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CN1365664A - Medicine for removing vegetation from human body and its preparing process and application - Google Patents

Medicine for removing vegetation from human body and its preparing process and application Download PDF

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Publication number
CN1365664A
CN1365664A CN 02101987 CN02101987A CN1365664A CN 1365664 A CN1365664 A CN 1365664A CN 02101987 CN02101987 CN 02101987 CN 02101987 A CN02101987 A CN 02101987A CN 1365664 A CN1365664 A CN 1365664A
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medicine
tissue
trichloroacetic acid
dehydration
hemorrhoid
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CN 02101987
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Chinese (zh)
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王怀琛
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Abstract

A medicine for removing the vegetation from human body is an aqueous solution of trichloroacetic acid, which is prepared from water and dehydrated trichloroacetic acid in Wt. ratio of 1:(18-24). Its advantages include high effect, no residual scar, no untoward effect, and low poison.

Description

Excrescent medicine of a kind of removal human body and its production and application
One, technical field:
The present invention relates to a kind of medicine of removing human body vegetation and tissue, also relate to the preparation method of described medicine and this medicine in a organized way and the application of vegetation removal in institute.
Two, background technology:
At present, remove tissue both at home and abroad and excrescent method has surgical method, physical method and chemical method.Surgical risk is big, and cicatrix is arranged; The physical method cycle is long and efficient is undesirable or the cycle short and stay cicatrix; Chemicals strips off method because of less application such as safety problems, and the medicine of application has phenol, silver nitrate, trichloroacetic acid usually, and the former two seldom uses because of the scope that big toxicity is arranged and strip off is less.Have on the textbook and put down in writing: " the trichloroacetic acid solution with 33.3% or 50% (weight ratio) concentration has than severe corrosive, often with pain.Be applied to the wart surface with the cotton swab dip in liquid medicine, once a day, 2-3 time the wart body removed.This agent is unsuitable for the wart body and merges person in blocks, and the little wart body of isolated minority can be used this method, and normal skin avoids contacting this agent." (" sexually transmitted disease (STD) diagnosis and pharmacotherapeutics "; Beijing science tech publishing house in August, 1999 front page); put down in writing on another textbook: " the trichloroacetic acid solution of 80%-90% (weight ratio) concentration, be applied on the wart body, repeated drug taking needs indirect 1 week " (" skin cypridology "-Guangdong science and technology publishing house, 97 year April the 3rd edition).33.3% or 50% or the trichloroacetic acid solution of 80%-90% (weight ratio) concentration, the vegetation removal that is applied in skin, mucosal tissue has certain effect, but only can remove the vegetation of thin layer tissue, invalid to deep layer, also show following defectives: it is slow 1) to solidify (crustization) speed, needs 5 to 10 seconds kinds or longer time just can work; 2) tissue removal effect difference and slow can only be removed thin layer tissue, to thicker (>0.05cm) body the removal speed of the piece of tissue of big (cube of>0.1cm) is slow or invalid, generally need continuous several times use (more than 3 times).Though body surpasses the removal of the above cube piece of tissue of 0.5cm and still is difficult to remove through repeatedly using, thereby the scope and the size of removal tissue are very restricted; 3) safety is relatively poor, during medication, occurs medicinal liquid easily and reach the tendency that the bottom is permeated in a big way around site of action, causes intact skin and mucosa and subcutaneous connective tissue to come to harm; 4) anastalsis is poor, and anastalsis is unhappy, especially when tissue has more transudate, then can't stop blooding.Concentration is that the preparation of the trichloroacetic acid solution of 33.3%-90% (weight ratio) is: take by weighing 33.3-90 gram dehydration trichloroacetic acid earlier, add in 100 ml waters, constantly shake, it is dissolved fully promptly get the trichloroacetic acid solution that concentration is 33.3%-90% (weight ratio).Range of application is little wart body thin layers such as (condyloma acuminatum) (<0.05cm) removal of tissue on freckle, verruca plana and the mucosa on the skin.
Three, summary of the invention:
The purpose of this invention is to provide a kind of medicine of removing multiple class vegetation of human body and tissue on a large scale.
Another object of the present invention is to provide the compound method of the described medicine trichloroacetic acid of ultrahigh concentration.
Further aim of the present invention provide the various tissues of ultrahigh concentration trichloroacetic acid solution on skin, mucosa and beyond its hetero-organization such as the application of the removal of the vegetation of serous coat, internal organs etc., tissue.
Technical scheme of the present invention is to be CCl with molecular formula 3COOH, structural formula is The dehydration trichloroacetic acid be mixed with 1800% to 2400% aqueous solution, i.e. water by weight: dehydration trichloroacetic acid ratio is 100: 1800 to 100: 2400.The proportion of this solution>1.3 grams per milliliters.
Its process for preparation is: 100 ml waters are added in the container that fills 100 gram dehydration trichloroacetic acids, (adopting 70 ℃ of immersion method hydrotropy water temperatures), fully shake, make its dissolving, add 100 gram dehydration trichloroacetic acids again, mix molten, continue to add 100 gram dehydration trichloroacetic acids, mix moltenly again, carry out successively, add 1800 grams to 2400 gram dehydration trichloroacetic acids and mix the ultrahigh concentration trichloroacetic acid solution that molten back forms 1800% to 2400% (weight ratio) until reaching.
The inventor finds medicine of the present invention, can not only remove the freckle on the skin, verruca plana, little wart body (condyloma acuminatum) on the mucosa, can also remove the nevus on the skin, birthmark, capillary hemangioma, rind gall, verruca vulgaris, molluscum contagiosum, tatoo, eyebrow tattooing, cicatrix, syringoma, hemorrhoid on the mucosa (comprise internal hemorrhoid, external hemorrhoid and mixed hemorrhoid), genital herpes, the internal organs mucosa (comprises that the cervix uteri harness is mashed, cervical polyp, condyloma acuminata of vagina), the huge verruca vulgaris of subcutaneous connective tissue, huge blue nevus, the vegetation and the tissue at mashed and other positions of human body of the cervicitis harness of serous coat aspect.
The present invention compared with prior art has following excellent results:
1, safety is good, and medicine of the present invention does not find to occur the general untoward reaction as yet through animal experiment and clinical practice thousand examples, through the organized renewing good (generally i.e. healing in 10 days) of effect; 2, the effect degree and the range size depth are easy to control.Described medicine only acts on medicinal liquid to the curing of organizing (crustization) and is applied to part, around the site of action tissue and deep layer permeate voluntarily (as dip in the crust face thickness getting a medicine and on arm skin, form<0.05cm) with toothpick, so can decide drug effect scope and effect degree by the amount and the site of action control of drug use, many to quantity, body is thinner, it is particularly suitable that the tissue that is difficult for excision and has beauty treatment to require is removed, enantiomorph is bigger, thicker removal organizes available bamboo tooth pick gently to prick, gently choose and make medicinal liquid be covered with this tissue, the tissue that all this medicinal liquids enter can be removed, and does not remove at the place of not entering; 3, applied range, described medicine shows through the application of animal experiment and clinical thousand routine various disease, described medicine not only can be applicable in the tissue removal of human body skin, mucosa, can also be applied in the human body vegetation beyond the skin, mucosa and the removal of tissue, can be widely used in related organization's removal work of aspects such as surgery, department of eye, gynecological, oncology, department of dermatologry, medical cosmetology section, STD Dept.; 4, wound recovers, and no sequel, described medicine have the effect of the hamartoplasia of promotion.Wound with back formation, because of forming fine and close hard crust face fast, not having the inflammatory material again oozes out, generally need not antiinflammatory and handle, do not infect, not inflammation, mucosa can be fully recovered in five days, skin can be fully recovered in ten days, do not form cicatrix, minority has certain pigmentation in a short time, promptly disappears voluntarily in general 1-2 month and takes off; 5, the quick-acting haemostatic powder effect is arranged, described medicine has the effect that promptly ends of using to hemorrhage with oozing of blood; 6, it is fast to solidify (crustization) effect, and described medicine is short to the time of organizing the generation effect, and general 1-3 is that visible acting surface bleaches in second, overstrike crust face behind half an hour-1 hour, and crust comes off in 3-10 days.
Toxicological experiment and clinical practice test: 1, animal experiment, ten of white mice are selected in a, skin surface test, smear described medicine in the scope of skin area 5%, and 0.01 milliliter of dosage is not seen toxic reaction; B, oral toxicity test are pressed-13.4 gram/kilogram administrations of 1.34 grams with 500 times of described medicine dilute with waters, divide to pour into from the mice mouth for three times, do not see death; By-1.34 gram/kilogram standard administrations of 0.67 gram, with 500 times of described medicine dilute with waters, death is not seen in the disposable celiac injection; 2, human trial, skin usable floor area 3cm 2, 0.05 milliliter of dosage is not seen toxic reaction (5 of volunteers); Mucosa usable floor area 3cm 2, dosage is not seen toxic reaction (10 of volunteers) for 0.03 milliliter; Serous coat usable floor area 5cm 2, 0.1 milliliter of dosage is not seen toxic reaction (5 of volunteers).
Pharmacological experiment: we in use carry out a, anesthesia substantially in the following manner: smear or be injected at into treatment sites with 2% benefit card or 0.1% tetracaine solution earlier, make its topical anesthesia or local anesthesia; B, medication: dip in the sterilization bamboo tooth pick and to get a little described medicine and spread upon and need to remove the position, organize thicklyer as removal, available toothpick is gently pricked the limit dip in liquid medicine and is smeared, and medicinal liquid is affacted needs to remove the whole of tissue; C, desensitization: dip in cotton swab and to get drug desensitization and be coated in and remove tissue, prevent anaphylaxis; D, decrustation are healed: take good care of the above-mentioned tissue of medication, treat its incrustation, come off naturally, general wound surface need not antiphlogistic antibacterial and handles, as big (the straight warp>1cm), consider to use the anti-inflammatory ointment external of wound surface.1, animal experiment: use 2 age white mice, adopt said method, its result is white mouse dermoreaction situation: bleach-the browning color-no inflammatory exudate-crust block edge is clear; The skin healing nature, 5 to 7 days decrustation time, the healed surface skin surface is bright and clean.2, human trial: the tuerculoderma situation is identical with the white mice situation; As processing to flat nevus, pressing preceding method uses, note being coated with bundle deep black tissue with the toothpick dip in liquid medicine, make medicinal liquid reach black deeply and organize root,, adopt same procedure the processing of protruding nevus, attention toothpick dip in liquid medicine is gently pricked the nevus body makes medicinal liquid infiltrate tissue, the skin healing nature, the decrustation time is about 7 days, healing place skin is bright and clean; To verruca plana, use preceding method, note the wart body of straight warp>0.3cm, gently draw together the surface with the toothpick dip in liquid medicine, the little wart body of straight warp<0.3cm gets final product with the light duck eye of pricking of toothpick dip in liquid medicine, and the decrustation time is 7-10 days, and skin is bright and clean; To condyloma acuminatum, use as stated above, notice that the wart body is coated with full medicinal liquid up and down, directly once through 1cm and thick 0.5cm left and right sides wart body and function medicine, can all come off in 3 days, the above wart body of thick 1cm needs continuous use (be medication every day once), with medication behind the normal saline flush away crust piece, comes off fully in general 3-5 days before the medication next time.
Use described medicine to adopt following steps at the position of painless nerves such as human body viscera: 1, tissue is removed in medication: described medicine is directly spread upon needs the tissue removed, as organizes can gently prick more deeply medicinal liquid is infiltrated.2, desensitization: during described medicine that internal organs use, be " the excitation reaction " that prevents to occur, should be before medication, the medicine of use antianaphylaxis earlier is as the dexamethasone injection etc.3, the healing that comes off: the internal organs in outer siphunculus chamber are arranged, and the effect tissue can be discharged, and does not have the viscera tissue of outer siphunculus, and effect is organized and can be formed the machine piece and retain.
In human trial, the described medicine of dermal application, 1-3 forms white crust sheet second, becomes brown crust sheet after 20 minutes, the crust sheet recovery from illness that comes off after 7-10 days; The described medicine of mucosal use, 1-2 forms white crust sheet second, becomes brown crust sheet (some position mucosa keeps white crust sheet always) after 20 minutes to 60 minutes, and recovery from illness came off after 3 to 5 days; Serous coat is used described medicine, and 1-2 forms white crust sheet second, becomes brown crust sheet after 20 minutes to 1 hour, and recovery from illness came off after 3-5 days.
The clinic trial information slip;
Classification Kind The treatment number Effective number Effective percentage Remarks
The skin class Nevus 584 people 584 people 100%
Go to tatoo 3 people 3 people 100%
Freckle 136 people 136 people 100%
Go eyebrow tattooing 4 people 4 people 100%
Verruca plana 47 people 47 people 100%
Capillary hemangioma 19 people 19 people 100%
Skin vegetations 10 people 10 people 100%
Birthmark 6 people 6 people 100%
Cicatrix 5 people 5 people 100%
The mucosa class The genitals condyloma acuminatum 202 people 202 people 100%
Genital herpes 9 people 9 people 100%
The serous coat class Cervical polyp 6 people 6 people 100%
Cervicitis 15 people 15 people 100%
Other Hemorrhoid (inside and outside hemorrhoid, mixed hemorrhoid) 21 people 21 people 100%
Four, embodiment:
The following examples can make those skilled in the art more fully understand the present invention, but do not limit the present invention in any way.
Embodiment 1
Take by weighing 100 gram water, add 100 gram dehydration trichloroacetic acids, dissolve in temperature is 70 ℃ water-bath, the back adds 100 gram dehydration trichloroacetic acids, mix molten, add 100 gram dehydration trichloroacetic acids again, mix moltenly, carry out successively, add 100 gram dehydration trichloroacetic acids for the 18 time, mix molten 1800% the trichloroacetic acid solution of being, under 50 ℃ of temperature, be filled into bottle and be finished product.The transparent liquid of the colourless or faint yellow slightly abnormal flavour of this finished product.
Case 1: patient face sees that filbert blurring is commonly called as freckle, especially differs in size in reaching all needle point to the grain of rices of nose now, is distributed symmetrically garden shape, ovum garden shape.Its therapeutic process: smear speckle with 2% lignocaine, local surfaces anesthesia 10 minutes; The back with the sterilization toothpick dip in get above-mentioned preparation medicine a little, dub speckle in vain; Quick the smearing by a part of the powerful detoxifcation of reuse, in case local anaphylaxis, giving free rein in 3-7 days comes off, and scratches, and advises that the drug effect place does not get wet in 2 hours.No cicatrix after coming off, skin is bright and clean.
Embodiment 2
Take by weighing 100 gram water, add 100 gram dehydration trichloroacetic acids, dissolve in temperature is 70 ℃ water-bath, the back adds 100 gram dehydration trichloroacetic acids, smear molten, add 100 gram dehydration trichloroacetic acids again, mix moltenly, carry out successively, add 100 gram dehydration trichloroacetic acids for the 19 time, mix molten 1900% the trichloroacetic acid solution of being, under 50 ℃ of temperature, be filled into bottle and be finished product.Colourless or the faint yellow scent of slightly of this finished product is transparent liquid.
Case 2: patient face sees that to be dispersed in melanotic nevus a plurality of, and is as the Semen phaseoli radiati, little of the needle point size greatly, do not have special performance.Its therapeutic process: smear melanotic nevus with 2% lignocaine, do topical anesthesia; The back with the sterilization toothpick dip in get above-mentioned preparation medicine a little, click and enter melanotic nevus in vain, giving free rein to comes off, and advises not get wet in two hours; Quick the smearing around the melanotic nevus of the powerful detoxifcation of reuse is in case local anaphylaxis.After six days, check that the melanotic nevus of original place comes off fully, and vestige is arranged slightly, disappears in one month.
Embodiment 3
Take by weighing 100 gram water, add 100 gram dehydration trichloroacetic acids, in the water-bath of 70 ℃ of temperature, dissolve, the back adds 100 gram dehydration trichloroacetic acids, mixes moltenly, adds 100 gram trichloroacetic acids again, mix moltenly, carry out successively, add 100 gram dehydration trichloroacetic acids the 20 time, mix molten 2000% the trichloroacetic acid solution that promptly forms, under 50 ℃ of temperature, be filled into bottle and be product, the colourless or faint yellow slightly abnormal flavour of this product, be transparent liquid, have stronger corrosivity.
Case 3: the epimegetic condyloma acuminatum takes place in patient's penis coronary sulcus towards periphery, long 5cm, and wide 4cm, the front portion has shown the black lump, the thick 2cm that reaches, the rear portion is obvious cauliflower form condyloma acuminatum lump, thick about 1.5cm, equal annular distribution, foreskin takes off and contracts, and does not have big wart body substantially.Aforementioned bulk wart body has lymph fluid to flow out, and is epimegetic condyloma acuminatum piece.Its therapeutic process: smear the wart surface with 2% lignocaine, do topical anesthesia, continue and smear with a large amount of (1 milliliter) above-mentioned preparation medicines, wrap up with iodine fluorine gauze the back, the reuse normal saline cleaned and repeated above-mentioned Therapeutic Method next day or the 3rd day, continuous drop antibiotics during the treatment, normal saline, antiviral agents; Shared medicine is 8 times in 10 days, and the back once is dispersed in the wart body with removing every medication in 7 days, discontinues medication after 18 days, and huge wart body comes off, and does not see recurrence.
Case 4: patient's row is expanded cloudy the inspection, and see cervical erosion III ° (directly through about 3cm), the cervix uteri mouth has the big polyp of a Semen Glycines, and palace body enlargement is obvious, and leucorrhea is many.Its therapeutic process: remove cervical mucus with sterilized cotton ball, continue with the obliterating of above-mentioned preparation medicine, treat into white crust face, the cervix uteri mouth has oozing of blood, dips in cotton swab and gets said medicine and smear, and just can stop blooding, and adds anti-inflammatory agent.Be separated by 3 days for the first time with treatment for the second time, for the second time be separated by 7 days with the 4th treatment for the third time and for the third time, through 4 treatments, the disease healing.
Case 5: patient's labium majus has the big wart body of 5 place Semen Glyciness, and nympha has tens big wart bodies of Semen phaseoli radiati, is furnished with ten many places wart bodies on the vaginal wall, it is in blocks that the wart body has, and the big wart body of a Semen Glycines is arranged on the cervix uteri mouth, companion's cervical erosion, above wart body has is cauliflower form, and being of having is block.Above wart body is condyloma acuminatum, its therapeutic process: intravaginal wart body directly dips in the sterilization toothpick and gets above-mentioned a little spot printing of preparation medicinal liquid, extravaginal wart body and function 2% lignocaine is smeared, do topical anesthesia, after 15 minutes, with the sterilization toothpick dip in get above-mentioned preparation medicine a little, spot printing wart body, treatment for the first time was separated by 3 days with treatment for the second time, treatment for the second time was separated by 7 days with treatment for the third time, was separated by 6 days with the 4th treatment for the third time, was separated by then and checked once in 10 days, remove recurrence wart body with medicine, all lose recurrence wart body after two months.Follow up a case by regular visits to do not see so far the recurrence and heal.
Embodiment 4
Take by weighing 100 gram water, add 100 gram dehydration trichloroacetic acids, in temperature is 70 ℃ water-bath, dissolve, the back adds 100 gram dehydration trichloroacetic acids, mixes moltenly, adds 100 gram trichloroacetic acids again, mix molten, carry out successively, the 20 once adds 100 gram dehydration trichloroacetic acids, mixes molten 2100% the trichlorine caproic acid aqueous solution that promptly gets, under 50 ℃ of temperature conditions, be filled into bottle, colourless or the faint yellow slightly abnormal flavour of this product is transparent liquid, has stronger corrosivity.
Case 6: the superfluous greatly rawhide effluent of an outstanding skin Semen Glycines is seen on patient's cervical region right side, and matter is soft, the normal colour of skin.Its therapeutic process: smear the vegetation surface with 2% lignocaine, do topical anesthesia; And with the sterilization toothpick dip in get above-mentioned preparation medicinal liquid a little, click and enter vegetation surface and root to white; Quick the smearing around it of the powerful detoxifcation of reuse to prevent local anaphylaxis, comes off after ten days, the no cicatrix of check after month.
Embodiment 5
Take by weighing 100 gram water, add 100 gram dehydration trichloroacetic acids, dissolve in temperature is 70 ℃ water-bath, the back adds 100 gram dehydration trichloroacetic acids, mix molten, add 100 gram dehydration trichloroacetic acids again, mix moltenly, carry out successively, the 20 secondary adds 100 gram dehydration trichloroacetic acids, mix molten 2200% the trichloroacetic acid solution that promptly gets, under 50 ℃ of temperature conditions, be filled into bottle and be finished product.Colourless or the faint yellow slightly abnormal flavour of this finished product is transparency liquid, has stronger corrosivity.
Case 7: patient's face is dispersed in verruca plana totally 8 places, and the maximum is about 1cm.Its therapeutic process: dip in cotton swab and to get 2% lignocaine and smear the verruca plana surface, do topical anesthesia, wait to absorb to doing about 10 minutes; The back with the sterilization toothpick dip in get above-mentioned preparation medicine a little, the pricking method verruca plana; Dip in cotton swab then and get quick the smearing of powerful detoxifcation, in case local anaphylaxis; After one week, giving free rein to comes off, and advises in two hours not get wet.
Embodiment 6
Take by weighing 100 gram water, add 100 gram dehydration trichloroacetic acids, dissolve in temperature is 70 ℃ water-bath, the back adds 100 gram dehydration trichloroacetic acids, mix molten, add 100 gram dehydration trichloroacetic acids again, mix moltenly, carry out successively, add 100 gram dehydration trichloroacetic acids for the 23 time, mix molten 2300% the trichloroacetic acid solution that promptly obtains, under 50 ℃ of temperature conditions, be filled into bottle and be finished product.Colourless or the faint yellow slightly abnormal flavour of this finished product is transparent liquid, has stronger corrosivity.
Case 8: patient's right leg side is seen small broad bean size enclosed mass, has more than a year, and garden shape, rough surface, keratinization, matter is hard, lark, no conscious sympton, idol has tenderness, examines to be verruca vulgaris.Its therapeutic process: dip in cotton swab and to get 2% lignocaine and smear the wart body, do topical anesthesia; After 10 minutes, with the sterilization toothpick dip in get above-mentioned preparation medicine a little, put perverse wart body, meet hemorrhagely, promptly end with this medicine, the some back is with powerful quick the smearing in case local anaphylaxis of detoxifying; After 7 days, operation is once carried out the secondary treatment as stated above again, after going 7 days, comes off naturally, and verruca vulgaris is comparatively obstinate to need twice medication treatment to cure fully, more the no cicatrix in back.
Embodiment 7
Identical with embodiment 6 preparation methoies.Just add 100 gram dehydration trichloroacetic acids, mix and promptly obtain 2400% trichloroacetic acid solution after molten, under 50 ℃ temperature conditions, be filled into bottle and be finished product too at the 24 time.Colourless or the faint yellow slightly abnormal flavour of this finished product is transparency liquid, has stronger corrosivity.
Case 9: the blue nevus of this case is directly through 1cm, and thickness 0.5cm is the scleroma shape, doubts to be the initial stage of cancerating.After 2% lignocaine topical anesthesia, to prick to choose with the bamboo tooth pick dip in liquid medicine and make medicinal liquid until the soft place of blue nevus root, whole nevus body and periphery all are coated with medicinal liquid, this orchid nevus came off fully in the 10th day, handle in conjunction with antiinflammatory, the open sore part heals fully in one month, and no abnormality seen is so far visited by Sui.

Claims (4)

1, a kind of medicine of removing human body vegetation and tissue is a trichloroacetic acid solution, its water: the dehydration trichloroacetic acid is 100: 1800-2400 (weight ratio) promptly 1: 18-24, the just trichloroacetic acid solution of 1800%-2400% (weight ratio concentration).
2, the preparation method of claim 1 medicine is:
A) pour water and dehydration trichloroacetic acid into same container, stir;
B) adopt (70 ℃) water-bath hydrotropy;
C) add the dehydration trichloroacetic acid successively in proportion, stirring and dissolving promptly gets described medicine;
D) under 50 ℃ of temperature conditions, be filled into bottle.
3, the described medicine of claim 1 is removed the vegetation at (treatment) skin, mucosa, subcutaneous tissue, connective tissue, serous coat, organs and tissues and other positions of human body and the application in the tissue in preparation.
4,, specifically remove nevus, birthmark, capillary hemangioma, rind gall, verruca vulgaris, molluscum contagiosum, condyloma acuminatum, go to tatoo, go eyebrow tattooing, remove cicatrix, the application in the syringoma, huge verruca vulgaris, huge blue nevus, genital herpes, hemorrhoid (internal hemorrhoid, external hemorrhoid and mixed hemorrhoid), cervical erosion, cervical polyp, condyloma acuminata of vagina in preparation according to the application of the described medicine of claim 3.
CN 02101987 2002-01-23 2002-01-23 Medicine for removing vegetation from human body and its preparing process and application Pending CN1365664A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103442692A (en) * 2011-04-04 2013-12-11 环绕护肤(私人)有限公司 The treatment of viral infections

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103442692A (en) * 2011-04-04 2013-12-11 环绕护肤(私人)有限公司 The treatment of viral infections
CN103442692B (en) * 2011-04-04 2016-05-18 环绕护肤(私人)有限公司 The treatment of viral infection

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