CN204813798U - Hand -held type fundus camera based on liquid lens - Google Patents
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Abstract
Description
技术领域technical field
本实用新型涉及医学影像领域,尤其涉及一种基于液体透镜的手持式眼底照相机。The utility model relates to the field of medical imaging, in particular to a hand-held fundus camera based on a liquid lens.
背景技术Background technique
手持式眼底照相机属于医学影像领域,用于获取人眼视网膜图像,起到眼底病检查以及辅助其他器官病情判断的功能。目前手持式眼底照相机的调焦主要有两种方法,一种是调节光学组件或者是传感器相对位置的手动调焦方式,另一种是自动调焦方式。而当前的手动调焦和自动调焦方式都需要复杂的机械和电机驱动方式,限制了手持式眼底照相机体积、重量和电池续航时间等指标的提升。The hand-held fundus camera belongs to the field of medical imaging, and is used to obtain images of the retina of the human eye, to perform fundus disease inspection and to assist in the judgment of other organs. At present, there are mainly two methods for focusing the handheld fundus camera, one is manual focusing by adjusting the relative position of optical components or sensors, and the other is automatic focusing. However, the current manual focusing and automatic focusing methods require complex mechanical and motor drive methods, which limit the improvement of hand-held fundus cameras in terms of size, weight and battery life.
随着能动光学器件的发展,能动光学技术逐步应用到眼科光学成像中,如激光共聚焦技术。在眼底照相机领域,有的眼底照相机采用变形镜消除眼睛和成像光学系统像差实现细胞级成像,这种眼底照相机使用激光或者闪光灯作为照明光源,而由于其采用了MEMS或者压电陶瓷驱动的变形镜,系统需要高压放大器驱动变形镜,另外这类眼底显微镜光路非常复杂,不能满足手持式设备对便携性、灵活性的要求。With the development of active optical devices, active optical technology is gradually applied to ophthalmic optical imaging, such as laser confocal technology. In the field of fundus cameras, some fundus cameras use deformable mirrors to eliminate the aberrations of the eyes and imaging optical systems to achieve cell-level imaging. The system requires a high-voltage amplifier to drive the deformable mirror. In addition, the optical path of this type of fundus microscope is very complicated, which cannot meet the portability and flexibility requirements of handheld devices.
液体透镜是近年来发展起来廉价的能动光学器件,它采用液体作为光通道,利用电磁驱动技术改变液体透镜的光焦度,达到调焦的目的。由于液体透镜无需额外机械调焦机构,降低了光学系统的体积,已经在内窥镜中取得了应用。其中,申请号为201310728493.6的中国发明专利公开了一种基于变曲率式液体透镜的便携式眼底照相机,主要目的是采用液体变曲率透镜代替传统的机械调焦结构,起到简化系统结构的目的。该发明采用分光镜合束的方式实现引导光和白光的眼底照明,在成像光路中又引入了一个分光镜、十字叉丝和目标定位器实现视轴和光轴的重合,其对焦方式是手动调节液体凸透镜的控制参数,没有实现自动对焦。但是,由于该发明的技术路线引入了两个分光镜、十字叉丝和目标定位器等光学元件,使得光路较为复杂,增加了相机的装调难度,而且眼底反射回光非常弱,故分光镜的引入进一步增加了对传感器和曝光量的要求,使系统成本难以降低,人眼所承担的光辐射量也较大。Liquid lens is an inexpensive active optical device developed in recent years. It uses liquid as the optical channel and uses electromagnetic drive technology to change the optical power of the liquid lens to achieve the purpose of focusing. Since the liquid lens does not require an additional mechanical focusing mechanism and reduces the volume of the optical system, it has been applied in the endoscope. Among them, the Chinese invention patent with application number 201310728493.6 discloses a portable fundus camera based on a variable curvature liquid lens. The main purpose is to replace the traditional mechanical focusing structure with a liquid variable curvature lens to simplify the system structure. The invention adopts beam splitting to achieve the fundus illumination of guided light and white light, and introduces a beam splitter, crosshair and target locator in the imaging optical path to achieve the coincidence of visual axis and optical axis. The focusing method is manual adjustment. The control parameters of the liquid convex lens do not achieve autofocus. However, because the technical route of this invention introduces optical components such as two beam splitters, crosshairs and target locators, the optical path is more complicated, which increases the difficulty of camera installation and adjustment, and the reflected light from the fundus is very weak, so the beam splitter The introduction of the sensor further increases the requirements for the sensor and exposure, making it difficult to reduce the system cost, and the amount of light radiation borne by the human eye is also relatively large.
实用新型内容Utility model content
针对现有技术的不足,本实用新型旨在提供一种结构简单、体积小,且能实现全自动对焦的基于液体透镜的手持式眼底照相机。Aiming at the deficiencies of the prior art, the utility model aims to provide a hand-held fundus camera based on a liquid lens, which has a simple structure, a small volume, and can realize automatic focusing.
为实现上述目的,本实用新型采用如下技术方案:In order to achieve the above object, the utility model adopts the following technical solutions:
一种基于液体透镜的手持式眼底照相机,包括壳体,所述壳体内部设有照明光源、图像传感器、第一透镜组件、第二透镜组件、液体透镜、驱动电路、信号处理单元、控制组件以及电源组件;A hand-held fundus camera based on a liquid lens, comprising a casing, the casing is internally provided with an illumination light source, an image sensor, a first lens assembly, a second lens assembly, a liquid lens, a driving circuit, a signal processing unit, and a control assembly and power components;
所述照明光源,用于对眼底进行照明;The illumination light source is used for illuminating the fundus;
所述图像传感器,用于将获取的图像的光学信号转换为数字信号;The image sensor is used to convert the optical signal of the acquired image into a digital signal;
所述第一透镜组件,位于所述壳体的左前端,用于将所述照明光源发出的光束聚焦到眼底,形成对眼底的均匀照明,还用于聚拢眼底反射回来的光束;The first lens assembly, located at the left front end of the housing, is used to focus the light beam emitted by the illumination source onto the fundus to form uniform illumination on the fundus, and is also used to gather the beam reflected back by the fundus;
所述第二透镜组件,位于所述第一透镜组件与图像传感器之间,用于与第一透镜组件一起将眼底反射回来的光束聚焦到图像传感器上;The second lens assembly is located between the first lens assembly and the image sensor, and is used to focus the light beam reflected from the fundus onto the image sensor together with the first lens assembly;
所述信号处理单元,用于控制照明光源的工作状态,还用于接收处理图像传感器采集到的数字信号,以获取图像的清晰度评价指标,并根据图像的清晰度评价指标发出一控制信号来控制驱动电路的工作状态;The signal processing unit is used to control the working state of the lighting source, and is also used to receive and process the digital signal collected by the image sensor to obtain the image definition evaluation index, and send a control signal according to the image definition evaluation index to Control the working state of the drive circuit;
所述驱动电路,用于接收所述信号处理单元发出的控制信号以驱动液体透镜的工作状态;The driving circuit is used to receive the control signal sent by the signal processing unit to drive the working state of the liquid lens;
所述控制组件,用于与信号处理单元相连,以实现拍照控制;The control component is used to connect with the signal processing unit to realize the photographing control;
所述电源组件,用于为照明光源、图像传感器、驱动电路、信号处理单元以及控制组件供电;The power supply component is used to supply power to the lighting source, the image sensor, the drive circuit, the signal processing unit and the control component;
其中所述液体透镜位于第一透镜组件和第二透镜组件之间,或者第二透镜组件和图像传感器之间。Wherein the liquid lens is located between the first lens assembly and the second lens assembly, or between the second lens assembly and the image sensor.
优选的,所述照明光源包括至少一个引导光源以及至少一个曝光光源,所述引导光源与曝光光源均与信号处理单元相连。Preferably, the illumination light source includes at least one guiding light source and at least one exposure light source, and both the guiding light source and the exposure light source are connected to the signal processing unit.
优选的,所述第一透镜组件为一个非球面透镜。Preferably, the first lens component is an aspherical lens.
优选的,所述第二透镜组件由两个分离的双胶合透镜构成。Preferably, said second lens assembly consists of two separate doublet lenses.
优选的,所述控制组件为与信号处理单元相连的机械按键或触控屏中的任一种。Preferably, the control component is any one of a mechanical button or a touch screen connected to the signal processing unit.
优选的,所述手持式眼底照相机还包括显示模块、数据存储单元以及数据传输接口;所述显示模块、数据存储单元以及数据传输接口均与信号处理单元相连,并均由电源组件供电。Preferably, the handheld fundus camera further includes a display module, a data storage unit and a data transmission interface; the display module, the data storage unit and the data transmission interface are all connected to the signal processing unit and powered by a power supply component.
优选的,所述显示模块位于所述壳体的外侧,所述数据存储单元以及数据传输接口均装嵌于所述壳体的内部。Preferably, the display module is located outside the housing, and the data storage unit and the data transmission interface are embedded in the housing.
优选的,所述数据传输接口为有线数据接口和无线数据接口中的一种。Preferably, the data transmission interface is one of a wired data interface and a wireless data interface.
本实用新型的有益效果如下:The beneficial effects of the utility model are as follows:
该基于液体透镜的手持式眼底照相机的结构简单、体积小,能够基于图像清晰度指标的反馈控制实现全自动对焦。本实用新型中的光路较为简单,减少了相机的装调难度,使得人眼所承担的光辐射量较小,而眼底反射回来的光束较强。并且在保证拍摄质量的同时也使得基于液体透镜的手持式眼底照相机的生产成本降低。The liquid lens-based hand-held fundus camera has a simple structure and a small volume, and can realize automatic focusing based on the feedback control of the image definition index. The optical path in the utility model is relatively simple, which reduces the difficulty of camera installation and adjustment, so that the amount of light radiation borne by the human eye is relatively small, and the light beam reflected back by the fundus is relatively strong. And while ensuring the shooting quality, it also reduces the production cost of the hand-held fundus camera based on the liquid lens.
附图说明Description of drawings
图1为本实用新型基于液体透镜的手持式眼底照相机的较佳实施方式的结构图。FIG. 1 is a structural diagram of a preferred embodiment of the liquid lens-based handheld fundus camera of the present invention.
图2为本实用新型基于液体透镜的手持式眼底照相机的较佳实施方式的照明光路。Fig. 2 is the illumination light path of a preferred embodiment of the liquid lens-based hand-held fundus camera of the present invention.
图3为本实用新型基于液体透镜的手持式眼底照相机的较佳实施方式的成像光路。Fig. 3 is the imaging optical path of a preferred embodiment of the liquid lens-based handheld fundus camera of the present invention.
具体实施方式Detailed ways
下面将结合附图以及具体实施方式,对本实用新型做进一步描述:Below in conjunction with accompanying drawing and specific embodiment, the utility model is further described:
请参见图1,本实用新型涉及一种基于液体透镜的手持式眼底照相机,其较佳实施方式包括壳体12,壳体12内部设有照明光源1、图像传感器2、第一透镜组件3、第二透镜组件4、液体透镜10、驱动电路11、信号处理单元5、控制组件6以及电源组件13。Please refer to Fig. 1, the utility model relates to a hand-held fundus camera based on a liquid lens, and its preferred embodiment includes a housing 12, the housing 12 is internally provided with an illumination source 1, an image sensor 2, a first lens assembly 3, The second lens assembly 4 , the liquid lens 10 , the drive circuit 11 , the signal processing unit 5 , the control assembly 6 and the power supply assembly 13 .
具体的,照明光源1,用于对眼底进行照明。这里的照明光源为能够发出波长在400nm-2000nm之间的窄波段单色或宽波段光束的光源。照明光源可以是发光二极管、激光器和闪光灯中的一种,也可以是多个以上光源的组合。作为优选的,照明光源1包括至少一个引导光源以及至少一个曝光光源,而引导光源与曝光光源均与信号处理单元相连。引导光源可以在信号处理单元的控制下进行关闭和打开。曝光光源可以在信号处理单元的控制下进行曝光,其中曝光时间一般在0.2毫秒-300毫秒之间。进一步优选的,照明光源1可以包括一个红外LED(850nm波段)和一个白光LED(450nm-650nm),红外LED和白光LED均可以镶嵌在同一个PCB板上,其中红外LED可以用作引导光源,白光LED可以用作曝光光源。Specifically, the illumination light source 1 is used for illuminating the fundus. Here, the illumination light source is a light source capable of emitting monochromatic or wide-band light beams with a wavelength between 400nm and 2000nm. The illumination light source can be one of light emitting diodes, lasers and flash lamps, or a combination of more than one of the above light sources. Preferably, the illumination light source 1 includes at least one guiding light source and at least one exposure light source, and both the guiding light source and the exposure light source are connected to the signal processing unit. The guiding light source can be turned off and on under the control of the signal processing unit. The exposure light source can be exposed under the control of the signal processing unit, wherein the exposure time is generally between 0.2 milliseconds and 300 milliseconds. Further preferably, the illuminating light source 1 may include an infrared LED (850nm band) and a white LED (450nm-650nm), both the infrared LED and the white LED may be embedded on the same PCB, wherein the infrared LED may be used as a guiding light source, White LEDs can be used as the exposure light source.
图像传感器2,用于将获取的图像的光学信号转换为数字信号。这里的图像传感器是一个二维图像传感器,其可以是CCD、CMOS或由一维传感阵列组成的二维光电传感器件中的一种。作为优选的,图像传感器可以是一个1920*1080分辨率的CMOS芯片。The image sensor 2 is used to convert the optical signal of the acquired image into a digital signal. The image sensor here is a two-dimensional image sensor, which may be one of CCD, CMOS or two-dimensional photoelectric sensing devices composed of one-dimensional sensing arrays. Preferably, the image sensor may be a CMOS chip with a resolution of 1920*1080.
如图2和图3所示,第一透镜组件3,位于所述壳体的左前端,用于将所述照明光源发出的光束聚焦到眼底,形成对眼底的均匀照明,即形成照明光路。第一透镜组件还用于聚拢眼底反射回来的光束,用于形成成像光路。其中,该第一透镜组件由一组光学元件或者空间距离构成,作为优选的,其具体可以是一个非球面透镜。As shown in Fig. 2 and Fig. 3, the first lens assembly 3 is located at the left front end of the housing, and is used to focus the light beam emitted by the illumination source onto the fundus to form uniform illumination on the fundus, that is, to form an illumination optical path. The first lens assembly is also used to gather the light beams reflected by the fundus to form an imaging optical path. Wherein, the first lens assembly is composed of a group of optical elements or spatial distances, and preferably, it may specifically be an aspherical lens.
第二透镜组件4,位于第一透镜组件3与图像传感器2之间,用于与第一透镜组件3一起将眼底反射回来的光束聚焦到图像传感器2上。这里的第二透镜组件由一组光学元件或者空间距离构成,每组光学元件包含至少一个透镜。其中,作为优选的,第二透镜组件可以由两个分离的双胶合透镜构成。这里的双胶合透镜还起到了校正色差的作用。The second lens assembly 4 , located between the first lens assembly 3 and the image sensor 2 , is used to focus the light beam reflected back from the fundus onto the image sensor 2 together with the first lens assembly 3 . The second lens assembly here is composed of a set of optical elements or spatial distances, each set of optical elements includes at least one lens. Wherein, preferably, the second lens assembly may be composed of two separated doublet lenses. The doublet lens here also plays a role in correcting chromatic aberration.
信号处理单元5,用于控制照明光源的工作状态,还用于接收处理图像传感器采集到的数字信号,以获取图像的清晰度评价指标,并根据图像的清晰度评价指标发出一控制信号来控制驱动电路11的工作状态。这里的信号处理单元5可以是一个包含DSP和ARM芯片的SOC。该控制信号能够控制驱动电路11加载到液体透镜10的信号强度。为得到上述控制信号,信号处理单元包括一液体透镜控制算法模块,液体透镜控制算法模块根据图像清晰度评价指标计算加载以得到液体透镜控制器的信号强度,即作用于驱动电路的控制信号。The signal processing unit 5 is used to control the working state of the lighting source, and is also used to receive and process the digital signal collected by the image sensor to obtain the image definition evaluation index, and send a control signal according to the image definition evaluation index to control The working state of the drive circuit 11. The signal processing unit 5 here may be a SOC including DSP and ARM chips. The control signal can control the strength of the signal loaded by the drive circuit 11 to the liquid lens 10 . In order to obtain the above control signal, the signal processing unit includes a liquid lens control algorithm module. The liquid lens control algorithm module calculates and loads according to the image definition evaluation index to obtain the signal strength of the liquid lens controller, that is, the control signal acting on the drive circuit.
其中,图像清晰度评价指标是眼底图像灰度值的变换,一般选取一个区域或图像数个区域内灰度值的和,或者是平方和,或者是几次方和,也可以是基于灰度值梯度、图像熵、基于频域傅里叶变换或者是小波变换的值。Among them, the image clarity evaluation index is the transformation of the gray value of the fundus image. Generally, the sum of gray values in an area or several areas of the image is selected, or the sum of squares, or the sum of several times, or based on gray Value gradient, image entropy, value based on frequency-domain Fourier transform or wavelet transform.
液体透镜控制算法模块采用的是基于图像清晰度评价指标的反馈控制算法,可以是PID、遗传算法、随机并行梯度下降算法、模拟退火算法或者查表法。作为优选的,液体透镜控制算法模块采用爬山法,爬山法是一种随机反馈控制算法。因为图像清晰度评价指标和液体透镜的控制信号之间很难得到一个解析表达式,这类情况下一般采用随机反馈控制算法实现图像清晰度指标的最大化,从而使获得图片清晰度最高。The liquid lens control algorithm module adopts a feedback control algorithm based on image definition evaluation index, which can be PID, genetic algorithm, stochastic parallel gradient descent algorithm, simulated annealing algorithm or look-up table method. Preferably, the liquid lens control algorithm module adopts a hill-climbing method, which is a random feedback control algorithm. Because it is difficult to obtain an analytical expression between the image definition evaluation index and the control signal of the liquid lens, in this case, the random feedback control algorithm is generally used to maximize the image definition index, so that the highest image definition can be obtained.
驱动电路11,用于接收所述信号处理单元发出的控制信号以驱动液体透镜10的工作状态。其中,驱动电路通过I2C接口与信号处理单元连接,用于接收信号处理单元的控制信号,并将该控制信号转换后加载到液体透镜上,以完成对液体透镜焦距的控制。其中液体透镜10位于第一透镜组件和第二透镜组件之间,或者第二透镜组件和图像传感器之间。The driving circuit 11 is used to receive the control signal sent by the signal processing unit to drive the working state of the liquid lens 10 . Wherein, the drive circuit is connected with the signal processing unit through the I2C interface, and is used to receive the control signal of the signal processing unit, and load the control signal to the liquid lens after conversion, so as to complete the control of the focal length of the liquid lens. The liquid lens 10 is located between the first lens assembly and the second lens assembly, or between the second lens assembly and the image sensor.
控制组件6,用于与信号处理单元5相连,以实现拍照控制。控制组件作为一个输入装置,可以为与信号处理单元相连的机械按键或触控屏中的任一种。The control component 6 is used to connect with the signal processing unit 5 to realize the photographing control. As an input device, the control component can be any one of a mechanical button or a touch screen connected to the signal processing unit.
再者,电源组件13,用于为照明光源、图像传感器、驱动电路、信号处理单元以及控制组件供电。电源组件可以是锂电池,当然也可以是其他类型的电池。Furthermore, the power supply component 13 is used for supplying power to the illumination light source, the image sensor, the driving circuit, the signal processing unit and the control component. The power supply component can be a lithium battery, and of course can also be other types of batteries.
作为进一步优选的,手持式眼底照相机还包括显示模块7、数据存储单元8以及数据传输接口9;所述显示模块7、数据存储单元8以及数据传输接口9均与信号处理单元相连,并均由电源组件供电。显示模块位于所述壳体的外侧,数据存储单元以及数据传输接口均装嵌于所述壳体的内部。As further preferably, the hand-held fundus camera also includes a display module 7, a data storage unit 8 and a data transmission interface 9; the display module 7, the data storage unit 8 and the data transmission interface 9 are all connected to the signal processing unit, and are controlled by The power pack supplies power. The display module is located outside the casing, and the data storage unit and the data transmission interface are embedded in the casing.
其中,控制组件6能够通过信号处理单元5控制显示模块7的工作状态,即实现图片的浏览。数据存储单元8可以是机械硬盘,也可以是固态硬盘,也可以是SD或T-Flash等存储卡。数据传输接口9为有线数据接口和无线数据接口中的一种。当数据传输接口9为有线数据接口时,其可以是USB接口,也可以是CameraLink接口。当数据传输接口9为无线数据接口时,其可以是Wifi接口、Zigbee接口以及蓝牙接口中的任一种。Wherein, the control component 6 can control the working state of the display module 7 through the signal processing unit 5, that is, to realize browsing of pictures. The data storage unit 8 can be a mechanical hard disk, a solid state disk, or a memory card such as SD or T-Flash. The data transmission interface 9 is one of a wired data interface and a wireless data interface. When the data transmission interface 9 is a wired data interface, it may be a USB interface or a CameraLink interface. When the data transmission interface 9 is a wireless data interface, it can be any one of a Wifi interface, a Zigbee interface and a Bluetooth interface.
具体的,本实用新型的基于液体透镜的手持式眼底照相机的照明光路和成像光路分别如图2和图3所示。照明光源发出的光通过第一透镜组件进入人眼以形成照明光路。同时眼底反射回来的光束依次通过第一透镜组件、第二透镜组件以及液体透镜聚焦到图像传感器上,图形传感器将获取的图像的光学信号转换为数字信号并传送给信号处理单元,以获取图像的清晰度评价指标,并根据图像的清晰度评价指标发出一控制信号,该控制信号用于控制驱动电路以使得液体透镜进行自动调焦,从而获得清晰度更高的图片。Specifically, the illumination optical path and imaging optical path of the hand-held fundus camera based on the liquid lens of the present invention are shown in Fig. 2 and Fig. 3 respectively. The light emitted by the illumination source enters the human eye through the first lens assembly to form an illumination light path. At the same time, the light beam reflected by the fundus is focused on the image sensor through the first lens assembly, the second lens assembly and the liquid lens in sequence, and the image sensor converts the optical signal of the acquired image into a digital signal and sends it to the signal processing unit to obtain the image The definition evaluation index, and send a control signal according to the image definition evaluation index, and the control signal is used to control the driving circuit to make the liquid lens automatically focus, so as to obtain a picture with higher definition.
对于本领域的技术人员来说,可根据以上描述的技术方案以及构思,做出其它各种相应的改变以及变形,而所有的这些改变以及变形都应该属于本实用新型权利要求的保护范围之内。For those skilled in the art, various other corresponding changes and modifications can be made according to the technical solutions and ideas described above, and all these changes and modifications should fall within the protection scope of the claims of the present invention .
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