CN1951341A - Once forming artificial bone flap used after craniocerebral operation and production method thereof - Google Patents
Once forming artificial bone flap used after craniocerebral operation and production method thereof Download PDFInfo
- Publication number
- CN1951341A CN1951341A CN 200610017294 CN200610017294A CN1951341A CN 1951341 A CN1951341 A CN 1951341A CN 200610017294 CN200610017294 CN 200610017294 CN 200610017294 A CN200610017294 A CN 200610017294A CN 1951341 A CN1951341 A CN 1951341A
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- CN
- China
- Prior art keywords
- main body
- bone
- artificial bone
- skeleton
- polyethylene
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000000988 bone and bone Anatomy 0.000 title claims description 30
- 238000004519 manufacturing process Methods 0.000 title abstract description 5
- 239000000463 material Substances 0.000 claims abstract description 11
- 239000011347 resin Substances 0.000 claims abstract description 9
- 229920005989 resin Polymers 0.000 claims abstract description 9
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims abstract description 8
- 239000004698 Polyethylene Substances 0.000 claims abstract description 8
- 235000010489 acacia gum Nutrition 0.000 claims abstract description 8
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims abstract description 8
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims abstract description 8
- -1 polyethylene Polymers 0.000 claims abstract description 8
- 229920000573 polyethylene Polymers 0.000 claims abstract description 8
- 229920002379 silicone rubber Polymers 0.000 claims abstract description 8
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 14
- 229920000178 Acrylic resin Polymers 0.000 claims description 7
- 239000004925 Acrylic resin Substances 0.000 claims description 7
- 239000001785 acacia senegal l. willd gum Substances 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 235000019359 magnesium stearate Nutrition 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
- 239000004945 silicone rubber Substances 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 2
- 206010030113 Oedema Diseases 0.000 abstract description 7
- 210000004556 brain Anatomy 0.000 abstract description 4
- 238000001356 surgical procedure Methods 0.000 abstract description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 229920000084 Gum arabic Polymers 0.000 abstract 1
- 239000000205 acacia gum Substances 0.000 abstract 1
- NCWQJOGVLLNWEO-UHFFFAOYSA-N methylsilicon Chemical compound [Si]C NCWQJOGVLLNWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 206010048962 Brain oedema Diseases 0.000 description 4
- 210000004761 scalp Anatomy 0.000 description 4
- 208000006752 brain edema Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000002980 postoperative effect Effects 0.000 description 3
- 206010018833 Haematocoele Diseases 0.000 description 2
- 208000005873 Hematocele Diseases 0.000 description 2
- 241000521257 Hydrops Species 0.000 description 2
- 201000004920 hematocele of tunica vaginalis testis Diseases 0.000 description 2
- 210000003625 skull Anatomy 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 208000024779 Comminuted Fractures Diseases 0.000 description 1
- 208000002403 Encephalocele Diseases 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 206010015769 Extradural haematoma Diseases 0.000 description 1
- 208000000386 Hypertensive Intracranial Hemorrhage Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000031809 Subdural Acute Hematoma Diseases 0.000 description 1
- 208000002667 Subdural Hematoma Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002639 bone cement Substances 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
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- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
The invention relates to a method for producing the artificial skeleton in brain surgery. Wherein, it comprises that mixing hydroxypropyl cellulose, methyl silicon rubber, dolomol and medical talcum powder to be fed into particle maker; then mixing it with acroleic acid resin, polyethylene 2000F, skeleton resin, acacia gum and solidifier, to be fed into protrude machine to form material; feeding it into hydraulic shaper to be compressed into skeleton. The invention has high strength and stable property. It can float with the expansion of dropsy brain organism, and it can recover when the dropsy is released.
Description
Technical field:
The invention belongs to medical apparatus manufacturing technology field, is a kind of cranium brain artificial bone flap, and manufacture method.
Background technology:
Behind the neurocranial surgery exenterate bone lobe, edema appears in patient's cranium brain, and present technological means is to carry out the secondary forming operation after edema is eliminated, replant the bone lobe of making into silica gel or bone cement, patient's operative treatment time of being in hospital is long, body and all very painful mentally, and medical expense is also bigger.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of once forming artificial bone flap used after craniocerebral operation.
The present invention provides the method for making this kind bone lobe simultaneously.
Technical scheme of dealing with problems of the present invention is to adopt the bone lobe main body that matches with cranium to make, and bone lobe main body thick middle to edge attenuation gradually, has a connecting hole at least on bone lobe main body.
Bone lobe main body is made by following component material: (consumption is a ratio of weight and number)
Acrylic resin 40-60 polyethylene 2000F 23-28
Hydroxypropyl cellulose 0.5-1.5 methyl silicone rubber 1-2
Skeleton resin 10-20 arabic gum 5-10
Firming agent 1-5 medical talc powder 0.3-0.8
Magnesium stearate 0.5-1.5
The preferred weight portion rate of bone lobe material of main part component is:
Acrylic resin 45-55 polyethylene 2000F 25-26
Hydroxypropyl cellulose 0.5-1.5 methyl silicone rubber 1.2-1.7
Skeleton resin 13-17 arabic gum 6-8
Firming agent 2-4 medical talc powder 0.5-0.7
Magnesium stearate 0.8-1.2
Manufacture method of the present invention is as follows:
To send into the comminutor pelletize after hydroxypropyl cellulose, methyl silicone rubber, magnesium stearate and the medical talc powder mixing; mix with acrylic resin, polyethylene 2000F, skeleton resin, arabic gum and firming agent then; send into extruder again; under 260-280 ℃ of temperature conditions, extrude synthetic former material; former material is sent in the hydro-forming machine mould, and hot forming is made the artificial bone lobe of the present invention under 60-80 ℃ of temperature conditions.
Artificial bone flap of the present invention is used for clinical after zoopery, in 18 examples of clinical practice, acute subdural hematoma 7 examples, and cerebral hernia 2 examples, acute epidural hematoma 4 examples, large tracts of land sunken skull comminuted fracture 1 example, hypertensive cerebral hemorrhage 4 examples, no death, postoperative 10-15 days in the otch top and each row one 1.5CM of place otch of both sides, with staple bone fixation lobe, do not find rejection after the 16 example operations of this group, there is not hematocele hydrops under infection and the scalp, a small amount of hematocele under the 2 routine scalps, tracing observation three months to 2 years, patient's head good looking appearance, the fixation of bone lobe, there is not uncomfortable symptom, the pressure that is a cup too low, the check Cranial Computed Tomography is not all found hydrops under the bone lobe.
Bone lobe mechanical strength height of the present invention, stable performance has certain flexibility, and life-time service does not corrode, invariance, when the postoperative cerebral edema increases the weight of gradually, can float with the bulging of edema cerebral tissue, decompression is fully, after cerebral edema disappears, artificial bone flap can automatically reset, and plays automatic decompressing effect, and it's the pinnacle of cerebral edema phase is past assurance patient smoothness.After treating that edema disappearance cranium positive pressure is normal, with incision of scalp, with staple artificial bone flap is fixed on the skull, sews up the incision, the postoperative intracranial tissue can link together by connecting hole and scalp tissue growth.
Description of drawings:
Fig. 1 is a bone lobe main body sketch map of the present invention;
Fig. 2 is Figure 1A-A cutaway view.
The specific embodiment:
Get and send into the comminutor pelletize after hydroxypropyl cellulose 1 gram, methyl silicone rubber 1.5 grams, magnesium stearate 1 gram and medical talc powder 0.6 mix; mix with acrylic resin 50 grams, polyethylene 2000F25 gram, skeleton resin 15 grams, arabic gum 7 grams and firming agent 3 grams then; send into extruder again; under 270 ℃ of temperature conditions, extrude synthetic former material; former material is sent in the hydro-forming machine mould; hot forming is made the artificial bone lobe of the present invention under 70 ℃ of temperature conditions; through packing, the ethylene oxide sterilizing sterilization gets final product.
Claims (3)
1, a kind of once forming artificial bone flap used after craniocerebral operation is characterized in that: adopt the bone lobe main body that matches with cranium to make, bone lobe main body thick middle to edge attenuation gradually, has a connecting hole at least on bone lobe main body, wherein,
Bone lobe main body is made by following component material:
Acrylic resin 40-60 polyethylene 2000F 23-28
Hydroxypropyl cellulose 0.5-1.5 methyl silicone rubber 1-2
Skeleton resin 10-20 arabic gum 5-10
Firming agent 1-5 medical talc powder 0.3-0.8
Magnesium stearate 0.5-1.5.
2, once forming artificial bone flap used after craniocerebral operation according to claim 1 is characterized in that: bone lobe main body is made by following component material
Acrylic resin 45-55 polyethylene 2000F 25-26
Hydroxypropyl cellulose 0.5-1.5 methyl silicone rubber 1.2-1.7
Skeleton resin 13-17 arabic gum 6-8
Firming agent 2-4 medical talc powder 0.5-0.7
Magnesium stearate 0.8-1.2.
3, once forming artificial bone flap used after craniocerebral operation according to claim 1 and 2 and preparation method thereof is characterized in that: send into the comminutor pelletize after hydroxypropyl cellulose, methyl silicone rubber, magnesium stearate and medical talc powder are mixed; mix with acrylic resin, polyethylene 2000F, skeleton resin, arabic gum and firming agent then; send into extruder again; under 260-280 ℃ of temperature conditions, extrude synthetic former material; former material is sent in the hydro-forming machine mould hot forming under 60-80 ℃ of temperature conditions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610017294 CN1951341A (en) | 2006-11-03 | 2006-11-03 | Once forming artificial bone flap used after craniocerebral operation and production method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610017294 CN1951341A (en) | 2006-11-03 | 2006-11-03 | Once forming artificial bone flap used after craniocerebral operation and production method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1951341A true CN1951341A (en) | 2007-04-25 |
Family
ID=38058033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610017294 Pending CN1951341A (en) | 2006-11-03 | 2006-11-03 | Once forming artificial bone flap used after craniocerebral operation and production method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1951341A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10182802B2 (en) | 2007-03-29 | 2019-01-22 | Nobles Medical Technologies, Inc. | Suturing devices and methods for closing a patent foramen ovale |
| US10194902B2 (en) | 1999-07-02 | 2019-02-05 | Quickpass, Inc. | Suturing device |
-
2006
- 2006-11-03 CN CN 200610017294 patent/CN1951341A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10194902B2 (en) | 1999-07-02 | 2019-02-05 | Quickpass, Inc. | Suturing device |
| US10182802B2 (en) | 2007-03-29 | 2019-01-22 | Nobles Medical Technologies, Inc. | Suturing devices and methods for closing a patent foramen ovale |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |