CN1657116A - Microwave warmer for whole body - Google Patents
Microwave warmer for whole body Download PDFInfo
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- CN1657116A CN1657116A CN 200410046957 CN200410046957A CN1657116A CN 1657116 A CN1657116 A CN 1657116A CN 200410046957 CN200410046957 CN 200410046957 CN 200410046957 A CN200410046957 A CN 200410046957A CN 1657116 A CN1657116 A CN 1657116A
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- microwave
- control circuit
- dimensional motion
- whole body
- motion bed
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- 238000010438 heat treatment Methods 0.000 claims abstract description 25
- 238000012806 monitoring device Methods 0.000 claims description 7
- 230000036760 body temperature Effects 0.000 claims description 6
- 206010028980 Neoplasm Diseases 0.000 abstract description 6
- 208000030507 AIDS Diseases 0.000 abstract description 5
- 201000011510 cancer Diseases 0.000 abstract description 4
- 230000003612 virological effect Effects 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 201000004409 schistosomiasis Diseases 0.000 abstract 1
- 206010020843 Hyperthermia Diseases 0.000 description 10
- 230000036031 hyperthermia Effects 0.000 description 10
- 201000010099 disease Diseases 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- 230000035515 penetration Effects 0.000 description 7
- 238000000015 thermotherapy Methods 0.000 description 5
- 230000006378 damage Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
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- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 210000003491 skin Anatomy 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- LAOOXBLMIJHMFO-UHFFFAOYSA-N 1-[2-(diethylamino)ethylamino]-4-methylthioxanthen-9-one;hydron;chloride Chemical compound Cl.S1C2=CC=CC=C2C(=O)C2=C1C(C)=CC=C2NCCN(CC)CC LAOOXBLMIJHMFO-UHFFFAOYSA-N 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 210000003191 femoral vein Anatomy 0.000 description 2
- 230000036210 malignancy Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 244000045947 parasite Species 0.000 description 2
- 229950000845 politef Drugs 0.000 description 2
- 230000001843 schistosomicidal effect Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 210000003027 ear inner Anatomy 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000012821 model calculation Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 210000003200 peritoneal cavity Anatomy 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 210000001139 rectus abdominis Anatomy 0.000 description 1
- 230000036391 respiratory frequency Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 231100000075 skin burn Toxicity 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 210000001113 umbilicus Anatomy 0.000 description 1
- 210000002417 xiphoid bone Anatomy 0.000 description 1
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- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
A microwave heating apparatus for whole body of a patient is composed of a lift characteristics monitor, a computer, a 3D moving bed with driver, a controller, a microwave source, two microwave emitters with their regulating mechanism, two microwave pulse modulators, and two microwave gathering units. It can be used for treating cancer, AIDS, viral cold and schistosomiasis.
Description
Technical field
The invention belongs to technical field of medical instruments, further be meant to be used for the microwave hyperthermia device that the required whole body of some disease treatment of human body is heated.
Background technology
External the heating of general microwave is that microwave radiometer is aimed at patient body lesions position prolonged exposure, and the heat effect by microwave raises the temperature of irradiated site, reaches the purpose of treatment disease.Because microwave radiation can make the polar molecule in the competent cell bump with friction generates heat in the motion of microwave electromagnetic field high speed when penetrating tissue.Microwave hyperthermia device in the past utilizes this principle that the organism local temperature is raise exactly, and utilizes the difference that pathological tissues and normal structure heat tolerate in the organism and treat disease.As diseases such as the mankind's certain micro-organisms, parasites, because pathogen is to thermo-responsive, when diseased region was heated, microorganism or parasite can be dead because of thermic.The BSD400 heat therapy machine of producing as U.S. BSD company uses the microwave of 915MHZ frequency, and peak power is 400W, has adhered radiation head, and radiant power decays rapidly, the serious and only 3-4cm of the degree of depth that heats of patient's body surface burned; The UHR-2000 type heat therapy machine that Hunan company produces uses the 915MHZ microwave frequency, and peak power reaches 1.2KW, heat at a distance, skin burn reduces, and the degree of depth of heating increases to some extent, but only local oncotherapy there is certain effect, low or invalid to systemic disease efficient.
In order to solve a whole-body hyperthermia difficult problem, the TEMET1000 type whole-body thermotherapeutic machine that U.S. company produces, the design blood of human body is drawn from the femoral vein of a side, in the extracorporeal circulation process, use the microwave principle heating blood, from the input of opposite side femoral vein, make body temperature maintain 41-43 degree centigrade again, but this equipment price costliness, the Therapeutic Method complexity, side effect and complication are many, should not promote.The infrared space of the ETSPACE storehouse that domestic Shenzhen company produces, utilize that infrared ray is external heats, also can make the whole body fervescence, but infrared ray is to human body penetration power extreme difference, heat transfer process is general to body surface organization's damage, and adding needs general anesthesia, and the induction time of heating reaches 2-4 hour, probably cause patient skin to be scalded, the tolerance of patients with advanced cancer also is a problem.
Summary of the invention
The technical problem to be solved in the present invention is, defective at the prior art existence, a kind of microwave whole body heating apparatus is proposed, this device can be to the full metastomium even heating of human body, heat by large tracts of land, deep, by blood circulation heat is sent to whole body and play the whole-body hyperthermia effect, two big major side effects and complication that the body surface that occurs during minimizing is treated is as much as possible simultaneously burnt and patient collapses.
Technical solution of the present invention is, a kind of microwave whole body heating apparatus, referring to accompanying drawing 1, comprise control electronic computer 9 and display 10, control circuit 1, microwave source 2, two microwave radiometers 3, two microwave pulse manipulators 4, two microwave beam bunchers 5, three-dimensional motion bed 6, human body vital sign monitoring device 8, the signal output part that can accurately gather the human body vital sign monitoring device 8 of body temperature is connected with the corresponding signal output port of described electronic computer 9, another road is connected to control circuit 1 to the I/O interface one tunnel of this electronic computer 6 with the drive circuit of described three-dimensional motion bed 6 is continuous, the output port of described control circuit 1 connects the control circuit of microwave source 2, two microwave radiometers 3 are its input with microwave source 2 all, the input of two microwave pulse manipulators 4 its corresponding microwave radiometer 3 delivery outlets respectively links to each other, its outfan is connected with its corresponding microwave beam buncher 5 respectively, described two microwave radiometers 3 be installed in one make it from the 7 body surface 5-48cm of patient on the three-dimensional motion bed apart from adjustable mechanism on.The corresponding patient 7 in both sides can carry out the microwave irradiation place simultaneously about these two microwave radiometers 3 were installed in the three-dimensional motion bed respectively, below output cable wherein is than the long half wavelength of top output cable (16.4CM), according to the microwave phase theory, reach the positive synergistic effect.
Operation principle of the present invention comprises: (1) microwave pulse ripple modulation technique, and make the continuous microwave radiation become the intermittence microwave radiation, increase microwave the living organism tissue is put depth of penetration heating, and reduce the body surface thermal dose, to prevent the skin heat damage; (2) microwave beam forming technigue utilizes the conduction refraction principle of microwave in different medium, makes the microwave energy of unit are increase by 20 times; (3) human body adds temperature technique up and down simultaneously, according to the microwave phase theory, carries out microwave irradiation simultaneously at the human body upper and lower surface, and the below output cable reaches the positive synergistic effect than the long half wavelength of top output cable (16.4CM), and the efficient of heating is obviously increased; (4) even mobile berth makes last patient's trunk short time high strength even heating, and body surface organization's damage probability obviously reduces, and would not influence heating effect because heat retention is imitated in the body.
Because human malignancies, acquired immune deficiency syndrome (AIDS), schistosomicide etc. are systemic disease, having only could more effective treatment with the mode of whole-body hyperthermia.Therefore, the present invention can pass through the microwave exposure organism, makes its whole body fervescence to effectively treating temperature, is 39-41.5 ℃ as malignant tumor Ya Gaowen whole-body hyperthermia, and the standard whole-body hyperthermia is 41.6-43 ℃.
Vital sign monitoring device 8 is mainly the thermocouple temperature measuring apparatus that 8-16 leads film, gather esophagus (representing the thoracic cavity temperature), internal ear (representing the intracranial temperature), rectum (representative temperature in peritoneal cavity) and body surface many places skin temperature, go out partes corporis humani position body temperature by computer human body body temperature Model Calculation, its error＜0.1 ℃.Be furnished with blood pressure, blood oxygen, pulse, respiratory frequency measuring device simultaneously, can in time reflect the changes of vital signs situation.
Adopt the phantom result of the test such as the following table of whole body heating system of the present invention: experiment condition is microwave frequency 915MHZ, output 0-1500W, warm-up time: 5 minutes; The irradiator mould surface distance 25cm that exsomatizes.
Phantom experimental result (Δ t0-5min degree of intensification) is as following table:
| Depth of penetration heating (cm) | Temperature (t0-5min ℃) | t-Max，％ | Regional cm * cm heats |
| ????0 | ????2.84 | ????100％ | ????＞20×20 |
| ????1 | ????2.63 | ????93％ | ????＞20×20 |
| ????2 | ????2.38 | ????83％ | ????20×20 |
| ????3 | ????2.06 | ????70％ | ????19×19 |
| ????4 | ????1.92 | ????63％ | ????17.5×17.5 |
| ????5 | ????1.81 | ????57％ | ????15×15 |
| ????6 | ????1.77 | ????55％ | ????13.5×13.5 |
| ????7 | ????1.66 | ????49％ | ????11.2×11.2 |
| ????8 | ????1.54 | ????42％ | ????11.2×11.2 |
| ????9 | ????1.68 | ????49％ | ????13.5×13.5 |
| ????10 | ????1.82 | ????57％ | ????15×15 |
| ????11 | ????1.98 | ????66％ | ????17.5×17.5 |
| ????12 | ????2.23 | ????77％ | ????19×19 |
| ????13 | ????2.44 | ????84％ | ????20×20 |
| ????14 | ????2.60 | ????92％ | ????＞20×20 |
| ????15 | ????2.82 | ????100％ | ????＞20×20 |
Zoopery: a 70Kg live hog, heated part live hog breast abdominal part.Thermometric position: umbilicus and xiphoid-process line mid point rectus abdominis m. edge.
Experiment condition: microwave rate 915MHZ, output 800W, irradiator from the pig epidermis apart from 25cm, warm-up time 10 minutes.
Experimental result such as following table:
| Depth of penetration heating (cm) | Temperature (℃) | Depth of penetration heating (cm) | Temperature (℃) |
| ????0 | ????43.5 | ????0 | ????43.6 |
| ????1 | ????43.4 | ????1 | ????43.4 |
| ????2 | ????43.2 | ????2 | ????43.3 |
| ????3 | ????42.9 | ????3 | ????43.1 |
| ????4 | ????42.7 | ????4 | ????42.8 |
| ????5 | ????42.6 | ????5 | ????42.7 |
| ????6 | ????42.5 | ????6 | ????42.7 |
| ????7 | ????42.6 | ????7 | ????42.5 |
| ????8 | ????42.4 | ????8 | ????42.4 |
| ????9 | ????42.4 | ????9 | ????42.4 |
| ????10 | ????42.3 | ????10 | ????42.4 |
Above-mentioned experimental result proof is in the 0-20cm depth bounds, and temperature difference is very little, and the different parts temperature is close, proves absolutely that its efficiency of heating surface is obvious, and heat distribution is even, can reach and control effectively treatment temperature.
When using body invention whole body microwave hyperthermia device that patient is treated, patient only feels that the body internal heat generation do not have other incompatible reaction, increases along with fervescence has sweat gland secretion, in time replenish body fluid to patient.This therapy equipment has safe and effective, wide accommodation, and characteristics such as Operation and Maintenance is easy.
In the medical application of the present invention, first-selected human malignancies.Especially middle and terminal cancer has patient 20-40% evident in efficacy.The three-dimensional motion bed is made whole-body hyperthermia during by orbiting motion, is positioned certain point, can do local thermotherapy during directly according to tumor locus.Human other infectious disease such as acquired immune deficiency syndrome (AIDS), viral influenza, schistosomicide etc. also there is certain curative effect.Benign diseases such as nonspecific inflammation such as rheumatoid, rheumatism, nonspecific colonitis, pelvic inflammatory disease, prostate hyperplasia also had better therapeutic effect.
As from the foregoing, the present invention is a kind of microwave whole body heating apparatus.By being heated in uniform large-area deep, trunk position, by blood circulation heat to be sent to whole body again and play the whole-body hyperthermia effect, three-dimensional bed fixed point is aimed at microwave radiometer, can carry out tumor by local thermotherapy and other benign disease thermotherapy.The efficient of heating height has no side effect.
Description of drawings
Fig. 1 is a structured flowchart of the present invention;
Fig. 2 is a microwave beam buncher structural representation.
In Fig. 1～2:
The 1-control circuit, the 2-microwave source,
The 3-microwave radiometer, 4-microwave pulse manipulator,
5-microwave beam buncher, 6-three-dimensional motion bed and control circuit,
7-patient 8-vital sign monitoring device,
The 9-computer, the 10-display.
The specific embodiment
According to the microwave whole body heating apparatus of Fig. 1 and said structure, the power 0-5kw of microwave source 2 is adjustable, and output frequency is 915 or 433MHZ; Microwave radiometer 3 adopts general microwave antenna; Microwave pack 5 is the politef convex lens, base diameter 220mm, convex surface X-axis radius 2505mm, and Y-axis radius 320mm, the arc base plane is arrived apart from 40-200mm in the hyperboloid summit; Vital sign monitoring device 8 is 8 thermocouple temperature measuring apparatus that lead, and other parameter is the general vital sign module in market, and electronic computer 9 adopts the PC computers.
Claims (2)
1, a kind of microwave whole body heating apparatus, comprise control electronic computer (9), display (10), control circuit (1), microwave source (2), two microwave radiometers (3), two microwave pulse manipulators (4), two microwave beam bunchers (5), three-dimensional motion bed (6), human body vital sign monitoring device (8), it is characterized in that, the signal output part that can accurately gather the human body vital sign monitoring device (8) of body temperature is connected with the corresponding signal output port of described electronic computer (9), another road is connected to control circuit (1) to the I/O interface one tunnel of this electronic computer (6) with the drive circuit of described three-dimensional motion bed (6) is continuous, the output port of described control circuit (1) connects the control circuit of microwave source (2), two microwave radiometers (3) are its input with microwave source (2) all, the input of two microwave pulse manipulators (4) its corresponding microwave radiometer (3) delivery outlet respectively links to each other, its outfan is connected with its corresponding microwave beam buncher (5) respectively, described microwave radiometer (3) be installed in one make it from patient (7) body surface 5-48cm on the three-dimensional motion bed apart from adjustable mechanism on.
2, microwave whole body heating apparatus according to claim 1, it is characterized in that, the corresponding patients in both sides (7) can carry out the microwave irradiation place simultaneously about described two microwave radiometers (3) were installed in the three-dimensional motion bed respectively, and below output cable wherein is than the long half wavelength of top output cable (16.4CM).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410046957 CN1657116A (en) | 2004-11-22 | 2004-11-22 | Microwave warmer for whole body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410046957 CN1657116A (en) | 2004-11-22 | 2004-11-22 | Microwave warmer for whole body |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1657116A true CN1657116A (en) | 2005-08-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410046957 Pending CN1657116A (en) | 2004-11-22 | 2004-11-22 | Microwave warmer for whole body |
Country Status (1)
| Country | Link |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2531619A (en) * | 2014-09-12 | 2016-04-27 | Innovarius Ltd | Apparatus and method for providing hyperthermia therapy |
| US11883644B2 (en) | 2017-12-19 | 2024-01-30 | Innovarius Corp. | Apparatus for creating resonant standing waves in biological tissue |
-
2004
- 2004-11-22 CN CN 200410046957 patent/CN1657116A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2531619A (en) * | 2014-09-12 | 2016-04-27 | Innovarius Ltd | Apparatus and method for providing hyperthermia therapy |
| US11324961B2 (en) | 2014-09-12 | 2022-05-10 | Albert Nunez | Apparatus and method for providing hyperthermia therapy |
| US11883644B2 (en) | 2017-12-19 | 2024-01-30 | Innovarius Corp. | Apparatus for creating resonant standing waves in biological tissue |
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