CU20120063A7 - A METHOD FOR OBTAINING REPROGRAMED DAILY CELLS - Google Patents
A METHOD FOR OBTAINING REPROGRAMED DAILY CELLSInfo
- Publication number
- CU20120063A7 CU20120063A7 CU2012000063A CU20120063A CU20120063A7 CU 20120063 A7 CU20120063 A7 CU 20120063A7 CU 2012000063 A CU2012000063 A CU 2012000063A CU 20120063 A CU20120063 A CU 20120063A CU 20120063 A7 CU20120063 A7 CU 20120063A7
- Authority
- CU
- Cuba
- Prior art keywords
- cells
- patient
- obtaining
- compromised
- transdifferentiated
- Prior art date
Links
- 230000001010 compromised effect Effects 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
Classifications
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
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- A61K35/14—Blood; Artificial blood
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
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- A61K35/39—Pancreas; Islets of Langerhans
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
Abstract
La presente invención se refiere a un método para la obtención de células dianas reprogramadas que pueden ser útiles para tratar diversas enfermedades, trastornos o afecciones en un paciente, mediante la utilización de células reprogramadas, como por ejemplo células retrodiferenciadas, transdiferenciadas o rediferenciadas. El método comprende obtener células comprometidas del paciente, retrodiferenciar las células comprometidas para obtener células diana retrodiferenciadas, y administrar las células retrodiferenciadas al paciente. En determinadas realizaciones, el método comprende obtener células comprometidas del paciente, transdiferenciar las células comprometidas para obtener células diana transdiferenciadas, y administrar las células diana transdiferenciadas al paciente. Las células diana retrodiferenciadas o transdiferenciadas reparan o reponen los tejidos o células en el paciente.The present invention relates to a method for obtaining reprogrammed target cells that can be useful for treating various diseases, disorders or conditions in a patient, by using reprogrammed cells, such as, for example, backdifferentiated, transdifferentiated or redifferentiated cells. The method comprises obtaining compromised cells from the patient, retrodifferentiating the compromised cells to obtain retrodifferentiated target cells, and administering the retrodifferentiated cells to the patient. In certain embodiments, the method comprises obtaining compromised cells from the patient, transdifferentiating the compromised cells to obtain transdifferentiated target cells, and administering the transdifferentiated target cells to the patient. Retrodifferentiated or transdifferentiated target cells repair or replenish tissues or cells in the patient.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2009/051396 WO2011048350A1 (en) | 2009-10-19 | 2009-10-19 | Treatment using reprogrammed mature adult cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20120063A7 true CU20120063A7 (en) | 2012-10-15 |
| CU24006B1 CU24006B1 (en) | 2014-06-27 |
Family
ID=42199514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2012000063A CU24006B1 (en) | 2009-10-19 | 2012-04-19 | A METHOD FOR OBTAINING REPROGRAMED DAILY CELLS |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP2490702A1 (en) |
| JP (1) | JP6073135B2 (en) |
| KR (1) | KR101766203B1 (en) |
| CN (1) | CN102647989A (en) |
| AU (1) | AU2009354350B2 (en) |
| CA (1) | CA2781522A1 (en) |
| CH (1) | CH704227B1 (en) |
| CU (1) | CU24006B1 (en) |
| IL (1) | IL218902A (en) |
| MA (1) | MA33740B1 (en) |
| MX (1) | MX2012004522A (en) |
| PH (1) | PH12012500714A1 (en) |
| RU (1) | RU2635317C2 (en) |
| TN (1) | TN2012000157A1 (en) |
| UA (1) | UA109265C2 (en) |
| WO (1) | WO2011048350A1 (en) |
| ZA (1) | ZA201202664B (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016044681A1 (en) | 2014-09-18 | 2016-03-24 | North Carolina State University | Mammalian lung spheroids and lung spheroid cells and uses thereof |
| JP6113133B2 (en) | 2014-11-06 | 2017-04-12 | 日本メナード化粧品株式会社 | Stem cell undifferentiated state maintenance agent and growth promoter |
| CN116712535A (en) | 2015-10-16 | 2023-09-08 | 纽约市哥伦比亚大学理事会 | Compositions and methods for inhibiting lineage specific antigens |
| CN107114355A (en) * | 2016-08-01 | 2017-09-01 | 北京世纪劲得生物技术有限公司 | A kind of fat cell protection liquid and preparation method thereof |
| AU2018229351B2 (en) | 2017-02-28 | 2024-01-04 | Vor Biopharma, Inc. | Compositions and methods for inhibition of lineage specific proteins |
| CN109731012A (en) * | 2017-10-30 | 2019-05-10 | 邹兆中 | It improves biological immune and treats the active method of active principle |
| CN109706119B (en) * | 2018-04-13 | 2020-11-27 | 诺未科技(北京)有限公司 | Culture system and method for expanding hematopoietic stem cells and application thereof |
| WO2020047164A1 (en) | 2018-08-28 | 2020-03-05 | Vor Biopharma, Inc | Genetically engineered hematopoietic stem cells and uses thereof |
| KR20200025210A (en) * | 2018-08-29 | 2020-03-10 | 주식회사 스템모어 | Composition for culturing dermal papilla cells and the method for culturing dermal papilla cells using the same |
| WO2021240204A1 (en) * | 2020-05-23 | 2021-12-02 | Pakravan Nafiseh | Sperm head for resolution of inflammation, tissue repair & regeneration, and restoration of tissue function: new approach of cell therapy |
| CN114231481B (en) * | 2021-12-21 | 2023-07-18 | 中国人民解放军总医院 | A chemical induction method for reprogramming dermal fibroblasts into endothelial progenitor cells |
| CN117025508A (en) * | 2022-05-10 | 2023-11-10 | 上海赛立维生物科技有限公司 | Kidney epithelial precursor-like cell, its preparation method, preparation and application |
| WO2024050517A1 (en) * | 2022-09-02 | 2024-03-07 | The University Of North Carolina At Chapel Hill | Methods of making and using anticancer reprogrammed b cells |
| WO2025143018A1 (en) * | 2023-12-28 | 2025-07-03 | サントリーホールディングス株式会社 | Composition for suppressing decline in curiosity or improving curiosity |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554512A (en) * | 1993-05-24 | 1996-09-10 | Immunex Corporation | Ligands for flt3 receptors |
| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| US9068164B1 (en) * | 1995-02-02 | 2015-06-30 | Tristem Trading (Cyprus) Limited | Method of preparing an undifferentiated cell |
| US7112440B2 (en) * | 1995-02-02 | 2006-09-26 | Ghazi Jaswinder Dhoot | Method of increasing the relative number of CD45 low cells in a cell population |
| EP0769203B1 (en) * | 1995-05-02 | 1999-08-18 | Koninklijke Philips Electronics N.V. | Colour cathode ray tube |
| US20050037490A1 (en) * | 1999-10-29 | 2005-02-17 | Lawrence Rosenberg | Medium for preparing dedifferentiated cells |
| TWI288779B (en) * | 2002-03-28 | 2007-10-21 | Blasticon Biotech Forschung | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
| US20080112937A1 (en) * | 2004-07-22 | 2008-05-15 | Lewis T Williams | Method of Producing Autologous Embryonic Stem Cells |
| WO2010115052A2 (en) * | 2009-04-03 | 2010-10-07 | The Mclean Hospital Corporation | Induced pluripotent stem cells |
-
2009
- 2009-10-19 WO PCT/GB2009/051396 patent/WO2011048350A1/en not_active Ceased
- 2009-10-19 RU RU2012120713A patent/RU2635317C2/en not_active IP Right Cessation
- 2009-10-19 CA CA2781522A patent/CA2781522A1/en not_active Abandoned
- 2009-10-19 PH PH1/2012/500714A patent/PH12012500714A1/en unknown
- 2009-10-19 CN CN2009801630439A patent/CN102647989A/en active Pending
- 2009-10-19 JP JP2012534757A patent/JP6073135B2/en not_active Expired - Fee Related
- 2009-10-19 AU AU2009354350A patent/AU2009354350B2/en not_active Ceased
- 2009-10-19 EP EP09736651A patent/EP2490702A1/en not_active Withdrawn
- 2009-10-19 UA UAA201205968A patent/UA109265C2/en unknown
- 2009-10-19 KR KR1020127012911A patent/KR101766203B1/en not_active Expired - Fee Related
- 2009-10-19 MX MX2012004522A patent/MX2012004522A/en unknown
- 2009-10-19 CH CH00524/12A patent/CH704227B1/en not_active IP Right Cessation
-
2012
- 2012-03-28 IL IL218902A patent/IL218902A/en not_active IP Right Cessation
- 2012-04-04 TN TNP2012000157A patent/TN2012000157A1/en unknown
- 2012-04-12 ZA ZA2012/02664A patent/ZA201202664B/en unknown
- 2012-04-19 CU CU2012000063A patent/CU24006B1/en active IP Right Grant
- 2012-05-11 MA MA34857A patent/MA33740B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2635317C2 (en) | 2017-11-10 |
| EP2490702A1 (en) | 2012-08-29 |
| IL218902A0 (en) | 2012-06-28 |
| IL218902A (en) | 2017-06-29 |
| AU2009354350A1 (en) | 2012-04-19 |
| WO2011048350A1 (en) | 2011-04-28 |
| TN2012000157A1 (en) | 2013-12-12 |
| RU2012120713A (en) | 2013-11-27 |
| ZA201202664B (en) | 2013-02-27 |
| CA2781522A1 (en) | 2011-04-28 |
| JP2013508343A (en) | 2013-03-07 |
| CH704227B1 (en) | 2015-05-15 |
| CN102647989A (en) | 2012-08-22 |
| MA33740B1 (en) | 2012-11-01 |
| KR101766203B1 (en) | 2017-08-08 |
| UA109265C2 (en) | 2015-08-10 |
| JP6073135B2 (en) | 2017-02-01 |
| CU24006B1 (en) | 2014-06-27 |
| PH12012500714A1 (en) | 2012-10-29 |
| AU2009354350B2 (en) | 2015-09-03 |
| MX2012004522A (en) | 2012-05-08 |
| KR20120099686A (en) | 2012-09-11 |
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