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CO5160296A1 - NEW FORMS OF PRESENTATION FOR ACTIVE LABOR AGENTS IN THE MIDDLE ACID, ACTIVE AGENT UNIT AND PROCESS FOR THE PRODUCTION OF SUCH AGENT UNIT - Google Patents

NEW FORMS OF PRESENTATION FOR ACTIVE LABOR AGENTS IN THE MIDDLE ACID, ACTIVE AGENT UNIT AND PROCESS FOR THE PRODUCTION OF SUCH AGENT UNIT

Info

Publication number
CO5160296A1
CO5160296A1 CO00040091A CO00040091A CO5160296A1 CO 5160296 A1 CO5160296 A1 CO 5160296A1 CO 00040091 A CO00040091 A CO 00040091A CO 00040091 A CO00040091 A CO 00040091A CO 5160296 A1 CO5160296 A1 CO 5160296A1
Authority
CO
Colombia
Prior art keywords
agent unit
active
active agent
production
agents
Prior art date
Application number
CO00040091A
Other languages
Spanish (es)
Inventor
Dietrich Rango
Rudolf Linder
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7910295&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO5160296(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of CO5160296A1 publication Critical patent/CO5160296A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una forma de presentación para agentes activos lábiles en medio ácido, que contiene adyuvantes farmacéuticos y unidades individuales múltiples de agente activo, caracterizada porque el agente activo lábil en medio ácido se encuentra en las unidades individuales de agente activo en una matriz constituida por una mezcla que contiene al menos un alcohol graso y al menos una parafina sólida.Igualmente, se refiere a una unidad de agente activo que contiene un agente activo lábil en medio ácido y a un proceso para la producción de dicha una unidad de agente activo.The present invention relates to a presentation form for labile active agents in acidic medium, which contains pharmaceutical adjuvants and multiple individual units of active agent, characterized in that the labile active agent in acidic medium is found in the individual active agent units in a matrix consisting of a mixture containing at least one fatty alcohol and at least one solid paraffin. Likewise, it refers to an active agent unit containing a labile active agent in acidic medium and a process for the production of said an agent unit active.

CO00040091A 1999-06-07 2000-05-30 NEW FORMS OF PRESENTATION FOR ACTIVE LABOR AGENTS IN THE MIDDLE ACID, ACTIVE AGENT UNIT AND PROCESS FOR THE PRODUCTION OF SUCH AGENT UNIT CO5160296A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19925710A DE19925710C2 (en) 1999-06-07 1999-06-07 New preparation and dosage form containing an acid labile proton pump inhibitor

Publications (1)

Publication Number Publication Date
CO5160296A1 true CO5160296A1 (en) 2002-05-30

Family

ID=7910295

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00040091A CO5160296A1 (en) 1999-06-07 2000-05-30 NEW FORMS OF PRESENTATION FOR ACTIVE LABOR AGENTS IN THE MIDDLE ACID, ACTIVE AGENT UNIT AND PROCESS FOR THE PRODUCTION OF SUCH AGENT UNIT

Country Status (6)

Country Link
AR (1) AR024310A1 (en)
CO (1) CO5160296A1 (en)
DE (1) DE19925710C2 (en)
MY (1) MY138975A (en)
PE (1) PE20010303A1 (en)
TW (1) TWI255720B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4241041B2 (en) 2000-12-07 2009-03-18 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Paste-form pharmaceutical product containing an acid-degradable active ingredient
DE10061135C1 (en) * 2000-12-07 2002-11-07 Byk Gulden Lomberg Chem Fab Stable gel preparation for oral administration of acid-labile drug, especially proton pump inhibitor, comprises multiple drug units dispersed in gel base
UA80393C2 (en) * 2000-12-07 2007-09-25 Алтана Фарма Аг Pharmaceutical preparation comprising an pde inhibitor dispersed on a matrix
BR0115989A (en) * 2000-12-07 2004-01-13 Altana Pharma Ag A pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient.
ES2380654T3 (en) * 2000-12-07 2012-05-17 Nycomed Gmbh Rapid disintegration tablet comprising a labile active ingredient in acid medium
DE10061136C1 (en) * 2000-12-07 2002-10-24 Byk Gulden Lomberg Chem Fab Stable, rapidly disintegrating tablets containing proton pump inhibitors, useful for treating elevated gastric secretion, comprising multiple drug units and auxiliaries including basic filler
DE10061138C1 (en) * 2000-12-07 2002-08-14 Byk Gulden Lomberg Chem Fab Pharmaceutical preparation in the form of a juice containing an acid-labile active ingredient
DE10061137B4 (en) * 2000-12-07 2016-10-06 Takeda Gmbh New pharmaceutical preparation
SE0101379D0 (en) 2001-04-18 2001-04-18 Diabact Ab Composition that inhibits gastric acid secretion
EP1429745A2 (en) 2001-09-28 2004-06-23 McNEIL-PPC, INC. Composite dosage forms having an inlaid portion
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EP1572151A1 (en) * 2002-07-03 2005-09-14 Abbott Laboratories Liquid dosage forms of proton pump inhibitors
DE10244129B4 (en) * 2002-09-23 2006-04-20 Iongate Biosciences Gmbh H + -K + -ATPase assay
SE0203065D0 (en) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
DE602004023921D1 (en) 2003-03-10 2009-12-17 Nycomed Gmbh NEW PROCESS FOR THE PRODUCTION OF ROLUMUMILAST
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
US8663694B2 (en) 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2725924C3 (en) * 1977-06-08 1980-11-06 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Process for the production of spherical particles from low-melting organic substances
DE3524572A1 (en) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K SOLID PHARMACEUTICAL FORMS FOR PERORAL USE CONTAINING 9-DEOXO-11-DEOXY-9,11- (IMINO (2- (2-METHOXYETHOXY) ETHYLIDEN) -OXY) - (9S) -ERYTHROMYCIN AND METHOD FOR THE PRODUCTION THEREOF
JP2681373B2 (en) * 1988-07-18 1997-11-26 塩野義製薬株式会社 Method for manufacturing sustained-release preparation

Also Published As

Publication number Publication date
PE20010303A1 (en) 2001-03-09
DE19925710C2 (en) 2002-10-10
DE19925710A1 (en) 2000-12-14
TWI255720B (en) 2006-06-01
MY138975A (en) 2009-08-28
AR024310A1 (en) 2002-09-25

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