CN1435174A - Urotropine external spray and preparation method thereof - Google Patents
Urotropine external spray and preparation method thereof Download PDFInfo
- Publication number
- CN1435174A CN1435174A CN 03119412 CN03119412A CN1435174A CN 1435174 A CN1435174 A CN 1435174A CN 03119412 CN03119412 CN 03119412 CN 03119412 A CN03119412 A CN 03119412A CN 1435174 A CN1435174 A CN 1435174A
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- CN
- China
- Prior art keywords
- hexamethylenamine
- external spraying
- spraying agent
- gram
- agent according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 title claims abstract description 61
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 239000007921 spray Substances 0.000 title abstract description 25
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 23
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 19
- 238000003756 stirring Methods 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 238000002156 mixing Methods 0.000 claims abstract description 12
- 239000006184 cosolvent Substances 0.000 claims abstract description 6
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 5
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 5
- 239000004094 surface-active agent Substances 0.000 claims abstract description 5
- 238000011049 filling Methods 0.000 claims abstract description 3
- 239000000022 bacteriostatic agent Substances 0.000 claims abstract 2
- 229960004011 methenamine Drugs 0.000 claims description 29
- 238000005507 spraying Methods 0.000 claims description 18
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims description 10
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 7
- 235000010234 sodium benzoate Nutrition 0.000 claims description 7
- 239000004299 sodium benzoate Substances 0.000 claims description 7
- OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 claims description 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 5
- 241000628997 Flos Species 0.000 claims description 4
- 230000000844 anti-bacterial effect Effects 0.000 claims description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 4
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical class CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 3
- XINCECQTMHSORG-UHFFFAOYSA-N Isoamyl isovalerate Chemical compound CC(C)CCOC(=O)CC(C)C XINCECQTMHSORG-UHFFFAOYSA-N 0.000 claims description 3
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims description 3
- 229960004926 chlorobutanol Drugs 0.000 claims description 3
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims description 3
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims description 3
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims description 3
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 claims description 3
- GYCKQBWUSACYIF-UHFFFAOYSA-N o-hydroxybenzoic acid ethyl ester Natural products CCOC(=O)C1=CC=CC=C1O GYCKQBWUSACYIF-UHFFFAOYSA-N 0.000 claims description 3
- 229960000502 poloxamer Drugs 0.000 claims description 3
- 229920001983 poloxamer Polymers 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 235000010199 sorbic acid Nutrition 0.000 claims description 3
- 239000004334 sorbic acid Substances 0.000 claims description 3
- 229940075582 sorbic acid Drugs 0.000 claims description 3
- -1 spans Polymers 0.000 claims description 3
- 229940035024 thioglycerol Drugs 0.000 claims description 3
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims description 3
- 239000005711 Benzoic acid Substances 0.000 claims description 2
- 240000005561 Musa balbisiana Species 0.000 claims description 2
- 235000018290 Musa x paradisiaca Nutrition 0.000 claims description 2
- 235000010233 benzoic acid Nutrition 0.000 claims description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 2
- 229920000136 polysorbate Polymers 0.000 claims description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims description 2
- 239000000341 volatile oil Substances 0.000 claims description 2
- 241000894007 species Species 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 abstract description 4
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 4
- 208000035985 Body Odor Diseases 0.000 abstract description 3
- 206010055000 Bromhidrosis Diseases 0.000 abstract description 3
- 238000011287 therapeutic dose Methods 0.000 abstract description 2
- 208000008454 Hyperhidrosis Diseases 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 230000037315 hyperhidrosis Effects 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 238000007789 sealing Methods 0.000 abstract 1
- 238000012856 packing Methods 0.000 description 10
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 8
- 229920000053 polysorbate 80 Polymers 0.000 description 8
- 229920001214 Polysorbate 60 Polymers 0.000 description 4
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 4
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 4
- 229940113124 polysorbate 60 Drugs 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- NWGKJDSIEKMTRX-MDZDMXLPSA-N Sorbitan oleate Chemical compound CCCCCCCC\C=C\CCCCCCCC(=O)OCC(O)C1OCC(O)C1O NWGKJDSIEKMTRX-MDZDMXLPSA-N 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000010299 hexamethylene tetramine Nutrition 0.000 description 1
- 239000004312 hexamethylene tetramine Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a urotropine external spray and a preparation method thereof, wherein each 1000ml of the external spray contains 1-100 g of urotropine, 100 ml of ethanol with the concentration of 75-95 percent and 700ml of water in balance. And also can be added with 100 ml of cosolvent, 0.1 to 5 g of smell correcting agent, 0.1 to 10 g of bacteriostatic agent, 0.1 to 5 g of antioxidant and 0.1 to 10 g of surfactant. The cosolvent may be propylene glycol or glycerol. The preparation method of the external spray comprises the following steps: dissolving the components in the formula, stirring, mixing, adjusting pH to 4-11, filtering, filling into spray bottle, sealing, packaging, and inspecting to obtain the final product. The spray of the invention is directly sprayed to armpit or hand and foot, is convenient to use, can quantitatively spray therapeutic dose, has the functions of sterilization, convergence and hidroschesis, and can be used for treating hyperhidrosis of hand and foot and bromhidrosis .
Description
Technical field
The present invention relates to a kind of spray, relate in particular to a kind of hexamethylenamine external spraying agent and preparation method.
Background technology
Hexamethylenamine, chemistry hexamethylenetetramine by name, molecular formula C
6H
12N
4Molecular weight 140.19 is the condensation substance of formaldehyde and ammonia, and glossiness crystallization or white crystalline powder are colourless, and almost odorless is sweet at the beginning of the flavor, and the little hardship in back is slightly water-soluble and pure.Meeting fire can burn, and smokeless flame takes place, and has sterilization, anticorrosion, sterilization, and convergence, detumescence, antipruritic, pain relieving, effects such as infection strengthen in sour environment Chinese medicine drug effect, and its effect is not affected the treatment by exudate, pus etc.Also do not have a kind of above-mentioned superior function of hexamethylenamine of utilizing to make external spraying agent at present, its effectiveness is given full play to.
Summary of the invention
The objective of the invention is to: a kind of hexamethylenamine external spraying agent and preparation method are provided.
The every 1000ml of external spraying agent of the present invention contains 1-100 gram hexamethylenamine, and concentration is the ethanol 100-700ml of 75%-95%, and surplus is a water.
Also can add cosolvent 100-250ml in the above-mentioned prescription of external spraying agent of the present invention, cosolvent can be propylene glycol or glycerol.
Also contain in the above-mentioned prescription of external spraying agent of the present invention to rectify and smell agent 0.1-5 gram.Rectify and to smell agent and can be: Fructus Citri Limoniae, Fructus Citri tangerinae, Fructus Foeniculi, Fructus Amomi Rotundus, Pericarpium Citri junoris, Flos Caryophylli, Flos Rosae Rugosae, Herba Menthae, Radix Glycyrrhizae, volatile oil and flavoring banana essence that Cortex cinnamomi japonici (Ramulus Cinnamomi) etc. are purified, flavoring orange essence, Fructus Citri Limoniae essence, apple essence.
Also contain in the above-mentioned prescription of external spraying agent of the present invention: antibacterial 0.1-10 gram.Antibacterial is one of benzoic acid, sodium benzoate, ethyl hydroxybenzoate, methyl hydroxybenzoate, sorbic acid, chlorobutanol.
Also contain antioxidant 0.1-5 gram in the above-mentioned prescription of external spraying agent of the present invention, surfactant 0.1-10 gram.Antioxidant is one of sodium sulfite salt, thioglycerol, thiourea, THIOGLYCOL, 2,6 ditertbutylparacresols and BHA or two or more.Surfactant can be selected one of Tweens, spans, poloxamer or two or more for use.
The preparation method of external spraying agent of the present invention is: each component dissolving in will filling a prescription, stir, mixing is regulated pH value and is filtered to 4-11, fill is sealed in spray bottle, packing, check finished product.
Spray of the present invention is directly to aim at oxter or brothers' spray delivery, and is easy to use, can quantitatively spray therapeutic dose, and using dosage is accurate, has sterilization, convergence, and anti-hidropoiesis can be used for the treatment of acrohyperhidrosis and bromhidrosis (bromhidrosis).
The specific embodiment
The present invention is described in detail below in conjunction with embodiment.
Embodiment 1:
Get hexamethylenamine 100g, 95% ethanol 700ml, propylene glycol 200ml, sodium benzoate 5g, Fructus Citri Limoniae essence 0.1ml, add water to 1000ml.
Preparation method is as follows:
With the hexamethylenamine propylene glycol, the alcoholic solution stirring and dissolving is even, adds distilled water then, and regulating pH value is 8, adds sodium benzoate, and Fructus Citri Limoniae essence, stir, filter the intermediate check, be filled into spray bottle, seal, outer package is finished product after the assay was approved.
Hexamethylenamine is made spray: can directly aim at the affected part spray delivery, and dosage is accurate, improves antibacterial activity.
Embodiment 2:
Get hexamethylenamine 10 grams, 2, two pairs of butyl paracresol of 6-, 0.1 gram, tween 80 20.0 grams, propylene glycol 100ml, Oleum menthae 5 grams, 95% medicinal alcohol 600ml, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check 1% hexamethylenamine spray finished product.
Embodiment 3:
Get hexamethylenamine 50 grams, glycerol 250ml, ethyl hydroxybenzoate 5 grams, 95% medicinal alcohol 600ml, Oleum Rosae Rugosae 0.2 gram, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 4:
Get hexamethylenamine 80 grams, glycerol 200ml, sorbester p17 5 grams, 95% medicinal alcohol 700ml, sorbic acid 3 grams, Oleum Caryophylli 0.2 gram, sodium pyrosulfite 5 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 5:
Get hexamethylenamine 10 grams, propylene glycol 250ml, Tween 80 2 grams, 75% medicinal alcohol 600ml, Fructus Citri Limoniae oil 0.5 gram, thioglycerol 5 grams, poloxamer 2 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 6:
Get hexamethylenamine 5 grams, glycerol 200ml, Tween 80 2 grams, 75% medicinal alcohol 600ml, apple essence 0.1 gram, chlorobutanol 2 grams, thiourea 5 grams, polysorbate60 2 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 7:
Get hexamethylenamine 70 grams, glycerol 180ml, Tween 80 2 grams, 75% medicinal alcohol 650ml, Fructus Foeniculi essence 3 grams, THIOGLYCOL 0.8 gram, thiourea 5 grams, polysorbate60 2 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 8:
Get hexamethylenamine 70 grams, propylene glycol 180ml, Tween 80 2 grams, 75% medicinal alcohol 650ml, flavoring orange essence 5 grams, sodium benzoate 2 grams, 2,6 ditertbutylparacresols, 3 grams, Tween 80 2 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 9:
Get hexamethylenamine 100 grams, propylene glycol 180ml, polysorbate60 2 grams, 75% medicinal alcohol 650ml, Oleum menthae 5 grams, sodium benzoate 2 grams, BHA 4 grams, Tween 80 2 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Embodiment 10:
Get hexamethylenamine 100 grams, glycerol 250ml, polysorbate60 2 grams, 95% medicinal alcohol 550ml, Cortex cinnamomi japonici (Ramulus Cinnamomi) quintessence oil 5 grams, sodium benzoate 2 grams, BHA 2 grams, thiourea 2 grams, Tween 80 2 grams, each component dissolving, stirring, mixing, adding distil water is to total amount 1000ml.Regulate pH value and filter to 4-11, fill is sealed in spray bottle, packing, check finished product.
Claims (8)
1, a kind of hexamethylenamine external spraying agent is characterized in that: every 1000ml contains 1-100 gram hexamethylenamine, and concentration is the ethanol 100-600ml of 75%-95%, and surplus is a water.
2, hexamethylenamine external spraying agent according to claim 1 is characterized in that: also can add cosolvent 100-250ml, cosolvent can be propylene glycol or glycerol.
3, hexamethylenamine external spraying agent according to claim 1 and 2 is characterized in that: contain to rectify and smell agent 0.1-5 gram.
4, hexamethylenamine external spraying agent according to claim 3 is characterized in that: rectify and to smell agent and can be: Fructus Citri Limoniae, Fructus Citri tangerinae, Fructus Foeniculi, Fructus Amomi Rotundus, Pericarpium Citri junoris, Flos Caryophylli, Flos Rosae Rugosae, Herba Menthae, Radix Glycyrrhizae, volatile oil and flavoring banana essence that Cortex cinnamomi japonici (Ramulus Cinnamomi) etc. are purified, flavoring orange essence, Fructus Citri Limoniae essence, apple essence.
5, hexamethylenamine external spraying agent according to claim 1 and 2 is characterized in that: bacteriostatic agent 0.1-10 gram.
6, hexamethylenamine external spraying agent according to claim 5 is characterized in that: antibacterial is one of benzoic acid, sodium benzoate, ethyl hydroxybenzoate, methyl hydroxybenzoate, sorbic acid, chlorobutanol.
7, hexamethylenamine external spraying agent according to claim 1 and 2, it is characterized in that: contain antioxidant 0.1-5 gram, surfactant 0.1-10 gram, antioxidant is one of sodium sulfite salt, thioglycerol, thiourea, THIOGLYCOL, 2,6 ditertbutylparacresols and BHA or two or more, surfactant can be selected one of Tweens, spans, poloxamer or two or more for use
8, the preparation method of hexamethylenamine external spraying agent according to claim 1 and 2 is characterized in that: each component species dissolving in will filling a prescription, stir, mixing is regulated pH value 4-11 and is filtered, fill is sealed, the color dress, check finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03119412 CN1435174A (en) | 2003-03-12 | 2003-03-12 | Urotropine external spray and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03119412 CN1435174A (en) | 2003-03-12 | 2003-03-12 | Urotropine external spray and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1435174A true CN1435174A (en) | 2003-08-13 |
Family
ID=27634518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03119412 Pending CN1435174A (en) | 2003-03-12 | 2003-03-12 | Urotropine external spray and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1435174A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100370985C (en) * | 2006-06-24 | 2008-02-27 | 周俊堂 | Externally applied sprayer formulation for sweat control and deodorization |
| CN103690980A (en) * | 2013-11-13 | 2014-04-02 | 东莞市日友汽车用品有限公司 | Aromatic sterilization purification spraying agent and preparation method thereof |
| CN105250348A (en) * | 2015-11-18 | 2016-01-20 | 重庆市中药研究院 | Tripterygium hypoglaucum (level) hutch root external preparation for relieving swelling and pain as well as preparation method and application thereof |
| CN108186568A (en) * | 2018-03-16 | 2018-06-22 | 南京精德丰新材料科技有限公司 | A kind of nursing spray and application thereof |
| CN109288720A (en) * | 2017-07-24 | 2019-02-01 | 刘崇庆 | Deodorant composition and process for producing the same |
| CN110934159A (en) * | 2019-12-24 | 2020-03-31 | 贵州贵安精准医学研究院股份有限公司 | Development and application of natural bactericidal spray |
-
2003
- 2003-03-12 CN CN 03119412 patent/CN1435174A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100370985C (en) * | 2006-06-24 | 2008-02-27 | 周俊堂 | Externally applied sprayer formulation for sweat control and deodorization |
| CN103690980A (en) * | 2013-11-13 | 2014-04-02 | 东莞市日友汽车用品有限公司 | Aromatic sterilization purification spraying agent and preparation method thereof |
| CN105250348A (en) * | 2015-11-18 | 2016-01-20 | 重庆市中药研究院 | Tripterygium hypoglaucum (level) hutch root external preparation for relieving swelling and pain as well as preparation method and application thereof |
| CN105250348B (en) * | 2015-11-18 | 2019-05-14 | 重庆市中药研究院 | It is a kind of for the colguhoumia root external preparation of swelling and pain relieving, preparation method and applications |
| CN109288720A (en) * | 2017-07-24 | 2019-02-01 | 刘崇庆 | Deodorant composition and process for producing the same |
| CN108186568A (en) * | 2018-03-16 | 2018-06-22 | 南京精德丰新材料科技有限公司 | A kind of nursing spray and application thereof |
| CN110934159A (en) * | 2019-12-24 | 2020-03-31 | 贵州贵安精准医学研究院股份有限公司 | Development and application of natural bactericidal spray |
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