CR11362A - BISPHOSPHONATES FOR RENT FROM 2 TO 5 CAROMON-IMIDAZOL ATOMS - Google Patents
BISPHOSPHONATES FOR RENT FROM 2 TO 5 CAROMON-IMIDAZOL ATOMSInfo
- Publication number
- CR11362A CR11362A CR11362A CR11362A CR11362A CR 11362 A CR11362 A CR 11362A CR 11362 A CR11362 A CR 11362A CR 11362 A CR11362 A CR 11362A CR 11362 A CR11362 A CR 11362A
- Authority
- CR
- Costa Rica
- Prior art keywords
- imidazol
- caromon
- bisphosphonates
- rent
- atoms
- Prior art date
Links
- 229940122361 Bisphosphonate Drugs 0.000 title 1
- 150000004663 bisphosphonates Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical group OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen acidos [(imidazol-1-il)-1-hidroxi-1-fosfono-etil] -fosfonicos sustituidos por alquilo de 2 a 5 atomos de carbono, asi como metodos o procesos para su fabricacion, su uso en la fabricacion de formulaciones farmaceuticas, su uso en el tratamiento de enfermedades, metodos para utilizarlos en el tratamiento de enfermedades, formulaciones farmaceuticas que los abarcan, y/o los compuestos para utilizarse en el tratamiento de enfermedades.[(Imidazol-1-yl) -1-hydroxy-1-phosphono-ethyl] -phosphonic acids substituted by alkyl of 2 to 5 carbon atoms, as well as methods or processes for their manufacture, their use in the manufacture of Pharmaceutical formulations, their use in the treatment of diseases, methods for use in the treatment of diseases, pharmaceutical formulations that cover them, and / or the compounds for use in the treatment of diseases.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07122016 | 2007-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR11362A true CR11362A (en) | 2010-06-14 |
Family
ID=39154111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR11362A CR11362A (en) | 2007-11-30 | 2010-04-09 | BISPHOSPHONATES FOR RENT FROM 2 TO 5 CAROMON-IMIDAZOL ATOMS |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7977323B2 (en) |
| EP (1) | EP2225252B1 (en) |
| JP (1) | JP5244917B2 (en) |
| KR (1) | KR20100092035A (en) |
| CN (1) | CN101835787A (en) |
| AR (1) | AR069437A1 (en) |
| AU (1) | AU2008328797B2 (en) |
| BR (1) | BRPI0819902A2 (en) |
| CA (1) | CA2701516A1 (en) |
| CL (1) | CL2008003545A1 (en) |
| CO (1) | CO6280421A2 (en) |
| CR (1) | CR11362A (en) |
| EA (1) | EA201000860A1 (en) |
| EC (1) | ECSP10010321A (en) |
| ES (1) | ES2386851T3 (en) |
| IL (1) | IL204657A0 (en) |
| MA (1) | MA31895B1 (en) |
| MX (1) | MX2010005786A (en) |
| NZ (1) | NZ584219A (en) |
| PE (1) | PE20091038A1 (en) |
| TN (1) | TN2010000138A1 (en) |
| TW (1) | TW200932248A (en) |
| WO (1) | WO2009068567A1 (en) |
| ZA (1) | ZA201001992B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009232033A1 (en) * | 2008-04-04 | 2009-10-08 | Novartis Ag | Pharmaceutical composition with bisphosphonate |
| US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| CA2769633C (en) | 2009-07-31 | 2017-06-06 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US8816082B2 (en) | 2010-05-28 | 2014-08-26 | The Royal Institution For The Advancement Of Learning/Mcgill University | Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof |
| US9290526B2 (en) | 2010-05-28 | 2016-03-22 | The Royal Institution For The Advancement Of Learning/Mcgill University | Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof |
| WO2012071517A2 (en) | 2010-11-24 | 2012-05-31 | Thar Pharmaceuticals, Inc. | Novel crystalline forms |
| CN102659840B (en) * | 2012-05-10 | 2013-08-14 | 苏州普瑞诺药物技术有限公司 | Imidazole diphosphonie acid compound and pharmaceutically-acceptable salt and medicinal application thereof |
| US10195218B2 (en) | 2016-05-31 | 2019-02-05 | Grunenthal Gmbh | Crystallization method and bioavailability |
| EP3698797A1 (en) | 2017-10-16 | 2020-08-26 | Tsinghua University | Mevalonic acid pathway inhibitor and pharmaceutical composition thereof |
| CN112980809B (en) * | 2021-03-17 | 2023-04-11 | 云南中烟工业有限责任公司 | Tobacco farnesyl pyrophosphate synthase gene and application thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE72816T1 (en) | 1986-11-21 | 1992-03-15 | Ciba Geigy Ag | NEW SUBSTITUTE ALKANEDIPHOSPHONE ACIDS. |
| HU215124B (en) * | 1991-02-26 | 1998-09-28 | Norwich Eaton Pharmaceuticals, Inc. | Process for producing synergetic pharmaceutical compositions containing estrogen and diphosphonate for treating osteoporosis |
| GB9324143D0 (en) | 1993-11-24 | 1994-01-12 | Schering Agrochemicals Ltd | Triazole phosphonate pesticides |
| GB0029018D0 (en) * | 2000-11-28 | 2001-01-10 | Strakan Group Plc | Dermatological formulations |
| GB0029111D0 (en) * | 2000-11-29 | 2001-01-10 | Novartis Ag | Organic compounds |
| WO2008128056A1 (en) | 2004-10-08 | 2008-10-23 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods with enhanced potency for multiple targets including fpps, ggpps, and dpps |
| WO2006039721A2 (en) | 2004-10-08 | 2006-04-13 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases |
| US20100047306A1 (en) | 2006-10-05 | 2010-02-25 | Novartis Ag | Pharmaceutical compositions comprising bisphosponates |
| JP2010522765A (en) | 2007-03-28 | 2010-07-08 | アレイ バイオファーマ、インコーポレイテッド | Imidazo [1,2-A] pyridine compounds as receptor tyrosine kinases |
-
2008
- 2008-11-26 AU AU2008328797A patent/AU2008328797B2/en not_active Ceased
- 2008-11-26 EP EP08854485A patent/EP2225252B1/en active Active
- 2008-11-26 CA CA2701516A patent/CA2701516A1/en not_active Abandoned
- 2008-11-26 JP JP2010535369A patent/JP5244917B2/en active Active
- 2008-11-26 WO PCT/EP2008/066245 patent/WO2009068567A1/en not_active Ceased
- 2008-11-26 KR KR1020107014395A patent/KR20100092035A/en not_active Ceased
- 2008-11-26 CN CN200880112351A patent/CN101835787A/en active Pending
- 2008-11-26 MX MX2010005786A patent/MX2010005786A/en active IP Right Grant
- 2008-11-26 BR BRPI0819902-7A patent/BRPI0819902A2/en not_active IP Right Cessation
- 2008-11-26 NZ NZ584219A patent/NZ584219A/en not_active IP Right Cessation
- 2008-11-26 US US12/323,696 patent/US7977323B2/en not_active Expired - Fee Related
- 2008-11-26 EA EA201000860A patent/EA201000860A1/en unknown
- 2008-11-26 ES ES08854485T patent/ES2386851T3/en active Active
- 2008-11-27 AR ARP080105163A patent/AR069437A1/en active IP Right Grant
- 2008-11-27 PE PE2008001990A patent/PE20091038A1/en not_active Application Discontinuation
- 2008-11-28 TW TW097146484A patent/TW200932248A/en unknown
- 2008-11-28 CL CL2008003545A patent/CL2008003545A1/en unknown
-
2010
- 2010-03-19 ZA ZA2010/01992A patent/ZA201001992B/en unknown
- 2010-03-22 IL IL204657A patent/IL204657A0/en unknown
- 2010-03-26 TN TNP2010000138A patent/TN2010000138A1/en unknown
- 2010-04-09 CR CR11362A patent/CR11362A/en unknown
- 2010-05-26 CO CO10063351A patent/CO6280421A2/en not_active Application Discontinuation
- 2010-05-31 MA MA32880A patent/MA31895B1/en unknown
- 2010-06-30 EC EC2010010321A patent/ECSP10010321A/en unknown
-
2011
- 2011-05-26 US US13/116,671 patent/US20110224173A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2225252B1 (en) | 2012-06-27 |
| ECSP10010321A (en) | 2010-08-31 |
| AU2008328797A1 (en) | 2009-06-04 |
| JP2011504908A (en) | 2011-02-17 |
| US7977323B2 (en) | 2011-07-12 |
| PE20091038A1 (en) | 2009-08-19 |
| KR20100092035A (en) | 2010-08-19 |
| ZA201001992B (en) | 2010-12-29 |
| US20090143337A1 (en) | 2009-06-04 |
| WO2009068567A1 (en) | 2009-06-04 |
| MX2010005786A (en) | 2010-06-09 |
| BRPI0819902A2 (en) | 2015-05-19 |
| CA2701516A1 (en) | 2009-06-04 |
| CN101835787A (en) | 2010-09-15 |
| TW200932248A (en) | 2009-08-01 |
| MA31895B1 (en) | 2010-12-01 |
| AU2008328797B2 (en) | 2011-11-03 |
| JP5244917B2 (en) | 2013-07-24 |
| ES2386851T3 (en) | 2012-09-03 |
| NZ584219A (en) | 2012-03-30 |
| CL2008003545A1 (en) | 2009-06-05 |
| US20110224173A1 (en) | 2011-09-15 |
| EA201000860A1 (en) | 2010-12-30 |
| EP2225252A1 (en) | 2010-09-08 |
| TN2010000138A1 (en) | 2011-09-26 |
| AR069437A1 (en) | 2010-01-20 |
| CO6280421A2 (en) | 2011-05-20 |
| IL204657A0 (en) | 2010-11-30 |
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