CU20170011A7 - Composiciones que comprenden un polipéptido aglicosilado y métodos para la producción de las mismas - Google Patents
Composiciones que comprenden un polipéptido aglicosilado y métodos para la producción de las mismasInfo
- Publication number
- CU20170011A7 CU20170011A7 CUP2017000011A CU20170011A CU20170011A7 CU 20170011 A7 CU20170011 A7 CU 20170011A7 CU P2017000011 A CUP2017000011 A CU P2017000011A CU 20170011 A CU20170011 A CU 20170011A CU 20170011 A7 CU20170011 A7 CU 20170011A7
- Authority
- CU
- Cuba
- Prior art keywords
- compositions
- production
- methods
- polypeptide
- cellobiase
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000006995 beta-Glucosidase Human genes 0.000 abstract 3
- 108010047754 beta-Glucosidase Proteins 0.000 abstract 3
- 241000499912 Trichoderma reesei Species 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Processing Of Solid Wastes (AREA)
- Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
Abstract
<p>La presente invención se relaciona con composiciones que comprenden un polipéptido aglicosilado que tiene actividad de celobiasa y a métodos para la producción y uso de las mismas. La presente invención se basa, al menos en parte, en el descubrimiento sorprendente de que una celobiasa de Trichoderma reesei que fue expresada en una línea celular no fúngica y aislada a partir de una célula huésped que no glicosila significativamente la enzima, tuvo actividad específica más alta en sustrato puro que la celobiasa endógena (glicosilada y secretada) de T. reesei.</p>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462035346P | 2014-08-08 | 2014-08-08 | |
| PCT/US2015/044136 WO2016022878A1 (en) | 2014-08-08 | 2015-08-07 | Aglycosylated enzyme and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20170011A7 true CU20170011A7 (es) | 2017-08-08 |
Family
ID=55264604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2017000011A CU20170011A7 (es) | 2014-08-08 | 2015-08-07 | Composiciones que comprenden un polipéptido aglicosilado y métodos para la producción de las mismas |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10131894B2 (es) |
| EP (1) | EP3177719A4 (es) |
| JP (1) | JP2017524363A (es) |
| KR (1) | KR20170040246A (es) |
| CN (1) | CN106536730A (es) |
| AP (1) | AP2016009640A0 (es) |
| AU (1) | AU2015300897A1 (es) |
| BR (1) | BR112017002391A2 (es) |
| CA (1) | CA2955960A1 (es) |
| CU (1) | CU20170011A7 (es) |
| EA (1) | EA201790054A1 (es) |
| IL (1) | IL250272A0 (es) |
| MX (1) | MX2017001596A (es) |
| PH (1) | PH12016502604A1 (es) |
| SG (1) | SG11201610894UA (es) |
| WO (1) | WO2016022878A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201790054A1 (ru) * | 2014-08-08 | 2017-07-31 | Ксилеко, Инк. | Агликозилированные ферменты и их применение |
| US12397244B1 (en) | 2020-06-17 | 2025-08-26 | Plant Synergies, Llc | System and method for extracting noxious chemicals from naturally-occurring raw materials and creating useful products |
| CN115806950A (zh) * | 2022-11-24 | 2023-03-17 | 山东省科学院生物研究所 | 嗜热纤维二糖脱氢酶及其去糖基化酶和作为生物传感元件中的应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5028515B2 (es) | 1971-09-30 | 1975-09-16 | ||
| US6103464A (en) * | 1990-12-10 | 2000-08-15 | Genencor International, Inc. | Method of detecting DNA encoding a β-glucosidase from a filamentous fungus |
| CA2392060C (en) | 1999-11-19 | 2007-07-10 | Yissum Research Development Company Of The Hebrew University In Jerusalem | Aspergillus niger beta-glucosidase gene, protein and uses thereof |
| US6946277B2 (en) | 2001-01-31 | 2005-09-20 | Council Of Scientific And Industrial Research | Method for enhancing cellobiase activity of termitomyces clypeatus using a glycosylation inhibitor |
| FI120045B (fi) * | 2005-12-22 | 2009-06-15 | Roal Oy | Selluloosamateriaalin käsittely ja siinä käyttökelpoiset entsyymit |
| CN101517086A (zh) | 2006-07-21 | 2009-08-26 | 希乐克公司 | 生物质转化系统 |
| BRPI0714870A2 (pt) * | 2006-07-21 | 2013-05-28 | Novozymes Inc | mÉtodo para produzir um polipeptÍdeo secretado tendo atividade biolàgica, proteÍna de fusço isolada, polinucleotÍdeo isolado, construÇço de proteÍna de fusço, vetor de expressço, cÉlula hospedeira féngica, mÉtodos para degradar ou conventer um material celulàsico e para produzir uma substÂncia |
| EP2037274A1 (de) * | 2007-09-11 | 2009-03-18 | GALAB Technologies GmbH | Lektinbasierter Glykan-Assay |
| FR2935986B1 (fr) * | 2008-09-12 | 2012-11-23 | Inst Francais Du Petrole | Variants de beta-glucosidase a activite amelioree et leurs utilisations. |
| MX344902B (es) | 2009-05-20 | 2017-01-11 | Xyleco Inc | Procesar materiales conteniendo hidrocarburo. |
| IN2012DN03825A (es) * | 2009-11-20 | 2015-08-28 | Danisco Us Inc | |
| EA028976B1 (ru) | 2010-07-19 | 2018-01-31 | Ксилеко, Инк. | Переработка биомассы |
| AP4061A (en) | 2010-10-20 | 2017-03-09 | Xyleco Inc | Method of irradiating lignocellulosic materials with an electron beam |
| CA2829918A1 (en) | 2011-03-17 | 2012-09-20 | Danisco Us Inc. | Cellulase compositions and methods of using the same for improved conversion of lignocellulosic biomass into fermentable sugars |
| SG10201607328UA (en) | 2011-12-22 | 2016-10-28 | Xyleco Inc | Processing biomass |
| FR2994981B1 (fr) * | 2012-09-05 | 2014-09-12 | Centre Nat Rech Scient | Polypeptide a activite beta-glucosidase renforcee a basse temperature |
| US20150307871A1 (en) | 2012-12-07 | 2015-10-29 | Novozymes A/S | Method for generating site-specific mutations in filamentous fungi |
| EA201790054A1 (ru) | 2014-08-08 | 2017-07-31 | Ксилеко, Инк. | Агликозилированные ферменты и их применение |
-
2015
- 2015-08-07 EA EA201790054A patent/EA201790054A1/ru unknown
- 2015-08-07 CU CUP2017000011A patent/CU20170011A7/es unknown
- 2015-08-07 WO PCT/US2015/044136 patent/WO2016022878A1/en not_active Ceased
- 2015-08-07 MX MX2017001596A patent/MX2017001596A/es unknown
- 2015-08-07 EP EP15829718.4A patent/EP3177719A4/en not_active Withdrawn
- 2015-08-07 CN CN201580042200.6A patent/CN106536730A/zh active Pending
- 2015-08-07 KR KR1020177003329A patent/KR20170040246A/ko not_active Withdrawn
- 2015-08-07 CA CA2955960A patent/CA2955960A1/en not_active Abandoned
- 2015-08-07 BR BR112017002391A patent/BR112017002391A2/pt not_active IP Right Cessation
- 2015-08-07 AU AU2015300897A patent/AU2015300897A1/en not_active Abandoned
- 2015-08-07 AP AP2016009640A patent/AP2016009640A0/en unknown
- 2015-08-07 JP JP2017505517A patent/JP2017524363A/ja active Pending
- 2015-08-07 SG SG11201610894UA patent/SG11201610894UA/en unknown
- 2015-08-07 US US14/768,126 patent/US10131894B2/en active Active
-
2016
- 2016-12-23 PH PH12016502604A patent/PH12016502604A1/en unknown
-
2017
- 2017-01-24 IL IL250272A patent/IL250272A0/en unknown
-
2018
- 2018-10-04 US US16/151,690 patent/US20190024068A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20190024068A1 (en) | 2019-01-24 |
| AP2016009640A0 (en) | 2016-12-31 |
| US20170137797A1 (en) | 2017-05-18 |
| WO2016022878A1 (en) | 2016-02-11 |
| JP2017524363A (ja) | 2017-08-31 |
| IL250272A0 (en) | 2017-03-30 |
| EP3177719A4 (en) | 2018-04-04 |
| EP3177719A1 (en) | 2017-06-14 |
| BR112017002391A2 (pt) | 2017-11-28 |
| MX2017001596A (es) | 2017-05-15 |
| AU2015300897A1 (en) | 2017-01-05 |
| PH12016502604A1 (en) | 2017-04-24 |
| CA2955960A1 (en) | 2016-02-11 |
| CN106536730A (zh) | 2017-03-22 |
| SG11201610894UA (en) | 2017-01-27 |
| EA201790054A1 (ru) | 2017-07-31 |
| US10131894B2 (en) | 2018-11-20 |
| KR20170040246A (ko) | 2017-04-12 |
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