CN1695743A - Method for preparing Nano antibiosis dressing in medical use - Google Patents
Method for preparing Nano antibiosis dressing in medical use Download PDFInfo
- Publication number
- CN1695743A CN1695743A CN 200510043581 CN200510043581A CN1695743A CN 1695743 A CN1695743 A CN 1695743A CN 200510043581 CN200510043581 CN 200510043581 CN 200510043581 A CN200510043581 A CN 200510043581A CN 1695743 A CN1695743 A CN 1695743A
- Authority
- CN
- China
- Prior art keywords
- layer
- nano
- gauze
- dressing
- super
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003115 biocidal effect Effects 0.000 title claims description 14
- 238000000034 method Methods 0.000 title claims description 8
- 239000002086 nanomaterial Substances 0.000 claims abstract description 12
- 239000000463 material Substances 0.000 claims abstract description 10
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 5
- 238000007598 dipping method Methods 0.000 claims abstract description 4
- 239000010410 layer Substances 0.000 claims description 45
- 239000002105 nanoparticle Substances 0.000 claims description 10
- 239000003242 anti bacterial agent Substances 0.000 claims description 8
- 230000000149 penetrating effect Effects 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 230000003075 superhydrophobic effect Effects 0.000 claims description 7
- 229940088710 antibiotic agent Drugs 0.000 claims description 6
- 229920002521 macromolecule Polymers 0.000 claims description 6
- 229910052709 silver Inorganic materials 0.000 claims description 6
- 239000004332 silver Substances 0.000 claims description 6
- 229910004298 SiO 2 Inorganic materials 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 229910010413 TiO 2 Inorganic materials 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 239000004814 polyurethane Substances 0.000 claims description 3
- 239000002346 layers by function Substances 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 7
- 241000894006 Bacteria Species 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- 239000002120 nanofilm Substances 0.000 abstract 1
- 238000001338 self-assembly Methods 0.000 abstract 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 239000010944 silver (metal) Substances 0.000 description 4
- 239000002131 composite material Substances 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000010946 fine silver Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011858 nanopowder Substances 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
A medical antibacterial nano-dressing material is composed of an antibacterial layer prepared by the self-assembly of antibacterial nano-material onto gauze, a hydrophilic layer prepared by thermal dipping of the gauze while ultraviolet irradiation, a hydrophobic layer prepared from the water vapor permeable parous high-molecular film with a layer of nano-material on its surface, and an external supporting layer. The external water and bacteria can not pass through it but the internal water vapour can.
Description
One, technical field: the preparation method that the present invention relates to a kind of Nano antibiosis dressing in medical use.
Two, background technology: at the development field of advanced medical dressing, nano material has demonstrated the outstanding integrated quality that is better than traditional material.As develop wide spectrum, efficient, safe nano-antibacterial silver granule is used for medical dressing and treats burn and scald, wound, infection suppurates etc.But the particulate cost of preparation fine silver is very high, has restricted it and has used widely.On the other hand, medical dressing is faced with such problem often in application, and promptly how the too much moisture of wound location is removed, and the infiltration that how to prevent outside moisture, guarantees the breathability of dressing simultaneously again.Utilize the characteristic of nano material and come ingenious addressing these problems, still be not reported in conjunction with macromolecule that can penetrating aqueous vapor.Existing solution fiber hydrophilic and hydrophobic method are normal to adopt organic surfactant molecule, but inevitable its safety in utilization problem, especially in medical field.To the unidirectional penetrating problem of aqueous vapor, useful unidirectional group stream organic polymer solves, but needs the used high molecular structure of strict control, and this brings very big difficulty to production technology.Along with the nano material preparation technology and be used for the progressively development of process for modifying surface, the wait in expectation advantageous characteristic that can utilize nano material and solve the problems referred to above by certain treatment technology of medical dressing application is to obtain the medical dressing that integrated quality is better and have complex function.
Three, summary of the invention: purpose of the present invention is exactly the defective that exists at prior art, and a kind of better antibacterial action that has is provided, and internal layer possess hydrophilic property, skin have the preparation method of hydrophobic Nano antibiosis dressing in medical use.
Its technical scheme is: the form that the antibacterial medical dressing of composite nano materials of the present invention is adopted multiple structure combines, this dressing is made up of three one functional layer and one deck supporting layer, ground floor is an antibiotic layer, and this layer is to be undertaken compound by self-assembling method and nano anti-biotic material on the gauze layer; The second layer is a hydrophilic layer, and this layer is by the method for hot dipping stain in conjunction with ultraviolet lighting, with the super hydrophilic treated of nano material work that is compounded on the gauze with gauze; The 3rd layer is hydrophobic layer, and this layer is the macromolecule thin layer with loose structure that can penetrating aqueous vapor, in the compound one deck nano material of this thin layer upper surface, does super-hydrophobic processing then, and outermost is a supporting layer.Nano anti-biotic material is for containing Ag
+SiO
2The ZnO nanoparticle of nanoparticle or coated with silver on surface nano thin-layer.Being compounded in and making super material hydrophilic or super-hydrophobic processing on the gauze is TiO
2Or SiO
2Nano powder.Macromolecule thin layer with loose structure that can penetrating aqueous vapor is a polyurethane.The central authorities of supporting layer have the window of being convenient to ventilate.
The invention has the advantages that:
1, nano anti-biotic material is used for medical dressing and has the incomparable integrated quality of conventional medical antibacterial: wide spectrum, long-acting, safe, superpower sterilization, pollution-free, convenient, can promote wound healing, can not diseaseful drug resistance;
2, can effectively absorb the wound location excessive moisture, prevent that outside moisture from soaking into, but it be outwards penetrating not influence aqueous vapor;
3, the used TiO of super-hydrophobic processing
2Nanoparticle has sterilizing function under daily illumination, thereby can prevent the intrusion of outside antibacterial.
4,, as contain Ag with the composite nano materials for preparing
+SiO
2The ZnO nano-powder of nanoparticle, coated with silver on surface nano thin-layer carries out super hydrophilic and super-hydrophobic processing to medical dressing and absorbs the wound location excess moisture and prevent the wetted problem of outside moisture to solve.
Four, description of drawings: do not have.
Five, specific embodiment:
Embodiment of the present invention are as follows:
Preparation earlier contains Ag
+SiO
2The ZnO nanoparticle of nanoparticle or coated with silver on surface nano thin-layer.
Its funtion part is divided into three layers;
Ground floor:, (as contain Ag by self-assembling technique and nano anti-biotic material with the gauze layer of contact skin
+SiO
2The ZnO nanoparticle of nanoparticle, coated with silver on surface nano thin-layer) carries out compoundly, can bring into play wide spectrum, efficient, safe sterilization, bacteria resistance function, and can promote wound healing, and can not produce resistance;
The second layer: use TiO
2Or SiO
2Nano-powder surpasses the gauze layer of hydrophilic treated (hot dipping stain technology is in conjunction with ultraviolet lighting), and strong absorptive is arranged, and does not have too much moisture to guarantee wound location;
The 3rd layer: have macromolecule (polyurethane) thin layer of loose structure that can penetrating aqueous vapor, upper surface TiO
2Or SiO
2Nano-powder carries out super-hydrophobic processing, but does not influence passing through of aqueous vapor.
Top three layers are attached on the dressing supporting layer with fenestration, and glue connects fixed layer with nonpoisonous polypropylene acid binding agent.Like this, obtain having the medical dressing of composite construction and complex function.
Claims (2)
1, a kind of preparation method of Nano antibiosis dressing in medical use is characterized in that: this dressing is made up of three one functional layer and one deck supporting layer, and ground floor is an antibiotic layer, and this layer is to be undertaken compound by self-assembling method and nano anti-biotic material on the gauze layer; The second layer is a hydrophilic layer, and this layer is by the method for hot dipping stain in conjunction with ultraviolet lighting, with the super hydrophilic treated of nano material work that is compounded on the gauze with gauze; The 3rd layer is hydrophobic layer, and this layer is the macromolecule thin layer with loose structure that can penetrating aqueous vapor, in the compound one deck nano material of this thin layer upper surface, does super-hydrophobic processing then, and outermost is a supporting layer.
2, the preparation method of Nano antibiosis dressing in medical use according to claim 1 is characterized in that: nano anti-biotic material is for containing Ag
+SiO
2The ZnO nanoparticle of nanoparticle or coated with silver on surface nano thin-layer; Being compounded in and making super material hydrophilic or super-hydrophobic processing on the gauze is TiO
2Or SiO
2Nano powder; Macromolecule thin layer with loose structure that can penetrating aqueous vapor is a polyurethane; The central authorities of supporting layer have the window of being convenient to ventilate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510043581 CN1695743A (en) | 2005-05-26 | 2005-05-26 | Method for preparing Nano antibiosis dressing in medical use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510043581 CN1695743A (en) | 2005-05-26 | 2005-05-26 | Method for preparing Nano antibiosis dressing in medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1695743A true CN1695743A (en) | 2005-11-16 |
Family
ID=35348732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510043581 Pending CN1695743A (en) | 2005-05-26 | 2005-05-26 | Method for preparing Nano antibiosis dressing in medical use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1695743A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101631571A (en) * | 2006-11-13 | 2010-01-20 | 奥苏尔公司 | Absorbent structure in an absorbent article |
| CN101721734A (en) * | 2008-10-22 | 2010-06-09 | 威海威高创新有限公司 | Medical calcium alginate antiseptic dressing and preparation method thereof |
| CN109276748A (en) * | 2018-11-28 | 2019-01-29 | 广州润虹医药科技股份有限公司 | One kind prevents adhesion promoting healing antibacterial bearing hydrocolloid dressing and preparation method thereof |
-
2005
- 2005-05-26 CN CN 200510043581 patent/CN1695743A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101631571A (en) * | 2006-11-13 | 2010-01-20 | 奥苏尔公司 | Absorbent structure in an absorbent article |
| CN101631571B (en) * | 2006-11-13 | 2014-04-02 | 奥苏尔公司 | Absorbent structures in absorbent articles |
| CN101721734A (en) * | 2008-10-22 | 2010-06-09 | 威海威高创新有限公司 | Medical calcium alginate antiseptic dressing and preparation method thereof |
| CN109276748A (en) * | 2018-11-28 | 2019-01-29 | 广州润虹医药科技股份有限公司 | One kind prevents adhesion promoting healing antibacterial bearing hydrocolloid dressing and preparation method thereof |
| CN109276748B (en) * | 2018-11-28 | 2021-06-01 | 广州润虹医药科技股份有限公司 | Anti-adhesion healing-promoting antibacterial hydrocolloid dressing and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104758977B (en) | A kind of alginate dressing for treating bedsore and preparation method thereof | |
| CN103239755B (en) | Method for preparing multi-layer composite functional surgical dressing | |
| CN114000349B (en) | Alginate-encapsulated bacterial cellulose composite photothermal antibacterial medical dressing and preparation method thereof | |
| CN109731121B (en) | A kind of preparation method of cellulose and chitosan composite dressing containing mesoporous silica | |
| CN1726782A (en) | Activated carbon fiber-nanometer silver composite medical antibacterial material and preparation method thereof | |
| CN101586309A (en) | Preparation for in-situ compounding simple-substance nano silvery bacteria cellulose membrane | |
| Liu et al. | Research progress on the use of micro/nano carbon materials for antibacterial dressings | |
| CN109568634B (en) | Reduced graphene oxide antibacterial dressing and preparation method thereof | |
| CN103908692B (en) | A kind of composite biological material is applied ointment or plaster and preparation method | |
| CN101721734A (en) | Medical calcium alginate antiseptic dressing and preparation method thereof | |
| CN1165347C (en) | Antibacterial medical dressings made of composite nanomaterials | |
| CN103074777A (en) | Silver-loaded alginate fiber and preparation method thereof | |
| CN1587037A (en) | Active carbon loading silver and its preparing method and use | |
| CN1695743A (en) | Method for preparing Nano antibiosis dressing in medical use | |
| CN111265709A (en) | Pediatric wound protection film for preventing pneumovirus infection and preparation method thereof | |
| CN100336564C (en) | Burn dressing of chitin gel with gradient structure and its preparation | |
| CN104189943B (en) | A kind of medical composite biological material application and preparation method | |
| CN109432479B (en) | Antibacterial hemostatic hydrocolloid oily yarn and preparation method thereof | |
| CN100346840C (en) | Compobite nanometer antibiosis medical dressing | |
| CN110917382A (en) | Preparation method of amnion-spongy chitosan composite double-layer wound dressing | |
| WO2015018349A1 (en) | Hemostatic plaster having a composite structure and preparation method therefor | |
| CN108175873A (en) | It is a kind of for antibacterial medical dressing of Postoperative and anesthesia and preparation method thereof | |
| CN218773997U (en) | Special aseptic degrease gauze piece of ankle joint | |
| CN113975448B (en) | Collagen composite dressing and preparation method thereof | |
| CN1219554C (en) | Artificial skin and producing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |