CN1340353A - Orally-applied medicine for treating hepatism and its preparing process - Google Patents
Orally-applied medicine for treating hepatism and its preparing process Download PDFInfo
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- CN1340353A CN1340353A CN 00123604 CN00123604A CN1340353A CN 1340353 A CN1340353 A CN 1340353A CN 00123604 CN00123604 CN 00123604 CN 00123604 A CN00123604 A CN 00123604A CN 1340353 A CN1340353 A CN 1340353A
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- radix
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- rhizoma
- herba
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- 239000003814 drug Substances 0.000 title claims abstract description 22
- 238000000034 method Methods 0.000 title description 3
- 239000000843 powder Substances 0.000 claims abstract description 30
- 239000007788 liquid Substances 0.000 claims abstract description 13
- 238000007796 conventional method Methods 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 238000002360 preparation method Methods 0.000 claims description 15
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 14
- 239000000706 filtrate Substances 0.000 claims description 14
- 239000010231 banlangen Substances 0.000 claims description 13
- 208000019423 liver disease Diseases 0.000 claims description 12
- 239000002994 raw material Substances 0.000 claims description 10
- 229940126701 oral medication Drugs 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 238000001556 precipitation Methods 0.000 claims description 4
- 235000021551 crystal sugar Nutrition 0.000 claims description 3
- 210000000582 semen Anatomy 0.000 claims description 3
- 239000007779 soft material Substances 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 239000002270 dispersing agent Substances 0.000 claims description 2
- 235000014347 soups Nutrition 0.000 claims description 2
- 208000019425 cirrhosis of liver Diseases 0.000 abstract description 4
- 230000001154 acute effect Effects 0.000 abstract description 3
- 230000002440 hepatic effect Effects 0.000 abstract description 3
- 239000000463 material Substances 0.000 abstract description 3
- 206010016654 Fibrosis Diseases 0.000 abstract description 2
- 230000007882 cirrhosis Effects 0.000 abstract description 2
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 241001071795 Gentiana Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 description 10
- 210000004185 liver Anatomy 0.000 description 6
- 231100000283 hepatitis Toxicity 0.000 description 5
- 206010003445 Ascites Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000003203 everyday effect Effects 0.000 description 4
- 206010008909 Chronic Hepatitis Diseases 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
- 206010023126 Jaundice Diseases 0.000 description 2
- 102000003929 Transaminases Human genes 0.000 description 2
- 108090000340 Transaminases Proteins 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010007882 Cellulitis Diseases 0.000 description 1
- 241000218176 Corydalis Species 0.000 description 1
- 241001269238 Data Species 0.000 description 1
- 241000587839 Gymnotheca Species 0.000 description 1
- 102000011842 Serrate-Jagged Proteins Human genes 0.000 description 1
- 108010036039 Serrate-Jagged Proteins Proteins 0.000 description 1
- 241000205578 Thalictrum Species 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
An orally applied Chinese medicine for treating acute or chronic hepatitides, cirrhosis and hepatic hydroperitoneum is prepared from 16 Chinese medicinal materials including Chinese gentian root, phoenix-tail fern, oriental wormwood, barbat skallcap, giant knotweed rhizome, etc. through preparing oral liquid and powder by conventional methods. Its advantages include high effective rate up to 95, high cure rate up to 85% or more, no recurrence and low cost.
Description
The present invention relates to a kind of medicine for the treatment of hepatopathy, particularly relating to the Chinese herbal medicine is the medicine of the treatment hepatopathy made of raw material.
Hepatopathy is a kind of commonly encountered diseases, frequently-occurring disease, and doctor trained in Western medicine has little effect to this medication, and the medical expense costliness, and the somebody does not have the money treatment and gets killed too early, and therefore many patients adopt the tcm methods treatment.At present, the Chinese medicine preparation of disclosed treatment hepatopathy is more, is that to adopt Chinese herb medicine be that 8 flavor Chinese herbal medicine such as meadowrue corydalis leaf, Carapax Trionycis, Chinese gymnotheca herb, Spora Lygodii, serrate cshloranthus stem and leaf are mixed and form for " powder medicine for strengthening spleen and softening liver " patent application of CN1167636A as publication number; And for example publication number is " liver invigorating granule " patent application of CN1239662A, and the Chinese herbal medicine of choosing is Herba Artemisiae Scopariae, Herba Sedi, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Pericarpium Citri Reticulatae, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Poria, Radix Angelicae Sinensis, Radix Curcumae, Fructus Schisandrae Chinensis etc.Also having the Chinese herbal and crude drugs preparations such as the publication number of some treatment hepatitis B in addition is CN1171257A, CN1233501A, CN1233487A patent application.Because various pharmaceutical preparation composition of raw materials differences, curative effect also just is not quite similar.
The objective of the invention is to propose a kind of cure mainly various acute or chronic hepatitis, yellow cellulitis hepatitis, liver cirrhosis, hepatic ascites and pure Chinese medicinal preparations.
Main technical schemes of the present invention: Radix Gentianae, Herba Pteridis Multifidae, Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Herba Scutellariae Barbatae, Radix et Rhizoma Rhei (processed), Radix Bupleuri, Poria, Radix Salviae Miltiorrhizae, Carapax Trionycis, Radix Isatidis, the Radix Rehmanniae, Radix Crataegi, Radix et rhizoma lygodii, Fructus Gardeniae root, short component in thousand are made oral liquid and powder.
Oral drugs of the present invention are medicaments of being made by the following weight proportion raw material:
Radix Gentianae 5-20 Herba Pteridis Multifidae 5-20 Herba Artemisiae Scopariae 50-180
Herba Scutellariae Barbatae 20-80 Rhizoma Polygoni Cuspidati 20-80 Radix et Rhizoma Rhei (processed) 10-40
Carapax Trionycis 8-40 Radix Bupleuri 10-40 Poria 12-50
Radix Salviae Miltiorrhizae 15-50 Radix et rhizoma lygodii 70-300 Radix Isatidis 15-60
Radix Rehmanniae 25-100 Fructus Gardeniae root 20-80 Radix Crataegi 30-120
Short 30-120 in thousand
Described medicament is oral liquid and powder.
Described oral liquid is to be made by the proportioning raw material of following weight:
Radix Gentianae 5-10 Herba Pteridis Multifidae 5-10 Herba Artemisiae Scopariae 50-90
Herba Scutellariae Barbatae 20-40 Rhizoma Polygoni Cuspidati 20-40 Radix et Rhizoma Rhei (processed) 10-20
Carapax Trionycis 8-20 Radix Bupleuri 10-20 Poria 12-25
Radix Salviae Miltiorrhizae 15-25 Radix et rhizoma lygodii 70-150 Radix Isatidis 15-30
Radix Rehmanniae 25-50 Fructus Gardeniae root 20-40 Radix Crataegi 30-60
Short 30-60 in thousand
The concrete preparation method of described oral liquid:
Carapax Trionycis, Radix Bupleuri, Poria, Radix Salviae Miltiorrhizae, Radix et rhizoma lygodii, Radix Isatidis, the Radix Rehmanniae, Fructus Gardeniae root, Radix Crataegi, decocted according to a conventional method after short being mixed in proportion in thousand: water is covered powder, decoct 1/3 (volume) to water consumption, filter, obtain filtrate for the first time, water is with covering powder again, decoct 1/2 (volume) to water consumption, filter, obtain filtrate for the second time, be concentrated into 1/2 (volume) of twice mixed liquor after at last above-mentioned twice filtrate being mixed, precipitation, 2 hours after-filtration, bottling, sterilization promptly is made into oral liquid.
Described powder is to be made by the raw material of following weight ratio:
Radix Gentianae 10-20 Herba Pteridis Multifidae 10-20 Herba Artemisiae Scopariae 90-180
Herba Scutellariae Barbatae 40-80 Rhizoma Polygoni Cuspidati 40-80 Radix et Rhizoma Rhei (processed) 20-40
Carapax Trionycis 20-40 Radix Bupleuri 20-40 Poria 25-50
Radix Salviae Miltiorrhizae 25-50 Radix et rhizoma lygodii 150-300 Radix Isatidis 30-60
Radix Rehmanniae 50-100 Fructus Gardeniae root 40-80 Radix Crataegi 60-100
Short 60-120 in thousand
The preparation method of described powder:
The preparation process of powder: with Radix Gentianae, Herba Pteridis Multifidae, Herba Artemisiae Scopariae, Herba Scutellariae Barbatae, Rhizoma Polygoni Cuspidati, Radix et Rhizoma Rhei (processed), Carapax Trionycis, Radix Bupleuri, Poria, Radix Salviae Miltiorrhizae, Radix et rhizoma lygodii, Radix Isatidis, the Radix Rehmanniae, the Fructus Gardeniae root, Radix Crataegi, decoct according to a conventional method after the short mixing in thousand: water is covered powder, decoct 1/3 (volume) to water consumption, filter, obtain filtrate for the first time, water is covered powder again, decoct 1/2 (volume) filtration to water consumption, obtain filtrate for the second time, be concentrated into 1/2 (volume) of twice mixed liquor after at last above-mentioned twice filtrate being mixed, precipitation, filter, obtain spissated dose, the Semen phaseoli radiati powder of weight such as adding and medicine soup or dried Spora Lygodii powder and an amount of crystal sugar stir into soft material again, after drying or drying, are ground into fine powder and promptly make dispersant.
Therapeutic Method: one month is a course of treatment.The patient with severe symptoms, preferably first half of the month is obeyed oral liquid, every day 2 times, each 200 grams, back two weeks clothes powder, every day 2 times, each 22-25g; The patient with slight symptoms, preferably first half of the month is obeyed powder, every day 2 times, each 22-25g, back two weeks clothes oral liquid, every day 2 times, each 200 grams.If back to front can not affect the treatment yet.
Advantage of the present invention:
For many years, product of the present invention is used for the treatment of various acute and chronic hepatitis, jaundice type hepatitis, liver cirrhosis, the hundreds of examples of hepatic ascites patient, all obtains satisfied effect, and patient's medication length is two courses of treatment then, and just take a turn for the better or recovery from illness short then half course of treatment.Total effective percentage for the treatment of various hepatitis reaches 95%, cure rate reaches more than 85%, the transaminase reduces to that 40 following persons reach 95%, jaundice eliminating rate 100%, and various ill symptomses disappear.Visit more than 1 year not that the recidivist reaches 85%, the HBSAg negative conversion rate reaches 36%, anti-HBC-1gM negative conversion rate reaches more than 80%.Table 1 provide nearly 300 routine various hepatitis clinical datas (in the table " improvement " but still be in stable state before though sx after being meant two courses of treatment of taking medicine is pressed, kowtowed and do not have big pain, and liver matter is softening, and ascites obviously goes down, and the transaminase reduces to 40-50; " healing " is meant that various ill symptomses disappear, and every reaction all reaches the clinical cure standard, can operate as normal and life, do not have the recidivist in 1 year).
Prescription of the present invention is comprehensive, have heat clearing away, detoxifcation, soothing the liver, regulate the flow of vital energy, the effect of spleen invigorating, dehumidifying blood stasis dispelling, and stability is strong, has no side effect, and can improve the immune function of self effectively, therefore the difficult recurrence after more.The used raw material resources of product of the present invention in addition are abundant, and cheap, processing method is simple, are a kind of oral drugs that are subjected to the treatment hepatopathy that the patient welcomes deeply.
Further specify characteristics of the present invention below by concrete example.
Example 1
This example is the preparation oral liquid.
Material quantity: Radix Gentianae 8 grams, Herba Pteridis Multifidae 7 grams, Herba Artemisiae Scopariae 70 grams, Herba Scutellariae Barbatae 35 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix et Rhizoma Rhei (processed) 18 grams, Carapax Trionycis 16 grams, Radix Bupleuri 14 grams, Poria 18 grams, Radix Salviae Miltiorrhizae 18 grams, Radix et rhizoma lygodii 120 grams, Radix Isatidis 22 grams, the Radix Rehmanniae 35 grams, Fructus Gardeniae root 30 grams, Radix Crataegi 50 grams, short 50 grams in thousand.
Preparation process: all raw materials mixing are placed in the container, and according to a conventional method, twice decoction with being concentrated into 620g after twice filtrate mixing, precipitates 2 hours and refilters, bottling, and sterilization gets final product.
Example 2
This example is a preparation powder.
Material quantity: Radix Gentianae 16 grams, Herba Pteridis Multifidae 15 grams, Herba Artemisiae Scopariae 140 grams, Herba Scutellariae Barbatae 65 grams, Rhizoma Polygoni Cuspidati 60 grams, Radix et Rhizoma Rhei (processed) 30 grams, Carapax Trionycis 30 grams, Radix Bupleuri 30 grams, Poria 36 grams, Radix Salviae Miltiorrhizae 35 grams, Radix et rhizoma lygodii 230 grams, Radix Isatidis 48 grams, the Radix Rehmanniae 76 grams, Fructus Gardeniae root 60 grams, Radix Crataegi 85 grams, short 90 grams in thousand.
Preparation process: press the method for example 1, decoct and to be concentrated into 560 grams after twice, twice filtrate is mixed, add with concentrated solution equivalent weight Semen phaseoli radiati powder and 250 gram crystal sugar again and stir into soft material, oven dry is ground into fine powder and is powder.
Table 1
| Illness | The number of taking medicine | Take a turn for the better | Cure | Invalid |
| Oxyhepatitis | 90 people | 8 people | 82 people | |
| Chronic hepatitis | 120 people | 16 people | 91 people | 13 people |
| Yellow liver hepatitis | 71 people | 71 people | ||
| Cirrhosis | 9 people | 3 people | 6 people | |
| Liver ascites | 7 people | 6 people | 1 people |
Claims (6)
1. oral medicine for the treatment of hepatopathy is characterized in that it being the medicament of being made by the following weight proportion raw material:
Radix Gentianae 5-20 Herba Pteridis Multifidae 5-20 Herba Artemisiae Scopariae 50-180
Herba Scutellariae Barbatae 20-80 Rhizoma Polygoni Cuspidati 20-80 Radix et Rhizoma Rhei (processed) 10-40
Carapax Trionycis 8-40 Radix Bupleuri 10-40 Poria 12-50
Radix Salviae Miltiorrhizae 15-50 Radix et rhizoma lygodii 70-300 Radix Isatidis 15-60
Radix Rehmanniae 25-100 Fructus Gardeniae root 20-80 Radix Crataegi 30-120
Short 30-120 in thousand
2. according to the oral drugs of the described treatment hepatopathy of claim 1, it is characterized in that described medicament is oral liquid and powder.
3. according to the oral drugs of claim 1 or 2 described treatment hepatopathys, it is characterized in that it being to make oral liquid by the following weight proportion raw material:
Radix Gentianae 5-10 Herba Pteridis Multifidae 5-10 Herba Artemisiae Scopariae 50-90
Herba Scutellariae Barbatae 20-40 Rhizoma Polygoni Cuspidati 20-40 Radix et Rhizoma Rhei (processed) 10-20
Carapax Trionycis 8-20 Radix Bupleuri 10-20 Poria 12-25
Radix Salviae Miltiorrhizae 15-25 Radix et rhizoma lygodii 70-150 Radix Isatidis 15-30
Radix Rehmanniae 25-50 Fructus Gardeniae root 20-40 Radix Crataegi 30-60
Short 30-60 in thousand
4. according to the oral drugs of claim 1 or 2 described treatment hepatopathys, it is characterized in that it being that the following weight proportion raw material is made powder:
Radix Gentianae 10-20 Herba Pteridis Multifidae 10-20 Herba Artemisiae Scopariae 90-180
Herba Scutellariae Barbatae 40-80 Rhizoma Polygoni Cuspidati 40-80 Radix et Rhizoma Rhei (processed) 20-40
Carapax Trionycis 20-40 Radix Bupleuri 20-40 Poria 25-50
Radix Salviae Miltiorrhizae 25-50 Radix et rhizoma lygodii 150-300 Radix Isatidis 30-60
Radix Rehmanniae 50-100 Fructus Gardeniae root 40-80 Radix Crataegi 60-100
Short 60-120 in thousand
5. the preparation method of the oral medicine of the described hepatopathy of claim 3, the preparation process that it is characterized in that oral liquid: Carapax Trionycis, Radix Bupleuri, Poria, Radix Salviae Miltiorrhizae, Radix et rhizoma lygodii, Radix Isatidis, the Radix Rehmanniae, the Fructus Gardeniae root, Radix Crataegi, decoct according to a conventional method after short being mixed in proportion in thousand: water is covered powder, decoct 1/3 (volume) to water consumption, filter, obtain filtrate for the first time, water is covered powder again, decoct 1/2 (volume) to water consumption, filter, obtain filtrate for the second time, be concentrated into 1/2 (volume) of twice mixed liquor after at last above-mentioned twice filtrate being mixed, precipitation, 2 hours after-filtration, bottling, sterilization promptly is made into oral liquid.
6. the preparation method of the oral drugs of the described treatment hepatopathy of claim 4, the preparation process that it is characterized in that powder: with Radix Gentianae, Herba Pteridis Multifidae, Herba Artemisiae Scopariae, Herba Scutellariae Barbatae, Rhizoma Polygoni Cuspidati, Radix et Rhizoma Rhei (processed), Carapax Trionycis, Radix Bupleuri, Poria, Radix Salviae Miltiorrhizae, Radix et rhizoma lygodii, Radix Isatidis, the Radix Rehmanniae, the Fructus Gardeniae root, Radix Crataegi, decoct according to a conventional method after the short mixing in thousand: water is covered powder, decoct 1/3 (volume) to water consumption, filter, obtain filtrate for the first time, water is covered powder again, decoct 1/2 (volume) filtration to water consumption, obtain filtrate for the second time, be concentrated into 1/2 (volume) of twice mixed liquor after at last above-mentioned twice filtrate being mixed, precipitation, filter, obtain spissated dose, the Semen phaseoli radiati powder of adding and medicine soup equivalent weight or dried Spora Lygodii powder and an amount of crystal sugar stir into soft material again, after drying or drying, be ground into fine powder and promptly make dispersant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00123604 CN1340353A (en) | 2000-08-29 | 2000-08-29 | Orally-applied medicine for treating hepatism and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00123604 CN1340353A (en) | 2000-08-29 | 2000-08-29 | Orally-applied medicine for treating hepatism and its preparing process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1340353A true CN1340353A (en) | 2002-03-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00123604 Pending CN1340353A (en) | 2000-08-29 | 2000-08-29 | Orally-applied medicine for treating hepatism and its preparing process |
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| Country | Link |
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| CN (1) | CN1340353A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1305504C (en) * | 2004-09-29 | 2007-03-21 | 刘言正 | Medicine for treating hepatitis |
| CN100355428C (en) * | 2004-01-05 | 2007-12-19 | 玄振玉 | Preparation technology and use of Chinese herbal medicine phoenix-tail fern |
| CN103599429A (en) * | 2013-10-14 | 2014-02-26 | 何海银 | Traditional Chinese medicine for treating hepatitis A |
| CN105193958A (en) * | 2015-09-24 | 2015-12-30 | 三穗县回春堂中医诊所 | Medicine for treating liver cirrhosis and preparation method thereof |
-
2000
- 2000-08-29 CN CN 00123604 patent/CN1340353A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100355428C (en) * | 2004-01-05 | 2007-12-19 | 玄振玉 | Preparation technology and use of Chinese herbal medicine phoenix-tail fern |
| CN1305504C (en) * | 2004-09-29 | 2007-03-21 | 刘言正 | Medicine for treating hepatitis |
| CN103599429A (en) * | 2013-10-14 | 2014-02-26 | 何海银 | Traditional Chinese medicine for treating hepatitis A |
| CN105193958A (en) * | 2015-09-24 | 2015-12-30 | 三穗县回春堂中医诊所 | Medicine for treating liver cirrhosis and preparation method thereof |
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