CN1977929A - Composition for treating pruritus vulvae disease and its preparing method - Google Patents
Composition for treating pruritus vulvae disease and its preparing method Download PDFInfo
- Publication number
- CN1977929A CN1977929A CNA2005101293481A CN200510129348A CN1977929A CN 1977929 A CN1977929 A CN 1977929A CN A2005101293481 A CNA2005101293481 A CN A2005101293481A CN 200510129348 A CN200510129348 A CN 200510129348A CN 1977929 A CN1977929 A CN 1977929A
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- CN
- China
- Prior art keywords
- disease
- composition
- pruritus vulvae
- fine powder
- borneolum syntheticum
- Prior art date
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- Pending
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- 239000000203 mixture Substances 0.000 title claims abstract description 14
- 208000008350 Pruritus Vulvae Diseases 0.000 title claims abstract description 7
- 206010056530 Vulvovaginal pruritus Diseases 0.000 title claims abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims description 20
- 238000000034 method Methods 0.000 title description 2
- 239000003814 drug Substances 0.000 claims abstract description 10
- 241000628997 Flos Species 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 9
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 6
- 241000282894 Sus scrofa domesticus Species 0.000 claims description 6
- 239000002674 ointment Substances 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 239000000829 suppository Substances 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 239000003937 drug carrier Substances 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000000796 flavoring agent Substances 0.000 claims description 3
- 235000019634 flavors Nutrition 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000000499 gel Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 abstract description 4
- 201000010099 disease Diseases 0.000 description 12
- 208000003251 Pruritus Diseases 0.000 description 5
- 206010046914 Vaginal infection Diseases 0.000 description 5
- 201000008100 Vaginitis Diseases 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 208000004926 Bacterial Vaginosis Diseases 0.000 description 3
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 3
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 3
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethanethiol Chemical compound CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 3
- 230000009545 invasion Effects 0.000 description 3
- 208000004145 Endometritis Diseases 0.000 description 2
- 208000006374 Uterine Cervicitis Diseases 0.000 description 2
- 235000013527 bean curd Nutrition 0.000 description 2
- 206010008323 cervicitis Diseases 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 201000005630 leukorrhea Diseases 0.000 description 2
- 208000007106 menorrhagia Diseases 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 239000002893 slag Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 206010046901 vaginal discharge Diseases 0.000 description 2
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010034240 Pelvic congestion Diseases 0.000 description 1
- 208000003107 Premature Rupture Fetal Membranes Diseases 0.000 description 1
- 206010048245 Yellow skin Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 210000004696 endometrium Anatomy 0.000 description 1
- 210000002219 extraembryonic membrane Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003821 menstrual periods Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 210000003101 oviduct Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 210000004303 peritoneum Anatomy 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 210000004999 sex organ Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a Chinese medicine composition, in the concrete, it is a Chinese medicine composition for curing female pruritus vulvae. Said invention also provides its preparation method.
Description
The present invention relates to a kind of Chinese medicine composition, is the gynopathic Chinese medicine composition of treatment specifically, the invention still further relates to the preparation technology of said composition.
According to the investigation of The World Health Organization (WHO), there is Chinese women more than 70% to suffer from various degree gynaecopathia, married women's gynaecopathia prevalence is more up to more than 90%.The women is 100% gynaecopathia of suffering from various degree almost in life, and wherein gynecological inflammation such as pelvic inflammatory disease, endometritis and cervicitis etc. are women's commonly encountered diseases, account for the out-patient's of gynecological about 89%.Menoxenia in addition, dysmenorrhea also are women's commonly encountered diseases and frequently-occurring diseases.
Leukorrheal diseases are one of commonly encountered diseases, frequently-occurring disease of women, have the saying of " ten woman, nine bands ", and primary disease has that the course of disease is tediously long, the difficult characteristics that heal of delay, has brought many miseries for numerous women.Its pathogenic factor, when modern medicine is thought childbirth or miscarriage, premature rupture of fetal membrane, or the fetal membrane Placenta Hominis is residual, or the intrauterine surgical sterilization is not tight, or unclean woman inspection, or reason such as sexual intercourse in menstrual period, cause courses of infection, make endometrium and adnexa even whole pelvic congestion edema, severe patient can suppurate, and is extensively downright bad.Maximum with damp-heat leukorrhagia, symptom feature is a leukorrhagia amount showed increased, and yellow skin, gas are smelly; Though or amount is few, makings is stench unusually, or with whole body or local symptom.The traditional Chinese medical science roughly is divided into primary disease and insufficiency of the spleenly wet gather into band and become to be with two classes with the instability of kidney-QI of suffering from a deficiency of the kidney.Women's menorrhagia, hold concurrently insufficiency of vital energy and blood card of the damp invasion of lower energizer of menostaxis is more common in pelvic inflammatory disease, endometritis, the cervicitis patient of doctor trained in Western medicine, pelvic inflammatory disease is female sex organ (uterus, fallopian tube, ovary) and connective tissue and pelvic peritoneum on every side, the general designation that be inflamed by bacteria attack is one of commonly encountered disease.Vaginitis is a common gynecological disease, frequently-occurring disease, and the present invention has the critical treatment meaning to the pathological changes that treatment candidal vaginitis, trichomonal vaginitis, bacterial vaginitis cause.
Summary of the invention
Purpose of the present invention just provides a kind of treatment gynecology colpitis Chinese medicine composition of determined curative effect.
Another object of the present invention provides the preparation method of this Chinese medicine composition.
Chinese medicine composition of the present invention is made up of active component or pharmaceutically acceptable carrier, and preferred active component is to be made by following raw materials by weight percent:
Radix Sophorae Flavescentis 8-24 part Cortex Phellodendri 8-24 part Fructus Cnidii 4-12 part Flos Lonicerae 4-12 part Flos Chrysanthemi Indici 8-24 part Fructus Kochiae 1-6 part Radix Angelicae Dahuricae 1-6 part Rhizoma Acori Graminei 1-6 part Borneolum Syntheticum 0.1-4 part Fel Sus domestica unguentum 0.1-4 part
The present invention is made up of Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Flos Lonicerae, Flos Chrysanthemi Indici, the Fructus Kochiae 1, the Radix Angelicae Dahuricae, Rhizoma Acori Graminei, Borneolum Syntheticum, Fel Sus domestica unguentum, has heat clearing and damp drying, a band itching relieving effect of dispelling, be used for damp invasion of lower energizer leukorrhagia, pudendal pruritus disease extremely.Disease is seen: profuse leukorrhea, be the bean curd slag specimen, or yellow as pus, or being yellow foam sample, its gas is stench.Pudendal pruritus, flushing, swelling etc. belong to candidal vaginitis, trichomonal vaginitis, bacterial vaginitis and see above-mentioned symptom person.
The preparation technology that the present invention treats active component in the pruritus vulvae disease compositions is as follows: Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Flos Lonicerae, Flos Chrysanthemi Indici, the Fructus Kochiae, the Radix Angelicae Dahuricae, Rhizoma Acori Graminei eight flavors extract three times with 80% alcohol heating reflux, 2 hours for the first time, second, third time each 1 hour, merge extractive liquid,, filter, filtrate is concentrated into the clear paste that relative density is 1.22～1.28 (50 ℃).Drying is ground into fine powder, again with Fel Sus domestica unguentum powder, Borneolum Syntheticum fine powder mixing, adds appropriate amount of auxiliary materials, makes suppository.
The active component that the present invention treats the pruritus vulvae disease compositions can be prepared into various pharmaceutically acceptable dosage forms with pharmaceutically acceptable carrier, preferred topical administration dosage form.Preferred suppository.
The present invention treat the pruritus vulvae disease compositions have be used for damp invasion of lower energizer leukorrhagia, pudendal pruritus disease extremely.Disease is seen: profuse leukorrhea, be the bean curd slag specimen, or yellow as pus, or being yellow foam sample, its gas is stench.Pudendal pruritus, flushing, swelling etc. belong to candidal vaginitis, trichomonal vaginitis, bacterial vaginitis and see above-mentioned symptom person.
Accompanying drawing: be the process chart that proposes according to the present invention.
Concrete embodiment
Embodiment 1
Take by weighing following raw materials in weight: Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Flos Lonicerae, Flos Chrysanthemi Indici, the Fructus Kochiae, the Radix Angelicae Dahuricae, Rhizoma Acori Graminei eight flavors extract three times with 80% alcohol heating reflux, 2 hours for the first time, second, third time each 1 hour, merge extractive liquid,, filter, filtrate is concentrated into the clear paste that relative density is 1.22～1.28 (50 ℃).Drying is ground into fine powder, again with Fel Sus domestica unguentum powder, Borneolum Syntheticum fine powder mixing, adds appropriate amount of auxiliary materials, makes suppository.
Claims (3)
1, the composition and method of making the same of treatment pruritus vulvae disease, it is characterized in that: with the Chinese medicine material, Radix Sophorae Flavescentis 8-24 part Cortex Phellodendri 8-24 part Fructus Cnidii 4-12 part Flos Lonicerae 4-12 part Flos Chrysanthemi Indici 8-24 part Fructus Kochiae 1-6 part Radix Angelicae Dahuricae 1-6 part Rhizoma Acori Graminei 1-6 part Borneolum Syntheticum 0.1-4 part Fel Sus domestica unguentum 0.1-4 part.
2, according to claims 1, it is characterized in that Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Flos Lonicerae, Flos Chrysanthemi Indici, the Fructus Kochiae, the Radix Angelicae Dahuricae, Rhizoma Acori Graminei eight flavors extract three times with 80% alcohol heating reflux, 2 hours for the first time, second, third time each 1 hour, merge extractive liquid,, filter, filtrate is concentrated into the clear paste that relative density is 1.22～1.28 (50 ℃).Drying is ground into fine powder, again with Fel Sus domestica unguentum powder, Borneolum Syntheticum fine powder mixing, adds appropriate amount of auxiliary materials, makes suppository.
3, according to claims 2, it is characterized in that making the various pharmaceutical carriers of human body acceptable, as pharmaceutical formulations such as tablet, gels.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005101293481A CN1977929A (en) | 2005-12-05 | 2005-12-05 | Composition for treating pruritus vulvae disease and its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005101293481A CN1977929A (en) | 2005-12-05 | 2005-12-05 | Composition for treating pruritus vulvae disease and its preparing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1977929A true CN1977929A (en) | 2007-06-13 |
Family
ID=38129349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005101293481A Pending CN1977929A (en) | 2005-12-05 | 2005-12-05 | Composition for treating pruritus vulvae disease and its preparing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1977929A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104433576A (en) * | 2014-10-27 | 2015-03-25 | 吴清 | Parturient recovery pillow |
| CN105395470A (en) * | 2015-12-02 | 2016-03-16 | 山东皇圣堂药业有限公司 | Vaginal packing adsorptive suppository |
| CN107929619A (en) * | 2017-12-29 | 2018-04-20 | 广西万德药业有限公司 | Lotion for gynaecological imflammation and preparation method thereof |
| CN108079230A (en) * | 2017-12-29 | 2018-05-29 | 广西万德药业有限公司 | Chinese medicine composition containing Chinese knotweed and preparation method thereof |
| CN112263621A (en) * | 2020-11-06 | 2021-01-26 | 杭州纯源生物科技有限公司 | Preparation method of bacteriostatic liquid for private care |
| CN114504619A (en) * | 2022-02-28 | 2022-05-17 | 杭州市第一人民医院 | A kind of traditional Chinese medicine composition for treating atopic dermatitis |
-
2005
- 2005-12-05 CN CNA2005101293481A patent/CN1977929A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104433576A (en) * | 2014-10-27 | 2015-03-25 | 吴清 | Parturient recovery pillow |
| CN105395470A (en) * | 2015-12-02 | 2016-03-16 | 山东皇圣堂药业有限公司 | Vaginal packing adsorptive suppository |
| CN107929619A (en) * | 2017-12-29 | 2018-04-20 | 广西万德药业有限公司 | Lotion for gynaecological imflammation and preparation method thereof |
| CN108079230A (en) * | 2017-12-29 | 2018-05-29 | 广西万德药业有限公司 | Chinese medicine composition containing Chinese knotweed and preparation method thereof |
| CN112263621A (en) * | 2020-11-06 | 2021-01-26 | 杭州纯源生物科技有限公司 | Preparation method of bacteriostatic liquid for private care |
| CN114504619A (en) * | 2022-02-28 | 2022-05-17 | 杭州市第一人民医院 | A kind of traditional Chinese medicine composition for treating atopic dermatitis |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |