CO6160319A2 - Moduladores del metabolismo y tratamiento de los trastornos metabolicos - Google Patents
Moduladores del metabolismo y tratamiento de los trastornos metabolicosInfo
- Publication number
- CO6160319A2 CO6160319A2 CO08136750A CO08136750A CO6160319A2 CO 6160319 A2 CO6160319 A2 CO 6160319A2 CO 08136750 A CO08136750 A CO 08136750A CO 08136750 A CO08136750 A CO 08136750A CO 6160319 A2 CO6160319 A2 CO 6160319A2
- Authority
- CO
- Colombia
- Prior art keywords
- medicament
- production
- human
- individual
- treatment
- Prior art date
Links
- 208000030159 metabolic disease Diseases 0.000 title abstract 2
- 230000004060 metabolic process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- 239000003814 drug Substances 0.000 abstract 5
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 2
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 235000012631 food intake Nutrition 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 208000006575 hypertriglyceridemia Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000036186 satiety Effects 0.000 abstract 1
- 235000019627 satiety Nutrition 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000004584 weight gain Effects 0.000 abstract 1
- 235000019786 weight gain Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1.- Un compuesto seleccionado entre los compuestos de fórmula (I): y sus sales, solvatos e hidratos farmacéuticamente aceptables. 2.- Una composición farmacéutica que comprende un compuesto de la reivindicación 1 y un portador farmacéuticamente aceptable.3.- El uso de un compuesto de acuerdo con la reivindicación 1 para la producción de un medicamento para usar en el tratamiento de un trastorno metabólico. 4.- El uso de un compuesto de acuerdo con la reivindicación 1, para la producción de un medicamento para usar en el tratamiento de la diabetes tipo I, la diabetes tipo II, la tolerancia inadecuada a la glucosa, la resistencia a la insulina, la hiperglucemia, la hiperlipidemia, la hipertrigliceridemia, la hipercolesterolemia, la dislipidemia o el síndrome X. 5.- El uso de un compuesto de acuerdo con la reivindicación 1 para la producción de un medicamento para usar en la disminución del consumo de alimentos en un individuo. 6.- El uso de un compuesto de acuerdo con la reivindicación 1 para la producción de un medicamento para usar en la inducción de saciedad en un individuo. 7.- El uso de un compuesto de acuerdo con la reivindicación 1 para la producción de un medicamento para usar en el control o la disminución del aumento de peso en un individuo. 8.- El uso de acuerdo con cualquiera de las reivindicaciones 5 a 7, donde dicho individuo es un mamífero. 9.- El uso de acuerdo con la reivindicación 8, donde dicho mamífero es un ser humano. 10.- El uso de acuerdo con la reivindicación 9, donde dicho ser humano tiene un índice de masa corporal entre aproximadamente 18,5 y aproximadamente 45. 11.- El uso de acuerdo con la reivindicación 9, donde dicho ser humano tiene un índice de masa corporal entre aproximadamente 25 y aproximadamente 45. 12.- El uso de acuerdo con la reivindicación 9, donde dicho ser humano tiene un índice de masa corporal entre aproximadamente 30 y aproximadamente 45.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81927806P | 2006-07-06 | 2006-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6160319A2 true CO6160319A2 (es) | 2010-05-20 |
Family
ID=38895258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO08136750A CO6160319A2 (es) | 2006-07-06 | 2008-12-24 | Moduladores del metabolismo y tratamiento de los trastornos metabolicos |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US20090286816A1 (es) |
| EP (1) | EP2051976B1 (es) |
| JP (1) | JP2009542699A (es) |
| KR (1) | KR20090029781A (es) |
| CN (1) | CN101484441A (es) |
| AR (1) | AR061968A1 (es) |
| AT (1) | ATE469145T1 (es) |
| AU (1) | AU2007269571A1 (es) |
| BR (1) | BRPI0713998A2 (es) |
| CA (1) | CA2656623A1 (es) |
| CL (1) | CL2007001971A1 (es) |
| CO (1) | CO6160319A2 (es) |
| CR (1) | CR10537A (es) |
| DE (1) | DE602007006815D1 (es) |
| DK (1) | DK2051976T3 (es) |
| EA (1) | EA200970088A1 (es) |
| EC (1) | ECSP099037A (es) |
| ES (1) | ES2344965T3 (es) |
| GT (1) | GT200800306A (es) |
| IL (1) | IL195851A0 (es) |
| MA (1) | MA30602B1 (es) |
| MX (1) | MX2008016253A (es) |
| NO (1) | NO20090591L (es) |
| PE (1) | PE20080519A1 (es) |
| SV (1) | SV2009003146A (es) |
| TN (1) | TNSN08533A1 (es) |
| TW (1) | TW200811147A (es) |
| UY (1) | UY30467A1 (es) |
| WO (1) | WO2008005569A2 (es) |
| ZA (1) | ZA200900055B (es) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| DE602004009295T2 (de) | 2003-01-14 | 2008-07-03 | Arena Pharmaceuticals, Inc., San Diego | 1,2,3-trisubstituierte aryl- und heteroarylderivate als modulatoren des metabolismus zur vorbeugung und behandlung von metabolismus-bedingten krankheiten wie diabetes oder hyperglykämie |
| US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| MX2008014024A (es) | 2006-05-04 | 2008-11-14 | Boehringer Ingelheim Int | Formas poliformas. |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EP2197873B1 (en) | 2007-09-20 | 2014-07-16 | Irm Llc | Compounds and compositions as modulators of gpr119 activity |
| PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| EP2108960A1 (en) | 2008-04-07 | 2009-10-14 | Arena Pharmaceuticals, Inc. | Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| MX2011002558A (es) * | 2008-09-10 | 2011-04-26 | Boehringer Ingelheim Int | Terapia de combinacion para el tratamiento de diabetes y estados relacionados. |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| EP2382216A1 (en) | 2008-12-23 | 2011-11-02 | Boehringer Ingelheim International GmbH | Salt forms of organic compound |
| TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
| EP2399914A4 (en) | 2009-02-18 | 2012-08-29 | Takeda Pharmaceutical | FUSED HETEROCYCLIC CORE COMPOUND |
| US20100298362A1 (en) * | 2009-05-20 | 2010-11-25 | Xun Li | Process for the preparation of 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester |
| EA201200046A1 (ru) | 2009-06-24 | 2012-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Новые соединения, фармацевтическая композиция и связанные с ними способы |
| JP2012530758A (ja) | 2009-06-24 | 2012-12-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規化合物、医薬組成物及びそれに関する方法 |
| EP3646859A1 (en) | 2009-11-27 | 2020-05-06 | Boehringer Ingelheim International GmbH | Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin |
| SG10201500639TA (en) | 2010-01-27 | 2015-03-30 | Arena Pharm Inc | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US20130109703A1 (en) | 2010-03-18 | 2013-05-02 | Boehringer Ingelheim International Gmbh | Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions |
| AU2011249722B2 (en) | 2010-05-05 | 2015-09-17 | Boehringer Ingelheim International Gmbh | Combination therapy |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| CN106975074A (zh) | 2010-06-24 | 2017-07-25 | 勃林格殷格翰国际有限公司 | 糖尿病治疗 |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2012025811A1 (en) | 2010-08-23 | 2012-03-01 | Lupin Limited | Indolylpyrimidines as modulators of gpr119 |
| PH12013500547A1 (en) | 2010-09-22 | 2013-06-10 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| US9000175B2 (en) | 2010-11-26 | 2015-04-07 | Lupin Limited | Bicyclic GPR119 modulators |
| EA031618B1 (ru) | 2011-06-09 | 2019-01-31 | Ризен Фармасьютикалз Са | Соединения-модуляторы gpr-119 |
| PH12014500137A1 (en) | 2011-07-15 | 2017-08-18 | Boehringer Ingelheim Int | Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| WO2013171167A1 (en) | 2012-05-14 | 2013-11-21 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
| US20130303554A1 (en) | 2012-05-14 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Use of a dpp-4 inhibitor in sirs and/or sepsis |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| JP6522502B2 (ja) | 2013-07-29 | 2019-05-29 | 協和発酵キリン株式会社 | Wntシグナル阻害剤 |
| EP3110449B1 (en) | 2014-02-28 | 2023-06-28 | Boehringer Ingelheim International GmbH | Medical use of a dpp-4 inhibitor |
| CN104003942A (zh) * | 2014-03-10 | 2014-08-27 | 常熟市南湖实业化工有限公司 | 避免串温现象产生的5-甲氧基-4,6-二氯嘧啶制备方法 |
| ES2995737T3 (en) | 2015-01-06 | 2025-02-11 | Arena Pharm Inc | Compound for use in treating conditions related to the s1p1 receptor |
| CN105111151B (zh) * | 2015-04-17 | 2018-09-28 | 成都理工大学 | 作为PPAR-γ调节剂的氨基嘧啶衍生物 |
| MA42807A (fr) | 2015-06-22 | 2018-07-25 | Arena Pharm Inc | Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1 |
| WO2017211979A1 (en) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinations of linagliptin and metformin |
| WO2018151873A1 (en) | 2017-02-16 | 2018-08-23 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of primary biliary cholangitis |
| EP3801459B1 (en) | 2018-06-06 | 2024-08-07 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the s1p1 receptor |
| CN108658871B (zh) * | 2018-06-19 | 2020-10-30 | 舞阳威森生物医药有限公司 | 周效磺胺中间体4,6-二氯-5-甲氧基嘧啶的制备方法 |
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-
2007
- 2007-07-02 TW TW096124029A patent/TW200811147A/zh unknown
- 2007-07-04 PE PE2007000859A patent/PE20080519A1/es not_active Application Discontinuation
- 2007-07-05 DK DK07810278.7T patent/DK2051976T3/da active
- 2007-07-05 CN CNA2007800250772A patent/CN101484441A/zh not_active Withdrawn
- 2007-07-05 AT AT07810278T patent/ATE469145T1/de not_active IP Right Cessation
- 2007-07-05 EP EP07810278A patent/EP2051976B1/en active Active
- 2007-07-05 EA EA200970088A patent/EA200970088A1/ru unknown
- 2007-07-05 ES ES07810278T patent/ES2344965T3/es active Active
- 2007-07-05 CL CL2007001971A patent/CL2007001971A1/es unknown
- 2007-07-05 WO PCT/US2007/015670 patent/WO2008005569A2/en not_active Ceased
- 2007-07-05 KR KR1020097000107A patent/KR20090029781A/ko not_active Withdrawn
- 2007-07-05 CA CA002656623A patent/CA2656623A1/en not_active Abandoned
- 2007-07-05 DE DE602007006815T patent/DE602007006815D1/de active Active
- 2007-07-05 BR BRPI0713998-5A patent/BRPI0713998A2/pt not_active IP Right Cessation
- 2007-07-05 US US12/307,549 patent/US20090286816A1/en not_active Abandoned
- 2007-07-05 AU AU2007269571A patent/AU2007269571A1/en not_active Withdrawn
- 2007-07-05 JP JP2009518398A patent/JP2009542699A/ja not_active Withdrawn
- 2007-07-05 MX MX2008016253A patent/MX2008016253A/es active IP Right Grant
- 2007-07-06 AR ARP070103027A patent/AR061968A1/es unknown
- 2007-07-06 UY UY30467A patent/UY30467A1/es unknown
-
2008
- 2008-01-05 ZA ZA200900055A patent/ZA200900055B/xx unknown
- 2008-12-10 IL IL195851A patent/IL195851A0/en unknown
- 2008-12-19 CR CR10537A patent/CR10537A/es not_active Application Discontinuation
- 2008-12-24 CO CO08136750A patent/CO6160319A2/es unknown
- 2008-12-25 TN TNP2008000533A patent/TNSN08533A1/en unknown
- 2008-12-29 GT GT200800306A patent/GT200800306A/es unknown
-
2009
- 2009-01-06 SV SV2009003146A patent/SV2009003146A/es unknown
- 2009-01-06 EC EC2009009037A patent/ECSP099037A/es unknown
- 2009-01-27 MA MA31591A patent/MA30602B1/fr unknown
- 2009-02-06 NO NO20090591A patent/NO20090591L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN08533A1 (en) | 2010-04-14 |
| BRPI0713998A2 (pt) | 2012-11-20 |
| NO20090591L (no) | 2009-02-06 |
| PE20080519A1 (es) | 2008-05-16 |
| JP2009542699A (ja) | 2009-12-03 |
| GT200800306A (es) | 2009-04-20 |
| DK2051976T3 (da) | 2010-09-20 |
| UY30467A1 (es) | 2008-02-29 |
| AR061968A1 (es) | 2008-08-10 |
| HK1128921A1 (en) | 2009-11-13 |
| ZA200900055B (en) | 2009-12-30 |
| WO2008005569A2 (en) | 2008-01-10 |
| CR10537A (es) | 2009-01-27 |
| CL2007001971A1 (es) | 2008-01-25 |
| AU2007269571A1 (en) | 2008-01-10 |
| CN101484441A (zh) | 2009-07-15 |
| TW200811147A (en) | 2008-03-01 |
| US20090286816A1 (en) | 2009-11-19 |
| ATE469145T1 (de) | 2010-06-15 |
| CA2656623A1 (en) | 2008-01-10 |
| ECSP099037A (es) | 2009-02-27 |
| IL195851A0 (en) | 2009-09-01 |
| SV2009003146A (es) | 2009-11-04 |
| MX2008016253A (es) | 2009-02-25 |
| DE602007006815D1 (de) | 2010-07-08 |
| EP2051976B1 (en) | 2010-05-26 |
| EP2051976A2 (en) | 2009-04-29 |
| ES2344965T3 (es) | 2010-09-10 |
| WO2008005569A3 (en) | 2008-04-10 |
| KR20090029781A (ko) | 2009-03-23 |
| EA200970088A1 (ru) | 2009-06-30 |
| MA30602B1 (fr) | 2009-07-01 |
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