CN201719266U - Mini device for sampling liquid of alimentary canal - Google Patents
Mini device for sampling liquid of alimentary canal Download PDFInfo
- Publication number
- CN201719266U CN201719266U CN2010202187999U CN201020218799U CN201719266U CN 201719266 U CN201719266 U CN 201719266U CN 2010202187999 U CN2010202187999 U CN 2010202187999U CN 201020218799 U CN201020218799 U CN 201020218799U CN 201719266 U CN201719266 U CN 201719266U
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- Prior art keywords
- sampling
- storehouse
- sampling storehouse
- injection port
- digestive tract
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- Expired - Lifetime
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- 238000005070 sampling Methods 0.000 title claims abstract description 114
- 239000007788 liquid Substances 0.000 title claims abstract description 22
- 238000002347 injection Methods 0.000 claims description 43
- 239000007924 injection Substances 0.000 claims description 43
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 23
- 239000002775 capsule Substances 0.000 claims description 15
- 238000006243 chemical reaction Methods 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 6
- 230000011664 signaling Effects 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 238000010521 absorption reaction Methods 0.000 claims description 3
- 210000001124 body fluid Anatomy 0.000 abstract description 6
- 239000010839 body fluid Substances 0.000 abstract description 4
- 239000011358 absorbing material Substances 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 238000005538 encapsulation Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
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- Endoscopes (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The utility model provides a mini device for sampling the liquid of the alimentary canal, which comprises a capsule-shaped shell, a power source and a wireless control mechanism. The mini device is characterized in that the shell is internally packed with a movable mechanism which consists of a mini electric machine and a sampling storehouse; the shell is provided with at least one or one set of sampling ports; the outer wall of the sampling storehouse is provided with at least one or one set of sample inlets which is or are communicated with the sampling storehouse; and the electric machine drives the sampling storehouse to move or/and rotate along the axial direction, so that sampling ports on the shell are contrapuntal with the sample inlets to realize the sampling or realize the blocking in a misplacing way. The mini device has the following advantages: the package is simple; the body fluid sampling storehouse is under the seal status before and after sampling the body liquid; a sampling mechanism is not influenced by the differential pressure of the alimentary canal; an absorbing material is used for sampling to guarantee that the acquired base body is the body fluid; and the sampling time can be controlled. When the sampling storehouse is divided into a plurality of independent cavities to be communicated with each sample inlet, the mini device can sample the different positions of the alimentary canal, can be independently packed without sample stringing, and can obtain more information.
Description
Technical field
This utility model relates to the insertion type medical apparatus and instruments, is specifically related to a kind of miniature digestive tract liquid sampler that capsule-type can be swallowed.
Background technology
Capsule endoscope is as a kind of visual diagnostic device of digestive tract disease, the application of having succeeded clinically, disclosed method for controlling duplex multi-channel intelligent capsule digestive tract endoscope such as CN1709196 and CN1647749 and duplex multipath intelligent capsule wireless endoscope system capsule endoscope system have been realized fixed point image acquisition and various control to capsule endoscope by wireless duplex communication mode.But owing to there not be the function of taking a sample, can not spot sampling, the diagnostic message of obtaining is single.
Chinese patent ZL03232994.6 discloses a kind of miniature digestive tract sampling apparatus, by being positioned at capsule shape device two ends, be subjected to the stretching of two springs of magnet control to drive sampling interior capsul of small opening and relatively moving of external seal shell respectively, finish the para-position and the dislocation of the opinion of sampling small opening, by the para-position realization sampling of inside and outside capsul up-sampling small opening.But there is following deficiency in this device:
(1) encapsulation is very difficult;
(2) air-tightness;
(3) because the pressure in the digestive tract changes constantly, this device can not guarantee that the liquid that can not that is collected is subjected to the influence that outside pressure changes after sampling finishes;
(4) owing in the digestive tract a lot of gases are arranged, only collect most of gas probably;
(5) sampling time is uncontrollable;
(6) have only a sampling storehouse, can only adopt sample one time.
Summary of the invention
The purpose of this utility model provides and a kind ofly can overcome above-mentioned insufficient, the safe and reliable miniature digestive tract body fluid sampling device that can swallow of prior art.
The technical scheme that adopts is so for achieving the above object, and promptly a kind of miniature digestive tract liquid sampler comprises capsule shape housing, power supply and controlled in wireless mechanism, and wherein controlled in wireless mechanism includes antenna and signaling conversion circuit; It is characterized in that: be packaged with the movable mechanism of forming by micromachine and sampling storehouse in the housing; Housing is provided with at least one or at least one group of thief hatch; Outer wall in the sampling storehouse has the injection port that at least one or at least one group are communicated with the storehouse of sampling; Driven by motor sampling storehouse is moved vertically or/and rotation makes thief hatch and injection port para-position on the housing realize that sampling or dislocation realize shutoff.
The work process of said apparatus is: after capsule is swallowed digestive tract, after arrival need be carried out the position of liquid sample, antenna receives outside command signal, pass through signaling conversion circuit, be transported to circuit for controlling motor after the conversion, open motor, after drive sampling storehouse is moved specified distance or rotated specified angle, when promptly sampling injection port on the storehouse and the thief hatch para-position on the housing, disable motor; After sampling was finished, capsule received the external control instruction, and starter motor promotes the sampling storehouse and moves specified distance or rotate specified angle, when making injection port on the sampling storehouse with the dislocation of the thief hatch on the housing, promptly finished sampling and sealed thief hatch.
This device has improved the defective of existing digestive tract bodily fluid sampling technology, has the following advantages: (1) encapsulation is simple; (2) before and after the biological fluid extracting, the bodily fluid sampling storehouse is a sealing state, and institute's collection liquid sample can be maintained preferably; (4) sampling mechanism is not subjected to the influence of digestive tract pressure reduction; (5) adopting adsorbing material to sample, is body fluid with what guarantee to be collected substantially; (6) length is controlled the sampling time.(7) independently can sample to the digestive tract diverse location when separately injection port is communicated with in the branch chamber when the sampling storehouse is separated into several, individual packages is not gone here and there sample, can obtain more information.
Description of drawings
The embodiment of the indefiniteness that this utility model can provide by accompanying drawing further specifies.
Structure cutaway view before the sampling of Fig. 1 this utility model embodiment;
Structure cutaway view when Fig. 2 this utility model embodiment samples;
Structure cutaway view after Fig. 3 this utility model embodiment samples and finishes;
The structure that Fig. 4 this utility model embodiment samples after finishing is partly cutd open sketch map.
Among the figure: 1-shell, 2-antenna and control circuit, 3-movable mechanism, the 4-storehouse of sampling, 5-sealing ring, 6-fixed mechanism, 7-micromachine, 8-thief hatch, 9-power transmission shaft, 10-cavity, 11-injection port.
The specific embodiment
This utility model comprises capsule shape housing 1, power supply and controlled in wireless mechanism, and wherein controlled in wireless mechanism comprises antenna and signaling conversion circuit 2; It is characterized in that: be packaged with the movable mechanism of forming by micromachine 7 and sampling storehouse 4 in the housing; Housing 1 is provided with at least one or at least one group of thief hatch 8; Outer wall in the sampling storehouse has the injection port 11 that at least one or at least one group are communicated with the storehouse of sampling; Minitype motor driving sampling storehouse is moved vertically or/and rotation makes thief hatch and the injection port para-position on the sampling storehouse on the housing realize sampling or dislocation realization shutoff.
Above-mentioned sampling storehouse 4 is single cavity or multi-cavity body structure, is filled with liquid absorption material at intracavity.Described liquid absorption material is aseptic sponge, medical cotton or other aseptic fiber.
The same circumference of some thief hatch 8 on housing equidistantly arranged and constituted one group.
Some injection ports corresponding with thief hatch are equidistantly arranged one group of injection port of formation at the same circumference of outer wall in sampling storehouse, and the sampling storehouse is the multi-cavity body structure, and each divides storehouse to be communicated with at least one injection port; Minitype motor driving sampling storehouse rotation makes thief hatch and injection port para-position realize that sampling or dislocation realize shutoff.
For example: the same circumference on housing is 180 ° (or 90 °) and arranges two thief hatch 8, the same circumference of outer wall in the sampling storehouse is 90 ° and equidistantly arranges four injection ports 11, the sampling storehouse is two cavity body structures, and each divides the storehouse to be communicated with at a distance of 180 ° of (or 90 °) injection ports with a pair of; During original state, two pairs of holes misplace 45 °, be in sealed condition, when minitype motor driving sampling storehouse is rotated counterclockwise 45 °, thief hatch para-position on a pair of injection port and the housing is connected, shutoff after rotating 45 ° is rotated 45 ° again and is made another realize another time sampling to injection port and thief hatch and para-position, rotates 45 ° of dislocation again and realizes shutoff.
On the different circumference of sampling storehouse outer wall injection port or injection port group are set, the sampling storehouse is the multi-cavity body structure, and each divides the storehouse to be communicated with injection port or injection port group; Minitype motor driving sampling storehouse moves axially, and makes thief hatch or thief hatch group on the different circumference realize that with the injection port para-position sampling or dislocation realize shutoff respectively.
For example, arrange one group of thief hatch 8 on same circumference on the housing, arrange two groups of injection ports 11 on the twice circumference of the outer wall in sampling storehouse, the sampling storehouse is two cavity body structures, and each Fen Cang is communicated with one group of injection port; During original state, injection port and thief hatch dislocation, be in sealed condition, when minitype motor driving sampling storehouse moves axially, thief hatch para-position on first group of injection port and the housing is connected, first group of injection port shutoff when moving axially again, another is organized injection port and connects with the thief hatch para-position on the housing.Moving axially then again, dislocation realizes shutoff.
Micromachine in the movable mechanism of the present utility model can be positioned at an end in sampling storehouse, and the output shaft of micromachine rotates by the gear driven sampling storehouse that is connected with sampling.
Described sampling storehouse 4 is the circular cylindrical cavity that has of axial tool centre bore, and micromachine is arranged in described centre bore, and the output shaft of micromachine reaches the gear pair drive sampling storehouse that is connected with the sampling storehouse by gear and rotates.
Referring to accompanying drawing, described sampling storehouse 4 is the cavity that half capsule shape is arranged of axial tool centre bore, and micromachine is arranged in described centre bore, the thread bush that the screw engages that the output shaft of micromachine connects by key is connected with the sampling storehouse, drive the sampling storehouse and move axially, enter the cavity 10 of right-hand member.
On the above-mentioned sampling storehouse 4 sealing ring 5 is installed, described sealing ring is embedded on the sampling storehouse housing of both sides of injection port or injection port group.
In the embodiment that accompanying drawing provides, shell 1 is formed by connecting by two sections, and smooth surface offers one group of thief hatch 8 at the correct position of intermediate cylindrical body portion, and each thief hatch is a strip shape gob, equidistantly is arranged on the circumference.Outer wall in the sampling storehouse is provided with one group of injection port corresponding to shell, and each thief hatch is a strip shape gob, equidistantly is arranged on the circumference.
Present embodiment is powered by the power supply that is encapsulated in the shell 1, and this power supply is a button battery, controls the running of micromachine simultaneously by control device of wireless, finishes sampling or approved sample.
In the embodiment that accompanying drawing provides, after the capsule shape sampling apparatus is swallowed digestive tract, after arrival need be carried out the position of liquid sample, antenna receives outside command signal, pass through signaling conversion circuit, be transported to circuit for controlling motor after the conversion, open motor, move the sampling storehouse, after the sampling storehouse arrives assigned address by the rotation of motor shaft, disable motor, after sampling is finished, send the external control instruction, starter motor, rotation by motor shaft promotes the continuation reach of sampling storehouse, until closing sampling.Perhaps be, after capsule is finished sampling, receive the outside and close the sampling instruction that at this moment, control circuit produces a reverse current to motor, the motor reverse rotation makes removable sampling storehouse get back to original state, closes sampling.
Claims (9)
1. a miniature digestive tract liquid sampler comprises capsule shape housing (1), power supply and controlled in wireless mechanism, and wherein controlled in wireless mechanism comprises antenna and signaling conversion circuit (2); It is characterized in that: be packaged with the movable mechanism of forming by micromachine (7) and sampling storehouse (4) in the housing; Housing (1) is provided with at least one or at least one group of thief hatch (8); Outer wall in the sampling storehouse has the injection port (11) that at least one or at least one group are communicated with the storehouse of sampling; Minitype motor driving sampling storehouse is moved vertically or/and rotation makes thief hatch and the injection port para-position on the sampling storehouse on the housing realize sampling or dislocation realization shutoff.
2. miniature digestive tract liquid sampler according to claim 1 is characterized in that: sampling storehouse (4) is single cavity or multi-cavity body structure, is filled with liquid absorption material at intracavity.
3. miniature digestive tract liquid sampler according to claim 1 is characterized in that: the same circumference of some thief hatch (8) on housing equidistantly arranged and constituted one group of thief hatch.
4. miniature digestive tract liquid sampler according to claim 1, it is characterized in that: some injection ports corresponding with thief hatch are equidistantly arranged at the same circumference of outer wall in sampling storehouse and are constituted one group of injection port, the sampling storehouse is the multi-cavity body structure, and each divides the storehouse to be communicated with at least one injection port; Minitype motor driving sampling storehouse rotation makes thief hatch and injection port para-position realize that sampling or dislocation realize shutoff.
5. miniature digestive tract liquid sampler according to claim 1 is characterized in that: on the different circumference of sampling storehouse outer wall injection port or injection port group are set, the sampling storehouse is the multi-cavity body structure, and each divides the storehouse to be communicated with injection port or injection port group; Minitype motor driving sampling storehouse moves axially, and makes thief hatch or thief hatch group on the different circumference realize that with the injection port para-position sampling or dislocation realize shutoff respectively.
6. according to claim 1,2 or 4 described miniature digestive tract liquid samplers, it is characterized in that: micromachine is positioned at an end in sampling storehouse, and the output shaft of micromachine rotates by the gear driven sampling storehouse that is connected with sampling.
7. according to claim 1,2 or 4 described miniature digestive tract liquid samplers, it is characterized in that: described sampling storehouse (4) is for axially having the circular cylindrical cavity of centre bore, micromachine is arranged in described centre bore, and the output shaft of micromachine reaches the gear pair that is connected with the sampling storehouse by gear and drives the rotation of sampling storehouse.
8. according to claim 1,2 or 5 described miniature digestive tract liquid samplers, it is characterized in that: described sampling storehouse (4) is the cavity that half capsule shape is arranged of axial tool centre bore, micromachine is arranged in described centre bore, the output shaft of micromachine drives the sampling storehouse and moves axially by key screw engages that connects and the thread bush that the sampling storehouse is connected.
9. according to claim 1,2,4 or 5 described miniature digestive tract liquid samplers, it is characterized in that: in sampling storehouse (4) sealing ring (5) is installed, described sealing ring is embedded on the sampling storehouse housing of both sides of injection port or injection port group.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202187999U CN201719266U (en) | 2010-06-08 | 2010-06-08 | Mini device for sampling liquid of alimentary canal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010202187999U CN201719266U (en) | 2010-06-08 | 2010-06-08 | Mini device for sampling liquid of alimentary canal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201719266U true CN201719266U (en) | 2011-01-26 |
Family
ID=43487529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010202187999U Expired - Lifetime CN201719266U (en) | 2010-06-08 | 2010-06-08 | Mini device for sampling liquid of alimentary canal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201719266U (en) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970045A (en) * | 2017-12-04 | 2018-05-01 | 山西农业大学 | Intestinal contents negative pressure Autosampler |
| CN108245200A (en) * | 2018-01-10 | 2018-07-06 | 新乡医学院第三附属医院 | A kind of tumor in digestive tract cellular collector |
| CN108670176A (en) * | 2018-06-07 | 2018-10-19 | 庞秀 | A kind of GI Medicine sight glass robot |
| CN109009247A (en) * | 2018-10-19 | 2018-12-18 | 安翰光电技术（武汉）有限公司 | sampling capsule and sampling capsule system |
| CN109009246A (en) * | 2018-10-19 | 2018-12-18 | 安翰光电技术（武汉）有限公司 | sampling capsule and sampling capsule system |
| CN109222874A (en) * | 2018-11-09 | 2019-01-18 | 安翰光电技术（武汉）有限公司 | Alimentary canal sampling capsule |
| CN109497917A (en) * | 2019-01-11 | 2019-03-22 | 安翰科技(武汉)股份有限公司 | Alimentary canal sampling capsule |
| WO2019136081A1 (en) * | 2018-01-02 | 2019-07-11 | The Regents Of The University Of Michigan | Sampling device for drug development and diagnosis of gastric-intestinal diseases |
| CN110037746A (en) * | 2018-01-16 | 2019-07-23 | 上海安翰医疗技术有限公司 | The capsule type digestive tract liquid taking device and its capsule ontology of external magnetic field control |
| CN111035413A (en) * | 2019-12-17 | 2020-04-21 | 华中科技大学鄂州工业技术研究院 | Digestive tract sampling capsule and sampling system |
| WO2020102997A1 (en) * | 2018-11-20 | 2020-05-28 | 深圳华大智造科技有限公司 | Sampling device and digestive tract sampling capsule |
| CN111419292A (en) * | 2020-04-30 | 2020-07-17 | 安翰科技(武汉)股份有限公司 | Sampling/drug delivery capsule |
| CN113331872A (en) * | 2021-05-25 | 2021-09-03 | 上海交通大学 | Miniature suction type alimentary canal multi-position liquid biopsy sampling device |
-
2010
- 2010-06-08 CN CN2010202187999U patent/CN201719266U/en not_active Expired - Lifetime
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970045A (en) * | 2017-12-04 | 2018-05-01 | 山西农业大学 | Intestinal contents negative pressure Autosampler |
| US11647959B2 (en) | 2018-01-02 | 2023-05-16 | The Regents Of The University Of Michigan | Sampling device for drug development and diagnosis of gastric-intestinal diseases |
| WO2019136081A1 (en) * | 2018-01-02 | 2019-07-11 | The Regents Of The University Of Michigan | Sampling device for drug development and diagnosis of gastric-intestinal diseases |
| CN108245200A (en) * | 2018-01-10 | 2018-07-06 | 新乡医学院第三附属医院 | A kind of tumor in digestive tract cellular collector |
| CN110037746A (en) * | 2018-01-16 | 2019-07-23 | 上海安翰医疗技术有限公司 | The capsule type digestive tract liquid taking device and its capsule ontology of external magnetic field control |
| CN110037746B (en) * | 2018-01-16 | 2024-01-09 | 上海安翰医疗技术有限公司 | External magnetic field controlled capsule type alimentary canal liquid taking device and capsule body thereof |
| CN108670176A (en) * | 2018-06-07 | 2018-10-19 | 庞秀 | A kind of GI Medicine sight glass robot |
| CN108670176B (en) * | 2018-06-07 | 2020-06-30 | 庞秀 | Gastroenterology speculum robot |
| CN109009247A (en) * | 2018-10-19 | 2018-12-18 | 安翰光电技术（武汉）有限公司 | sampling capsule and sampling capsule system |
| CN109009246A (en) * | 2018-10-19 | 2018-12-18 | 安翰光电技术（武汉）有限公司 | sampling capsule and sampling capsule system |
| CN109009246B (en) * | 2018-10-19 | 2023-11-28 | 安翰科技(武汉)股份有限公司 | Sampling capsules and sampling capsule systems |
| CN109009247B (en) * | 2018-10-19 | 2023-09-08 | 安翰科技(武汉)股份有限公司 | Sampling capsule and sampling capsule system |
| CN109222874B (en) * | 2018-11-09 | 2024-04-09 | 安翰科技(武汉)股份有限公司 | Digestive tract sampling capsule |
| CN109222874A (en) * | 2018-11-09 | 2019-01-18 | 安翰光电技术（武汉）有限公司 | Alimentary canal sampling capsule |
| WO2020102997A1 (en) * | 2018-11-20 | 2020-05-28 | 深圳华大智造科技有限公司 | Sampling device and digestive tract sampling capsule |
| CN113194807A (en) * | 2018-11-20 | 2021-07-30 | 深圳华大智造科技股份有限公司 | Sampling device and digestive tract sampling capsule |
| CN113194807B (en) * | 2018-11-20 | 2023-09-26 | 深圳华大智造科技股份有限公司 | Sampling device and alimentary canal sampling capsule |
| CN109497917A (en) * | 2019-01-11 | 2019-03-22 | 安翰科技(武汉)股份有限公司 | Alimentary canal sampling capsule |
| CN111035413A (en) * | 2019-12-17 | 2020-04-21 | 华中科技大学鄂州工业技术研究院 | Digestive tract sampling capsule and sampling system |
| WO2021218971A1 (en) * | 2020-04-30 | 2021-11-04 | 安翰科技(武汉)股份有限公司 | Sampling/administration capsule |
| CN111419292A (en) * | 2020-04-30 | 2020-07-17 | 安翰科技(武汉)股份有限公司 | Sampling/drug delivery capsule |
| CN113331872B (en) * | 2021-05-25 | 2023-03-14 | 上海交通大学 | Miniature suction type alimentary canal multi-position liquid biopsy sampling device |
| CN113331872A (en) * | 2021-05-25 | 2021-09-03 | 上海交通大学 | Miniature suction type alimentary canal multi-position liquid biopsy sampling device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: Mini device for sampling liquid of alimentary canal Effective date of registration: 20160421 Granted publication date: 20110126 Pledgee: Chongqing Three Gorges bank Limited by Share Ltd Jiangbei Branch Pledgor: Chongqing Jinshan Science and Technology Inc. Registration number: 2016500000005 |
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| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20171106 Granted publication date: 20110126 Pledgee: Chongqing Three Gorges bank Limited by Share Ltd Jiangbei Branch Pledgor: Chongqing Jinshan Science and Technology Inc. Registration number: 2016500000005 |
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| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| CX01 | Expiry of patent term |
Granted publication date: 20110126 |
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| CX01 | Expiry of patent term |