CN113952636B

CN113952636B - Radiation therapy system and safety interlocking control method thereof

Info

Publication number: CN113952636B
Application number: CN202010701469.3A
Authority: CN
Inventors: 黄永银; 陈韦霖
Original assignee: China Boron Xiamen Medical Equipment Co ltd
Current assignee: China Boron Xiamen Medical Equipment Co ltd
Priority date: 2020-07-20
Filing date: 2020-07-20
Publication date: 2023-08-08
Anticipated expiration: 2040-07-20
Also published as: CN113952636A; TW202204006A; TWI810611B

Abstract

The invention provides a radiation therapy system and a safety interlocking control method thereof, which can improve the safety of the radiation therapy system. The radiation therapy system includes a system control module, a beam generating device and an irradiation room, the beam generating device includes a charged particle beam generating device and a neutron beam generating part, the charged particle beam generated by the charged particle beam generating device and the neutron beam generating part act to generate therapeutic neutron beams to irradiate into the irradiation room, the control method includes: the beam control module judges whether the safety problem exists according to the received operation data of the charged particle beam generating device or the received operation data of the radiotherapy system, and the beam control module or the system control module controls whether the charged particle beam generating device generates a charged particle beam or acts with the neutron beam generating part through the beam control module.

Description

Radiation therapy system and safety interlocking control method thereof

Technical Field

The invention relates to the technical field of radiotherapy, in particular to a radiotherapy system and a safety interlocking control method thereof.

Background

The existing radiotherapy facilities comprise proton treatment facilities, carbon ion treatment facilities, boron neutron treatment facilities and the like, and most of the existing radiotherapy facilities utilize a shielding door of an irradiation room or a radiation monitoring component to construct a safety interlocking mechanism, namely if the shielding door of the irradiation room for treatment is not closed or the radiation monitoring value is out of limit, a beam generating device for treatment is automatically stopped immediately so as to ensure personnel safety. Although this design may provide some protection, there are still some serious drawbacks. For example, the factors involved in the safety interlock are relatively single, however, in reality the state of the beam generating device (e.g., accelerator assist device, target) and the like may also affect the treatment process, if these devices or components are abnormal during the treatment process, the treatment result may be directly affected, or injury may be caused to personnel and devices. Meanwhile, when an emergency occurs during treatment, if a patient is abnormal and needs to enter an irradiation room in time for treatment, the beam generating device needs to be turned off first and then the door is opened for treatment, and the beam generating device enters the irradiation room before being completely turned off, so that event treatment personnel are exposed to radiation; in addition, shutting down the beam generating device requires time, delays handling of the emergency situation, and forced shutting down of the beam generating device can also adversely affect the useful life of these treatment facilities.

Disclosure of Invention

In view of the above, the embodiment of the invention provides a radiation therapy system and a safety interlock control method thereof, which can improve the safety of the radiation therapy system.

According to a first aspect of an embodiment of the invention, there is provided a radiation therapy system comprising: an irradiation chamber; a beam generating device including a charged particle beam generating device and a neutron beam generating section, the charged particle beam generated by the charged particle beam generating device and the neutron beam generating section acting to generate a therapeutic neutron beam to irradiate into the irradiation chamber; the beam control module can control the charged particle beam generating device to generate a charged particle beam and receive operation data of the charged particle beam generating device; a system control module capable of controlling the charged particle beam generating device to generate a charged particle beam by the beam control module and receiving operational data of the radiation therapy system, the operational data of the radiation therapy system including operational data of the charged particle beam generating device; the beam control module judges whether the safety problem exists according to the received operation data of the charged particle beam generating device or whether the safety problem exists according to the received operation data of the radiotherapy system.

In one embodiment of the invention, a charged particle beam generating device comprises a charged particle beam generating section and a beam transmitting section, the beam transmitting section comprising a beam direction switching assembly, the charged particle beam generating section generating a charged particle beam and selectively acting with a neutron beam generating section by the beam direction switching assembly, operational data of the charged particle beam generating device comprising operational data of the charged particle beam generating section or operational data of the beam transmitting section, the operational data of the beam transmitting section comprising operational data of the beam direction switching assembly. Further, the operational data of the beam direction switching assembly may be state data of the beam direction switching assembly.

In one embodiment of the invention, the charged particle beam generating portion comprises an ion source, an accelerator and an accelerator auxiliary device, and the operational data of the charged particle beam generating portion comprises operational data of the ion source or operational data of the accelerator auxiliary device or total fault signal data of the ion source, the accelerator and the accelerator auxiliary device. Further, the ion source may include a gas supply device, an ionization device and a water cooling device, and the operation data of the ion source may be gas supply pressure, current and voltage of the ionization device, particle intensity of an ion source outlet, cooling water temperature, water flow and water pressure of the water cooling device; the accelerator can comprise pre-acceleration equipment, a front vacuum chamber, a rear vacuum chamber and high-energy acceleration equipment, wherein the pre-acceleration equipment and the high-energy acceleration equipment comprise an acceleration pipeline, a valve and an electromagnet, and the operation data of the accelerator can be the beam intensity and the insulating gas pressure in the acceleration pipeline, the current of the electromagnet and the vacuum degree of the front vacuum chamber and the rear vacuum chamber; the accelerator auxiliary equipment may include a water cooling device for providing accelerator cooling water, an air pressure device for providing compressed air, an air supply device for providing insulating gas, and a vacuum pump for providing a vacuum environment, and the operation data of the accelerator auxiliary equipment may be air pressure of the air pressure device, cooling water temperature of the water cooling device, water flow rate and water pressure, and insulating gas pressure of the air supply device.

In one embodiment of the invention, the radiation therapy system further comprises a charged particle beam generating chamber housing the charged particle beam generating section, a beam transport chamber housing the beam direction switching assembly, a shielding door of the charged particle beam generating chamber, and a shielding door of the beam transport chamber, and the operational data of the radiation therapy system further comprises operational data of the shielding door of the charged particle beam generating chamber or operational data of the shielding door of the beam transport chamber. Further, the operation data of the shielding door may be state data of opening or closing the shielding door or signal data of opening.

In one embodiment of the invention, the charged particle beam generating device comprises a charged particle beam monitoring assembly, and the operational data of the charged particle beam generating device comprises operational data of the charged particle beam monitoring assembly. Further, the operational data of the charged particle beam monitoring assembly may be a monitored value of the charged particle beam monitoring assembly.

In one embodiment of the invention, the beam generating device further comprises a neutron beam monitoring assembly, and the operational data of the radiation therapy system further comprises operational data of the neutron beam monitoring assembly or operational data of the neutron beam generating section. Further, the operation data of the neutron beam monitoring assembly may be a monitoring value of the neutron beam monitoring assembly; the neutron beam generating part can comprise a target, a beam shaping body and a collimator, and the operation data of the neutron beam generating part can be service life data of the target, temperature data of the target, model data of the collimator or inconsistent signal data of the collimator.

In one embodiment of the invention, the radiation therapy system further comprises a shielded gate of the irradiation chamber and a radiation monitoring assembly disposed in the irradiation chamber, and the operational data of the radiation therapy system further comprises operational data of the shielded gate of the irradiation chamber or operational data of the radiation monitoring assembly. Further, the operation data of the shielding door may be state data or signal data of opening or closing of the shielding door, and the operation data of the radiation monitoring component may be a monitoring value of the radiation monitoring component.

In one embodiment of the invention, the radiation therapy system further comprises a patient status monitoring component or an activity monitoring component, and the operational data of the radiation therapy system further comprises operational data of the patient status monitoring component or operational data of the activity monitoring component. Further, the operation data of the patient state monitoring component may be a monitoring value of the patient state monitoring component or signal data of patient abnormality, and the operation data of the activity monitoring component may be a monitoring value of the activity monitoring component or signal data of activity abnormality.

In one embodiment of the invention, the radiation therapy system further comprises a treatment planning module, and the operational data of the radiation therapy system further comprises treatment planning data retrieved by the system control module from the treatment planning module.

In one embodiment of the invention, signals of the irradiation chamber status may also be provided, and the radiation therapy system operational data may also include signal data of the irradiation chamber status.

According to a second aspect of the embodiments of the present invention, there is provided a safety interlock control method of the above radiotherapy system, the control method comprising: before the beam generating device generates a therapeutic neutron beam to start to irradiate into the irradiation chamber, the beam control module prohibits the charged particle beam generating device from generating the charged particle beam by the beam control module when the beam control module determines that the irradiation of the irradiation chamber to be started has a safety problem according to the received operation data of the charged particle beam generating device or the received operation data of the radiotherapy system; or when the beam control module determines that there is a safety problem in the irradiation of the irradiation chamber according to the received operation data of the charged particle beam generating device or the received operation data of the radiotherapy system when the beam generating device generates a therapeutic neutron beam and irradiates the irradiation chamber, the beam control module or the system control module controls the charged particle beam generating device to stop generating the charged particle beam or controls the charged particle beam generated by the charged particle beam generating device to stop acting on the neutron beam generating part through the beam control module.

According to the technical scheme provided by the embodiment of the invention, the charged particle beam generating device is a source for generating a neutron beam for treatment, and the beam applied to a patient is directly caused to have a problem when an abnormality occurs, so that the treatment effect is directly affected or the personnel and equipment are damaged, and the charged particle beam generating device is extremely important as a safety interlocking factor.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is apparent that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

Fig. 1 is a block diagram of a radiation therapy system according to an embodiment of the present invention.

Fig. 2 is a schematic diagram of a radiation therapy system for treating a patient according to an embodiment of the present invention.

FIG. 3 is a flow chart illustrating a method for controlling the safety interlock of a radiation therapy system according to an embodiment of the present invention.

Fig. 4 is a block diagram of a radiation therapy system provided in accordance with another embodiment of the present invention.

Fig. 5 is a schematic diagram illustrating a radiation therapy system according to another embodiment of the present invention.

FIG. 6 is a flow chart of a method for controlling a safety interlock of a radiation therapy system according to another embodiment of the present invention.

FIG. 7 is a block diagram of a safety interlock control system of a radiation therapy system according to one embodiment of the present invention.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

Fig. 1 is a block diagram of a radiation therapy system according to an embodiment of the present invention. As shown in fig. 1, the radiation therapy system 100 includes a first irradiation chamber 101, a beam generating device 10, a beam control module 20, and a system control module 30. The beam generating device 10 may generate a therapeutic beam and emit the beam to the first irradiation chamber 101, the first irradiation chamber 101 may interact with the system control module 30, the beam generating device 10 may interact with the beam control module 20 or the system control module 30, and the system control module 30 may interact with the beam control module 20. The system control module 30 may transmit data input by an operator such as a physician or received, stored data of the beam generating device 10, the first irradiation chamber 101, etc. to the beam control module 20 to control the beam generating device 10 to emit a beam to the first irradiation chamber 101.

As shown in fig. 2, in an embodiment of the present invention, the beam generating device 10 is a neutron beam generating device, and includes a charged particle beam generating section 11, a beam transmitting section 12, and a first neutron beam generating section 13. The beam control module 20 or the system control module 30 can control the charged particle beam generator 11 to generate the charged particle beam P by the beam control module 20 and can control the beam transmission unit 12 to transmit the charged particle beam P generated by the charged particle beam generator 11 to the first neutron beam generator 13, and the beam transmission unit 12 is configured by a transmission tube. The first neutron generator 13 corresponds to the first irradiation chamber 101 (not shown in the figure), and the charged particle beam P acts on the first neutron beam generator 13 to generate a therapeutic neutron beam N and irradiates the patient 200 on the treatment table 40 provided in the first irradiation chamber 101, thereby performing irradiation treatment on the patient 200, for example, performing boron neutron capture treatment on tumor cells M in the patient 200. It should be appreciated that the generated neutron beam may also be used for other purposes, as the invention is not particularly limited in this regard; the beam generator 10 may be any other radiation generator, and the charged particle beam generator 11 and the neutron beam generator 13 may be replaced or omitted accordingly, for example, the charged particle beam P generated by the charged particle beam generator 11 may be directly transferred to the first irradiation chamber 101 to be irradiated with the charged particle beam P, and the charged particle beam P may be used for treatment, other purposes, or the like.

The beam control module 20 or the system control module 30 may receive the operation data of the radiation therapy system 100 and determine whether there is a safety problem according to the operation data, and in particular, the beam control module 20 may receive the operation data of the beam generating device 10 (the charged particle beam generating part 11 or the beam transmitting part 12), and the system control module 30 may receive the operation data of the beam generating device 10 or the first irradiation chamber 101. As shown in FIG. 3, the safety interlock control method according to an embodiment of the present invention is as follows:

s301: before the beam generator 10 emits the beam to the first irradiation chamber 101 (e.g., before the therapeutic neutron beam N is generated and irradiated into the first irradiation chamber 101), the beam control module 20 or the system control module 30 determines whether or not the irradiation of the first irradiation chamber 101 to be started has a safety problem based on the received operation data of the radiation therapy system 100.

S302: according to the determination result of S301, when it is determined that there is a safety problem in the irradiation of the first irradiation chamber 101 that is to be started, a safety interlock mechanism is triggered, and the beam control module 20 or the system control module 30 may control the beam generating device 10 to prohibit the emission of the beam to the first irradiation chamber 101 through the beam control module 20, prohibit the first irradiation chamber 101 from starting the irradiation treatment, for example, prohibit the charged particle beam generating section 11 from generating the charged particle beam P.

S303: when it is determined that there is no safety problem in the irradiation of the first irradiation room 101 to be started according to the determination result of S301, the beam control module 20 or the system control module 30 controls the beam generating device 10 to emit the beam to the first irradiation room 101 through the beam control module 20, and starts the irradiation treatment of the first irradiation room 101, for example, controls the charged particle beam generating section 11 to generate the charged particle beam P and acts with the first neutron beam generating section 13 to generate the neutron beam N for the treatment required for the patient 200 to be currently irradiated in the first irradiation room 101 to irradiate into the first irradiation room 101.

S304: when the beam generator 10 of S303 emits the beam to the first irradiation chamber 101 (e.g., when the therapeutic neutron beam N is generated and starts to irradiate into the first irradiation chamber 101), the beam control module 20 or the system control module 30 determines whether or not there is a safety problem in the irradiation of the first irradiation chamber 101 based on the received operation data of the radiation therapy system 100.

S305: when it is determined that there is no safety problem in the irradiation of the first irradiation chamber 101 according to the determination result of S304, the irradiation is continued on the first irradiation chamber 101, that is, the beam generating device 10 is controlled to continuously emit the beam to the first irradiation chamber 101.

S306: when it is determined that there is a safety problem in the irradiation of the first irradiation chamber 101 according to the determination result of S304, the safety interlock mechanism is triggered, and the beam control module 20 or the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, so as to end the irradiation treatment of the first irradiation chamber 101, for example, control the charged particle beam generating part 11 to stop generating the charged particle beam P.

It should be understood that control of the safety interlock may also be performed only at or before irradiation.

In an embodiment of the present invention, as shown in fig. 4, the charged particle beam generating section 11 includes an ion source 111, an accelerator 112, and an accelerator auxiliary device 113, to which the present invention is not limited in particular. The ion source 111 is used to generate charged particles, e.gH ^- Protons, deuterons, etc.; it should be appreciated that the ion source 111 may be a sputter ion source, a high frequency ion source, a dual plasma ion source, a penning ion source, etc., and the type of ion source is not particularly limited in the present invention. In one embodiment, the ion source 111 includes a gas supply device, an ionization device, a water cooling device, etc., which is not particularly limited in the present invention.

The accelerator 112 accelerates charged particles generated by the ion source 111 to obtain a charged particle beam P of a desired energy or the like, such as a proton beam; it should be appreciated that the accelerator 112 may be a linear accelerator, a cyclotron, a synchrotron, a synchrocyclotron, etc., and the type of accelerator is not particularly limited by the present invention. In one embodiment, the accelerator 112 includes a pre-acceleration device, a front-to-back vacuum chamber, a high-energy acceleration device, etc., which are constructed of acceleration pipes, valves, electromagnets, etc., which are not particularly limited in this disclosure.

The accelerator auxiliary device 113 may include any auxiliary device for providing a precondition for the operation of the accelerator 112. In one embodiment, the accelerator auxiliary device 113 includes a water cooling device for supplying accelerator cooling water, an air compression device for supplying compressed air, an air supply device for supplying insulating gas, a vacuum pump for supplying a vacuum environment, and the like, which is not particularly limited in the present invention.

The ion source 111, the accelerator 112 and the accelerator assist device 113 may be respectively connected to the beam control module 20 or the system control module 30 and data-interacted so that the beam control module 20 or the system control module 30 may determine whether there is a safety problem with the irradiation of the first irradiation chamber 101, i.e. the operation data of the radiation therapy system 100 includes the operation data of the charged particle beam generating section 11, and the operation data of the charged particle beam generating section 11 further includes the operation data of the ion source 111, the accelerator 112 and the accelerator assist device 113. For example, operational data of the ion source 111, such as gas supply pressure, current and voltage of the ionization device, particle intensity at the ion source outlet, cooling water temperature of the water cooling device, water flow rate, water pressure, etc., may be transmitted to the beam control module 20 or the system control module 30; operational data of the accelerator 112, such as beam intensity and insulating gas pressure in the acceleration duct, current of the electromagnet, vacuum degree of the front and rear vacuum chambers, etc., may also be transmitted to the beam control module 20 or the system control module 30; the operation data of the accelerator auxiliary equipment 113, such as the air pressure of the air-pressure equipment, the cooling water temperature of the water-cooling equipment, the water flow rate and water pressure, the insulating gas pressure of the air supply equipment, etc., may also be transmitted to the beam control module 20 or the system control module 30; the total fault signal of the ion source 111, the accelerator 112 and the accelerator auxiliary device 113 may also be transmitted to the beam control module 20; the content of the data interaction is not particularly limited by the present invention.

The beam control module 20 or the system control module 30 determines that a safety problem exists and performs safety interlocking according to the received operation data of the radiation therapy system 100, including when the beam control module 20 or the system control module 30 determines that an abnormality or an operation data overrun exists according to the received operation data of the charged particle beam generating section 11 before the beam generating apparatus 10 emits the beam to the first irradiation chamber 101 or when the beam is emitted to the first irradiation chamber 101, that is, the safety interlocking mechanism is triggered.

Before the beam generating device 10 emits the beam to the first irradiation chamber 101, when the beam control module 20 or the system control module 30 judges abnormality or operation data overrun from the received operation data of the charged particle beam generating section 11, it includes: the operation data of the ion source 111, such as that the air supply pressure exceeds a preset range, or that the current or voltage of the ionization device exceeds a preset range, or that the particle intensity of the ion source outlet exceeds a preset range, or that the cooling water temperature or water flow or water pressure of the water cooling device exceeds a preset range, etc.; or the operation data of the accelerator 112, such as that the beam intensity or the insulating gas pressure in the accelerating pipeline exceeds a preset range, or that the current of the electromagnet exceeds a preset range, or that the vacuum degree of the front vacuum chamber and the rear vacuum chamber exceeds a preset range, etc.; or the operation data of the accelerator auxiliary device 113, such as that the air pressure of the air-pressure device exceeds a preset range, or that the cooling water temperature or water flow or water pressure of the water-cooling device exceeds a preset range, or that the insulating gas pressure of the air supply device exceeds a preset range, determines that the irradiation of the first irradiation chamber 101 to be started has a safety problem, namely, a safety interlocking mechanism is triggered, and the beam control module 20 or the system control module 30 can control the beam generating device 10 to prohibit the emission beam to the first irradiation chamber 101 through the beam control module 20, so that the irradiation treatment of the first irradiation chamber 101 is prohibited; in an embodiment, a total fault signal of the ion source 111, the accelerator 112 and the accelerator auxiliary device 113 may be further set, when the beam control module 20 receives the total fault signal of the ion source 111, the accelerator 112 and the accelerator auxiliary device 113, the fault signal indicates that the fault is a major fault, it is determined that the irradiation of the first irradiation chamber 101 to be started has a safety problem, that is, a safety interlock mechanism is triggered, and the beam control module 20 may prohibit the charged particle beam generating part 11 from generating the charged particle beam P after receiving the fault signal, and prohibit the first irradiation chamber 101 from starting the irradiation treatment.

When the beam control module 20 or the system control module 30 judges that abnormality or operation data is exceeded based on the received operation data of the charged particle beam generating section 11 when the beam generating apparatus 10 emits the beam to the first irradiation chamber 101, it includes: the operation data of the ion source 111, such as that the air supply pressure exceeds a preset range, or that the current or voltage of the ionization device exceeds a preset range, or that the particle intensity of the ion source outlet exceeds a preset range, or that the cooling water temperature or water flow or water pressure of the water cooling device exceeds a preset range, etc.; or the operation data of the accelerator 112, such as that the beam intensity or the insulating gas pressure in the accelerating pipeline exceeds a preset range, or that the current of the electromagnet exceeds a preset range, or that the vacuum degree of the front vacuum chamber and the rear vacuum chamber exceeds a preset range, etc.; or the operation data of the accelerator auxiliary device 113, such as that the air pressure of the air compression device exceeds a preset range, or that the cooling water temperature or water flow or water pressure of the water cooling device exceeds a preset range, or that the insulating gas pressure of the air supply device exceeds a preset range, determines that the irradiation of the first irradiation chamber 101 has a safety problem, triggers a safety interlocking mechanism, and the beam control module 20 or the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, so as to end the irradiation treatment of the first irradiation chamber 101; when the beam control module 20 receives the total fault signal of the ion source 111, the accelerator 112 and the accelerator auxiliary device 113, which is generally a serious fault, it is determined that the irradiation of the first irradiation chamber 101 has a safety problem, that is, a safety interlock mechanism is triggered, after the beam control module 20 receives the fault signal, the beam control module 20 can control the charged particle beam generating part 11 to stop generating the charged particle beam P, for example, the ion source 111 is turned off or the accelerator 112 is turned off, so as to end the irradiation treatment of the first irradiation chamber 101.

Since the charged particle beam generating section is a source for generating a therapeutic neutron beam, and the accelerator is an important device for generating a desired charged particle beam, the occurrence of an abnormality directly causes a problem in the beam applied to a patient, thereby directly affecting the therapeutic effect or causing damage to personnel and devices, and thus is extremely important as a safety interlock factor.

In another embodiment of the present invention, as shown in connection with fig. 5, the radiation therapy system 100 further includes a second irradiation chamber 101', the beam generating apparatus 10 further includes a second neutron beam generating section 13' corresponding to the second irradiation chamber 101', the beam transmitting section 12 includes a beam direction switching element 121, and the beam transmitting section 12 selectively transmits the charged particle beam P generated by the charged particle beam generating section 11 to the first neutron beam generating section 13 or the second neutron beam generating section 13' through the beam direction switching element 121, thereby emitting the beam into the first irradiation chamber 101 or the second irradiation chamber 101 '. It should be understood that the neutron beam N irradiated into the second irradiation chamber 101' may be used for treatment of neutron beam N irradiation of another patient on the treatment couch 40' in the second irradiation chamber 101', may also be used for sample detection, etc., which is not limited in the present invention; in the case where the beam generator 10 is another radiation generator, the second neutron beam generator 13 'may be replaced with the beam generator, and the beam transmitter 12 may selectively emit the beam into the first irradiation chamber 101 or the second irradiation chamber 101' through the beam direction switching unit 121.

It should be appreciated that other configurations of the beam generating apparatus 10 are possible. If the third irradiation chamber exists, the third neutron beam generating part can be added to correspond to the third irradiation chamber, and the number of the neutron beam generating parts corresponds to the number of the irradiation chambers; the system cost can be effectively reduced by providing one charged particle beam generating unit to transmit to each neutron beam generating unit, and it is understood that the beam generating apparatus may include a plurality of charged particle beam generating units to transmit to each neutron beam generating unit, and a plurality of neutron beams can be simultaneously generated and irradiated in a plurality of irradiation chambers.

In an embodiment of the present invention, the beam direction switching unit 121 includes a deflection magnet (not shown) for deflecting the charged particle beam P in a direction, and if the deflection magnet corresponding to the first irradiation chamber 101 is turned on, the beam is introduced into the first irradiation chamber 101, which is not particularly limited in the present invention. The beam transmission unit 12 may further include a beam adjustment unit (not shown) for the charged particle beam P, the beam adjustment unit including a horizontal diverter and a horizontal-vertical diverter for adjusting the axis of the charged particle beam P, a quadrupole electromagnet for suppressing divergence of the charged particle beam P, a four-way cutter for shaping the charged particle beam P, and the like. The beam transfer unit 12 may further include a charged particle beam scanning unit (not shown) for scanning the charged particle beam P, and for performing irradiation control of the charged particle beam P with respect to the neutron beam generating units 13 and 13', such as controlling the irradiation position of the charged particle beam P with respect to the target 131 (described below), as necessary.

The beam delivery portion 12 may be coupled to and data-interacted with the system control module 30 or the beam control module 20, respectively, to facilitate the beam control module 20 or the system control module 30 determining whether the irradiation of the first irradiation chamber 101 is safe, i.e., the operational data of the radiation therapy system 100 includes operational data of the beam delivery portion 12. For example, the vacuum degree of the transmission tube, the voltage of the magnet, the temperature of the magnet, the state (e.g., on state) data of the beam direction switching assembly 121, etc. may be transmitted to the system control module 30 or the beam control module 20, and the content of the data interaction is not particularly limited in the present invention.

The beam control module 20 or the system control module 30 determines that a safety problem exists and performs safety interlocking according to the received operation data of the radiation therapy system 100, including when the beam control module 20 or the system control module 30 determines that an abnormality or operation data overrun according to the received operation data of the beam transmitting portion 12 before the beam generating device 10 transmits the beam to the first irradiation chamber 101 or when the beam is transmitted to the first irradiation chamber 101, determining that the safety problem exists, that is, triggering the safety interlocking mechanism.

Before the beam generating device 10 emits the beam to the first irradiation chamber 101, when the beam control module 20 or the system control module 30 determines that the abnormality or the operation data is exceeded according to the received operation data of the beam transmission part 12, for example, the vacuum degree of the transmission tube exceeds the preset range or the voltage of the magnet exceeds the preset range or the temperature of the magnet exceeds the preset range or the state data of the beam direction switching component 121 indicates that the beam direction switching component 121 does not conduct the beam to the first irradiation chamber 101, it is determined that the irradiation of the first irradiation chamber 101 to be started has a safety problem, that is, a safety interlocking mechanism is triggered, the beam control module 20 or the system control module 30 can control the beam generating device 10 to prohibit the emission of the beam to the first irradiation chamber 101 through the beam control module 20, and prohibit the first irradiation chamber 101 from starting the irradiation treatment.

When the beam generating device 10 emits the beam to the first irradiation chamber 101, when the beam control module 20 or the system control module 30 determines that the abnormality or the operation data is over-limit according to the received operation data of the beam transmission part 12, for example, the vacuum degree of the transmission tube exceeds the preset range or the voltage of the magnet exceeds the preset range or the temperature of the magnet exceeds the preset range or the state data of the beam direction switching component 121 indicates that the beam direction switching component 121 does not conduct the beam to the first irradiation chamber 101, it is determined that the irradiation of the first irradiation chamber 101 has a safety problem, that is, a safety interlocking mechanism is triggered, the beam control module 20 or the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, and the irradiation treatment of the first irradiation chamber 101 is ended.

The beam transmission unit transmits a beam to an irradiation room requiring treatment, for example, a charged particle beam to a neutron beam generation unit corresponding to the irradiation room requiring treatment, thereby generating a therapeutic neutron beam in the irradiation room, and if the beam transmission unit is abnormal, a beam may be generated in another irradiation room or a correct beam may not be generated in the irradiation room requiring treatment, and serious safety accidents may occur or the treatment effect may be affected.

In an embodiment of the present invention, as shown in fig. 2, the first neutron beam generating section 13 may include a target 131, a beam shaping body 132, and a collimator 133, which is not particularly limited in the present invention. For example, the charged particle beam P generated by the accelerator 112 irradiates the target 131 through the beam transmitting unit 11 and reacts with the target 131 to generate neutrons, and the generated neutrons sequentially pass through the beam shaping body 132 and the collimator 133 to form a neutron beam N and irradiate the neutron beam N onto the patient 200 on the treatment table 40 provided in the first irradiation chamber 101. The target 131 can be a metal target, such as a lithium target or a beryllium target, etc., which is in contact with the proton line ⁹ Be(p,n) ⁹ B or ⁷ Li(p,n) ⁷ Be nuclear reaction to generate neutrons, the material of the target 131 of the present invention is not particularly limited. The number of collimators 133 may be different, and the size, shape, etc. may be different, so as to adapt to different patients to be irradiated, and in an embodiment, an identification mechanism is provided on the collimators 133, and the system control module 30 may automatically identify and obtain model data of the collimators 133, or an operator such as a doctor manually inputs the model data of the collimators 133 according to the identification mechanism and transmits the model data to the system control module 30, or an operator such as a doctor determines inconsistency according to the identification mechanism and sends a signal of the inconsistency of the collimators to the system control module 30. The specific construction of the target 131, beam shaper 132 and collimator 133 is not described in detail here. The second neutron beam generating section 13' may have the same configuration as the first neutron beam generating section 13, which is not particularly limited in the present invention.

The first neutron beam generating section 13 may be connected to and data-interacted with the system control module 30 so that the system control module 30 can determine whether there is a safety issue with the irradiation of the first irradiation chamber 101, i.e., the operational data of the radiation therapy system 100 includes the operational data of the first neutron beam generating section 13. For example, the service life of the target 131, the temperature of the target 131, the model data of the collimator 133, or the signal data of the inconsistent collimator may be transmitted to the system control module 30, and the content of the data interaction is not particularly limited in the present invention.

The beam control module 20 or the system control module 30 determines that a safety problem exists and performs safety interlocking according to the received operation data of the radiation therapy system 100, including when the system control module 30 determines that an abnormality or an operation data overrun exists according to the received operation data of the first neutron beam generating section 13 before the beam generating device 10 emits the beam to the first irradiation chamber 101 or when the beam is emitted to the first irradiation chamber 101, the safety interlock mechanism is triggered.

Before the beam generating device 10 emits the beam to the first irradiation chamber 101, when the system control module 30 determines that the abnormality or the operation data is over-limit according to the received operation data of the first neutron beam generating section 13, if the service life of the target 131 is insufficient to complete the next treatment or the temperature of the target 131 exceeds the preset range or the model data of the collimator 133 shows signal data inconsistent with the patient to be irradiated or inconsistent with the collimator, it is determined that the irradiation of the first irradiation chamber 101 to be started has a safety problem, that is, a safety interlock mechanism is triggered, and the system control module 30 can control the beam generating device 10 to prohibit emission of the beam to the first irradiation chamber 101 and prohibit the first irradiation chamber 101 from starting irradiation treatment through the beam control module 20.

When the beam generating device 10 emits the beam to the first irradiation chamber 101, when the system control module 30 determines that the operation data is abnormal or the operation data is over-limited according to the received operation data of the first neutron beam generating section 13, if the service life of the target 131 is over a preset range or the temperature of the target 131 is over a preset range, it is determined that the irradiation of the first irradiation chamber 101 has a safety problem, that is, a safety interlock mechanism is triggered, the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, and the irradiation treatment of the first irradiation chamber 101 is ended.

The neutron beam generating part is extremely critical to the generation of therapeutic neutron beams and the acquisition of beam quality meeting the therapeutic requirements, and the therapeutic effect is ensured by incorporating the therapeutic neutron beams into the safety interlocking factors.

In another embodiment of the present invention, as shown in fig. 4 and 5, the radiation therapy system 100 further includes a charged particle beam generating chamber 102 housing the charged particle beam generating section 11, a beam transmitting chamber 103 housing at least partially the beam transmitting section 12 (e.g., housing the beam direction switching assembly 121), a shielding door a (B) of the charged particle beam generating chamber 102, and a shielding door C of the beam transmitting chamber 103, which are not particularly limited in this regard. The status data of the opening or closing of the shielding door can be transmitted to the system control module 30, or the operator can transmit a signal of the opening of the shielding door to the system control module 30 according to the observed condition. The shielding gate a (B) of the charged particle beam generating chamber 102 and the shielding gate C of the beam transmitting chamber 103 are respectively connected to the system control module 30 and data-interacted so that the system control module 30 can determine whether the irradiation of the first irradiation chamber 101 has a safety problem, i.e. the operation data of the radiation therapy system 100 includes the operation data of the shielding gate a (B) of the charged particle beam generating chamber 102 and the shielding gate C of the beam transmitting chamber 103. For example, the state data of opening or closing the shielding door a (B) of the charged particle beam generating chamber 102 or the shielding door C of the beam transmitting chamber 103, the signal data of opening, or the like may be transmitted to the system control module 30, and the content of the data interaction is not particularly limited in the present invention. The charged particle beam generation chamber 102 is usually installed in a space of two floors, and the charged particle beam generation chamber shielding door a and the charged particle beam generation chamber shielding door B are installed on the two floors, respectively.

The beam control module 20 or the system control module 30 determines that the irradiation of the first irradiation chamber 101 is safe and safety-interlocked based on the received operation data of the radiation therapy system 100, including:

before the beam generating device 10 emits the beam to the first irradiation chamber 101, when the system control module 30 determines that the operation of the shielding door a (B) of the charged particle beam generating chamber 102 or the shielding door C of the beam transmission chamber 103 is abnormal, such as the opened state data or the opened signal data of the shielding door a, the shielding door B or the shielding door C, it is determined that the irradiation of the first irradiation chamber 101 to be started has a safety problem, that is, a safety interlock mechanism is triggered, the system control module 30 can control the beam generating device 10 to prohibit emission of the beam to the first irradiation chamber 101 and prohibit the first irradiation chamber 101 from starting irradiation treatment through the beam control module 20;

when the system control module 30 determines that the operation of the shielding door a (B) of the charged particle beam generating chamber 102 or the shielding door C of the beam transmission chamber 103 is abnormal when the beam generating device 10 emits the beam to the first irradiation chamber 101, such as the opened state data or the opened signal data of the shielding door a, the shielding door B or the shielding door C, it is determined that the irradiation of the first irradiation chamber 101 has a safety problem, that is, the safety interlock mechanism is triggered, and the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, and the irradiation treatment of the first irradiation chamber 101 is ended.

The beam generating device can generate high-energy radioactive rays when in operation, and the shielding doors of the charged particle beam generating chamber and the beam transmission chamber are closed during irradiation treatment, so that the safety of personnel is ensured, radiation pollution is avoided, and the high-energy radioactive rays are necessary to be brought into factors of safety interlocking.

In one embodiment, the beam generating apparatus 10 further includes a beam monitoring assembly 14, and the beam monitoring assembly 14 may include a charged particle beam monitoring assembly or a neutron beam monitoring assembly, as the invention is not limited in detail. As shown in fig. 4, in this embodiment, the beam monitoring assembly 14 is a charged particle beam monitoring assembly, which is disposed in the beam transmission chamber 103, such as on the inner wall of the transmission tube of the beam transmission section 12, and monitors the beam intensity by measuring the current of the charged particle beam P, etc., it should be understood that the charged particle beam intensity monitoring assembly 14 may also be disposed in the corresponding apparatus of the charged particle beam generating chamber 102, such as the ion source 111 or the accelerator 112; the voltage, energy, etc. of the charged particle beam P may also be monitored. The neutron beam monitoring assembly may be disposed at the first neutron beam generating section 13, such as by measuring radiation generated at the target 131 to monitor the neutron beam intensity, or at the neutron beam exit or within the beam shaping body. The number and arrangement positions of the beam monitoring components 14 are not particularly limited in the present invention.

The beam monitoring assembly 14 may be coupled to and data-interacted with the beam control module 20 or the system control module 30 to facilitate the beam control module 20 or the system control module 30 determining whether there is a safety issue with the irradiation of the first irradiation chamber 101, i.e., the operational data of the radiation therapy system 100 includes operational data of the beam monitoring assembly 14, and the operational data of the beam monitoring assembly 14 further includes operational data of the charged particle beam monitoring assembly and operational data of the neutron beam monitoring assembly. For example, the operation data of the charged particle beam monitoring assembly, such as the charged particle beam P current, may be transmitted to the beam control module 20 or the system control module 30, or the operation data of the neutron beam monitoring assembly, such as the neutron beam intensity or other radiation detection data of the neutron generating section, may be transmitted to the system control module 30, and the content of the data interaction is not particularly limited in the present invention.

The beam control module 20 or the system control module 30 determines that a safety problem exists and performs safety interlocking according to the received operation data of the radiation therapy system 100, including when the beam control module 20 or the system control module 30 determines that the abnormality or the operation data is out of limit according to the received operation data of the beam monitoring assembly 14 before the beam generating device 10 emits the beam to the first irradiation chamber 101 or when the beam is emitted to the first irradiation chamber 101, determining that the safety problem exists, that is, triggering the safety interlocking mechanism.

Before the beam generating device 10 emits the beam to the first irradiation chamber 101, when the beam control module 20 or the system control module 30 determines that the abnormality or the operation data is exceeded according to the received operation data of the beam monitoring component 14, the operation data including the operation data of the charged particle beam monitoring component, such as the current of the charged particle beam P, exceeds the preset range, determines that the irradiation of the first irradiation chamber 101 to be started has a safety problem, that is, triggers a safety interlock mechanism, and the beam control module 20 or the system control module 30 can control the beam generating device 10 to prohibit emission of the beam to the first irradiation chamber 101 through the beam control module 20, and prohibit the first irradiation chamber 101 from starting irradiation treatment; or when the system control module 30 determines that the abnormality or the operation data exceeds the limit according to the received operation data of the beam monitoring component 14, the operation data including the neutron beam monitoring component, such as the neutron beam intensity exceeds the preset range, determines that the irradiation of the first irradiation chamber 101 to be started has a safety problem, that is, triggers a safety interlocking mechanism, and the system control module 30 can control the beam generating device 10 to prohibit the emission beam to the first irradiation chamber 101 through the beam control module 20, so as to prohibit the first irradiation chamber 101 from starting irradiation treatment.

When the beam generating device 10 emits the beam to the first irradiation chamber 101, when the beam control module 20 or the system control module 30 determines that the abnormal or operation data exceeds the limit according to the received operation data of the beam monitoring component 14, including the monitoring value of the neutron beam monitoring component, such as the current of the charged particle beam exceeding the preset range, it is determined that the irradiation of the first irradiation chamber 101 has a safety problem, that is, a safety interlock mechanism is triggered, and the beam control module 20 or the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, so as to end the irradiation treatment of the first irradiation chamber 101; or when the system control module 30 determines that the abnormality or the operation data exceeds the limit according to the received operation data of the beam monitoring component 14, including the monitoring value of the neutron beam monitoring component, if the neutron beam intensity exceeds the preset range, it is determined that the irradiation of the first irradiation chamber 101 has a safety problem, that is, a safety interlocking mechanism is triggered, the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20, and the irradiation treatment of the first irradiation chamber 101 is ended.

The monitoring value of the beam monitoring assembly can directly judge whether the beam meets the requirement or whether the equipment is operating normally, and the beam monitoring assembly is necessary to incorporate the factors of safety interlocking.

In another embodiment of the present invention, the radiation therapy system 100 further includes a shielding door E1 of the first irradiation chamber 101, and a radiation monitoring assembly 50 disposed in the first irradiation chamber 101, wherein the radiation monitoring assembly 50 is configured to monitor doses of various radiation (such as neutrons and gamma rays) in the first irradiation chamber 101, and in one embodiment, calculate boron concentration and tumor dose by detecting transient gamma rays emitted from an irradiated portion after the irradiation of the neutron beam N. It should be appreciated that the shielding door E1 of the first irradiation chamber 101 may be one or more, such as including a primary shielding door and a secondary shielding door; the number of the radiation monitoring components 50 in the first irradiation chamber 101 may be one or more, and the number of the shielding doors E1 and the radiation monitoring components 50 is not particularly limited in the present invention. The radiation therapy system 100 also includes a patient condition monitoring assembly 60 and an activity monitoring assembly 70. The patient condition monitoring assembly 60 may monitor whether the patient is out of position, whether the patient is physically uncomfortable, the intake of boron drugs in the patient, etc., and it will be appreciated that the patient may trigger a patient abnormality signal on the patient condition monitoring assembly 60 or send a patient abnormality signal to the system control module 30 based on his or her own condition or based on an observed condition. The activity monitoring component 70 can monitor whether personnel remain in the radiation control area or the abnormal activity of the object in the irradiation room or not through image recognition, a thermal sensor, an infrared sensor, an ultrasonic sensor, a pressure sensor or a laser sensor and the like, and more than two or different types of sensing components can be adopted to ensure the reliability and the safety; it is also possible that the operator triggers an abnormal activity signal on the activity monitoring assembly 70 or sends an abnormal activity signal to the system control module 30 based on the observed situation. As shown in fig. 4, in this embodiment, the patient condition monitoring assembly 60 and the activity monitoring assembly 70 are disposed within the first irradiation chamber 101, as the invention is not limited in detail. It should be appreciated that the second illumination chamber may have the same arrangement as the first illumination chamber.

The shielding door E1 of the first irradiation chamber 101, the radiation monitoring assembly 50, the patient status monitoring assembly 60, and the activity monitoring assembly 70 may be respectively connected to and data-interacted with the system control module 30 to facilitate the system control module 30 to determine whether the irradiation of the first irradiation chamber 101 is safe, i.e., the operational data of the radiation therapy system 100 includes operational data of the shielding door E1 of the first irradiation chamber 101, operational data of the radiation monitoring assembly 50, operational data of the patient status monitoring assembly 60, and operational data of the activity monitoring assembly 70. For example, the data such as the opened or closed state data or the opened signal data of the shielding door E1 of the first irradiation chamber 101, the monitoring value of the radiation monitoring assembly 50, the monitoring value of the patient state monitoring assembly 60 or the signal of the patient abnormality, the monitoring value of the activity monitoring assembly 70 or the signal of the activity abnormality may be transmitted to the system control module 30, and the content of the data interaction is not particularly limited in the present invention.

The beam control module 20 or the system control module 30 determines that a safety problem exists and performs safety interlock according to the received operation data of the radiation therapy system 100, including determining that a safety problem exists, i.e., triggering a safety interlock mechanism, when the system control module 30 determines that an abnormality or operation data is out of limit according to the received operation data of the shielding door E1 of the first irradiation chamber 101, the operation data of the radiation monitoring assembly 50, the operation data of the patient status monitoring assembly 60, or the operation data of the activity monitoring assembly 70 before the beam generating device 10 emits a beam to the first irradiation chamber 101 or when the beam is emitted to the first irradiation chamber 101.

Before the beam generating device 10 emits the beam to the first irradiation chamber 101, when the system control module 30 determines that there is a safety problem in the irradiation of the first irradiation chamber 101 to be started, that is, a safety interlock mechanism is triggered, according to the received operation data of the shielding door E1 of the first irradiation chamber 101, the operation data of the radiation monitoring assembly 50, the operation data of the patient state monitoring assembly 60, or the operation data of the activity monitoring assembly 70, if the opened state data of the shielding door E1 of the first irradiation chamber 101 or the opened signal data of the radiation monitoring assembly 50 exceeds a preset range or the monitored value of the patient state monitoring assembly 60 exceeds the preset range or the monitored value of the patient abnormal state monitoring assembly 60 or the monitored value of the activity monitoring assembly 70 exceeds the preset range or the abnormal activity signal of the activity monitoring assembly 70, the system control module 30 can control the beam generating device 10 to prohibit the emission of the beam to the first irradiation chamber 101, and prohibit the first irradiation chamber 101 from starting the irradiation treatment.

When the beam generating device 10 emits the beam to the first irradiation chamber 101, when the system control module 30 determines that the irradiation of the first irradiation chamber 101 is abnormal or the operation data is out of limits according to the received operation data of the shielding door E1 of the first irradiation chamber 101, the operation data of the radiation monitoring assembly 50, the operation data of the patient state monitoring assembly 60, or the operation data of the activity monitoring assembly 70, for example, the opened state data of the shielding door E1 of the first irradiation chamber 101 or the opened signal data of the radiation monitoring assembly 50 or the monitored value of the patient state monitoring assembly 60 exceeds the preset range or the abnormal signal data of the patient state monitoring assembly 60 or the monitored value of the activity monitoring assembly 70 exceeds the preset range or the abnormal signal data of the activity monitoring assembly 70, the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 through the beam control module 20 to end the irradiation treatment of the first irradiation chamber 101.

The shielding door of the irradiation room is closed during irradiation treatment to ensure personnel safety, radiation pollution is avoided, the monitoring value of the radiation monitoring component arranged in the irradiation room can judge whether the beam meets the requirement or is used for calculating the radiation dose received by a patient, the patient state monitoring component can ensure that the state of the patient during treatment is good or no larger displacement is generated to ensure the treatment effect, and the movable monitoring component can ensure that no personnel are accidentally exposed to the radiation or the object moves abnormally to ensure personnel safety and equipment is normal, so that the safety interlocking factor is necessary to be brought into.

In another embodiment of the present invention, radiation therapy system 100 further includes a treatment planning module 80, treatment planning module 80 for storing a treatment plan for the patient. The treatment planning module 80 may interface with the system control module 30 and interact with data to facilitate the system control module 30 in determining whether the radiation of the first radiation chamber 101 presents a safety issue, i.e., the operational data of the radiation treatment system 100 includes treatment planning data retrieved by the system control module 30 from the treatment planning module 80. The content of the data interaction is not particularly limited by the present invention.

The beam control module 20 or the system control module 30 determines that a safety problem exists and performs safety interlocking according to the received operation data of the radiation therapy system 100, including when the system control module 30 determines that an abnormality or treatment plan is completed according to the received treatment plan data before the beam generating device 10 emits the beam to the first irradiation chamber 101 or when the beam is emitted to the first irradiation chamber 101, the safety problem is determined to exist, that is, the safety interlocking mechanism is triggered.

When the system control module 30 does not acquire a compliance treatment plan (consistent with the current patient to be treated) from the treatment plan module 80 before the beam generating device 10 emits the beam to the first irradiation room 101, if the system control module 30 automatically judges that the treatment plan is wrong according to the received treatment plan data, it is determined that the irradiation of the first irradiation room 101 to be started has a safety problem, that is, a safety interlock mechanism is triggered, and the system control module 30 can control the beam generating device 10 to prohibit emission of the beam to the first irradiation room 101 and prohibit the first irradiation room 101 from starting irradiation treatment through the beam control module 20. It will be appreciated that the operator such as a physician may also make a decision (e.g., whether the numbers, patient information, etc. are consistent) and send a signal to the system control module 30 confirming the inconsistency manually, and the system control module 30 determines that the impending irradiation of the first irradiation chamber 101 has a safety issue, i.e., triggers a safety interlock mechanism, based on the received signal data.

When the system control module 30 determines that the treatment plan of the patient in the first irradiation room 101 is completed (e.g., the treatment duration or the treatment dose in the received treatment plan is reached) according to the comparison of the irradiation data of the patient in the first irradiation room 101 and the received treatment plan data while the beam generating device 10 emits the beam to the first irradiation room 101, it determines that the irradiation of the first irradiation room 101 has a safety problem, that is, triggers the safety interlock mechanism, and the system control module 30 can control the beam generating device 10 to stop emitting the beam to the first irradiation room 101 through the beam control module 20, and ends the irradiation treatment of the first irradiation room 101.

The dosage, duration, etc. of the radiation received by the patient during treatment are determined by the treatment plan data, and if the treatment plan is incorrect, the treatment effect is directly affected or the patient is endangered, and the inclusion of the safety interlock factor further ensures the effective operation of the radiation treatment.

In another embodiment of the present invention, a signal of the status of the irradiation room (e.g., including irradiation, waiting to be irradiated, preparing, not in use, etc.) may be set, and the signal may be manually confirmed by an operator such as a doctor according to the condition of the irradiation room, or may be automatically determined and given by the system control module 30 according to the received data. That is, the radiation therapy system operation data further includes signal data of the state of the irradiation room, the beam control module 20 or the system control module 30 determines that there is a safety problem and performs safety interlocking according to the received radiation therapy system 100 operation data, including when the system control module 30 determines that the first irradiation room 101 is not in the state to be irradiated according to the received signal data of the state of the first irradiation room 101 before the beam generating device 10 emits the beam to the first irradiation room 101, if the state of the first irradiation room 101 is a ready or unused signal, determining that there is a safety problem in the irradiation of the first irradiation room 101 to be started, that is, triggering the safety interlocking mechanism, the system control module 30 can control the beam generating device 10 to prohibit the emission beam to the first irradiation room 101 by the beam control module 20, and prohibit the first irradiation room 101 from starting irradiation therapy.

In another embodiment of the present invention, the radiotherapy system further comprises a beam collecting device 90, the beam collecting device 90 may be a container buried in a wall, the beam is collected when the beam is not required, and the beam direction switching assembly 121 transmits the charged particle beam P generated by the charged particle beam generating part 11 to the beam collecting device 90. The beam control module 20 or the system control module 30 may control the beam generating device 10 to stop emitting the beam to the first irradiation chamber 101 by the beam control module 20 by controlling the charged particle beam generating section 11 to stop generating the charged particle beam P; the charged particle beam P generated by the charged particle beam generating unit 11 may be controlled to stop acting on the first neutron beam generating unit 13, that is, the beam generating apparatus 10 may be controlled to separate the beam from the first irradiation chamber 101 by the beam direction switching means 121, for example, the charged particle beam P generated by the charged particle beam generating unit 11 may be controlled to act on the second neutron beam generating unit 13' by the beam direction switching means 121 to generate the neutron beam N irradiated into the second irradiation chamber 101', and the beam may be switched from the first irradiation chamber 101 to the second irradiation chamber 101'; or the charged particle beam P generated by the charged particle beam generating unit 11 is controlled to be directly transmitted to the beam collecting device 90 by the beam direction switching unit 121 without acting on both the first and second neutron beam generating units 13, 13', so that the beam is switched from the first irradiation chamber 101 to the beam collecting device 90. The selection may be automatically determined by the beam control module 20 or the system control module 30 based on the received operational data of the radiation therapy system 100, or may be manually entered by prompting the operator after triggering the safety interlock mechanism. In one embodiment, when the factor triggering the safety interlock is non-beam generating device 10 dependent, such as opening of a mask door of the illumination chamber or patient abnormality, the beam may be selectively cut off from the first illumination chamber 101; when the factor triggering the safety interlock is that the beam generating device 10 is associated with, for example, an accelerator failure, the charged particle beam generating section 11 may be selectively controlled to stop generating the charged particle beam P; it will be appreciated that other arrangements are possible and the invention is not limited in this regard.

In one embodiment, the safety interlock control method further comprises, before switching the beam from the first illumination chamber 101 to the second illumination chamber 101': the beam control module 20 or the system control module 30 determines whether the second irradiation chamber 101 'has a safety problem (whether it is in an unused state and whether the shielding door of the second irradiation chamber 101' is closed) based on the received operation data of the radiation therapy system 100. When it is determined that the second irradiation chamber 101' is in the unused state and the shielding door of the second irradiation chamber 101' is closed, switching the beam from the first irradiation chamber 101 to the second irradiation chamber 101'; when it is determined that the second irradiation chamber 101' is not in the unused state and the shielding door of the second irradiation chamber 101' is not closed, the action of switching the beam from the first irradiation chamber 101 to the second irradiation chamber 101' is not performed and the prompt is made. Specifically, the portion of the beam direction switching assembly 121 corresponding to the first irradiation chamber 101 may be disconnected, and the portion of the beam direction switching assembly 11 corresponding to the second irradiation chamber 101 'may be connected, thereby realizing the switching of the beam from the first irradiation chamber 101 to the second irradiation chamber 101'.

According to the technical solution provided in the embodiments of the present invention, when the beam control module 20 or the system control module 30 determines that there is a safety problem in the irradiation of the first irradiation chamber 101 according to the received operation data of the radiation therapy system 100, the beam generating device 10 is controlled to cut off the beam from the first irradiation chamber 101, so that the beam can be quickly cut off from the first irradiation chamber 101 without shutting down the beam generating device, the safety problem of the first irradiation chamber 101 can be timely solved, and the service life of the beam generating device 10 can be improved while the safety of the radiation therapy system 100 is improved. In addition, the first irradiation chamber 101 and the second irradiation chamber 101' share one beam generating device 10, so that the utilization rate of the beam generating device 10 is improved, and the requirement that a plurality of irradiation chambers are matched for safety interlocking protection simultaneously is met. Any combination of the above optional solutions may be adopted to form an optional embodiment of the present invention, which is not described herein.

In one embodiment of the present invention, the shielding door and the beam direction switching element 121 cooperate to form a safety interlock factor, and the principle of the safety interlock mechanism is described briefly. The shielding doors include, among others, shielding doors of the charged particle beam generating room 102 (such as shielding door a and shielding door B), shielding door C of the beam transmitting room 103, and shielding doors of the irradiation room (shielding door E1 of the first irradiation room and shielding door E2 of the second irradiation room). The beam direction switching unit 121 includes a deflection magnet D1 and a deflection magnet D2 for guiding the irradiation beam into the first irradiation chamber 101 and the second irradiation chamber 101', respectively. Wherein the switching on of deflection magnet D1 and deflection magnet D2 is mutually exclusive, for example: when the deflection magnet D1 is on, the deflection magnet D2 is off; when the deflection magnet D2 is turned on, the deflection magnet D1 is turned off.

Opening of irradiation treatment of irradiation chamber: the shielding gate a, the shielding gate B of the charged particle beam generating chamber 102 and the shielding gate C of the beam transmitting chamber 103 must all be in a closed state; in addition, it is necessary that at least one deflection magnet is turned on and the shielding door of the corresponding irradiation chamber is closed, for example, the deflection magnet D1 is turned on and the shielding door E1 of the first irradiation chamber is closed; or the deflection magnet D2 is switched on and the shielding door E2 of the second irradiation chamber is closed.

In short, when the shielding doors a, B, and C are all in the closed state, the deflection magnet D1 is turned on and the shielding door E1 of the corresponding first irradiation chamber 101 is in the closed state, the charged particle beam generating section 11 reaches the beam exit condition; or when the shielding doors a, B, and C are all in the closed state, the deflection magnet D2 is turned on and the shielding door E2 of its corresponding second irradiation chamber 101' is in the closed state, the charged particle beam generating section 11 reaches the beam exit condition. That is, when the system control module receives an instruction to start irradiation of the first or second irradiation chamber and determines that there is no safety problem in the irradiation of the irradiation chamber by performing the safety interlock determination, the system control module controls the charged particle beam generator 11 to generate the charged particle beam P (the ion source 111, the accelerator 112, and the accelerator assist device 113 are operated to the beam-out state), and the charged particle beam P acts on the corresponding neutron beam generator to generate a neutron beam to irradiate the irradiation chamber, so that the irradiation treatment of the irradiation chamber is started.

Closure of irradiation treatment of irradiation chamber: during the irradiation treatment execution of the first irradiation chamber 101, if at least one of the shield doors (for example, at least one of the shield doors A, B, C, E1) is opened or the state of the deflection magnet D1 is abnormal (for example, the state is changed from the on state to the off state by accident), it is determined that there is a safety problem in the irradiation of the first irradiation chamber 101, and the irradiation treatment of the first irradiation chamber 101 is terminated by cutting off the deflection magnet D1 or stopping the charged particle beam generation section 11 from generating the charged particle beam P (for example, turning off the accelerator 112 or turning off the ion source 111), and then cutting off the beam from the first irradiation chamber 101. When the deflection magnet D1 is turned off to cut the beam from the first irradiation chamber 101, if it is determined that the second irradiation chamber 101 'is in an unoccupied state and the shielding door is closed, the deflection magnet D2 may be turned on, and the beam is switched from the first irradiation chamber 101 to the second irradiation chamber 101'; it is also possible to keep neither deflection magnet D1, D2 on, and the beam is switched from the first irradiation chamber to the beam dump 90.

During the irradiation treatment of the second irradiation chamber 101', if at least one of the shielding doors (e.g., at least one of the shielding doors A, B, C, E) is opened or the state of the deflection magnet D2 is abnormal (e.g., accidentally switched from the on state to the off state), it is determined that the second irradiation chamber 101' has a safety problem, and the beam can be cut off from the second irradiation chamber 101 'to terminate the irradiation treatment of the second irradiation chamber 101' as long as the deflection magnet D2 is turned off or the charged particle beam generator 11 is stopped from generating the charged particle beam P (e.g., the accelerator 112 is turned off or the ion source 111 is turned off). When the deflection magnet D2 is turned off to separate the beam from the second irradiation chamber 101', if the first irradiation chamber 101 is determined to be in an unoccupied state and the shielding door is closed, the deflection magnet D1 may be turned on, and the beam is switched from the second irradiation chamber 101' to the first irradiation chamber 101; it is also possible to keep neither deflection magnet D1, D2 on, and the beam is switched from the second irradiation chamber 101' to the beam dump 90.

In order to simplify the explanation of the principles of the safety interlock mechanism, the shielding gate and the deflection magnet are merely used as examples of the safety interlock mechanism, and it should be understood that other factors (such as ion source, accelerator auxiliary equipment, neutron beam generating section, beam monitoring assembly, radiation monitoring assembly, treatment planning module, etc.) may be added in addition to the shielding gate and the deflection magnet to cooperate to form the safety interlock mechanism, which is not limited in this regard. By incorporating various devices and components into the safety interlock factor, the safety of the radiation therapy system is effectively improved, and the effective utilization of the radiation therapy system is enhanced.

FIG. 6 is a flow chart of a method for controlling safety interlock of a radiation therapy system according to another embodiment of the present invention, which is exemplified by neutron irradiation treatment in a first irradiation chamber. The safety interlock control method may be performed by the safety interlock control system 700 in a radiation therapy system. The safety interlock control system 700 may include control software and a carrier for executing a control program, may include a user input interface and a feedback display interface, and may further include a processor module, a data acquisition module, a device connection port of a beam generating device or an irradiation room, etc., which is not particularly limited in this embodiment of the present invention. As shown in fig. 6, the safety interlock control method includes:

s601: and receiving login information of the user.

S602: after receiving the login information of the user in step S601, it is determined whether the login of the user is successful.

When the user does not login successfully, returning to the step S601; when the user login is successful, step S603 is performed.

S603: treatment parameters are received.

The user may also verify the status of the treatment device or patient before and after receiving the treatment parameters. The treatment parameters may be manually entered by the user or may be treatment parameters in treatment plan data obtained from a treatment plan module, as the invention is not limited in this regard.

S604: after receiving the treatment parameters in step S603, an irradiation treatment instruction input by the user to start the first irradiation chamber 101 is received.

S605: after receiving the irradiation treatment instruction from the user to start the first irradiation chamber 101 in step S604, the control right of the beam generating device 10 is obtained.

S606: after step S605, it is determined whether irradiation treatment can be started for the first irradiation chamber 101 according to the safety interlock mechanism.

Specifically, it is determined whether or not there is a safety problem in the irradiation of the first irradiation chamber 101 that is to be started. When there is a safety problem in the irradiation of the first irradiation chamber 101 to be started, step S607 is performed; when there is no safety problem in the irradiation of the first irradiation chamber 101 to be started, and the treatment can be started, step S608 is performed.

S607: instructions to begin treatment are not executed and a prompt to trigger a safety interlock mechanism is popped up.

For example, the cues may be operational data overrun, equipment failure, deflection magnet not on, shielding door not off, insufficient target life, inconsistent collimator, patient anomalies, treatment planning errors, etc., as the invention is not limited in this regard. The user solves the safety problem according to the prompt, if the problem is solved, such as closing the corresponding shielding door, the user manually selects to determine that the problem is solved, the step S606 is returned, and the safety interlocking judgment before starting irradiation is performed again; if the problem is temporarily not resolved, e.g. the device fails severely, the user manually chooses to determine that the problem is not resolved, step S612 is performed, ending the irradiation treatment of the patient and releasing control of the beam generating device 10.

S608: the control beam generating device 10 generates a therapeutic beam, and starts irradiation therapy on the patient 200 in the first irradiation room 101.

Specifically, the charged particle beam generator 11 is controlled to generate a charged particle beam P and the beam transmission unit 12 is controlled to transmit the charged particle beam P generated by the charged particle beam generator 11 to the first neutron beam generator 13, and the charged particle beam P acts on the first neutron beam generator 13 to generate a therapeutic neutron beam N and irradiates the patient 200 on the treatment table 40 provided in the first irradiation chamber 101, thereby performing irradiation treatment on the patient 200.

S609: after the irradiation treatment is started on the patient in the first irradiation room 101 in step S608, it is determined in real time whether or not the irradiation treatment can be continued on the first irradiation room 101 according to the safety interlock mechanism.

That is, it is determined in real time whether or not there is a safety problem with the irradiation of the first irradiation chamber 101, and when there is no safety problem with the irradiation of the first irradiation chamber 101, step S610 is performed; when there is a safety problem in the irradiation of the first irradiation chamber 101, step S611 is performed.

S610: irradiation treatment is continuously performed on the patient 200 in the first irradiation room 101, and the judgment is continuously performed in S609.

S611: the irradiation treatment of the patient 200 in the first irradiation chamber 101 is stopped and a prompt triggering the safety interlock mechanism is ejected.

For example, the prompt may be an overrun of operational data, equipment failure, a non-switching on of the deflection magnet, an opening of a shield door, an abnormality of the patient, or completion of a treatment plan, etc., as the invention is not limited in this regard. The user solves the safety problem according to the prompt, if the problem is solved, such as closing the corresponding shielding door, etc., the user manually selects to determine that the problem is solved, the process returns to step S608, and the irradiation treatment of the patient 200 of the first irradiation room 101 is started again; if the problem is temporarily not solved, e.g. the apparatus fails seriously, the user manually selects to determine that the problem is not solved, step S612 is performed, ending the irradiation treatment of the patient 200 of the first irradiation chamber 101 and releasing the control of the beam generating device 10; or prompting the completion of the treatment plan, the user manually selects to determine that the irradiation is completed, and step S612 is performed to end the irradiation treatment of the patient 200 of the first irradiation chamber 101 and release the control of the beam generating device 10.

S612: the irradiation treatment of the patient 200 of the first irradiation chamber 101 is ended and the control of the beam generating device 10 is released.

S613: after the irradiation treatment is ended in step S612, log-out information of the user is received.

It can be understood that in the above steps, after the safety interlock determines that the safety problem exists, according to the factor triggering the safety interlock, the prompt triggering the safety interlock mechanism may be popped up first, and the user decides whether the irradiation treatment can be started or continued according to the prompt, for example, if some operation data exceeds the preset range, the amplitude is not large, and the doctor determines that the irradiation treatment is still within the safety range according to experience, so that the irradiation treatment can be started or continued.

According to the technical scheme provided by the embodiment of the invention, the safety problem is monitored before the irradiation treatment is started and in the irradiation treatment by the safety interlocking mechanism formed by a plurality of safety interlocking factors, so that the safety of the radiotherapy system is improved.

Any combination of the above optional solutions may be adopted to form an optional embodiment of the present invention, which is not described herein.

The implementation process of the functions and roles of each module in the above device is specifically shown in the implementation process of the corresponding steps in the above method, and will not be described herein again.

FIG. 7 is a block diagram of a safety interlock control system 700 of a radiation therapy system according to one embodiment of the present invention.

Referring to FIG. 7, the safety interlock control system 700 includes a processing component 710 that further includes one or more processors and memory resources represented by memory 720 for storing instructions, such as applications, that can be executed by the processing component 710. The application programs stored in memory 720 may include one or more modules that each correspond to a set of instructions. In addition, the processing component 710 is configured to execute instructions to perform the safety interlock control method of the radiation therapy system described above.

The safety interlock control system 700 may also include a power source component configured to perform power management of the safety interlock control system 700, a wired or wireless network interface configured to connect the safety interlock control system 700 to a network, and an input output (I/O) interface. The safety interlock control system 700 may operate based on an operating system stored in the memory 720, such as Windows Server ^TM ，Mac OS X ^TM ，Unix ^TM ，Linux ^TM ，FreeBSD ^TM Or the like。

A non-transitory computer readable storage medium that, when executed by a processor of the safety interlock control system 700, enables the safety interlock control system 700 to perform a method of safety interlock control of any of the radiation therapy systems described above.

Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present invention.

It will be clear to those skilled in the art that, for convenience and brevity of description, specific working procedures of the above-described systems, apparatuses and units may refer to corresponding procedures in the foregoing method embodiments, and are not repeated herein.

In the several embodiments provided in this application, it should be understood that the disclosed systems, devices, and methods may be implemented in other manners. For example, the apparatus embodiments described above are merely illustrative, e.g., the division of the units is merely a logical function division, and there may be additional divisions when actually implemented, e.g., multiple units or components may be combined or integrated into another system, or some features may be omitted or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed with each other may be an indirect coupling or communication connection via some interfaces, devices or units, which may be in electrical, mechanical or other form.

The units described as separate units may or may not be physically separate, and units shown as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

In addition, each functional unit in the embodiments of the present invention may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit.

The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present invention may be embodied essentially or in a part contributing to the prior art or in a part of the technical solution in the form of a software product stored in a storage medium, comprising several instructions for causing a computer device (which may be a personal computer, a server, a network device, or the like) to perform all or part of the steps of the method according to the embodiments of the present invention. And the aforementioned storage medium includes: a usb disk, a removable hard disk, a Read-Only Memory (ROM), a random access Memory (Random Access Memory, RAM), a magnetic disk, or an optical disk, or other various media capable of storing program verification codes.

In addition, it should be noted that the combination of the technical features described in the present invention is not limited to the combination described in the claims or the combination described in the specific embodiments, and all the technical features described in the present invention may be freely combined or combined in any manner unless contradiction occurs between them.

It should be noted that the above-mentioned embodiments are merely examples of the present invention, and it is obvious that the present invention is not limited to the above-mentioned embodiments, and many similar variations are possible. All modifications attainable or obvious from the present disclosure set forth herein should be deemed to be within the scope of the present disclosure.

It should be understood that the first, second, etc. qualifiers mentioned in the embodiments of the present invention are only used for more clearly describing the technical solutions of the embodiments of the present invention, and should not be used to limit the protection scope of the present invention.

The foregoing is merely illustrative of the preferred embodiments of the present invention, and is not intended to limit the scope of the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A radiation therapy system, comprising:

an irradiation chamber;

a beam generating device including a charged particle beam generating portion and a beam transmitting portion including a beam direction switching means, and a neutron beam generating portion;

Beam collecting means;

the charged particle beam generated by the charged particle beam generating device acts on the neutron beam generating section to generate a therapeutic neutron beam to irradiate into the irradiation chamber; or the charged particle beam generated by the charged particle beam generating device cuts the beam from the irradiation chamber to the beam collecting device through the beam direction switching component;

a beam control module capable of controlling the charged particle beam generating device to generate the charged particle beam and receiving operation data of the charged particle beam generating device;

a system control module capable of controlling the charged particle beam generating device to generate the charged particle beam and receiving operational data of the radiation therapy system, the operational data of the radiation therapy system including operational data of the charged particle beam generating device, by the beam control module;

the beam control module judges whether a safety problem exists according to the received operation data of the charged particle beam generating device or whether the system control module judges whether the safety problem exists according to the received operation data of the radiotherapy system.

2. The radiation therapy system of claim 1, wherein the operational data of the charged particle beam generating device comprises operational data of the charged particle beam generating portion or operational data of the beam delivery portion comprising operational data of the beam direction switching assembly.

3. The radiation therapy system of claim 2, wherein said charged particle beam generating portion comprises an ion source, an accelerator, and an accelerator auxiliary device, and wherein said charged particle beam generating portion operational data comprises operational data of said ion source or operational data of said accelerator auxiliary device or total fault signal data of said ion source, accelerator, and accelerator auxiliary device.

4. The radiation therapy system of claim 2, further comprising a charged particle beam generation chamber housing the charged particle beam generation section, a beam transport chamber housing the beam direction switching assembly, a shielding door of the charged particle beam generation chamber, and a shielding door of the beam transport chamber, the operational data of the radiation therapy system further comprising operational data of the shielding door of the charged particle beam generation chamber or operational data of the shielding door of the beam transport chamber.

5. The radiation therapy system of claim 1, wherein said charged particle beam generating device comprises a charged particle beam monitoring assembly, and wherein said charged particle beam generating device operational data comprises operational data of said charged particle beam monitoring assembly.

6. The radiation therapy system of claim 1, wherein said beam generating device further comprises a neutron beam monitoring assembly, and wherein said radiation therapy system operational data further comprises operational data of said neutron beam monitoring assembly or operational data of said neutron beam generating portion.

7. The radiation therapy system of claim 1, further comprising a shielded gate of the radiation chamber and a radiation monitoring assembly disposed in the radiation chamber, the operational data of the radiation therapy system further comprising operational data of the shielded gate of the radiation chamber or operational data of the radiation monitoring assembly.

8. The radiation therapy system of claim 1, further comprising a patient status monitoring component or an activity monitoring component, wherein the radiation therapy system operational data further comprises operational data of the patient status monitoring component or operational data of the activity monitoring component.

9. The radiation therapy system of claim 1, further comprising a treatment planning module, wherein the radiation therapy system operational data further comprises treatment planning data retrieved by the system control module from the treatment planning module.

10. A method of safety interlock control of a radiation therapy system according to any one of claims 1-9, wherein the control method comprises:

before the beam generating device generates a therapeutic neutron beam to start to irradiate into the irradiation chamber, the beam control module prohibits the charged particle beam generating device from generating the charged particle beam by the beam control module when the beam control module determines that the irradiation of the irradiation chamber to be started has a safety problem according to the received operation data of the charged particle beam generating device or the received operation data of the radiotherapy system; or alternatively

When the beam control module determines that there is a safety problem in the irradiation of the irradiation chamber according to the received operation data of the charged particle beam generating device or the received operation data of the radiotherapy system when the beam generating device generates a therapeutic neutron beam and irradiates the irradiation chamber, the beam control module or the system control module controls the charged particle beam generating device to stop generating the charged particle beam or controls the charged particle beam generated by the charged particle beam generating device to stop acting on the neutron beam generating part and cuts off the beam from the irradiation chamber to a beam collecting device through a beam direction switching component.