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CO5670370A2 - Proceso para la preparacion de derivados de tetrazol a partir de azidas de organo-boro y de organo-aluminio - Google Patents

Proceso para la preparacion de derivados de tetrazol a partir de azidas de organo-boro y de organo-aluminio

Info

Publication number
CO5670370A2
CO5670370A2 CO06014919A CO06014919A CO5670370A2 CO 5670370 A2 CO5670370 A2 CO 5670370A2 CO 06014919 A CO06014919 A CO 06014919A CO 06014919 A CO06014919 A CO 06014919A CO 5670370 A2 CO5670370 A2 CO 5670370A2
Authority
CO
Colombia
Prior art keywords
residue
organo
formula
azidas
aluminio
Prior art date
Application number
CO06014919A
Other languages
English (en)
Inventor
Gottfried Sedelmeier
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO5670370A2 publication Critical patent/CO5670370A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06—Aluminium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06—Aluminium compounds
    • C07F5/061—Aluminium compounds with C-aluminium linkage
    • C07F5/066—Aluminium compounds with C-aluminium linkage compounds with Al linked to an element other than Al, C, H or halogen (this includes Al-cyanide linkage)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1.- Un proceso para la fabricación de un tetrazol de la Fórmula:o un tautómero o una sal del mismo, en donde R representa un residuo orgánico;el cual comprende: (i) hacer reaccionar un compuesto de la fórmula R-CN (lIa) con una azida de la fórmula (R1)(R2)M-N3 (lIb), en donde R tiene el significado definido anteriormente; R1 y R2, independientemente uno del otro, representan un residuo orgánico, tal como un residuo alifático, un residuo alicíclico, un residuo heteroalicíclico; un residuo alicíclico-alifático; un residuo heteroalicíclico-alifático; un residuo aromático carbocíclico o heterocíclico;un residuo aralifático, o un residuo heteroaralifático, estando cada residuo, independientemente uno del otro, insustituido o sustituido; y M es boro o aluminio; y (ii) aislar el compuesto resultante de la Fórmula (I).
CO06014919A 2003-07-15 2006-02-15 Proceso para la preparacion de derivados de tetrazol a partir de azidas de organo-boro y de organo-aluminio CO5670370A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0316546.1A GB0316546D0 (en) 2003-07-15 2003-07-15 Process for the manufacture of organic compounds

Publications (1)

Publication Number Publication Date
CO5670370A2 true CO5670370A2 (es) 2006-08-31

Family

ID=27763861

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06014919A CO5670370A2 (es) 2003-07-15 2006-02-15 Proceso para la preparacion de derivados de tetrazol a partir de azidas de organo-boro y de organo-aluminio

Country Status (34)

Country Link
US (3) US7943647B2 (es)
EP (2) EP2116548A1 (es)
JP (2) JP5052132B2 (es)
KR (5) KR20130140915A (es)
CN (1) CN100475823C (es)
AR (1) AR045995A1 (es)
AT (1) ATE450541T1 (es)
AU (1) AU2004263265C1 (es)
BR (1) BRPI0412558A (es)
CA (1) CA2532175A1 (es)
CO (1) CO5670370A2 (es)
CY (1) CY1109809T1 (es)
DE (1) DE602004024402D1 (es)
DK (1) DK1646636T3 (es)
EC (2) ECSP066282A (es)
ES (1) ES2336333T3 (es)
GB (1) GB0316546D0 (es)
HR (1) HRP20100088T1 (es)
IL (2) IL172946A (es)
IS (1) IS8303A (es)
MA (1) MA27906A1 (es)
MX (1) MXPA06000561A (es)
MY (1) MY176840A (es)
NO (1) NO20060729L (es)
NZ (1) NZ544644A (es)
PE (2) PE20091786A1 (es)
PL (1) PL1646636T3 (es)
PT (1) PT1646636E (es)
RU (2) RU2006104322A (es)
SI (1) SI1646636T1 (es)
TN (1) TNSN06008A1 (es)
TW (2) TWI372754B (es)
WO (1) WO2005014602A1 (es)
ZA (1) ZA200600312B (es)

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EP1661891A1 (en) * 2004-11-30 2006-05-31 KRKA, D.D., Novo Mesto A process for the synthesis of valsartan
GB0514206D0 (en) * 2005-07-11 2005-08-17 Novartis Ag Organic compounds
GB0514686D0 (en) * 2005-07-18 2005-08-24 Novartis Ag Organic compounds
KR101250820B1 (ko) * 2005-08-16 2013-04-04 수벤 라이프 사이언시스 리미티드 개선된 로사르탄 제조 방법
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KR101942064B1 (ko) * 2011-04-25 2019-01-24 주식회사 엘지화학 신규한 아연 아지드 착물 및 이를 이용한 테트라졸 유도체의 제조방법
CN102351804B (zh) * 2011-09-30 2013-07-31 浙江新赛科药业有限公司 一种缬沙坦消旋体的回收方法
CN102702117B (zh) * 2012-06-01 2016-04-13 浙江沙星医药化工有限公司 一种制备5-(4’-溴代甲基-2-联苯基)-1-三苯甲基四氮唑的方法
CN103265560B (zh) * 2013-05-17 2016-05-04 中国科学院上海高等研究院 棉酚/棉酮衍生物及其制备方法和抗肿瘤药物中的应用
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KR102090155B1 (ko) * 2019-11-22 2020-03-17 국방과학연구소 베타인 수용액 내에서 5-치환-1h-테트라졸의 제조방법
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CN116375687A (zh) * 2021-12-22 2023-07-04 浙江华海药业股份有限公司 一种高纯度的氯沙坦钾及其制备方法

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Publication number Publication date
IL172946A (en) 2012-01-31
JP2011184451A (ja) 2011-09-22
TWI340742B (en) 2011-04-21
BRPI0412558A (pt) 2006-09-19
PE20091786A1 (es) 2009-12-14
KR20110082096A (ko) 2011-07-15
AU2004263265B2 (en) 2007-09-06
JP2009513555A (ja) 2009-04-02
HRP20100088T1 (hr) 2010-06-30
NO20060729L (no) 2006-04-04
PL1646636T3 (pl) 2010-05-31
TWI372754B (en) 2012-09-21
MXPA06000561A (es) 2006-03-30
PT1646636E (pt) 2010-01-29
TNSN06008A1 (en) 2007-10-03
IS8303A (is) 2006-02-14
CY1109809T1 (el) 2014-09-10
PE20050710A1 (es) 2005-09-28
EP1646636A1 (en) 2006-04-19
DE602004024402D1 (de) 2010-01-14
JP5052132B2 (ja) 2012-10-17
AU2004263265C1 (en) 2008-09-25
KR20120018826A (ko) 2012-03-05
ECSP066282A (es) 2006-07-28
IL216449A0 (en) 2011-12-29
TW200510347A (en) 2005-03-16
EP1646636B1 (en) 2009-12-02
ES2336333T3 (es) 2010-04-12
KR20130127011A (ko) 2013-11-21
DK1646636T3 (da) 2010-04-06
MY176840A (en) 2020-08-24
IL172946A0 (en) 2006-06-11
US20070043098A1 (en) 2007-02-22
US7943647B2 (en) 2011-05-17
ATE450541T1 (de) 2009-12-15
WO2005014602A1 (en) 2005-02-17
EP2116548A1 (en) 2009-11-11
MA27906A1 (fr) 2006-05-02
RU2006104322A (ru) 2007-09-20
CN100475823C (zh) 2009-04-08
KR20060038994A (ko) 2006-05-04
KR101336435B1 (ko) 2013-12-04
CN1852908A (zh) 2006-10-25
AU2004263265A1 (en) 2005-02-17
ZA200600312B (en) 2007-02-28
GB0316546D0 (en) 2003-08-20
KR20130140915A (ko) 2013-12-24
SI1646636T1 (sl) 2010-03-31
ECSP11006282A (es) 2011-08-31
CA2532175A1 (en) 2005-02-17
TW201038540A (en) 2010-11-01
US20120330026A1 (en) 2012-12-27
US8569528B2 (en) 2013-10-29
US20110184187A1 (en) 2011-07-28
HK1093509A1 (en) 2007-03-02
RU2012149012A (ru) 2014-05-27
AR045995A1 (es) 2005-11-23
NZ544644A (en) 2008-07-31

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