CN2551208Y - Ultrasonic focusing knife for treating tumour - Google Patents
Ultrasonic focusing knife for treating tumour Download PDFInfo
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- CN2551208Y CN2551208Y CN 02222533 CN02222533U CN2551208Y CN 2551208 Y CN2551208 Y CN 2551208Y CN 02222533 CN02222533 CN 02222533 CN 02222533 U CN02222533 U CN 02222533U CN 2551208 Y CN2551208 Y CN 2551208Y
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- therapy head
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 23
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 238000002604 ultrasonography Methods 0.000 claims abstract description 6
- 230000007246 mechanism Effects 0.000 claims abstract description 5
- 238000002648 combination therapy Methods 0.000 claims description 31
- 239000000523 sample Substances 0.000 claims description 13
- 230000001225 therapeutic effect Effects 0.000 claims description 13
- 238000003745 diagnosis Methods 0.000 claims description 11
- 239000008280 blood Substances 0.000 claims description 10
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- 238000012544 monitoring process Methods 0.000 abstract description 6
- 238000002560 therapeutic procedure Methods 0.000 abstract description 6
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- 230000008901 benefit Effects 0.000 abstract description 2
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- 238000000034 method Methods 0.000 description 5
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- 210000004881 tumor cell Anatomy 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
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- 230000003252 repetitive effect Effects 0.000 description 3
- 206010028851 Necrosis Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
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- 230000004797 therapeutic response Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
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Abstract
The utility model provides a high intensity focused ultrasound for tumor therapy, belonging to a tumor therapy device utilizing the focused ultrasonic wave, which comprises a composite treatment head, an ultrasonic power source, a medium water treatment device, a B ultrasonic machine, a treatment bed, a main controller and an industrial control device. The utility model is characterized in that the composite treatment head is arranged on an arc arm of a five-dimensional movement mechanism and the arc arm is arranged in a water tank which is on the treatment bed; the composite treatment head is connected with the ultrasonic power source; the industrial control device is connected respectively with the five-dimensional movement mechanism and the ultrasonic power source by the main controller; the B ultrasonic machine is connected with the industrial control device by a video capture card. The utility model has the advantages of precise focusing, good form of the focus, high power and sound intensity, a plurality of forms of wave field, intuitive and real-time monitoring on the condition of the body surface of the treated area, fast, intuitive and qualitative judgment on the treatment effect.
Description
1. technical field
This utility model relates to a kind of focus ultrasonic knife for treating cancers that utilizes ultrasound wave that tumor is scanned and treats.
2. background technology
Modern medicine is discovered, tumor cell ratio normal cell poor heat resistance, between 42.5～45 degree, inner tumour cell death in 30 minutes, about 3 seconds kill tumor cells of 60 ℃ of needs, but and 100 ℃ only need 0.1 second just kill tumor cell.Utilize this characteristics, (HighIntensity Ficused Ultrasoelnd---HIFU) technology treatment tumor has become domestic and international development trend to adopt high intensity focused ultrasound.Ultrasonic beam is at the human body inner focusing, the high intensity ultrasonic energy at focus place is acted in the human body inner target tissue (tumor), (irradiation of 0.5s～5s) is at the generation of target tissue place high-temperature effect, mechanical effect and cavitation effect through high strength supersonic (every square centimeter can the reach myriawatt) short time.Make tumor tissues produce coagulation necrosis, lose propagation, infiltration and transfer ability, thereby reach the purpose of treatment tumor.There are some shortcomings in the existing product of HIFU technology treatment tumor that utilizes: 1. the ultrasonic maximum sound intensity in the burnt territory, the burnt territory of existing product big (major and minor axis bigger) is lower than 15000W/cm
2, therapeutic effect is poor like this, treatment time is long.2. adopt diagnosis of B ultrasonic two dimension and two-dimentional Therapeutic Method, can not intactly judge focus character and structure and treatment.3. existing product does not all have real time monitoring by the function of area for treatment body surface, burn takes place easily and cause the therapentic part deviation because of the patient body position changes.4. existing product all can not be judged therapeutic effect fast, intuitively, qualitatively
The purpose of this utility model is intended to overcome the shortcoming of prior art, provide that little, the high-power sound intensity in a kind of burnt territory, burnt territory form are good, 3 D stereo diagnosis and treatment, location accurately, monitoring, the reliable and easy to operate focus ultrasonic knife for treating cancers of working stability in real time.
3. summary of the invention
The purpose of this utility model is to realize like this, a kind of focus ultrasonic knife for treating cancers is made up of combined therapy head, ultrasonic power source, WATER AS FLOW MEDIUM blood processor, B ultrasonic machine, therapeutic bed, master controller and industrial computer, it is characterized in that: described combined therapy head is installed on the arched arm of five dimension motions; The middle part of therapeutic bed is useful on the water tank of depositing WATER AS FLOW MEDIUM, and the WATER AS FLOW MEDIUM blood processor links to each other with water tank, and arched arm is placed in the water tank; The combined therapy head links to each other with the ultrasonic power source; Industrial computer links to each other with five dimension motions, ultrasonic power source respectively by master controller, and the B ultrasonic machine is by video acquisition card connection industrial computer.
Five dimension motions of described five dimension motions are made up of X, Y, Z, θ, γ motion: the motion of X, Y, Z is the same: servomotor is sent to ball screw by decelerator, ball screw drives supporting plate and moves on guide rail, rotary encoder is connected with ball screw, and X, Y, three motion stacks of Z just constitute the three-dimensional cartesian coordinate system motion; Servomotor is by the synchronous band on the decelerator connection arched arm, band is fixed with slide block synchronously, the combined therapy head is fixed on and makes the combined therapy head move and keep forming at grade with the Y coordinate along arched arm on the slide block, the γ coordinate motion is finished the arcuate movement of two-dimensional cross-section in the Y coordinate plane, and arched arm is fixed on X, Y, three single motion stacks of Z constitute on the three-dimensional motion device; Pneumatic cylinders drives the combined therapy head by connecting rod and rotates around self axle center and form the θ coordinate motion, finishes the conversion of two vertical mutually and two-dimensional axisymmetric diagnosis faces; The control of five dimension motions is by master controller motor message to be sent to front controller by industrial computer, front controller control servo motion mechanism drives the motion of combined therapy head, motion detector feeds back to front controller with detected position signalling, feed back to industrial computer by master controller again, realize the closed loop control of motion.
Described ultrasonic power source is: the principal oscillation device of 0.8MHz～1.7MHz connects 12 tunnel enable switch and connects intermediate level circuit and amplify, again by isolating transformer driving power amplifier, deliver to energy transducer through impedance matching circuit through power detection, energy transducer transmitting power ultrasound wave by the high-frequency electrical energy after the power amplifier amplification; 12 tunnel enable switch connect the phase sequence generator, and the phase sequence generator connects PC I/O interface, and PC I/O interface connects power amplifier by the scalable dc source, and PC I/O interface connects power-sensing circuit by indicator;
Described combined therapy head comprises acoustic lens, and the plane of acoustic lens is fixed with 8～20 piezoelectric transducers; There is protruding configuration Ultrasonic-B probe at the place, hole at acoustic lens center; Sheath is fixed with acoustic lens and Ultrasonic-B probe sealing positioning and fixing adjusting rubber cushion and is used for fixing Ultrasonic-B probe on the sheath bottom.
Described arched arm is equipped with the underwater photography head.
Under industrial computer control, ultrasonic power source, B ultrasonic machine, five dimension motions are continuous real time operations.
This utility model is compared with prior art has following major advantage: the combined therapy head has vernier focusing, good, the high-power sound intensity of focus form, multiple wave field form, and focus accurately is positioned on the B ultrasonic diagnosis face perpendicular bisector, and the relative position height is fixed; Adopt protruding configuration Ultrasonic-B probe to make B ultrasonic picture quality not be subjected to the influence of acoustic lens; The underwater camera head is installed, and real time monitoring is effectively avoided taking place burn and is caused the therapentic part deviation because of the patient body position changes by area for treatment body surface situation intuitively; Utilize the working method of θ coordinate can finish the conversion of two vertical mutually and axial symmetry two two-dimentional diagnosis faces easily; Adopt digital image processing techniques, handle in real time and draw a diagram, make the operator can judge therapeutic effect fast, intuitively, qualitatively treating forward and backward image.
4. description of drawings
Fig. 1 is the theory diagram of this utility model embodiment;
Fig. 2 is the structural representation that five of this utility model embodiment ties up X, Y, Z in the motions;
Fig. 3 is the structural representation that five of this utility model embodiment ties up γ in the motions;
Fig. 4 is the structural representation that five of this utility model embodiment ties up θ in the motions;
Fig. 5 is the combined therapy header structure sketch map of this utility model embodiment;
Fig. 6 is an acoustic lens structural representation in the combined therapy head of this utility model embodiment;
Fig. 7 is the ultrasonic power source schematic diagram of this utility model embodiment;
Fig. 8 is the operating process block diagram of this utility model embodiment.
5. the specific embodiment
As shown in Figure 1: a kind of focus ultrasonic knife for treating cancers is made up of combined therapy head, ultrasonic power source, WATER AS FLOW MEDIUM blood processor, B ultrasonic machine, therapeutic bed, master controller and industrial computer.Industrial computer is the control maincenter of focus ultrasonic knife for treating cancers, adopt Pentium 3 above processors, its I/O is configured to DMC300 motion control card, PC-6407 on-off output card, PC-6405 switching value input card, PC-6320 A/D card and MVPCI image collection card.The B ultrasonic machine adopts the CX-900C type, and the WATER AS FLOW MEDIUM blood processor adopts the CZ901-6 type.
Combined therapy head 12 is installed on the arched arm 9 of five dimension motions; The middle part of therapeutic bed is useful on the water tank of depositing WATER AS FLOW MEDIUM, and the WATER AS FLOW MEDIUM blood processor links to each other with water tank, and arched arm is placed in the water tank; The combined therapy head links to each other with the ultrasonic power source; Industrial computer links to each other with five dimension motions, ultrasonic power source respectively by master controller, and the B ultrasonic machine is by video acquisition card connection industrial computer.
Described combined therapy head comprises acoustic lens 15, is adhesively fixed with equally distributed 8～12 piezoelectric energy-conversion devices 16 by seccotine on the plane of acoustic lens 15; The power supply of piezoelectric energy-conversion device is provided by the ultrasonic power source; There is protruding configuration Ultrasonic-B probe 17 at the place, hole at acoustic lens 15 centers; Sheath 18 is the sealing of acoustic lens and Ultrasonic-B probe, is fixed with positioning and fixing on sheath 18 bottoms and regulates rubber cushion 19 and be used for fixing and regulate Ultrasonic-B probe 17; 8～12 piezoelectric energy-conversion devices are according to the high-frequency electrical energy energy size and the phase sequence that apply, the multiple power ultrasonic format of field of generation capable of being combined; Adopt protruding configuration Ultrasonic-B probe, acoustic lens is to the not influence of B ultrasonic image quality, and when the combined therapy head was to oncotherapy, Ultrasonic-B probe is the image of scanning collection tumor simultaneously, is sent to industrial computer like this, and the operator can see the situation of treatment intuitively.
Combined therapy head technical parameter is as follows:
Burnt territory: X minor axis≤2.6mm, Y minor axis≤2.6mm, Z major axis≤8.0mm;
The maximum sound intensity: the maximum sound intensity 〉=20KW/cm in focus maximum cross section
2
Focal plane height: 55mm, 95mm, 115mm, 165mm, 140mm;
Power ultrasonic format of field: continuous wave, impulse wave (dutycycle 1%～99%), rotation wave (6 kinds of forms).
Five dimension motions of five dimension motions are made up of X, Y, Z, θ, γ motion: the motion of X, Y, Z is the same: servomotor 1 is sent to ball screw 3 by decelerator 2, ball screw 3 drives supporting plate 4 and moves on guide rail 5, rotary encoder 6 is connected with ball screw (3), and X, Y, three motion stacks of Z just constitute the three-dimensional cartesian coordinate system motion; Servomotor 7 connects by decelerator 8 is with 10 on the arched arms 9 synchronously, be with 10 to be fixed with slide block 11 synchronously, combined therapy head 12 is fixed on and makes combined therapy head 12 keep forming at grade along arched arm (9) motion and with the Y coordinate on the slide block 11, the γ coordinate motion is finished the arcuate movement of two-dimensional cross-section in the Y coordinate plane, and arched arm 9 is fixed on X, Y, three single motion stacks of Z constitute on the three-dimensional motion device; Pneumatic cylinders 13 drives combined therapy heads 12 by connecting rod 14 and rotates around self axle center and form the θ coordinate motion, finishes the conversion of two vertical mutually and two-dimensional axisymmetric diagnosis faces; The three dimensional constitution of diagnosis and treatment can be finished so easily, thereby focus character and structure and treatment can be intactly judged.
The control of five dimension motions is by master controller motor message to be sent to front controller by industrial computer, front controller control servo motion mechanism drives the motion of combined therapy head, motion detector feeds back to front controller with detected position signalling, feed back to industrial computer by master controller again, realize the closed loop control of motion.
Arched arm 9 is equipped with underwater camera head 20, and real time monitoring is effectively avoided taking place burn and caused the therapentic part deviation because of the patient body position changes by area for treatment body surface situation so intuitively.
The ultrasonic power source is as shown in Figure 7: the principal oscillation device of 0.8MHz～1.7MHz connects 12 tunnel enable switch, amplify through intermediate level circuit, again by isolating transformer driving power amplifier, deliver to energy transducer through impedance matching circuit through power detection, energy transducer transmitting power ultrasound wave by the high-frequency electrical energy after the power amplifier amplification.12 tunnel enable switch connect the phase sequence generator, and the phase sequence generator connects PC I/O interface, and PC I/O interface connects power amplifier by the scalable dc source, and PC I/O interface connects power-sensing circuit by indicator.The principal oscillation device produces an operating frequency voltage that mates with energy transducer, delivering to intermediate level circuit through enable switch amplifies, by isolating transformer driving power amplifier, the high-frequency electrical energy after the amplification is delivered to through impedance matching circuit and is made energy transducer launch power ultrasonic again; Industrial computer is regulated the output voltage values of dc source automatically through the I/O interface, thereby has regulated high-frequency electrical energy, has also just regulated the ultrasonic power value of emission.
Under industrial computer control, what ultrasonic power source, B ultrasonic machine, five were tieed up motions is the closed loop real time operation.
This utility model adopts following diagnostic mode:
1. adopt the three-dimensional arrangement mode of B ultrasonic two dimension diagnosis plane and Ultrasonic-B probe half-twist.
2. underwater camera and CT or MRI picture are assisted appearance level diagnosis mode.
This utility model adopts following therapeutic modality:
1. in treatment region, can carry out single-point or multiple spot, single or multiple repetitive therapy.
2. in treatment region, can carry out single line or multi-thread, single or multiple repetitive therapy.
3. in treatment region, can carry out point, the line of camber line, the single or multiple repetitive therapy.
Capable of being combined use of these three kinds of modes by putting line, constitutes face by multi-thread, constitutes solid by face.
Work process of the present utility model as shown in Figure 8 starts ultrasonic power source, WATER AS FLOW MEDIUM blood processor, five dimension motions.The WATER AS FLOW MEDIUM blood processor is handled the back with WATER AS FLOW MEDIUM and is warmed to about 25 ℃, and WATER AS FLOW MEDIUM poured in water tank reaches the treatment desired height.
Utilize the diagnosis of underwater photography head and B ultrasonic with patient's positioning and fixing, industrial computer control five dimension motions drive the combined therapy head patient's lesions position are diagnosed, determine therapeutic scheme and treatment parameter according to diagnostic result, automatically treat by industrial computer, underwater photography head and monitor real time monitoring patient body position and therapeutic response situation, and gather the B ultrasonic image in real time and to treating forward and backward image, treatment position and relevant parameter are preserved and playback, carry out the gray scale comparison of treatment position in real time and treatment aspect are carried out the analysis of therapeutic effect.After treatment finishes, judge therapeutic effect, determine that next step is the repetition said process, still finish treatment according to forward and backward grey scale transformation change curve of treatment and blood circumstance.
Claims (7)
1. a focus ultrasonic knife for treating cancers is made up of combined therapy head, ultrasonic power source, WATER AS FLOW MEDIUM blood processor, B ultrasonic machine, therapeutic bed, master controller and industrial computer, it is characterized in that: the combined therapy head is installed on the arched arm of five dimension motions; The middle part of therapeutic bed is useful on the water tank of depositing WATER AS FLOW MEDIUM, and the WATER AS FLOW MEDIUM blood processor links to each other with water tank, and arched arm is placed in the water tank; The combined therapy head links to each other with the ultrasonic power source; Industrial computer links to each other with five dimension motions, ultrasonic power source respectively by master controller, and the B ultrasonic machine is by video acquisition card connection industrial computer.
2. focus ultrasonic knife for treating cancers as claimed in claim 1, it is characterized in that: five dimension motions of described five dimension motions are made up of X, Y, Z, θ, γ motion, the motion of X, Y, Z is the same: servomotor (1) is sent to ball screw (3) by decelerator (2), ball screw (3) drives supporting plate (4) and goes up motion at guide rail (5), rotary encoder (6) is connected with ball screw (3), and X, Y, three motion stacks of Z just constitute the three-dimensional cartesian coordinate system motion; Servomotor (7) is by the synchronous band (10) on decelerator (8) the connection arched arm (9), band (10) is fixed with slide block (11) synchronously, combined therapy head (12) is fixed on and makes combined therapy head (12) keep forming at grade along arched arm (9) motion and with the Y coordinate on the slide block (11), the γ coordinate motion is finished the arcuate movement of two-dimensional cross-section in the Y coordinate plane, and arched arm (9) is fixed on X, Y, three single motion stacks of Z constitute on the three-dimensional motion device; Pneumatic cylinders (13) drives combined therapy head (12) by connecting rod (14) and rotates around self axle center and form the θ coordinate motion, finishes the conversion of two vertical mutually and two-dimensional axisymmetric diagnosis faces; The control of five dimension motions is by master controller motor message to be sent to front controller by industrial computer, front controller control servo motion mechanism drives the motion of combined therapy head, motion detector feeds back to front controller with detected position signalling, feed back to industrial computer by master controller again, realize the closed loop control of motion.
3. focus ultrasonic knife for treating cancers as claimed in claim 1, it is characterized in that: described ultrasonic power source is: the principal oscillation device of 0.8MHz～1.7MHz connects 12 tunnel enable switch, amplify through intermediate level circuit, again by isolating transformer driving power amplifier, deliver to energy transducer through impedance matching circuit through power detection, energy transducer transmitting power ultrasound wave by the high-frequency electrical energy after the power amplifier amplification; 12 tunnel enable switch connect the phase sequence generator, and the phase sequence generator connects PC I/O interface, and PC I/O interface connects power amplifier by the scalable dc source, and PC I/O interface connects power-sensing circuit by indicator.
4. focus ultrasonic knife for treating cancers as claimed in claim 1 is characterized in that: described combined therapy head (12) comprises acoustic lens (15), and the plane of acoustic lens (15) is fixed with 8～20 piezoelectric transducers (16); There is protruding configuration Ultrasonic-B probe (17) at the place, hole at acoustic lens (15) center; Sheath (18) is fixed with acoustic lens and Ultrasonic-B probe sealing positioning and fixing adjusting rubber cushion (19) and is used for fixing Ultrasonic-B probe (17) on sheath (18) inside.
5. focus ultrasonic knife for treating cancers as claimed in claim 1 is characterized in that: described arched arm (9) is equipped with underwater photography head (20).
6. focus ultrasonic knife for treating cancers as claimed in claim 1 is characterized in that: under the control of industrial computer, ultrasonic power source, B ultrasonic machine, five dimension motions are the real-time work of closed loop.
7. focus ultrasonic knife for treating cancers as claimed in claim 1 is characterized in that: burnt territory X minor axis≤2.6mm, Y minor axis≤2.6mm, Z major axis≤8.0mm that described combined therapy capitiform becomes, the maximum sound intensity 〉=20KW/cm in focus maximum cross section
2, positioning accuracy ± 1mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02222533 CN2551208Y (en) | 2002-05-10 | 2002-05-10 | Ultrasonic focusing knife for treating tumour |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02222533 CN2551208Y (en) | 2002-05-10 | 2002-05-10 | Ultrasonic focusing knife for treating tumour |
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| CN2551208Y true CN2551208Y (en) | 2003-05-21 |
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| CN 02222533 Expired - Fee Related CN2551208Y (en) | 2002-05-10 | 2002-05-10 | Ultrasonic focusing knife for treating tumour |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006072196A1 (en) * | 2005-01-10 | 2006-07-13 | Chongqing Haifu(Hifu)Technology Co., Ltd | High intensity focused ultrasound therapeutic apparatus and method |
| CN100430024C (en) * | 2004-12-24 | 2008-11-05 | 重庆融海超声医学工程研究中心有限公司 | Image monitoring device for skin and subcutaneous tissue damage |
| CN105392529A (en) * | 2013-03-28 | 2016-03-09 | 华盛顿大学商业化中心 | Focused ultrasound apparatus and methods of use |
| CN112546466A (en) * | 2020-12-24 | 2021-03-26 | 重庆海扶医疗科技股份有限公司 | Device for monitoring and treating breast tumor |
-
2002
- 2002-05-10 CN CN 02222533 patent/CN2551208Y/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100430024C (en) * | 2004-12-24 | 2008-11-05 | 重庆融海超声医学工程研究中心有限公司 | Image monitoring device for skin and subcutaneous tissue damage |
| WO2006072196A1 (en) * | 2005-01-10 | 2006-07-13 | Chongqing Haifu(Hifu)Technology Co., Ltd | High intensity focused ultrasound therapeutic apparatus and method |
| RU2359721C2 (en) * | 2005-01-10 | 2009-06-27 | Чонгцинг Хайфу(Хифу)Текнолоджи Ко., Лтд | Method and device for focused ultrasonic therapy of high intensity |
| AU2005324269B2 (en) * | 2005-01-10 | 2009-09-10 | Chongqing Haifu Medical Technology Co., Ltd. | Method and apparatus for high-intensity focused ultrasound therapy |
| CN105392529A (en) * | 2013-03-28 | 2016-03-09 | 华盛顿大学商业化中心 | Focused ultrasound apparatus and methods of use |
| US10350439B2 (en) | 2013-03-28 | 2019-07-16 | University Of Washington Through Its Center For Commercialization | Focused ultrasound apparatus and methods of use |
| CN105392529B (en) * | 2013-03-28 | 2020-03-17 | 华盛顿大学商业化中心 | Focused ultrasound device and method of use |
| CN112546466A (en) * | 2020-12-24 | 2021-03-26 | 重庆海扶医疗科技股份有限公司 | Device for monitoring and treating breast tumor |
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