CO2017005624A2 - Composiciones oftálmicas estabilizadas de omega 3 - Google Patents
Composiciones oftálmicas estabilizadas de omega 3Info
- Publication number
- CO2017005624A2 CO2017005624A2 CONC2017/0005624A CO2017005624A CO2017005624A2 CO 2017005624 A2 CO2017005624 A2 CO 2017005624A2 CO 2017005624 A CO2017005624 A CO 2017005624A CO 2017005624 A2 CO2017005624 A2 CO 2017005624A2
- Authority
- CO
- Colombia
- Prior art keywords
- ophthalmic compositions
- stabilized
- stabilized omega
- omega
- keratoconjunctivitis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se proporcionan composiciones oftálmicas estabilizadas que contienen aceites omega 3, que son útiles como lágrimas artificiales y como composiciones oftálmicas para diagnosticar, tratar o prevenir la queratoconjuntivitis o síndrome del ojo seco en un ser humano u otro mamífero.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462083980P | 2014-11-25 | 2014-11-25 | |
| PCT/US2015/062213 WO2016085885A1 (en) | 2014-11-25 | 2015-11-23 | Stabilized omega-3 ophthalmic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2017005624A2 true CO2017005624A2 (es) | 2017-10-20 |
Family
ID=54784036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2017/0005624A CO2017005624A2 (es) | 2014-11-25 | 2017-06-06 | Composiciones oftálmicas estabilizadas de omega 3 |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US10279005B2 (es) |
| EP (1) | EP3223794A1 (es) |
| JP (1) | JP6768653B2 (es) |
| KR (1) | KR102487299B1 (es) |
| CN (1) | CN107106483B (es) |
| AU (1) | AU2015353701B2 (es) |
| CA (1) | CA2967413C (es) |
| CL (1) | CL2017001301A1 (es) |
| CO (1) | CO2017005624A2 (es) |
| IL (1) | IL252161B (es) |
| MX (2) | MX372988B (es) |
| NZ (1) | NZ732058A (es) |
| PH (1) | PH12017500922A1 (es) |
| RU (1) | RU2697844C9 (es) |
| SG (1) | SG11201704167PA (es) |
| UA (1) | UA121399C2 (es) |
| WO (1) | WO2016085885A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019524892A (ja) | 2016-08-19 | 2019-09-05 | アクリビスタ エルエルシーAkrivista,Llc | ドライアイ症候群を診断及び治療する方法ならびにヒト眼を治療するための組成物 |
| WO2019036625A1 (en) | 2017-08-18 | 2019-02-21 | Akrivista, LLC | METHODS FOR DIAGNOSING AND TREATING DRY-LIKE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE |
| IL272601B2 (en) * | 2017-08-27 | 2025-03-01 | Rhodes Tech Inc | Pharmaceutical compositions for the treatment of ophthalmic conditions |
| CN109364153A (zh) * | 2018-11-30 | 2019-02-22 | 河南科高中标检测技术有限公司 | 一种缓解和治疗电子辐射类视疲劳的组合物、制备方法及其应用 |
| CN114096339B (zh) | 2019-05-02 | 2024-04-12 | 特清公司 | 从滴眼剂中去除防腐剂 |
| AU2020405238A1 (en) * | 2019-12-19 | 2022-07-14 | TearClear Corp. | Preservative removal from eye drops |
| KR102365008B1 (ko) * | 2020-06-23 | 2022-02-23 | 주식회사태준제약 | 디쿠아포솔을 포함하는 점안 조성물 |
| CN115996705A (zh) * | 2020-06-23 | 2023-04-21 | 株式会社泰俊制药 | 包含地夸磷索的眼用组合物 |
| MX2023001557A (es) | 2020-08-05 | 2023-03-08 | Tearclear Corp | Sistemas y metodos para la eliminacion de conservantes de formulaciones oftalmaticas. |
| US11951123B2 (en) | 2022-01-12 | 2024-04-09 | Platform Ophthalmic Innovations, LLC | Fortified nutritional lubricating drops for dry eye disease |
| US12397017B2 (en) | 2022-01-12 | 2025-08-26 | Platform Ophthalmic Innovations, LLC | Fortified nutritional lubricating drops for dry eye disease |
| IT202300000006A1 (it) | 2023-01-02 | 2024-07-02 | Offhealth Spa | “formulazione liposomiale di curcumina per uso oftalmico e suo metodo di preparazione industriale atto a stabilizzare nel tempo la concentrazione della stessa curcumina” |
| WO2025072929A1 (en) * | 2023-09-28 | 2025-04-03 | The Regents Of The University Of California | Methods and compositions of treating age-related conditions |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4201706A (en) | 1978-09-22 | 1980-05-06 | Burton, Parsons & Company, Inc. | Treatment of corneal edema |
| EP0028110B1 (en) | 1979-10-26 | 1984-03-07 | Smith and Nephew Associated Companies p.l.c. | Autoclavable emulsions |
| JPS56104814A (en) | 1980-01-25 | 1981-08-20 | Kunihiro Okanoe | Preparation of eye drop |
| US4649047A (en) | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
| ATE109970T1 (de) | 1987-09-03 | 1994-09-15 | Univ Georgia Res Found | Cyclosporin-augenmittel. |
| US4839342A (en) | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
| FR2638089A1 (fr) | 1988-10-26 | 1990-04-27 | Sandoz Sa | Nouvelles compositions ophtalmiques a base d'une cyclosporine |
| IT1224795B (it) | 1988-12-01 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento |
| CA2037057C (en) | 1989-08-03 | 1995-03-21 | Takakazu Morita | Photostabilizing method for ophthalmic solutions and the resulting opthalmic solutions therefrom |
| US5681555A (en) | 1991-04-22 | 1997-10-28 | Gleich; Gerald J. | Method for the treatment of bronchial asthma by parenteral administration of anionic polymers |
| DE4229494A1 (de) | 1992-09-04 | 1994-03-10 | Basotherm Gmbh | Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks |
| US5474979A (en) | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| CA2199610A1 (en) | 1994-09-14 | 1996-03-21 | Taisho Pharmaceutical Co., Ltd. | Eye drops for repairing repairing corneal damage |
| US5980865A (en) | 1995-08-18 | 1999-11-09 | Baker Norton Pharmaceuticals, Inc. | Method for treating late phase allergic reactions and inflammatory diseases |
| FI106923B (fi) | 1997-01-03 | 2001-05-15 | Cultor Ltd Finnsugar Bioproduc | Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa |
| AR002194A1 (es) | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| US5981607A (en) | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
| IT1302307B1 (it) | 1998-09-01 | 2000-09-05 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil |
| AU1295200A (en) | 1998-11-13 | 2000-06-05 | Continental Projects Limited | Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions |
| US6228392B1 (en) | 1999-04-29 | 2001-05-08 | Gene Tools, Llc | Osmotic delivery composition, solution, and method |
| EP1301210A2 (en) | 2000-07-14 | 2003-04-16 | Allergan, Inc. | Compositions containing therapeutically active components having enhanced solubility |
| AU781975B2 (en) | 2000-09-14 | 2005-06-23 | Hayashibara Co., Ltd | Pharmaceutical composition for ophthalmic use |
| ATE443749T1 (de) | 2000-11-08 | 2009-10-15 | Fxs Ventures Llc | Verbesserte ophthalmische und kontaktlinsenlösungen mit einfachen sacchariden als konservierungsverbesserer |
| US7045121B2 (en) | 2001-12-14 | 2006-05-16 | Allergan, Inc. | Ophthalmic compositions for lubricating eyes and methods for making and using same |
| WO2004028536A1 (en) | 2002-09-30 | 2004-04-08 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
| US20040137079A1 (en) | 2003-01-08 | 2004-07-15 | Cook James N. | Contact lens and eye drop rewetter compositions and methods |
| US6635654B1 (en) | 2003-01-09 | 2003-10-21 | Allergan, Inc. | Ophthalmic compositions containing loratadine |
| US20060251685A1 (en) | 2003-03-18 | 2006-11-09 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye |
| JPWO2004084877A1 (ja) | 2003-03-26 | 2006-06-29 | 株式会社メニコン | 眼科用組成物 |
| ZA200510025B (en) * | 2003-06-11 | 2007-03-28 | Novacea Inc | Pharmaceutical compositions comprising active vitamin D compounds |
| US20050009836A1 (en) | 2003-06-26 | 2005-01-13 | Laskar Paul A. | Ophthalmic composition containing quinolones and method of use |
| US20070265341A1 (en) | 2004-07-01 | 2007-11-15 | The Schepens Eye Research Institute Inc. | Compositions and methods for treating eye disorders and conditions |
| KR20070040381A (ko) | 2004-07-01 | 2007-04-16 | 셰펜스 아이 리써치 | 눈의 장애 및 상태를 치료하는 조성물 및 방법 |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| US7297679B2 (en) | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
| US9561178B2 (en) | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
| WO2008035246A2 (en) | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions containing quaternary ammonium compounds |
| WO2008027341A2 (en) | 2006-08-30 | 2008-03-06 | Merck & Co., Inc. | Topical ophthalmic formulations |
| CN101668511A (zh) | 2007-02-28 | 2010-03-10 | 阿西克斯医疗公司 | 正常化睑板腺分泌的方法和化合物 |
| JP4929245B2 (ja) | 2008-07-31 | 2012-05-09 | 株式会社ベッセル工業 | 工具類のグリップ |
| WO2010047927A1 (en) | 2008-10-20 | 2010-04-29 | Allergan, Inc. | Ophthalmic compositions useful for improving visual acuity |
| IT1393419B1 (it) * | 2009-03-19 | 2012-04-20 | Medivis S R L | Composizioni oftalmiche a base di acidi grassi polinsaturi omega-3 e omega-6. |
| US9480645B2 (en) * | 2009-06-02 | 2016-11-01 | Abbott Medical Optics Inc. | Omega-3 oil containing ophthalmic emulsions |
| EP2437762B1 (en) * | 2009-06-05 | 2017-08-09 | Allergan, Inc. | Artificial tears and therapeutic uses |
| US8957048B2 (en) | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| RU2014129268A (ru) * | 2011-12-16 | 2016-02-10 | Аллерган, Инк. | Офтальмологические составы, которые содержат привитые сополимеры поливинилкапролактам-поливинилацетат-полиэтиленгликоля |
| CN102934703B (zh) * | 2012-11-13 | 2015-07-15 | 中国食品发酵工业研究院 | 一种亚麻籽油微胶囊及其生产方法 |
-
2015
- 2015-11-23 JP JP2017527899A patent/JP6768653B2/ja active Active
- 2015-11-23 MX MX2017006474A patent/MX372988B/es active IP Right Grant
- 2015-11-23 EP EP15805372.8A patent/EP3223794A1/en active Pending
- 2015-11-23 US US14/949,352 patent/US10279005B2/en active Active
- 2015-11-23 RU RU2017117558A patent/RU2697844C9/ru active
- 2015-11-23 KR KR1020177017234A patent/KR102487299B1/ko active Active
- 2015-11-23 CA CA2967413A patent/CA2967413C/en active Active
- 2015-11-23 SG SG11201704167PA patent/SG11201704167PA/en unknown
- 2015-11-23 CN CN201580062648.4A patent/CN107106483B/zh active Active
- 2015-11-23 UA UAA201704859A patent/UA121399C2/uk unknown
- 2015-11-23 NZ NZ732058A patent/NZ732058A/en not_active IP Right Cessation
- 2015-11-23 WO PCT/US2015/062213 patent/WO2016085885A1/en not_active Ceased
- 2015-11-23 AU AU2015353701A patent/AU2015353701B2/en active Active
-
2017
- 2017-05-08 IL IL252161A patent/IL252161B/en active IP Right Grant
- 2017-05-17 MX MX2020004076A patent/MX2020004076A/es unknown
- 2017-05-18 PH PH12017500922A patent/PH12017500922A1/en unknown
- 2017-05-22 CL CL2017001301A patent/CL2017001301A1/es unknown
- 2017-06-06 CO CONC2017/0005624A patent/CO2017005624A2/es unknown
-
2019
- 2019-03-06 US US16/294,740 patent/US20190298790A1/en not_active Abandoned
-
2021
- 2021-09-27 US US17/449,031 patent/US20220143122A1/en not_active Abandoned
-
2024
- 2024-01-12 US US18/411,666 patent/US20240299480A1/en not_active Abandoned
- 2024-11-25 US US18/958,788 patent/US20250228913A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO2017005624A2 (es) | Composiciones oftálmicas estabilizadas de omega 3 | |
| BR112019006160A2 (pt) | composições e métodos para o tratamento das condições oftálmicas | |
| MX389460B (es) | Composiciones y metodos de uso en nintedanib para tratar enfermedades oculares con neovascularizacion anormal. | |
| MX2020001340A (es) | Modelos celulares y terapias para enfermedades oculares. | |
| ECSP19044183A (es) | (aza)indol-, benzotiofen, y benzofuran-3-sulfonamidas | |
| CL2018001478A1 (es) | Agonistas del receptor de apelina y métodos de uso | |
| MX2017014375A (es) | Moduladores del ccr2. | |
| CO2017004715A2 (es) | Métodos y formulaciones para tratar enfermedades vasculares de los ojos | |
| MX2018003388A (es) | Agonistas del receptor farnesoide x y usos de los mismos. | |
| MX2017016517A (es) | Composiciones estables al almacenamiento y metodos para el tratamiento de errores de refraccion del ojo. | |
| WO2016040775A3 (en) | Apparatus and methods for identifying and evaluating bright spot indications observed through optical coherence tomography | |
| MX388380B (es) | Composiciones para usarse en el incremento de los niveles de glóbulos rojos y el tratamiento de enfermedad de células falciformes. | |
| AR091237A1 (es) | Composiciones que comprenden un aptamero anti factor de crecimiento derivado de plaquetas (anti-pdgf) y un antagonista de factor de crecimiento de endotelio vascular (vegf) | |
| CR20190239A (es) | Inhibidores de la magl | |
| AR096478A1 (es) | Composiciones para el tratamiento de superficie que comprenden tintes fotocromáticos | |
| EA201992170A1 (ru) | Модуляторы экспрессии pcsk9 | |
| DOP2018000219A (es) | Anticuerpos anti-factor bb del complemento y usos de estos | |
| CO2018005393A2 (es) | Anticuerpos anti-htra1 y métodos de uso de los mismos | |
| AR100231A1 (es) | Composiciones para el cuidado de las telas que comprenden polímeros de poliuretano, poliurea y/o poliuretanourea | |
| MY193650A (en) | Extracellular matrix compositions | |
| CO2018007237A2 (es) | Reguladores del cftr y métodos para su uso | |
| MX392383B (es) | Metodos para tratar afecciones oculares. | |
| BR112017011685A2 (pt) | composições compreendendo 15-hepe e métodos de tratamento ou prevenção da fibrose usando as mesmas | |
| MX377022B (es) | Composiciones de lágrimas artificiales. | |
| EA201790391A1 (ru) | Композиции для ингибирования воспаления у субъекта с повреждением спинного мозга и способы их применения |