CN1907374A - Chinese medicinal composition for treating oral disease - Google Patents
Chinese medicinal composition for treating oral disease Download PDFInfo
- Publication number
- CN1907374A CN1907374A CN 200610112041 CN200610112041A CN1907374A CN 1907374 A CN1907374 A CN 1907374A CN 200610112041 CN200610112041 CN 200610112041 CN 200610112041 A CN200610112041 A CN 200610112041A CN 1907374 A CN1907374 A CN 1907374A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- herba houttuyniae
- xylitol
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 25
- 208000025157 Oral disease Diseases 0.000 title claims abstract description 10
- 208000030194 mouth disease Diseases 0.000 title claims abstract description 10
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 29
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 29
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 29
- 239000000811 xylitol Substances 0.000 claims abstract description 29
- 229960002675 xylitol Drugs 0.000 claims abstract description 29
- 235000010447 xylitol Nutrition 0.000 claims abstract description 29
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 claims abstract description 25
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 40
- 239000003814 drug Substances 0.000 claims description 26
- 241000219109 Citrullus Species 0.000 claims description 24
- 239000013078 crystal Substances 0.000 claims description 24
- 241000628997 Flos Species 0.000 claims description 12
- 201000010099 disease Diseases 0.000 claims description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 9
- 235000014443 Pyrus communis Nutrition 0.000 claims description 8
- 238000007796 conventional method Methods 0.000 claims description 8
- 235000013305 food Nutrition 0.000 claims description 8
- 230000036407 pain Effects 0.000 claims description 8
- 208000002399 aphthous stomatitis Diseases 0.000 claims description 7
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 6
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims description 6
- 241000233835 Tradescantia Species 0.000 claims description 6
- 229940112822 chewing gum Drugs 0.000 claims description 6
- 235000015218 chewing gum Nutrition 0.000 claims description 6
- NOOLISFMXDJSKH-UHFFFAOYSA-N p-menthan-3-ol Chemical compound CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 208000002193 Pain Diseases 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 5
- 208000007117 Oral Ulcer Diseases 0.000 claims description 4
- 201000007100 Pharyngitis Diseases 0.000 claims description 4
- 230000001154 acute effect Effects 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 208000003265 stomatitis Diseases 0.000 claims description 4
- 230000008961 swelling Effects 0.000 claims description 4
- 206010018286 Gingival pain Diseases 0.000 claims description 3
- 206010018291 Gingival swelling Diseases 0.000 claims description 3
- 206010042674 Swelling Diseases 0.000 claims description 3
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000000796 flavoring agent Substances 0.000 claims description 3
- 235000019634 flavors Nutrition 0.000 claims description 3
- 210000003026 hypopharynx Anatomy 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 3
- 206010013952 Dysphonia Diseases 0.000 claims description 2
- 208000010473 Hoarseness Diseases 0.000 claims description 2
- -1 Oleum menthae Chemical compound 0.000 claims description 2
- 208000016150 acute pharyngitis Diseases 0.000 claims description 2
- 206010001093 acute tonsillitis Diseases 0.000 claims description 2
- 239000002775 capsule Substances 0.000 claims description 2
- 229940068682 chewable tablet Drugs 0.000 claims description 2
- 239000007910 chewable tablet Substances 0.000 claims description 2
- 239000000084 colloidal system Substances 0.000 claims description 2
- 230000003628 erosive effect Effects 0.000 claims description 2
- 210000002200 mouth mucosa Anatomy 0.000 claims description 2
- 229940023488 pill Drugs 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 230000004083 survival effect Effects 0.000 claims description 2
- 239000006188 syrup Substances 0.000 claims description 2
- 235000020357 syrup Nutrition 0.000 claims description 2
- 208000004371 toothache Diseases 0.000 claims description 2
- 230000000699 topical effect Effects 0.000 claims description 2
- 231100000331 toxic Toxicity 0.000 claims description 2
- 230000002588 toxic effect Effects 0.000 claims description 2
- 238000012797 qualification Methods 0.000 claims 1
- 244000241235 Citrullus lanatus Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 7
- 238000003809 water extraction Methods 0.000 description 5
- QBDCOUHKEVYWLO-UHFFFAOYSA-N Decanoylacetaldehyde Natural products CCCCCCCCCC(=O)CC=O QBDCOUHKEVYWLO-UHFFFAOYSA-N 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 208000002925 dental caries Diseases 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 235000008216 herbs Nutrition 0.000 description 3
- 208000035824 paresthesia Diseases 0.000 description 3
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 3
- 206010007134 Candida infections Diseases 0.000 description 2
- 244000270200 Citrullus vulgaris Species 0.000 description 2
- 244000241257 Cucumis melo Species 0.000 description 2
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 208000007027 Oral Candidiasis Diseases 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 241000287411 Turdidae Species 0.000 description 2
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 2
- 201000003984 candidiasis Diseases 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- RSIJVJUOQBWMIM-UHFFFAOYSA-L sodium sulfate decahydrate Chemical compound O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O RSIJVJUOQBWMIM-UHFFFAOYSA-L 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010044008 tonsillitis Diseases 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- XLYLQUQHYUOPIW-UHFFFAOYSA-N 3-oxo-Tetradecanal Chemical compound CCCCCCCCCCCC(=O)CC=O XLYLQUQHYUOPIW-UHFFFAOYSA-N 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 235000012840 Citrullus vulgaris Nutrition 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000005577 Gastroenteritis Diseases 0.000 description 1
- 206010054787 Haemorrhoidal haemorrhage Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010023379 Ketoacidosis Diseases 0.000 description 1
- 208000007976 Ketosis Diseases 0.000 description 1
- 241000589902 Leptospira Species 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 208000015634 Rectal Neoplasms Diseases 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 241000758742 Saururaceae Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 206010051373 Wound haemorrhage Diseases 0.000 description 1
- 241000607757 Xenorhabdus Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 230000023852 carbohydrate metabolic process Effects 0.000 description 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 239000000890 drug combination Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 208000010932 epithelial neoplasm Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 150000002972 pentoses Chemical class 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 206010038038 rectal cancer Diseases 0.000 description 1
- 201000001275 rectum cancer Diseases 0.000 description 1
- 230000009711 regulatory function Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 210000004894 snout Anatomy 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 210000002229 urogenital system Anatomy 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 230000004127 xylose metabolism Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a medicinal composition for preventing and treating oral diseases, which comprises raw materials of xylitol, cordate houttuynia extract and water melon frost as the basis formulation.
Description
Technical field
The invention belongs to the pharmaceutical technology field, be specifically related to a kind of Chinese medicine composition and in the application that prevents and treats aspect the oral disease, said composition basis prescription is made up of xylitol, Herba Houttuyniae extract and watermelon crystal.
Background technology
Xylitol
Xylitol is a kind of pentose alcohol, is the normal intermediate product of xylose metabolism, and profile is the crystallinity white powder, extensively is present in the plants such as the group food of fruit, vegetable, frumentum, mushroom and timber, Caulis et Folium Oryzae, corn cob.It can be used as the extensive use in industry such as chemical industry, food, medicine of sweeting agent, nutrient and medicament.Four big healthy definition of xylitol: 1. additional heat.The quantity of heat production and the glucose of xylitol are similar, can be used as the nutritional drugs of additional heat clinically.2. improve carbohydrate metabolism.Xylitol metabolism does not in vivo rely on the participation of insulin, directly permeate through cell membranes involved in sugar metabolism and do not increase blood sugar concentration, and its sweet taste and glucose are similar, also can promote insulin to secrete on a small quantity, so can be used for the succedaneum of diabetics as sugar.3. inhibition ketoplasia.Xylitol can make blood plasma fatty acid generate minimizing, the drug combination of ketoacidosis when can be used as diabetes, surgery anesthesia.4. prevent and treat dental caries.Xylitol can suppress to cause the bacteria breed of dental caries growth, thereby reaches good anti-dental caries effect.
Herba Houttuyniae
Herba Houttuyniae is commonly called as hog snout hole, Herba Houttuyniae, is the root or the herb of Saururaceae herbaceos perennial Herba Houttuyniae." integration of edible and medicinal herbs ", China just ate Herba Houttuyniae before more than 2,000 years as the wild herbs assistant.Passing on from one to another the The Spring and Autumn Period gets over the king and colludes to trample and endure hardships to accomplish some ambition, refine in meaning pursues a goal with determination, and once leads everybody to select Herba Houttuyniae and eat it, useless waste to allay one's hunger; Rise during Wei Jin, Herba Houttuyniae is just formally as medicinal, with the medical ancient books and records of name income of " Herba Houttuyniae ".In historical upheaval development, it just plays the part of medicine, the dual-purpose dual role of food always, for common people's health care, preventing and curing diseases bringing into play acts on.More and more uphold nature, pursuit are very plain along with modern people, and in various places (especially China southwest), Herba Houttuyniae wild or tame kind has become " the main road wild herbs " of having a sudden rise in social status on the popular dining table.
Herba Houttuyniae is cooked, and eats the best raw, but its fragrance uniqueness, the other tool of mouthfeel, the agreeable to the taste people of local flavor.Cold and dressed with sauce going with rice or bread makes National People's Congress appetizing mouthful, appetite stimulator, improves digestive function, also have stir-fry and eat, fry in shallow oil soup, cook congee, the different Dietotherapy methods of fricassee.
Herba Houttuyniae is used as medicine, the traditional Chinese medical science is thought its acrid in the mouth, cold, skin ulcer, promoting urination to remove dampness, invigorating the stomach and promoting digestion are treated in energy heat-clearing and toxic substances removing, the detumescence of row's pain, with controlling excess-heat, pyretic toxicity, damp, disease heat is the lung abscess suffered from, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc., list is used or the compatibility compound recipe, the equal determined curative effect of the use of oral administration and externally or multiple Dietotherapy method among the people.Pharmacological research, the Herba Houttuyniae master contains volatile oil, multiple components such as decanoylacetaldehyde houttuynine sodium bisulfite, various Xenorhabduses, coccus, influenza virus, leptospira etc. there is the inhibition antibacterial action, and can improve the human immunity regulatory function, as in the Herba Houttuyniae liquid of 1: 40000 concentration, staphylococcus aureus is still had inhibitory action, so it has significant anti-inflammation usefulness.Dosage forms such as houttuynine sodium bisulfite has now been made sheet, pin, dashed, atomizing are widely used in the control of human body respiration, digestion, infectious diseases of urogenital system.
Have data to show, from Herba Houttuyniae, isolate a kind of cancer-resisting material abroad, except that to gastric cancer effectively, and medium and advanced lung cancer, chorionic epithelioma, malignant mole, rectal cancer also had certain control Accommodation.In Japan, Herba Houttuyniae is favored, be referred to as " ten medicines " traditionally, as the good vegetables of fashionable health care, think that Herba Houttuyniae has obviously effects such as antibiotic, antiinflammatory, aid digestion, heat clearing away, detoxifcation, antiallergic, radioprotective, cancer-resisting, except that adopting traditional Chinese prescription, medicative diet for food therapy, also use in functional health-care food modes such as (food such as tea, beverage add).
At present, houttuynine sodium bisulfite has been used for prevention, control and the assisting in preventing and treating of aspect diseases such as anemia, constipation, gastroenteritis, arteriosclerosis, hypertension, diabetes, allergic rhinitis, urticaria, multiple inflammation, cancer both at home and abroad, has indicated that Herba Houttuyniae still has practical DEVELOPMENT PROSPECT on disease is dispelled in nourishing healthy, diseases prevention.
Watermelon crystal
Watermelon crystal is the mature fruit of cucurbitaceous plant Citrullus vulgaris Citrulluis vulgaris Schrad. and the white crystalline powder that Natrii Sulfas processes from strand, and also is a kind of Chinese medicine, and its specific practice is: get fresh Citrullus vulgaris, cut a sheet along base of a fruit head and make top cover, cut out melon pulp and seed, Natrii Sulfas is inserted in the melon, cover top cover, insert firmly with bamboo let, put into earthen basin, build, put the shady and cool ventilation place, when waiting to separate out bloom, under the brush, separating out until no bloom is degree at any time.
The function of watermelon crystal is heat-clearing and toxic substances removing, reducing swelling and alleviating pain with curing mainly.Be used for laryngopharynx swelling and pain, aphtha of the mouth and tongue, gingival swelling and pain or hemorrhage, thrush, infantile thrush and slight burn and scald and wound hemorrhage; Acute and chronic pharyngolaryngitis, tonsillitis, stomatitis, oral ulcer is seen above-mentioned patient.
Summary of the invention
A kind of Chinese medicine composition of preventing and treating oral disease is characterized in that said composition serves as basis side with xylitol, Herba Houttuyniae extract and watermelon crystal, and its parts by weight are:
Xylitol 1-50
Herba Houttuyniae extract 0.01-10
Watermelon crystal 0.1-10
More preferably the parts by weight of compositions are:
Xylitol 1-10
Herba Houttuyniae extract 0.1-5
Watermelon crystal 0.1-5
More preferably the parts by weight of compositions are:
Xylitol 1-5
Herba Houttuyniae extract 0.1-2
Watermelon crystal 0.2-2
Chinese medicine composition of the present invention, one or more in can also other heat-clearing and detoxifying herb of compatibility are to heighten the effect of a treatment; Heat and toxic materials clearing away medicine specifically refers to pear, Flos Lonicerae, Flos Chrysanthemi Indici, Borneolum Syntheticum, Oleum menthae, Mentholum, FRUCTUS TERMINALIAE IMMATURUS, Fructus Momordicae, Indigo Naturalis, Tradescantia albiflora, the Radix Angelicae Dahuricae, Semen Oroxyli, Rhizoma Polygonati Odorati etc.; Wherein survival dose is conventional recommended amounts in each flavor, pear 30-50, Flos Lonicerae 10-15, Flos Chrysanthemi Indici 10-20, Borneolum Syntheticum 0.01-2, Oleum menthae 0.01-2, Mentholum 0.01-2, Borax 0.1-2, FRUCTUS TERMINALIAE IMMATURUS 6-12, Fructus Momordicae 6-12, Indigo Naturalis 1.5-3, Tradescantia albiflora 10-30, Radix Angelicae Dahuricae 6-15, Semen Oroxyli 10-20, Rhizoma Polygonati Odorati 10-20.
Chinese medicine composition of the present invention is in the application that prevents and treats aspect the oral disease, diseases such as control acute and chronic pharyngitis, acute tonsillitis, oral ulcer, stomatitis, gingival swelling and pain, disease is seen: laryngopharynx swelling and pain, hoarseness, laryngalgia, throat moth, erosion of the oral mucosa, aphtha of the mouth and tongue, toothache etc.
Chinese medicine composition of the present invention can be made various dosage forms on the medicament book according to conventional method, specifically refers to tablet, capsule, oral liquid, pill, granule, colloid, syrup, can also add to and make chewing gum and chewable tablet in the food; Its administering mode is oral or topical.
The concrete preparation technology of Herba Houttuyniae extract is as follows: get fresh Herba Houttuyniae, the squeezing extracting juice is standby.
Prescription 1: xylitol 50g, Herba Houttuyniae extract 10g, watermelon crystal 10g, pear 50g
Method for making: concentrating under reduced pressure becomes thick paste after getting the fried juice of pear, adds xylitol, Herba Houttuyniae extract and the watermelon crystal of recipe quantity, adds an amount of chewing gum bodying agent again, is pressed into chewing gum according to a conventional method.
Prescription 2: xylitol 5g, Herba Houttuyniae extract 0.1g, watermelon crystal 0.2g, FRUCTUS TERMINALIAE IMMATURUS 6g, Fructus Momordicae 6g, Oleum menthae 0.1g
Method for making: get FRUCTUS TERMINALIAE IMMATURUS and Fructus Momordicae with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, adds xylitol, Herba Houttuyniae extract, watermelon crystal and the Oleum menthae of recipe quantity, adds auxiliary type agent and correctivess such as an amount of sucrose again, make granule according to a conventional method, repress is made sheet.
Prescription 3: xylitol 10g, Herba Houttuyniae extract 2g, watermelon crystal 5g, Flos Chrysanthemi Indici 20g, Borneolum Syntheticum 0.1g, Mentholum 0.5g
Method for making: Flos Chrysanthemi Indici with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, adds xylitol, Herba Houttuyniae extract, watermelon crystal, Borneolum Syntheticum and the Mentholum of recipe quantity, adds auxiliary type agent and correctivess such as an amount of sucrose again, make granule according to a conventional method, repress is made sheet.
Prescription 4: xylitol 5g, Herba Houttuyniae extract 1g, watermelon crystal 2g, Radix Angelicae Dahuricae 10g, Semen Oroxyli 10g, Rhizoma Polygonati Odorati 10g
Method for making: the Radix Angelicae Dahuricae, Semen Oroxyli, Rhizoma Polygonati Odorati with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, add recipe quantity xylitol, Herba Houttuyniae extract, watermelon crystal, add an amount of auxiliary type agent and correctives again, make oral liquid according to a conventional method.
Prescription 5: xylitol 10g, Herba Houttuyniae extract 5g, watermelon crystal 5g, pear 20g, Flos Lonicerae 10g
Method for making: get the fried juice of pear, Flos Lonicerae use water extraction, both solution merge concentrating under reduced pressure and become thick paste, and xylitol, Herba Houttuyniae extract and the watermelon crystal of adding recipe quantity add an amount of chewing gum bodying agent again, make chewing gum according to a conventional method.
Prescription 6: xylitol 5g, Herba Houttuyniae extract 0.1g, watermelon crystal 0.2g, Indigo Naturalis 3g, Tradescantia albiflora 10g
Method for making: Indigo Naturalis, Tradescantia albiflora with water extraction after, the extracting solution concentrating under reduced pressure becomes thick paste, add recipe quantity xylitol, Herba Houttuyniae extract, watermelon crystal, add an amount of auxiliary type agent and correctives again, make granule according to a conventional method, repress is made tablet.
Pharmacodynamic experiment:
Get prescription 4 and be divided into two groups, looked for the aspiration of oral disease (as: acute and chronic pharyngolaryngitis, tonsillitis, stomatitis, oral ulcer) to try 20 of trenchermans, test-meal (chewing), statistics paresthesia alleviateding time with prescription 5 samples that make.
4 result of the tests of writing out a prescription:
| Paresthesia alleviateding time (hour) | Case load (people) | Total effective rate (%) |
| 0.5 | 4 | 70％ |
| More than 1 hour | 3 |
5 result of the tests of writing out a prescription:
| Paresthesia alleviateding time (hour) | Case load (people) | Total effective rate (%) |
| 0.5 | 3 | 70％ |
| More than 1 hour | 4 |
The result shows that Chinese medicine composition of the present invention has tangible mitigation to the symptom of oral disease.
Claims (8)
1, a kind of Chinese medicine composition of preventing and treating oral disease is characterized in that said composition serves as basis side with xylitol, Herba Houttuyniae extract and watermelon crystal, and its parts by weight are:
Xylitol 1-50
Herba Houttuyniae extract 0.01-10
Watermelon crystal 0.1-10.
2,, it is characterized in that the parts by weight of said composition are according to the described Chinese medicine composition of claim 1:
Xylitol 1-10
Herba Houttuyniae extract 0.1-5
Watermelon crystal 0.1-5.
3,, it is characterized in that the parts by weight of said composition are according to the described Chinese medicine composition of claim 2:
Xylitol 1-5
Herba Houttuyniae extract 0.1-2
Watermelon crystal 0.2-2.
4,, it is characterized in that in can also other heat-clearing and detoxifying herb of compatibility one or more are to heighten the effect of a treatment according to the described Chinese medicine composition of claim 1-3.
5, according to the Chinese medicine composition of any one qualification among the claim 1-4 in the application that prevents and treats aspect the oral disease, be used to prevent and treat diseases such as acute and chronic pharyngitis, acute tonsillitis, oral ulcer, stomatitis, gingival swelling and pain, disease is seen: laryngopharynx swelling and pain, hoarseness, laryngalgia, throat moth, erosion of the oral mucosa, aphtha of the mouth and tongue, toothache etc.
6,, it is characterized in that heat and toxic materials clearing away medicine specifically refers to pear, Flos Lonicerae, Flos Chrysanthemi Indici, Borneolum Syntheticum, Oleum menthae, Mentholum, FRUCTUS TERMINALIAE IMMATURUS, Fructus Momordicae, Indigo Naturalis, Tradescantia albiflora, the Radix Angelicae Dahuricae, Semen Oroxyli, Rhizoma Polygonati Odorati according to the described Chinese medicine composition of claim 4; Wherein survival dose is conventional recommended amounts in each flavor, pear 20-50, Flos Lonicerae 10-15, Flos Chrysanthemi Indici 10-20, Borneolum Syntheticum 0.01-2, Oleum menthae 0.01-2, Mentholum 0.01-2, FRUCTUS TERMINALIAE IMMATURUS 6-12, Fructus Momordicae 6-12, Indigo Naturalis 1.5-3, Tradescantia albiflora 10-30, Radix Angelicae Dahuricae 6-15, Semen Oroxyli 10-20, Rhizoma Polygonati Odorati 10-20.
7,, it is characterized in that and to make various dosage forms on the medicament book according to conventional method that its administering mode is oral or topical according to the described Chinese medicine composition of claim 6.
8, according to the described Chinese medicine composition of claim 7, it is characterized in that specifically referring to tablet, capsule, oral liquid, pill, granule, colloid, syrup, can also add to and make chewing gum and chewable tablet in the food.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610112041 CN1907374A (en) | 2006-08-29 | 2006-08-29 | Chinese medicinal composition for treating oral disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610112041 CN1907374A (en) | 2006-08-29 | 2006-08-29 | Chinese medicinal composition for treating oral disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1907374A true CN1907374A (en) | 2007-02-07 |
Family
ID=37698711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610112041 Pending CN1907374A (en) | 2006-08-29 | 2006-08-29 | Chinese medicinal composition for treating oral disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1907374A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961085A (en) * | 2010-10-15 | 2011-02-02 | 李建华 | Mineralizing teeth-protecting xylitol and preparation method thereof |
| CN103271267A (en) * | 2013-06-09 | 2013-09-04 | 湖南飙歌生物技术有限公司 | Citrulli degelatinatum and xylitol mixture and preparation method and application thereof |
| CN104983933A (en) * | 2015-07-03 | 2015-10-21 | 长沙秋点兵信息科技有限公司 | Chinese herbal medicine throat lozenge containing mirabilitum praeparatum and preparation method of Chinese herbal medicine throat lozenge |
| CN109431882A (en) * | 2018-11-16 | 2019-03-08 | 柳州两面针股份有限公司 | Compound Chinese medicine extract is preparing the application in oral cavity nursing health products |
| CN110151713A (en) * | 2019-05-22 | 2019-08-23 | 苏州知时生物科技有限公司 | Plant oral mucosa fibrosis chewable tablets and preparation method thereof |
-
2006
- 2006-08-29 CN CN 200610112041 patent/CN1907374A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961085A (en) * | 2010-10-15 | 2011-02-02 | 李建华 | Mineralizing teeth-protecting xylitol and preparation method thereof |
| CN101961085B (en) * | 2010-10-15 | 2012-10-03 | 李建华 | Mineralizing teeth-protecting xylitol and preparation method thereof |
| CN103271267A (en) * | 2013-06-09 | 2013-09-04 | 湖南飙歌生物技术有限公司 | Citrulli degelatinatum and xylitol mixture and preparation method and application thereof |
| CN104983933A (en) * | 2015-07-03 | 2015-10-21 | 长沙秋点兵信息科技有限公司 | Chinese herbal medicine throat lozenge containing mirabilitum praeparatum and preparation method of Chinese herbal medicine throat lozenge |
| CN109431882A (en) * | 2018-11-16 | 2019-03-08 | 柳州两面针股份有限公司 | Compound Chinese medicine extract is preparing the application in oral cavity nursing health products |
| CN110151713A (en) * | 2019-05-22 | 2019-08-23 | 苏州知时生物科技有限公司 | Plant oral mucosa fibrosis chewable tablets and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105112265A (en) | Health-care fig wine and preparation method thereof | |
| JP2016532446A (en) | Enbu fermented food or beverage composition | |
| CN103156108A (en) | Fortified food for preventing and treating diabetes mellitus and hypertension diseases | |
| CN108813501B (en) | Health-preserving honey paste with functions of clearing heat, moistening lung, relieving cough, reducing phlegm, relieving asthma and regulating human body functions | |
| JP2018510641A (en) | Health supplements for hair growth promotion, hair loss relief and improvement, blood sugar control, gastrointestinal symptom relief and improvement | |
| KR101826737B1 (en) | A composition containing herbs extract, and manufacturing method of the same | |
| CN1907374A (en) | Chinese medicinal composition for treating oral disease | |
| CN106360664A (en) | Exocarpium Citri Rubrum health food with effects of relieving cough, resisting bacteria, diminishing inflammation, clearing voice and treating pharyngolaryngitis | |
| CN107823293B (en) | Yao medicine external powder for treating oral ulcer and preparation method thereof | |
| CN1861102A (en) | Tablets for promoting prodn. of body-fluid and nourishing throat | |
| CN110063977B (en) | Radix codonopsis and sea buckthorn composite electuary and application thereof | |
| CN101491668B (en) | Composition with blood-sugar reducing function and preparation method thereof | |
| CN105981853A (en) | Nutritional function enriched mild warm tea drink recipe | |
| CN103566312B (en) | Traditional Chinese medicine combination for treating loss of appetite of pigs | |
| CN107050106A (en) | A kind of lozenge for being used to prevent and treat chronic pharyngitis | |
| CN102671058B (en) | Traditional Chinese medicine oral liquid for treatment of vomiting and preparation method thereof | |
| CN1836697A (en) | Candy for larynx | |
| CN101357157A (en) | Preparation for increasing the body fluid | |
| CN106822660A (en) | A kind of Chinese medicine preparation for treating cardiovascular and cerebrovascular disease | |
| CN1772865A (en) | Pumpkin red cordial and its brewing process | |
| KR20180056199A (en) | Manufacturing method of gum for diet containing Moringa Oleifera extract | |
| KR102203094B1 (en) | Composition for preventing and improving menstrual pain and skin troubles | |
| CN118320013B (en) | Traditional Chinese medicine composition for preventing and treating diarrhea of piglets and preparation method thereof | |
| CN1060945C (en) | Kouyangning lozenge | |
| KR100894029B1 (en) | Pharmaceutical composition for the prevention of diabetes from the ginseng flower and pharmaceutical composition for the treatment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20070207 |