CN216171903U - Passive micro mixer with spatial structure - Google Patents
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- CN216171903U CN216171903U CN202122360860.4U CN202122360860U CN216171903U CN 216171903 U CN216171903 U CN 216171903U CN 202122360860 U CN202122360860 U CN 202122360860U CN 216171903 U CN216171903 U CN 216171903U
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Abstract
The utility model discloses a passive micro mixer with a space structure, which comprises a plurality of input devices, a mixing device and an output device. The input device comprises an input device shell and an input flow channel; the mixing device comprises a mixing device shell, an inlet flow channel, a mixing flow channel and a mixing mechanism arranged in the mixing flow channel; the mixing mechanism comprises a space mixing mechanism and a boss mixing mechanism; the output device comprises an output device shell and an output flow channel. The utility model realizes the aim of uniformly mixing the solution by twisting and mixing and increasing the vortex, and quickly and efficiently obtains the solution with good mixing degree.
Description
Technical Field
The utility model relates to the technical field of microfluid mixing, in particular to a passive micromixer with a space structure.
Background
Micromixers are key components for performing chemical or biological reactions and detecting analytes in microfluidic or lab-on-a-chip devices. Micromixers are widely used in microfluidic systems to produce homogeneous mixtures for chemical reactions, chemical synthesis, purification, polymerization, sample preconcentration, deoxyribonucleic acid digestion, and nanomedicine. In such applications, mixing is critical, as non-uniform mixing negatively impacts the properties of the final product. Laminar flow occurs when the reynolds number (Re) is below 2000, causing diffusion to be the driving mechanism for mixing. Thus, the mixing of the fluids is affected by the interfacial area and diffusion length between the fluids. The traditional approach to achieve efficient mixing at low Re values is to significantly increase the length of the microfluidic channel, however, this is difficult to achieve in small volume microfluidic chips. In microfluidic devices, mixing is often limited by diffusion, which is a relatively long time, resulting in inefficient subsequent analysis. For this reason, improvement of mixing efficiency has been the focus of various studies.
Devices for enhancing mixing performance in microchannels can be divided into two broad categories, active mixers and passive mixers. Active mixers are more often preferred over passive micromixers due to the additional equipment required to improve mixing efficiency, complexity and cost of operation. The passive micro mixer mainly completes mixing action through diffusion and chaotic flow, and common structures comprise a T-shaped structure, a Y-shaped structure, a zigzag structure, a spiral structure and the like. However, the mixing efficiency of most passive micromixers is still limited by the size of the device dimensions.
Therefore, it is very important to design and manufacture a micro mixer with small volume, simple structure, convenient manufacture and high mixing efficiency to realize rapid and uniform liquid mixing.
SUMMERY OF THE UTILITY MODEL
The present invention provides a passive micro mixer with a spatial structure, which can achieve the purpose of uniformly mixing a solution by twisting and increasing a vortex, and quickly and efficiently obtain a solution with a good mixing degree.
In order to solve the technical problems, the utility model adopts the technical scheme that:
a passive micromixer with a spatial structure comprises a plurality of input devices, a mixing device and an output device.
The input device includes an input device housing and an input flow passage.
The mixing device comprises a mixing device shell, an inlet flow channel, a mixing flow channel and a mixing mechanism arranged in the mixing flow channel.
The output device comprises an output device shell and an output flow channel.
The input device shell is connected with one end of the mixing device shell; the other end of the mixing device shell is connected with the output device shell.
The input flow channel is arranged in the input device shell and penetrates through the input device shell; the output flow channel is arranged in the output device shell and penetrates through the output device shell.
The input flow channel is connected with one end of the inlet flow channel; the other end of the inlet flow passage is connected with one end of the mixing flow passage; the other end of the mixing flow passage is connected with an output flow passage.
One end of the inlet flow passage is provided with a plurality of branched flow passages which are respectively and correspondingly connected with the input flow passages of a plurality of input devices; the plurality of branch channels are converged to a main channel and communicated with the mixing channel.
The mixing mechanism comprises a space mixing mechanism and a boss mixing mechanism.
One end of the space mixing mechanism is connected with a main runner of the inlet runner, the inlet runner is branched into a plurality of branched runners, and the branched runners are converged into the main runner at the other end of the space mixing mechanism and connected to the boss mixing mechanism.
The plane of the plurality of branched runners of the spatial mixing mechanism is vertical to the plane of the plurality of branched runners of the inlet runner.
The boss mixing mechanism comprises a plurality of asymmetrical herringbone bosses.
As a further preferred aspect of the present invention, the input device further includes a rib for reinforcement; the ribbed plate is connected with the side surface of the input device shell; ribbed plates are uniformly distributed on input device shells of the plurality of input devices.
As a further preferred aspect of the utility model, the output device also comprises ribs for reinforcement; the ribbed plate is connected with the side surface of the output device shell.
As a further preferred aspect of the present invention, the included angle between the long side and the short side of the herringbone boss of the boss mixing mechanism is 90 °, and the length ratio of the long side to the short side is 2: 1.
As a further preferred aspect of the present invention, the long and short sides of the herringbone boss of the boss mixing mechanism are connected with the side wall of the mixing flow channel in the liquid coming direction at an angle of 45 °.
As a further preferred aspect of the present invention, the herringbone bosses of the boss mixing mechanism are arranged in groups, each group includes 9 individual herringbone bosses, and the arrangement directions of the long edges and the short edges of the herringbone bosses of adjacent groups are opposite.
It is further preferred for the present invention that the distance between adjacent sets of chevron-shaped bosses is greater than the distance between chevron-shaped bosses within a set.
The utility model has the following beneficial effects:
1. compared with an active micro mixer, the device has the advantages of simple structure, small volume and convenient operation, and does not need an additional device to drive the micro mixer
2. Compared with the existing passive micro mixer, the utility model has two different mixing modes, the spatial mixing module adopts a mode of changing the fluid movement direction to achieve the aim of quickly mixing the solution, even if the solution with low Reynolds number or poor compatibility has better mixing effect, the boss mixing module generates additional vortex on the cross section of the fluid through an asymmetric herringbone boss, the transverse movement of the fluid is increased, and the solution can be better mixed and more uniformly mixed.
Drawings
Fig. 1 is a schematic structural diagram of a passive micromixer with a spatial structure according to the present invention.
Fig. 2 is a schematic diagram of an input device of a passive micro mixer with a spatial structure according to the present invention.
Fig. 3 is a schematic diagram of an output device of a passive micromixer with a spatial structure according to the present invention.
Fig. 4 is a schematic view of an inlet channel of a passive micro mixer with a spatial structure according to the present invention.
Fig. 5 is a schematic diagram of a mixing mechanism of a passive micromixer with a spatial structure according to the present invention.
Fig. 6 is a schematic diagram of a spatial mixing mechanism of a passive micromixer with a spatial structure according to the present invention.
Fig. 7 is a schematic diagram of a boss mixing mechanism of a passive micro mixer with a spatial structure according to the present invention.
Fig. 8a and 8b are schematic views of the vortex flow of the boss mixing mechanism of a passive micromixer having a spatial structure according to the present invention.
Among them are:
10. an input device; 11 an input device housing; 12. an input flow channel; 13. a rib plate;
20. a mixing device; 21. a mixing device housing; 22. an inlet flow passage; 23. a mixing flow channel; 24. a mixing mechanism; 241. a spatial mixing mechanism; 242. a boss mixing mechanism; 2421. a herringbone boss;
30. an output device; 31. an output device housing; 32. and (4) outputting the flow channel.
Detailed Description
In the description of the present invention, it is to be understood that the terms "left side", "right side", "upper part", "lower part", etc., indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and that "first", "second", etc., do not represent an important degree of the component parts, and thus are not to be construed as limiting the present invention. The specific dimensions used in the present example are only for illustrating the technical solution and do not limit the scope of protection of the present invention.
The present invention will be described in further detail with reference to the accompanying drawings and specific preferred embodiments.
As shown in fig. 1, a passive micromixer with a spatial structure includes a plurality of input devices 10, a mixing device 20, and an output device 30.
As shown in fig. 2, the input device 10 includes an input device housing 11 and an input flow channel 12.
The mixing device 20 comprises a mixing device housing 21, an inlet flow channel 22, a mixing flow channel 23 and a mixing mechanism 24 arranged in the mixing flow channel 23.
As shown in fig. 3, the output device 30 includes an output device housing 31 and an output flow passage 32.
The input device shell 11 is connected with one end of the mixing device shell 21; the other end of the mixing device shell 21 is connected with an output device shell 31.
The input flow channel 12 is arranged in the input device shell 11 and penetrates through the input device shell 11; the output flow channel 32 is disposed in the output device housing 31 and penetrates through the output device housing 31.
The input device 10 further comprises a rib plate 13 for reinforcement; the rib plate 13 is connected with the side surface of the input device shell 11; ribbed plates 13 are uniformly distributed on the input device shells 11 of the plurality of input devices 10.
The output device 30 also comprises ribs 13 for reinforcement; the rib 13 is connected to the side of the output housing 31.
The input flow channel 12 is connected with one end of the inlet flow channel 22; the other end of the inlet flow passage 22 is connected with one end of a mixing flow passage 23; the other end of the mixing flow channel 23 is connected with an output flow channel 32.
As shown in fig. 4, one end of the inlet channel 22 is provided with a plurality of branched channels, which are respectively connected to the input channels 12 of the plurality of input devices 10; the plurality of branch channels converge to a main channel, which communicates with the mixing channel 23.
As shown in fig. 5, the mixing mechanism 24 includes a spatial mixing mechanism 241 and a boss mixing mechanism 242.
As shown in fig. 6, one end of the spatial mixing mechanism 241 is connected to the main channel of the inlet channel 22, and the end is branched into a plurality of branched channels, and the plurality of branched channels are collected into a main channel at the other end of the spatial mixing mechanism 241 and connected to the boss mixing mechanism 242.
The planes of the branched flow paths of the spatial mixing mechanism 241 are perpendicular to the planes of the branched flow paths of the inlet flow path 22.
As shown in fig. 7, the boss mixing mechanism 242 includes a plurality of asymmetric chevron bosses 2421.
The included angle of the long side and the short side of the herringbone boss 2421 of the boss mixing mechanism 242 is 90 degrees, and the length ratio of the long side and the short side is 2: 1.
The long and short sides of the herringbone boss 2421 of the boss mixing mechanism 242 are connected with the side wall of the mixing flow channel 23 in the liquid incoming direction at an angle of 45 degrees.
The herringbone bosses 2421 of the boss mixing mechanism 242 are arranged in groups, each group comprises 9 herringbone bosses 2421, and the arrangement directions of the long edges and the short edges of the herringbone bosses 2421 of the adjacent groups are opposite.
The distance between adjacent sets of chevron shaped bosses 2421 is greater than the distance between chevron shaped bosses 2421 within a set.
Preferred embodiment 1
The mixing device housing 21 is formed to be thick at both ends and thin at the center, which facilitates observation of the mixing of the solution in the mixing channel 23. The mixing device housing 21 has a length of 16mm and a width of 4mm, the thicker portions on both sides having a width of 1mm and a height of 1.6mm, and the thinner portion in the middle having a height of 0.8 mm.
Two branches of the inlet flow passage 22 are respectively connected with the input flow passage 12, and different solutions are combined into one strand and are conveyed into the solution mixing module. The two branch flow passages of the inlet flow passage 22 are 0.3mm high and 0.3mm wide, respectively, and the size of the merged flow passage is also 0.3mm high and 0.3mm wide.
The inlet of the space mixing mechanism 241 is a rectangular flow channel with the height of 0.5mm and the width of 0.3mm, the upper space flow channel and the lower space flow channel are rectangular flow channels with the height of 0.3mm and the width of 0.3mm, and the outlet of the space mixing mechanism 241 is a rectangular flow channel with the height of 0.3mm and the width of 0.5 mm. When the fluid enters the spatial mixing mechanism 241, the state of the fluid is distributed left and right, the spatial mixing mechanism 241 equally divides the solution into an upper part and a lower part by using a three-dimensional spatial structure, the fluid direction is changed by the spatial structure, and then the fluid is converged into a strand of solution left and right, so that the fluid is divided and recombined, and the rapid and efficient mixing of the solution is completed.
The fluid enters the boss mixing mechanism 242 through the spatial mixing mechanism 241.
The boss mixing mechanism 242 is formed by arranging a series of asymmetric herringbone bosses 2421 at the bottom of the flow channel, and the directions of two adjacent groups of herringbone bosses 2421 are opposite.
As shown in fig. 8a and 8b, by providing the asymmetrical chevron-shaped boss 2421, the fluid generates a transverse vortex in the cross-sectional direction of the mixing flow channel 23, which significantly enhances the mixing effect of the micro mixer.
The height of the herringbone boss 2421 is 0.1mm, the width of the herringbone boss 2421 is 0.1mm, the rotation angle of the herringbone boss 2421 is 90 degrees, the long side and the short side of the herringbone boss 2421 of the boss mixing mechanism 242 are connected with the side wall of the mixing flow channel 23 in the liquid coming direction at an angle of 45 degrees, and the length ratio of the long side to the short side is 2: 1.
The herringbone bosses 2421 of the boss mixing mechanism 242 are arranged in groups, each group comprises 9 herringbone bosses 2421, two adjacent herringbone bosses 2421 are spaced by 0.15mm, and the spacing between two adjacent herringbone bosses 242 is more than 0.2 mm.
Preferred embodiment 2
The input device shell 11 of the input device 10 is a rectangle with the length of 4mm and the side length of 0.8mm, the middle of the input device shell 11 is provided with an input flow channel 12 with a circular section shape, and the diameter of the flow channel is 0.3mm and is used for inputting solution.
The two branch flow paths of the inlet flow path 22 have a size of 0.3mm in diameter, and the diameter of the merged flow path is also 0.3 mm.
The entrance of the space mixing mechanism 241 is a square round section, the diameter of the round surface is 0.3mm, the height of the square surface is 0.5mm, the width of the square surface is 0.3mm, the divided branched flow channels are rectangular flow channels with the height of 0.3mm and the width of 0.3mm, and the exit of the space mixing mechanism 241 is a rectangular flow channel with the height of 0.5mm and the width of 0.5 mm.
The fluid enters the boss mixing mechanism 242 through the spatial mixing mechanism 241.
The size of the mixing flow channel 23 is 0.5mm in height and 0.5mm in width, and the height of the herringbone boss 2421 is 0.1mm and the width is 0.1 mm. The top and the bottom of the mixing channel 23 are uniformly provided with a boss mixing mechanism 242. The end of the mixing flow channel 23 connected with the output flow channel 32 is a square round section, the height of the square face is 0.5mm, the width of the square face is 0.5mm, and the diameter of the round face is 0.3 mm.
The height of the herringbone boss 2421 is 0.1mm, the width of the herringbone boss 2421 is 0.1mm, the rotation angle of the herringbone boss 2421 is 90 degrees, the long side and the short side of the herringbone boss 2421 of the boss mixing mechanism 242 are connected with the side wall of the mixing flow channel 23 in the liquid coming direction at an angle of 45 degrees, and the length ratio of the long side to the short side is 2: 1.
The herringbone bosses 2421 of the boss mixing mechanism 242 are arranged in groups, each group comprises 9 herringbone bosses 2421, two adjacent herringbone bosses 2421 are spaced by 0.15mm, and the spacing between two adjacent herringbone bosses 242 is more than 0.2 mm.
Although the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the details of the embodiments, and various equivalent modifications can be made within the technical spirit of the present invention, and the scope of the present invention is also within the scope of the present invention.
Claims (7)
1. A passive micromixer with a spatial structure, characterized in that: comprises a plurality of input devices (10), a mixing device (20) and an output device (30);
the input device (10) comprises an input device shell (11) and an input flow channel (12);
the mixing device (20) comprises a mixing device shell (21), an inlet flow channel (22), a mixing flow channel (23) and a mixing mechanism (24) arranged in the mixing flow channel (23);
the output device (30) comprises an output device shell (31) and an output flow channel (32);
the input device shell (11) is connected with one end of the mixing device shell (21); the other end of the mixing device shell (21) is connected with an output device shell (31);
the input flow channel (12) is arranged in the input device shell (11) and penetrates through the input device shell (11); the output flow channel (32) is arranged in the output device shell (31) and penetrates through the output device shell (31);
the input flow channel (12) is connected with one end of the inlet flow channel (22); the other end of the inlet flow passage (22) is connected with one end of the mixing flow passage (23); the other end of the mixing flow passage (23) is connected with an output flow passage (32);
one end of the inlet flow passage (22) is provided with a plurality of branched flow passages which are respectively and correspondingly connected with the input flow passages (12) of a plurality of input devices (10); a plurality of branch flow channels are converged to a main flow channel and communicated with the mixing flow channel (23);
the mixing mechanism (24) comprises a spatial mixing mechanism (241) and a boss mixing mechanism (242);
one end of the spatial mixing mechanism (241) is connected with a main flow channel of the inlet flow channel (22), the end is branched into a plurality of branched flow channels, and the plurality of branched flow channels are converged into one main flow channel at the other end of the spatial mixing mechanism (241) and are connected to the boss mixing mechanism (242);
the plane of the plurality of branched flow channels of the spatial mixing mechanism (241) is vertical to the plane of the plurality of branched flow channels of the inlet flow channel (22);
the boss mixing mechanism (242) includes a plurality of asymmetric chevron bosses (2421).
2. A passive micromixer with spatial structure in accordance with claim 1, characterized in that: the input device (10) further comprises a rib plate (13) for reinforcement; the rib plate (13) is connected with the side surface of the input device shell (11); ribbed plates (13) are uniformly distributed on input device shells (11) of the plurality of input devices (10).
3. A passive micromixer with spatial structure in accordance with claim 1, characterized in that: the output device (30) also comprises a rib plate (13) for reinforcing; the rib (13) is connected with the side surface of the output device shell (31).
4. A passive micromixer with spatial structure in accordance with claim 1, characterized in that: the included angle of the long side and the short side of the herringbone boss (2421) of the boss mixing mechanism (242) is 90 degrees, and the length ratio of the long side to the short side is 2: 1.
5. A passive micromixer with spatial structure in accordance with claim 1, characterized in that: the long side and the short side of the herringbone boss (2421) of the boss mixing mechanism (242) are connected with the side wall of the mixing flow channel (23) in the liquid coming direction at an angle of 45 degrees.
6. A passive micromixer with spatial structure in accordance with claim 1, characterized in that: the herringbone bosses (2421) of the boss mixing mechanism (242) are distributed in groups, each group comprises 9 personal-shaped bosses (2421), and the arrangement directions of the long edges and the short edges of the herringbone bosses (2421) of the adjacent groups are opposite.
7. A passive micromixer with spatial structure in accordance with claim 6, characterized by that: the distance between the herringbone bosses (2421) of the adjacent groups is larger than the distance between the herringbone bosses (2421) in the groups.
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| CN202122360860.4U CN216171903U (en) | 2021-09-28 | 2021-09-28 | Passive micro mixer with spatial structure |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116422389A (en) * | 2023-04-03 | 2023-07-14 | 宁波玄流智造有限公司 | A microfluidic chip and its application in the preparation of lipid nanoparticles |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116422389A (en) * | 2023-04-03 | 2023-07-14 | 宁波玄流智造有限公司 | A microfluidic chip and its application in the preparation of lipid nanoparticles |
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