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CR8146A - Metodos para tratar canceres usando formas poliformicas de 3-(4-amino -1-oxo-1,3 dihidro-isoindol-2-il)- piperidina-2,6-dione - Google Patents

Metodos para tratar canceres usando formas poliformicas de 3-(4-amino -1-oxo-1,3 dihidro-isoindol-2-il)- piperidina-2,6-dione

Info

Publication number
CR8146A
CR8146A CR8146A CR8146A CR8146A CR 8146 A CR8146 A CR 8146A CR 8146 A CR8146 A CR 8146A CR 8146 A CR8146 A CR 8146A CR 8146 A CR8146 A CR 8146A
Authority
CR
Costa Rica
Prior art keywords
treat
methods
polypormal
canceres
piperidina
Prior art date
Application number
CR8146A
Other languages
English (en)
Inventor
B Zeldis Jerome
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33479228&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR8146(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US10/438,213 external-priority patent/US7968569B2/en
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of CR8146A publication Critical patent/CR8146A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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Abstract

Se presentan metodos para tratar, prevenir y/o manejar cancer asi como enfermedades y trastornos asociados con angiogenesis no deseada o caracterizados por ella. Los metodos especificos abarcan la administracion de un compuesto inmunomoduloatorio solo o en combinacion con un segundo ingrediente activo.
CR8146A 2003-05-15 2005-12-13 Metodos para tratar canceres usando formas poliformicas de 3-(4-amino -1-oxo-1,3 dihidro-isoindol-2-il)- piperidina-2,6-dione CR8146A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/438,213 US7968569B2 (en) 2002-05-17 2003-05-15 Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
US10/704,237 US7323479B2 (en) 2002-05-17 2003-11-06 Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline

Publications (1)

Publication Number Publication Date
CR8146A true CR8146A (es) 2006-03-24

Family

ID=33479228

Family Applications (2)

Application Number Title Priority Date Filing Date
CR8146A CR8146A (es) 2003-05-15 2005-12-13 Metodos para tratar canceres usando formas poliformicas de 3-(4-amino -1-oxo-1,3 dihidro-isoindol-2-il)- piperidina-2,6-dione
CR10582A CR10582A (es) 2003-05-15 2009-01-23 Metodos para tratar canceres usando formas poliformicas de 3-(-4-amino-1,3, dihidro-isoindol-2-il)-piperidina-2,6 dione (divisional exp. 8146)

Family Applications After (1)

Application Number Title Priority Date Filing Date
CR10582A CR10582A (es) 2003-05-15 2009-01-23 Metodos para tratar canceres usando formas poliformicas de 3-(-4-amino-1,3, dihidro-isoindol-2-il)-piperidina-2,6 dione (divisional exp. 8146)

Country Status (15)

Country Link
US (3) US7323479B2 (es)
EP (2) EP1635826A4 (es)
JP (1) JP2006528973A (es)
KR (1) KR20060012618A (es)
AU (2) AU2004240548B2 (es)
BR (1) BRPI0410306A (es)
CA (1) CA2525557A1 (es)
CR (2) CR8146A (es)
EC (1) ECSP056229A (es)
IL (1) IL171960A0 (es)
IS (1) IS8127A (es)
MX (1) MXPA05012155A (es)
NO (1) NO20055976L (es)
RU (1) RU2348407C2 (es)
WO (1) WO2004103274A2 (es)

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HU228769B1 (en) 1996-07-24 2013-05-28 Celgene Corp Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
ATE297911T1 (de) * 1998-03-16 2005-07-15 Celgene Corp 2-(2,6-dioxopiperidin-3-yl)isoindolin derivate, deren herstellung und deren verwendung als inhibitoren von entzündungszytokinen
US7629360B2 (en) * 1999-05-07 2009-12-08 Celgene Corporation Methods for the treatment of cachexia and graft v. host disease
CA2752140A1 (en) * 2002-05-17 2003-11-27 Celgene Corporation Methods and compositions using 3-(4-amino-1-oxo-1,3-dihydroisoindol-1-yl)-piperidine-2,6-dione for treatment and management of renal cancer
US7393862B2 (en) * 2002-05-17 2008-07-01 Celgene Corporation Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
US7968569B2 (en) 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
USRE48890E1 (en) 2002-05-17 2022-01-11 Celgene Corporation Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation
UA83504C2 (en) * 2003-09-04 2008-07-25 Селджин Корпорейшн Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
US20050100529A1 (en) * 2003-11-06 2005-05-12 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
US20050143344A1 (en) * 2003-12-30 2005-06-30 Zeldis Jerome B. Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases
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