromosomal effect Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000013507 mapping Methods 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000013606 secretion vector Substances 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Οι αλληλουχίες των 5' ESTs που προέρχονται από mRNAs που κωδικοποιούν εκκριτικές πρωτεΐνες εσωκλείονται. Τα 5' ESTs μπορεί να χρησιμοποιηθούν για να αποκτηθούν cDNAs και γονιδιωματικά DNAs που αντιστοιχούν στα 5' ESTs. Τα 5' ESTs μπορούν επίσης να χρησιμοποιηθούν σε διαγνωστικές, δικαστικές, γονιδιακής θεραπείας και διαδικασίες χρωμοσωμικής χαρτογράφησης. Ανάντη ρυθμιστικές αλληλουχίες μπορούν επίσης να αποκτηθούν χρησιμοποιώντας τα 5' ESTs. Τα 5' ESTs μπορούν επίσης να χρησιμοποιηθούν για τον σχεδιασμό φορέων έκφρασης και φορέων έκκρισης.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90505197A | 1997-08-01 | 1997-08-01 | |
| PCT/IB1998/001237 WO1999006553A2 (en) | 1997-08-01 | 1998-07-31 | 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN VARIOUS TISSUES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1105398T1 true CY1105398T1 (el) | 2010-04-28 |
Family
ID=25420220
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061100841T CY1105398T1 (el) | 1997-08-01 | 2006-06-21 | 5΄ ESTs ΓΙΑ ΕΚΚΡΙΤΙΚΕΣ ΠΡΩΤΕΪΝΕΣ ΠΟΥ ΕΚΦΡΑΖΟΝΤΑΙ ΣΕ ΔΙΑΦΟΡΟΥΣ ΙΣΤΟΥΣ |
| CY20061101369T CY1105240T1 (el) | 1997-08-01 | 2006-09-21 | 5’ESTs ΓΙΑ ΕΚΚΡΙΤΙΚΕΣ ΠΡΩΤΕΪΝΕΣ ΠΟΥ ΕΚΦΡΑΖΟΝΤΑΙ ΣΕ ΔΙΑΦΟΡΟΥΣ ΙΣΤΟΥΣ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101369T CY1105240T1 (el) | 1997-08-01 | 2006-09-21 | 5’ESTs ΓΙΑ ΕΚΚΡΙΤΙΚΕΣ ΠΡΩΤΕΪΝΕΣ ΠΟΥ ΕΚΦΡΑΖΟΝΤΑΙ ΣΕ ΔΙΑΦΟΡΟΥΣ ΙΣΤΟΥΣ |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP1375514B1 (el) |
| JP (1) | JP2002525024A (el) |
| AT (2) | ATE338064T1 (el) |
| AU (1) | AU8555698A (el) |
| CA (1) | CA2296844A1 (el) |
| CY (2) | CY1105398T1 (el) |
| DE (2) | DE69835777T2 (el) |
| DK (2) | DK1000151T3 (el) |
| ES (2) | ES2260841T3 (el) |
| PT (2) | PT1000151E (el) |
| WO (1) | WO1999006553A2 (el) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000053752A2 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
| US6372473B1 (en) | 1997-05-28 | 2002-04-16 | Human Genome Sciences, Inc. | Tissue plasminogen activator-like protease |
| ES2359401T3 (es) * | 1997-08-01 | 2011-05-23 | Merck Serono Biodevelopment | ESTs 5¿PARA PROTEÍNAS SECRETADAS, EXPRESADAS EN DIVERSOS TEJIDOS. |
| IL121860A0 (en) | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
| US7220717B2 (en) | 1997-08-14 | 2007-05-22 | Yeda Research And Development Company Ltd. | Interleukin-18 binding proteins, their preparation and use |
| US7704944B2 (en) | 1997-08-14 | 2010-04-27 | Yeda Research And Development Company Ltd. | Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis |
| US6392019B1 (en) | 1997-11-22 | 2002-05-21 | John Ford | Antibodies specific for EGF motif proteins |
| US6808890B2 (en) | 1999-07-28 | 2004-10-26 | Nuvelo, Inc. | Method of detecting a cancerous cell expressing EGFL6, and EGF mutif protein |
| WO1999027096A1 (en) * | 1997-11-22 | 1999-06-03 | Hyseq, Inc. | A NOVEL EGF MOTIF PROTEIN OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN |
| JP2002505850A (ja) * | 1997-12-03 | 2002-02-26 | ジェネンテック・インコーポレーテッド | ポリペプチド及び同じものをコードしている核酸 |
| DE69824455T2 (de) * | 1997-12-11 | 2005-06-16 | Genentech Inc., San Francisco | PRO241 Polypeptide und dafür kodierende Nukleinsäuren |
| WO1999067387A2 (en) * | 1998-06-25 | 1999-12-29 | Millennium Pharmaceuticals, Inc. | Novel mp-7 protein and nucleic acid molecules and uses therefor |
| FR2796652B1 (fr) * | 1999-07-20 | 2003-03-21 | Inst Nat Sante Rech Med | Acides nucleiques codant pour des peptides possedant l'activite biologique de la sorbine |
| WO2001081584A2 (en) * | 2000-04-25 | 2001-11-01 | Millenium Pharmaceuticals, Inc. | 27960, a novel ubiquitin conjugating enzyme family member and uses therefor |
| US6740495B1 (en) | 2000-04-03 | 2004-05-25 | Rigel Pharmaceuticals, Inc. | Ubiquitin ligase assay |
| US6979551B2 (en) | 2000-04-03 | 2005-12-27 | Rigel Pharmaceuticals, Inc. | Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents |
| EP2280030A3 (en) | 2001-04-10 | 2011-06-15 | Agensys, Inc. | Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers |
| US7927597B2 (en) | 2001-04-10 | 2011-04-19 | Agensys, Inc. | Methods to inhibit cell growth |
| US7109302B1 (en) | 2002-04-01 | 2006-09-19 | Human Genome Sciences, Inc. | Antibodies that specifically bind to GMAD |
| JP6455983B2 (ja) * | 2013-10-25 | 2019-01-23 | 国立大学法人神戸大学 | アミロイド分解能を有する人工ペプチドおよびその利用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0832981A1 (en) * | 1987-02-17 | 1998-04-01 | Pharming B.V. | DNA sequences to target proteins to the mammary gland for efficient secretion |
| JP3337748B2 (ja) * | 1992-09-25 | 2002-10-21 | 財団法人神奈川科学技術アカデミー | 完全長cDNAの合成方法、その中間体の製造方法及び完全長cDNAを含む組換えベクターの製造方法 |
| FR2733762B1 (fr) * | 1995-05-02 | 1997-08-01 | Genset Sa | Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm et preparation d'arnm et d'adnc complet |
| US5707829A (en) * | 1995-08-11 | 1998-01-13 | Genetics Institute, Inc. | DNA sequences and secreted proteins encoded thereby |
| ES2359401T3 (es) * | 1997-08-01 | 2011-05-23 | Merck Serono Biodevelopment | ESTs 5¿PARA PROTEÍNAS SECRETADAS, EXPRESADAS EN DIVERSOS TEJIDOS. |
-
1998
- 1998-07-31 EP EP03016497A patent/EP1375514B1/en not_active Expired - Lifetime
- 1998-07-31 DK DK98936595T patent/DK1000151T3/da active
- 1998-07-31 AT AT03016497T patent/ATE338064T1/de active
- 1998-07-31 ES ES98936595T patent/ES2260841T3/es not_active Expired - Lifetime
- 1998-07-31 JP JP2000505294A patent/JP2002525024A/ja active Pending
- 1998-07-31 PT PT98936595T patent/PT1000151E/pt unknown
- 1998-07-31 WO PCT/IB1998/001237 patent/WO1999006553A2/en active IP Right Grant
- 1998-07-31 DE DE69835777T patent/DE69835777T2/de not_active Expired - Lifetime
- 1998-07-31 CA CA002296844A patent/CA2296844A1/en not_active Abandoned
- 1998-07-31 DK DK03016497T patent/DK1375514T3/da active
- 1998-07-31 ES ES03016497T patent/ES2266693T3/es not_active Expired - Lifetime
- 1998-07-31 PT PT03016497T patent/PT1375514E/pt unknown
- 1998-07-31 EP EP98936595A patent/EP1000151B1/en not_active Expired - Lifetime
- 1998-07-31 AT AT98936595T patent/ATE328078T1/de active
- 1998-07-31 AU AU85556/98A patent/AU8555698A/en not_active Abandoned
- 1998-07-31 DE DE69834727T patent/DE69834727T2/de not_active Expired - Lifetime
-
2006
- 2006-06-21 CY CY20061100841T patent/CY1105398T1/el unknown
- 2006-09-21 CY CY20061101369T patent/CY1105240T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1375514B1 (en) | 2006-08-30 |
| CY1105240T1 (el) | 2010-03-03 |
| ATE328078T1 (de) | 2006-06-15 |
| ATE338064T1 (de) | 2006-09-15 |
| ES2260841T3 (es) | 2006-11-01 |
| CA2296844A1 (en) | 1999-02-11 |
| EP1000151A2 (en) | 2000-05-17 |
| DK1000151T3 (da) | 2006-10-02 |
| DK1375514T3 (da) | 2007-01-08 |
| WO1999006553B1 (en) | 1999-05-27 |
| EP1000151B1 (en) | 2006-05-31 |
| JP2002525024A (ja) | 2002-08-13 |
| AU8555698A (en) | 1999-02-22 |
| WO1999006553A2 (en) | 1999-02-11 |
| PT1000151E (pt) | 2006-07-31 |
| EP1375514A2 (en) | 2004-01-02 |
| EP1375514A3 (en) | 2004-05-19 |
| DE69835777T2 (de) | 2007-09-06 |
| DE69834727T2 (de) | 2007-01-25 |
| WO1999006553A3 (en) | 1999-04-08 |
| DE69834727D1 (de) | 2006-07-06 |
| DE69835777D1 (de) | 2006-10-12 |
| ES2266693T3 (es) | 2007-03-01 |
| PT1375514E (pt) | 2006-10-31 |
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