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CN1279899C - 含支链氨基酸颗粒的生产方法 - Google Patents

含支链氨基酸颗粒的生产方法 Download PDF

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Publication number
CN1279899C
CN1279899C CNB038027461A CN03802746A CN1279899C CN 1279899 C CN1279899 C CN 1279899C CN B038027461 A CNB038027461 A CN B038027461A CN 03802746 A CN03802746 A CN 03802746A CN 1279899 C CN1279899 C CN 1279899C
Authority
CN
China
Prior art keywords
acid
chain amino
branched
production method
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB038027461A
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English (en)
Chinese (zh)
Other versions
CN1658862A (zh
Inventor
坂井英俊
井田光泰
牧野千里
河野奉哲
矢吹昭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19191919&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1279899(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of CN1658862A publication Critical patent/CN1658862A/zh
Application granted granted Critical
Publication of CN1279899C publication Critical patent/CN1279899C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CNB038027461A 2002-01-24 2003-01-23 含支链氨基酸颗粒的生产方法 Expired - Lifetime CN1279899C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002015003A JP3368898B1 (ja) 2002-01-24 2002-01-24 分岐鎖アミノ酸含有顆粒の製造方法
JP15003/2002 2002-01-24

Publications (2)

Publication Number Publication Date
CN1658862A CN1658862A (zh) 2005-08-24
CN1279899C true CN1279899C (zh) 2006-10-18

Family

ID=19191919

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB038027461A Expired - Lifetime CN1279899C (zh) 2002-01-24 2003-01-23 含支链氨基酸颗粒的生产方法

Country Status (6)

Country Link
US (1) US7138142B2 (ja)
EP (1) EP1475089A4 (ja)
JP (1) JP3368898B1 (ja)
KR (2) KR100595962B1 (ja)
CN (1) CN1279899C (ja)
WO (1) WO2003061646A1 (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI503128B (zh) 2007-07-31 2015-10-11 Ajinomoto Kk A granule preparation containing an amino acid with excellent taste
WO2009028649A1 (ja) * 2007-08-31 2009-03-05 Ajinomoto Co., Inc. アミノ酸高含量固形製剤の低容量化製法
EP2351562A4 (en) * 2008-10-27 2012-09-05 Ajinomoto Kk SOLID SOLUTION OF VALIN, ISOLEUCIN AND LEUCIN AND MANUFACTURING PROCESS THEREFOR
JP5515943B2 (ja) * 2009-10-02 2014-06-11 味の素株式会社 分岐鎖アミノ酸を含有する顆粒、およびその製造方法
CN102908337B (zh) 2012-10-12 2014-03-05 大连医诺生物有限公司 微囊化氨基酸组合物及其制备方法
CN102960546A (zh) * 2012-12-03 2013-03-13 华中药业股份有限公司 一种复方氨基酸颗粒及其制备方法
JP6384068B2 (ja) * 2013-03-21 2018-09-05 味の素株式会社 アミノ酸含有顆粒及びその製造方法
CN103330098A (zh) * 2013-07-26 2013-10-02 湖南农业大学 一种额外添加支链氨基酸的棉铃虫幼虫半纯人工饲料及其配制方法
CN103536585B (zh) * 2013-10-24 2016-01-20 江苏神华药业有限公司 一种挤压法生产速溶支链氨基酸的方法
WO2015193485A1 (en) * 2014-06-20 2015-12-23 Hermes Arzneimittel Gmbh Taste-masked oral pharmaceutical composition
CN104906051A (zh) * 2015-07-01 2015-09-16 深圳劲创生物技术有限公司 一种营养颗粒及其制备方法
CN105249133B (zh) * 2015-10-27 2017-11-17 江苏金维氨生物工程有限公司 一种支链氨基酸添加剂
WO2017183628A1 (ja) * 2016-04-19 2017-10-26 味の素株式会社 造粒物およびその製造方法
CN106420629B (zh) * 2016-10-28 2019-10-11 广州中大南沙科技创新产业园有限公司 支链氨基酸制剂及其制备方法和应用
CN112680315A (zh) * 2020-12-28 2021-04-20 江苏澳创生物科技有限公司 一种支链氨基酸共线生产系统的使用方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3764703A (en) * 1969-11-07 1973-10-09 Astra Ab Amino acid mixture for use in treatment of uremic conditions
JPS58126767A (ja) * 1982-01-22 1983-07-28 Ajinomoto Co Inc 肝臓病患者用栄養組成物
IT1177384B (it) * 1984-12-12 1987-08-26 Boeehringer Biochemia Robin Sp Prodotti dietetici granulari a base di amminoacidi e procedimento per la loro preparazione
JPH0322366A (ja) 1989-06-20 1991-01-30 Ricoh Co Ltd 二次電池
JP2534139B2 (ja) 1989-10-09 1996-09-11 株式会社大塚製薬工場 腎不全用経口アミノ酸製剤
JP2906545B2 (ja) 1990-03-08 1999-06-21 株式会社安川電機 活線絶縁診断装置用光検出プローブの製造方法
US5635198A (en) * 1991-03-25 1997-06-03 Showa Denko K.K. Granular agent for ruminants and process for producing the same
JP3259734B2 (ja) 1992-01-20 2002-02-25 セイコーエプソン株式会社 音声認識装置
JPH0725838A (ja) * 1993-05-13 1995-01-27 Yotsuba Yuka Kk 疲労の予防または回復のための経口投与剤
JP3259463B2 (ja) 1993-09-01 2002-02-25 三菱電機株式会社 光学式情報記録再生装置
US5635210A (en) 1994-02-03 1997-06-03 The Board Of Regents Of The University Of Oklahoma Method of making a rapidly dissolving tablet
JP3617102B2 (ja) 1995-01-27 2005-02-02 味の素株式会社 ヒト筋肉疲労の早期回復効果を有するアミノ酸栄養組成物
AU706285B2 (en) * 1995-05-16 1999-06-10 Ajinomoto Co., Inc. Feed additive
CA2240810A1 (en) 1995-12-28 1997-07-10 Ajinomoto Co., Inc. Composite salt of phosphoric and amino acids with polyvalent metals and feed additive composition for ruminants
EP1116485A3 (de) * 2000-01-10 2002-01-16 Gerhard Dr. Gergely Instant-Granulat und Verfahren zu seiner Herstellung
JP3419729B2 (ja) 2000-03-16 2003-06-23 株式会社ファンケル 錠剤およびその製造方法
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
JP3211824B1 (ja) 2000-10-26 2001-09-25 味の素株式会社 分岐鎖アミノ酸含有医薬用顆粒製剤とその製造方法
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
JP3259731B1 (ja) * 2000-12-06 2002-02-25 味の素株式会社 分岐鎖アミノ酸を含有する医薬用顆粒製剤

Also Published As

Publication number Publication date
JP2003212768A (ja) 2003-07-30
WO2003061646A1 (en) 2003-07-31
KR100926895B1 (ko) 2009-11-17
EP1475089A4 (en) 2008-08-20
JP3368898B1 (ja) 2003-01-20
KR20040079950A (ko) 2004-09-16
KR100595962B1 (ko) 2006-07-06
US7138142B2 (en) 2006-11-21
EP1475089A1 (en) 2004-11-10
KR20050095905A (ko) 2005-10-04
US20050003015A1 (en) 2005-01-06
CN1658862A (zh) 2005-08-24

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