CO2022007507A2 - Use of reboxetine to treat disorders of the nervous system - Google Patents
Use of reboxetine to treat disorders of the nervous systemInfo
- Publication number
- CO2022007507A2 CO2022007507A2 CONC2022/0007507A CO2022007507A CO2022007507A2 CO 2022007507 A2 CO2022007507 A2 CO 2022007507A2 CO 2022007507 A CO2022007507 A CO 2022007507A CO 2022007507 A2 CO2022007507 A2 CO 2022007507A2
- Authority
- CO
- Colombia
- Prior art keywords
- reboxetine
- nervous system
- treat disorders
- esreboxetine
- cataplexy
- Prior art date
Links
- CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 title abstract 4
- 229960003770 reboxetine Drugs 0.000 title abstract 4
- 210000000653 nervous system Anatomy 0.000 title 1
- CBQGYUDMJHNJBX-OALUTQOASA-N (2S)-2-[(S)-(2-ethoxyphenoxy)-phenylmethyl]morpholine Chemical compound CCOC1=CC=CC=C1O[C@@H](C=1C=CC=CC=1)[C@H]1OCCNC1 CBQGYUDMJHNJBX-OALUTQOASA-N 0.000 abstract 3
- 229950008247 esreboxetine Drugs 0.000 abstract 3
- 201000003631 narcolepsy Diseases 0.000 abstract 3
- 208000023046 narcolepsy-cataplexy syndrome Diseases 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
En el presente documento se describen los métodos para el tratamiento de la narcolepsia con cataplexia, los cuales comprenden la administración de la reboxetina (la que incluye la esreboxetina) a un ser humano que lo necesite. La reboxetina (la que incluye la esreboxetina) también se puede utilizar en la elaboración de un medicamento para el tratamiento de la narcolepsia con cataplexia. También se dan a conocer en este documento los kits que comprenden una composición farmacéutica que comprende la reboxetina (la que incluye la esreboxetina) y las instrucciones para usar la composición farmacéutica para el tratamiento de la narcolepsia con cataplexia en un ser humano.Described herein are methods for the treatment of narcolepsy with cataplexy, which comprise the administration of reboxetine (which includes esreboxetine) to a human in need thereof. Reboxetine (which includes esreboxetine) can also be used in the manufacture of a drug for the treatment of narcolepsy with cataplexy. Also disclosed herein are kits comprising a pharmaceutical composition comprising reboxetine (which includes esreboxetine) and instructions for using the pharmaceutical composition for the treatment of narcolepsy with cataplexy in a human.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962943077P | 2019-12-03 | 2019-12-03 | |
| US201962946295P | 2019-12-10 | 2019-12-10 | |
| US16/740,329 US20200147093A1 (en) | 2018-10-15 | 2020-01-10 | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| US16/740,409 US11351175B2 (en) | 2018-10-15 | 2020-01-11 | Use of reboxetine to treat narcolepsy |
| US16/740,411 US20200147096A1 (en) | 2018-10-15 | 2020-01-11 | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| US16/740,410 US20200147095A1 (en) | 2018-10-15 | 2020-01-11 | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| PCT/US2020/062560 WO2021113163A1 (en) | 2019-12-03 | 2020-11-30 | Use of reboxetine to treat nervous system disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2022007507A2 true CO2022007507A2 (en) | 2022-06-21 |
Family
ID=81851750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2022/0007507A CO2022007507A2 (en) | 2019-12-03 | 2022-05-31 | Use of reboxetine to treat disorders of the nervous system |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP4069244A4 (en) |
| JP (1) | JP2023504685A (en) |
| KR (1) | KR20220108122A (en) |
| CN (1) | CN114746097A (en) |
| AU (2) | AU2020395082A1 (en) |
| BR (1) | BR112022010677A2 (en) |
| CA (1) | CA3163505A1 (en) |
| CO (1) | CO2022007507A2 (en) |
| CR (1) | CR20220247A (en) |
| IL (1) | IL293536A (en) |
| MX (1) | MX2022006630A (en) |
| PE (1) | PE20230181A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL197983B1 (en) * | 1999-07-01 | 2008-05-30 | Upjohn Co | Application of optically pure (S,S)-reboxetine and the pharmaceutically acceptable salts thereof for drug preparation |
| ATE319453T1 (en) * | 1999-07-01 | 2006-03-15 | Pharmacia & Upjohn Co Llc | REBOXETINE FOR THE TREATMENT OF FIBROMYALGIA AND OTHER SOMATOFORM DISORDERS |
| EP2167066B1 (en) * | 2007-05-07 | 2013-06-26 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of attention deficit disorders |
| KR102192554B1 (en) * | 2013-03-13 | 2020-12-18 | 에스케이바이오팜 주식회사 | Treatment of cataplexy |
-
2020
- 2020-11-30 PE PE2022000980A patent/PE20230181A1/en unknown
- 2020-11-30 BR BR112022010677A patent/BR112022010677A2/en unknown
- 2020-11-30 CN CN202080083484.4A patent/CN114746097A/en active Pending
- 2020-11-30 AU AU2020395082A patent/AU2020395082A1/en not_active Abandoned
- 2020-11-30 EP EP20895126.9A patent/EP4069244A4/en active Pending
- 2020-11-30 JP JP2022533248A patent/JP2023504685A/en active Pending
- 2020-11-30 KR KR1020227022167A patent/KR20220108122A/en not_active Ceased
- 2020-11-30 MX MX2022006630A patent/MX2022006630A/en unknown
- 2020-11-30 CA CA3163505A patent/CA3163505A1/en active Pending
- 2020-11-30 IL IL293536A patent/IL293536A/en unknown
- 2020-11-30 CR CR20220247A patent/CR20220247A/en unknown
-
2022
- 2022-05-31 CO CONC2022/0007507A patent/CO2022007507A2/en unknown
-
2024
- 2024-05-31 AU AU2024203676A patent/AU2024203676A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN114746097A (en) | 2022-07-12 |
| MX2022006630A (en) | 2022-06-24 |
| EP4069244A4 (en) | 2023-12-20 |
| EP4069244A1 (en) | 2022-10-12 |
| PE20230181A1 (en) | 2023-02-01 |
| CA3163505A1 (en) | 2021-06-10 |
| KR20220108122A (en) | 2022-08-02 |
| CR20220247A (en) | 2022-08-18 |
| BR112022010677A2 (en) | 2022-08-16 |
| AU2020395082A1 (en) | 2022-06-09 |
| AU2024203676A1 (en) | 2024-06-20 |
| JP2023504685A (en) | 2023-02-06 |
| IL293536A (en) | 2022-08-01 |
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