CN112540062A - Sample detection method and device - Google Patents
Sample detection method and device Download PDFInfo
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- CN112540062A CN112540062A CN201910893248.8A CN201910893248A CN112540062A CN 112540062 A CN112540062 A CN 112540062A CN 201910893248 A CN201910893248 A CN 201910893248A CN 112540062 A CN112540062 A CN 112540062A
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
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- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N35/00584—Control arrangements for automatic analysers
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- G01N2035/00752—Type of codes bar codes
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Abstract
The present application relates to a sample detection method and apparatus. The method comprises the following steps: scanning the identification code of the assay table through an identification code scanner to acquire first information; the first information includes main scaling curve information of the detection item; scanning the identification code of the sample to be detected through the identification code scanner to obtain second information, wherein the second information comprises detection item information of the sample to be detected; acquiring third information by scanning the reagent card identification code, wherein the third information comprises detection item information; adding a sample to be detected in a sample tube to be detected to a reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data corresponding to a detection item; and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected. The sample detection method and the sample detection device can improve the sample detection efficiency and reduce the test cost.
Description
Technical Field
The present application relates to the field of in vitro diagnostic techniques, and more particularly, to a method and apparatus for sample detection.
Background
With the increasing competition of in vitro diagnostic techniques, especially point-of-care test (POCT), the requirements for efficiency and cost control of sample detection are higher and higher. How to make users operate instruments more conveniently and easily becomes a core competitive element in the industry. In a conventional immediate diagnosis sample detection method, sample information is generally manually input, an IC card or a memory card is used to carry and introduce reagent main calibration curve information, and then sample detection is performed.
However, this method for detecting a sample has problems of low efficiency and high cost.
Disclosure of Invention
In view of the above, it is desirable to provide a sample detection method and apparatus capable of improving efficiency and reducing test cost.
A method of sample detection, the method comprising:
providing an identification code of the test table, and scanning the identification code of the test table through an identification code scanner to acquire first information; the first information includes main scaling curve information of the detection item; providing a sample tube to be detected, wherein a sample identification code to be detected is arranged on the sample tube to be detected, and scanning the sample identification code to be detected through the identification code scanner to obtain second information, wherein the second information comprises detection item information of a sample to be detected;
providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and third information is obtained by scanning the reagent card identification code and comprises the detection item information;
adding a sample to be detected in the sample tube to be detected to the reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data corresponding to the detection item;
and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected.
In one embodiment, the identification code scanner is a two-dimensional code scanner.
In one embodiment, the verification table identification code is a two-dimensional code; the reagent card identification code is a two-dimensional code.
In one embodiment, the obtaining the third information by scanning the reagent card identification code includes:
and scanning the reagent card identification code through the two-dimensional code scanner to acquire third information.
In one embodiment, the reagent card identification code is a two-dimensional code; the obtaining of the third information by scanning the reagent card identification code includes:
and scanning the reagent card identification code which is the two-dimensional code by the two-dimensional code scanner to obtain third information.
In one embodiment, the obtaining of the reaction data corresponding to the detection item includes:
acquiring a fluorescence signal; the fluorescence signal is generated by the reaction of a sample to be detected and a reagent in the reagent card under the excitation of exciting light;
converting the fluorescence signal into reaction data.
In one embodiment, the test table identification code and the sample identification code to be tested are scanned in the scanning direction of the identification code scanner by holding the test table and the sample tube to be tested.
In one embodiment, the reagent card identification code is scanned in the scanning direction of the scanner by holding the reagent card.
A sample testing device, the device comprising:
the identification code scanning module is used for scanning the identification code of the assay table, the sample identification code and the reagent card identification code to acquire first information, second information and third information;
the reaction data acquisition module is used for generating a fluorescence signal by reacting a sample with a reagent in the reagent card and converting the fluorescence signal into reaction data;
and the calculation module is used for calculating the reaction data based on the first information, the second information and the third information to obtain a detection result.
In one embodiment, the identification code scanning module is an identification code scanner that is built into the sample detection device.
In one embodiment, the sample detection device further comprises a transparent baffle, and the transparent baffle is arranged in the scanning direction of the identification code scanner.
A method of sample detection, the method comprising:
providing an identification code of the assay table, and scanning the identification code of the assay table at a first height through a first identification code scanner to obtain first information; the first information includes main scaling curve information of the detection item;
providing a sample tube to be tested, and acquiring second information; the second information comprises detection item information of the sample to be detected;
providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and the reagent card identification code is scanned at a second height through the first identification code scanner to obtain third information, wherein the third information comprises the detection item information;
adding a sample to be detected in the sample tube to be detected to the reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data of the detection item;
and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected.
In one embodiment, the obtaining of the reaction data corresponding to the detection item includes:
acquiring a fluorescence signal; the fluorescence signal is generated by the reaction of the sample and the reagent in the reagent card under the excitation of the exciting light;
converting the fluorescence signal into reaction data.
In one embodiment, the obtaining the second information includes:
scanning the identification code of the sample to be detected through a second identification code scanner to obtain second information; the second information includes detection item information of the sample to be detected.
In one embodiment, the second identification code scanner is a handheld identification code scanner.
A sample testing device, the device comprising:
the identification code scanning module is used for scanning the identification code of the assay table at a first height to obtain first information, and scanning the identification code of the reagent card at a second height to obtain second information;
the reaction data acquisition module is used for acquiring reaction data corresponding to the detection items;
the second information acquisition module is used for acquiring second information, and the second information comprises detection item information of a sample to be detected;
and the calculation module is used for calculating the reaction data based on the first information, the second information and the third information to obtain a detection result.
In one embodiment, the identification code scanning module is a first identification code scanner, and the first identification code scanner is built in the sample detection device.
In one embodiment, the detection device is further provided with a first scanning channel and a second scanning channel.
In one embodiment, the second scanning channel is located at a second height and comprises a card slot for placing the reagent card, and the card slot and the reagent card placed on the card slot move to the scanning direction of the first scanner, and the first scanner scans the reagent card identification code on the reagent card at the second height.
In one embodiment, the first scanning channel is located at a first elevation, the assay meter identification code is placed in a scanning direction of the first identification code scanner by the first scanning channel, and the first identification code scanner scans the reagent card identification code on the reagent card at the first elevation.
In one embodiment, the second scanning channel is located above the first scanning channel.
In one embodiment, the detection apparatus further includes a second identification code scanner, which is externally disposed on the sample detection apparatus and used for scanning the identification code of the sample to be detected.
The sample detection method and the device provide the identification code of the assay table, and the identification code scanner scans the identification code of the assay table to acquire first information; the first information includes main scaling curve information of the detection item; providing a sample tube to be detected, wherein a sample identification code is arranged on the sample tube to be detected, and scanning the sample identification code to be detected through an identification code scanner to obtain second information, wherein the second information comprises detection item information of a sample to be detected; providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and third information is obtained by scanning the reagent card identification code and comprises detection item information; adding a sample to be detected in a sample tube to be detected to a reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data corresponding to a detection item; and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected. The assay table identification code, the sample identification code and the reagent card identification code are scanned by the identification code scanner to respectively obtain first information, second information and third information, and reaction data are calculated based on the first information, the second information and the third information to obtain a detection result, so that the sample detection efficiency is improved; the first information, the second information and the third information are stored in the form of identification codes, so that the probability of failure of information storage is reduced, and the reliability of information storage is improved; the assay table identification code, the sample identification code to be detected and the reagent card identification code can be obtained in any picture mode without being transmitted through an entity storage carrier, so that the information transmission efficiency is improved, the operation is more convenient and fast, and the hardware cost is reduced; when the identification code is damaged or polluted, the identification code can be acquired again in other modes, such as picture transmission, fax printing and the like, so that the problem that information cannot be acquired again after hardware is damaged is avoided, and the fault tolerance rate is high.
Drawings
FIG. 1 is a schematic flow chart of a sample detection method according to an embodiment;
FIG. 2 is a diagram illustrating an embodiment of an identification code scanner scanning an identification code of an assay table;
FIG. 3 is a diagram illustrating a page scanned for identification codes of a test table in one embodiment;
FIG. 4 is a diagram illustrating an embodiment of an identification code scanner scanning an identification code of a sample under test;
FIG. 5 is a schematic diagram of a page scanned with an identification code of a sample under test in one embodiment;
FIG. 6 is a schematic representation of an embodiment of an identification code scanner scanning an identification code of a reagent card;
FIG. 7 is a schematic diagram of a page scanned for reagent card identifiers in one embodiment;
FIG. 8 is a schematic view of a sample testing device in one embodiment;
FIG. 9 is a schematic view of the internal structure of the sample testing device in one embodiment;
FIG. 10 is a schematic flow chart of a sample detection method according to another embodiment;
FIG. 11 is a schematic view of an identification code scanner scanning an identification code of an assay table in another embodiment;
FIG. 12 is a schematic view of a sample testing device and a portion of the internal structure of the sample testing device in one embodiment;
FIG. 13 is a schematic view of an alternative embodiment of an identification code scanner scanning an identification code of a reagent card;
FIG. 14 is a schematic view of a sample detection method in another embodiment;
FIG. 15 is a diagram showing an internal structure of a computer device according to an embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
In one embodiment, as shown in fig. 1, there is provided a sample detection method comprising the steps of:
102, providing an identification code of the test table, and scanning the identification code of the test table through an identification code scanner to acquire first information; the first information includes main scaling curve information of the detection item. The test table identification code refers to an identification code storing information of the test table. The identification code scanner scans the identification code of the laboratory sheet, so that the information of the laboratory sheet, namely the first information, can be acquired. The main calibration curve information refers to the corresponding relationship between the pre-calibrated known sample detection result and the reaction data, that is, the reaction data obtained by sample detection is compared and calculated with the main calibration curve information, so that the detection result can be obtained. The information on the master calibration curve is usually different for different test items or for reagents produced in different batches for the same test item. In the first information, the primary calibration curve information of one or more kinds of detection items may be included. The first information may also include parameters, algorithms, units, formulas, etc. of the reagent card.
The chemical examination table identification code is a two-dimensional identification code, and the identification code scanner is a two-dimensional code scanner. It should be noted that the two-dimensional code scanner may not only scan the two-dimensional identification code, but also scan the one-dimensional identification code or other forms of identification codes, and is not limited thereto.
As shown in fig. 2, 200 is a sample detection device, 202 is a test table, a test table identification code 204 is provided on the test table 202, and the test table identification code 204 is a two-dimensional identification code. The identification code scanner is arranged in the sample detection device 200, and the test table identification code 204 of the test table 202 is placed in the scanning direction of the identification code scanner, so that the test table identification code can be scanned to obtain first information.
As shown in fig. 3, after the identification code of the assay table is scanned by the identification code scanner, the first information can be obtained. The first information is the serial number # # 12365464316 of the identification code of the test table, the state of the test table is scanned, the detected items are CTnl, the batch number is 20195121, and the like.
And 104, providing a sample tube to be detected, wherein a sample identification code to be detected is arranged on the sample tube to be detected, and scanning the sample identification code to be detected through an identification code scanner to obtain second information, wherein the second information comprises detection item information of the sample to be detected.
The sample tube to be measured refers to a test tube storing a sample to be measured. The sample to be tested can be a medical test sample such as blood, urine and the like. The sample tube to be detected is provided with a sample identification code to be detected, and the sample identification code to be detected can be one of a one-dimensional identification code, a two-dimensional identification code and identification codes in other forms.
After the identification code scanner scans the identification code of the sample to be detected, the second information can be obtained. The second information includes detection item information of the sample to be detected. The detection item information includes Procalcitonin (PCT), troponin T (cTnT), human chorionic gonadotropin (beta-HCG), and the like.
As shown in fig. 4, 400 is a sample testing device, 402 is a sample tube to be tested, and a sample identification code 404 is disposed on the sample tube 402. The identification code scanner is arranged in the sample detection device 400, and the sample identification code 404 of the sample tube 402 to be detected is placed in the scanning direction of the identification code scanner, so that the sample identification code to be detected can be scanned to obtain the second information.
As shown in fig. 5, after the identification code scanner scans the identification code of the sample to be tested, the second information can be obtained. The second information is the identification code 20190516302, the type of the sample to be tested is serum/plasma, and the items to be tested are cardiostatin and H-proteinase. When the 'obtaining' button is clicked, the information of the sample to be tested, such as name, date of birth, sex, bed number, department, and the like, can be obtained.
And 106, providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and scanning the reagent card identification code to obtain third information, wherein the third information comprises detection item information.
The reagent card contains a reagent which can react with a sample to be detected. The reagent card is provided with a reagent card identification code which can be one of a one-dimensional identification code, a two-dimensional identification code and other forms of identification codes. The reagent card identification code stores third information, and the third information includes detection item information, such as a reagent name, a reagent batch number, a production date and the like corresponding to the detection item.
As shown in FIG. 6, 600 denotes a sample detection device, 602 denotes a reagent card, and a reagent card identification code 604 is provided on the reagent card 602. The identification code scanner is built in the sample detection device 600, and the reagent card identification code 604 of the reagent card 602 is placed in the scanning direction of the identification code scanner, so that the reagent card identification code can be scanned to obtain the third information.
As shown in fig. 7, after the reagent card identification code is scanned by the identification code scanner, the third information such as the reagent card item, the lot number information and the sample type can be obtained, and after the "start" button in the page is clicked, the first information such as the calculation parameters of the laboratory sheet can be inquired.
And 108, adding the sample to be detected in the sample tube to be detected to the reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data corresponding to the detection item.
And adding the sample to be detected in the sample tube to be detected to the reagent card, so that the sample to be detected and the reagent in the reagent card fully react. It is understood that the reaction is generally a chemical reaction, and reaction data corresponding to the detection item can be obtained through the reaction.
In one embodiment, after the sample to be tested and the reagent in the reagent card react, an optical signal can be emitted, and the optical signal can be acquired by the sensor and converted into an electrical signal, that is, reaction data. In another embodiment, the electrical signal can be directly obtained after the reaction between the sample to be tested and the reagent in the reagent card.
And step 110, calculating the reaction data based on the first information, the second information and the third information to obtain a detection result of the sample to be detected.
The first information comprises the main calibration curve information of one or more items, the second information comprises the detection item information of the sample to be detected, and the detection item of the sample to be detected in the second information can be matched with the one or more items in the first information to obtain the main calibration curve information of the detection item. The third information includes information on the detection items of the reagent card. And calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected.
In one embodiment, the first information further includes a calculation parameter and a calculation formula of the detection item, and the detection result can be obtained by inputting the reaction data and the calculation parameter into the calculation formula corresponding to the detection item. For example, the assay result may be PCT 0.3ug/L, cTnT 0.4. mu.g/L, β -HCG 10mIU/ml, etc.
The sample detection method comprises the steps of providing an identification code of the assay table, and scanning the identification code of the assay table through an identification code scanner to obtain first information; the first information comprises main calibration curve information of the detection item, and the identification code of the assay table is a two-dimensional identification code; providing a sample tube to be detected, wherein a sample identification code is arranged on the sample tube to be detected, and scanning the sample identification code to be detected through an identification code scanner to obtain second information, wherein the second information comprises detection item information of a sample to be detected; providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and third information is obtained by scanning the reagent card identification code and comprises detection item information; adding a sample to be detected in a sample tube to be detected to a reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data corresponding to a detection item; and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected. The assay table identification code, the sample identification code and the reagent card identification code are scanned by the identification code scanner to respectively obtain first information, second information and third information, and reaction data are calculated based on the first information, the second information and the third information to obtain a detection result, so that the sample detection efficiency is improved; the first information, the second information and the third information are stored in the form of identification codes, so that the probability of failure of information storage is reduced, and the reliability of information storage is improved; the assay table identification code, the sample identification code to be detected and the reagent card identification code can be obtained in any picture mode without being transmitted through an entity storage carrier, so that the information transmission efficiency is improved, the operation is more convenient and fast, and the hardware cost is reduced; when the identification code is damaged or polluted, the identification code can be acquired again in other modes, such as picture transmission, fax printing and the like, so that the problem that information cannot be acquired again after hardware is damaged is avoided, and the fault tolerance rate is high.
It will be appreciated that conventional methods of sample detection typically require the downloading or uploading of sample information, reagent card information, etc. over a network. However, in the case of poor network conditions or no network, the conventional sample detection method cannot realize information downloading or uploading through the network, and thus cannot realize sample detection. The identification code scanner scans the identification code of the assay table, the identification code of the sample to be detected and the identification code of the reagent card, so that the first information, the second information and the third information can be acquired, the use of a network is avoided, and the application range of sample detection is widened.
In one embodiment, the assay table identifier is a two-dimensional code; the reagent card identification code is a two-dimensional code.
In addition, because the assay table and the reagent card store information and are different in production process, the common scheme in the field is that the assay table and the reagent card information are stored and read in different manners (for example, the assay table uses a magnetic card to store information, and the reagent card uses a one-dimensional code to store information). The invention creatively integrates the information input mode, overcomes the difference of the production process, designs the adaptive complete machine structure and the scanning control flow, and realizes the scanning of the assay table identification code which is the two-dimensional code and the reagent card identification code which is the two-dimensional code by the same identification code scanner.
In one embodiment, the third information is obtained by scanning the reagent card identification code, comprising: and scanning the reagent card identification code through a two-dimensional code scanner to obtain third information.
The identification code scanner is a two-dimensional code scanner.
In one embodiment, the reagent card identification code is a two-dimensional code; obtaining third information by scanning the reagent card identification code, comprising: and scanning the reagent card identification code of the two-dimensional code by a two-dimensional code scanner to obtain third information.
And when the reagent card identification code is the two-dimensional code, scanning the reagent card identification code which is the two-dimensional code through a two-dimensional code scanner to obtain third information.
In one embodiment, acquiring reaction data corresponding to the detection item includes: acquiring a fluorescence signal; the fluorescence signal is generated by the reaction of the sample to be detected and the reagent in the reagent card under the excitation of the exciting light; the fluorescence signal is converted into reaction data.
The sample to be tested reacts with the reagent in the reagent card and can generate a fluorescence signal under the excitation of the exciting light. When a fluorescent signal is generated, it can be collected by a photosensor in the sample detection device and converted into reaction data.
In one embodiment, the test table identification code and the sample identification code to be tested are scanned by holding the test table and the sample tube to be tested in the scanning direction of the identification code scanner.
It will be appreciated that the direction in which the forward path swept by the scanning light line of the identification code scanner is aligned is the scan direction. Will change the laboratory sheet, the sample pipe that awaits measuring places in identification code scanner the place ahead to will change the laboratory sheet identification code of laboratory sheet, the sample pipe that awaits measuring sample identification code and identification code scanner of awaiting measuring in opposite directions, make the identification code scanner can scan laboratory sheet identification code and the sample identification code that awaits measuring, thereby obtain first information and second information.
In one embodiment, the reagent card identification code is scanned in a scanning direction of the scanner by holding the reagent card.
A sample testing device comprising: the identification code scanning module is used for scanning the identification code of the assay table, the sample identification code and the reagent card identification code to acquire first information, second information and third information; the reaction data acquisition module is used for acquiring a fluorescence signal generated by the reaction of the sample and the reagent in the reagent card and converting the fluorescence signal into reaction data; and the calculation module is used for calculating the reaction data based on the first information, the second information and the third information to obtain a detection result.
The sample detection device can comprise an identification code scanning module, a reaction data acquisition module and a calculation module. The identification code scanning module can be an identification code scanner; the reaction data acquisition module can be a sensor and is used for acquiring reaction data; the calculation module may be a CPU in the sample detection apparatus, and is configured to calculate the detection result.
In one embodiment, the identification code scanning module is an identification code scanner that is built into the sample detection device.
In one embodiment, the sample detection device further comprises a transparent baffle, and the transparent baffle is arranged in the scanning direction of the identification code scanner.
The transparent baffle can be arranged outside the sample detection device, and the transparent baffle is arranged in the scanning direction of the identification code scanner, so that the identification code scanner can scan the identification code through the transparent baffle.
As shown in FIG. 8, 800 is a sample detection device, and 802 is a transparent barrier. An identification code scanner is provided at a position of the transparent barrier in the sample detection device 800, and as shown in fig. 9, 900 is an internal structure of the sample detection device 800, and 902 is an identification code scanner. When the identification code is placed in the transparent barrier 802, i.e., in the scanning direction of the identification code scanner 902, the identification code may be scanned and information may be obtained.
In one embodiment, as shown in fig. 10, a method of sample detection, comprises:
As shown in fig. 11, 1100 is a part of the internal structure of the sample detection apparatus, 1102 is a first identification code scanner, 1104 is an assay table, and the assay table 1104 is provided with an assay table identification code. Move the chemical examination table to the scanning direction of first identification code scanner, and first identification code scanner scans the chemical examination table identification code at first height, can scan complete chemical examination table identification code to acquire first information.
According to the sample detection method, the identification code of the assay table is scanned at the first height through the first identification code scanner to obtain first information, the sample tube to be detected is provided to obtain second information, the identification code of the reagent card is scanned at the second height through the first identification code scanner to obtain third information, and reaction data is calculated based on the first information, the second information and the third information to obtain a detection result, so that the sample detection efficiency is improved; the first information, the second information and the third information are stored in the form of identification codes, so that the probability of failure of information storage is reduced, and the reliability of information storage is improved; the assay table identification code, the sample identification code to be detected and the reagent card identification code can be acquired through any picture or network downloading mode, and transmission through an entity storage carrier is not needed, so that the information transmission efficiency is improved, the method is more convenient and fast, and the hardware cost is reduced; when the identification code is damaged or polluted, the identification code can be acquired again in other modes, such as picture transmission, fax printing and the like, so that the problem that information cannot be acquired again after hardware is damaged is avoided, and the fault tolerance rate is high. Through first identification code scanner at first high scanning assay table identification code, at second high scanning reagent card identification code, different highly independently separately mutually noninterfere can improve the success rate to identification code scanning to improve the efficiency of scanning.
In one embodiment, acquiring reaction data corresponding to the detection item includes: acquiring a fluorescence signal; the fluorescence signal is generated by the reaction of the sample and the reagent in the reagent card under the excitation of the exciting light; the fluorescence signal is converted into reaction data.
In one embodiment, obtaining the second information comprises: scanning the identification code of the sample to be detected through a second identification code scanner to obtain second information; the second information includes detection item information of the sample to be detected.
In one embodiment, the second identification code scanner is a handheld identification code scanner.
In one embodiment, a sample testing device, comprising: the identification code scanning module is used for scanning the identification code of the assay table at a first height to obtain first information, and scanning the identification code of the reagent card at a second height to obtain second information; the reaction data acquisition module is used for acquiring reaction data corresponding to the detection items; the second information acquisition module is used for acquiring second information, and the second information comprises detection item information of the sample to be detected; and the calculation module is used for calculating the reaction data based on the first information, the second information and the third information to obtain a detection result.
As shown in fig. 12, 1200 is another sample testing device, and the sample testing device 1200 includes a part of an internal structure 1100, and a first identification code scanner 1202 is provided on the part of the internal structure 1100.
In one embodiment, the identification code scanning module is a first identification code scanner, and the first identification code scanner is built in the sample detection device.
In one embodiment, the detection device is further provided with a first scanning channel and a second scanning channel.
The second scanning channel is located at a second height and comprises a clamping groove, the clamping groove is used for placing a reagent card, the clamping groove and the reagent card placed on the clamping groove move to the scanning direction of the first identification code scanner, and the first identification code scanner scans the identification code on the reagent card at the second height.
The card slot can be pushed by a motor, and the reagent card placed on the card slot is moved to the scanning direction of the first identification code scanner.
As shown in fig. 13, 1302 is a card slot, 1304 is a reagent card, and a reagent card identification code is provided on the reagent card 1304. The reagent card 1304 is moved to the scanning direction of the first identification code scanner 1102 through the card slot 1302, and the first identification code scanner 1102 scans the reagent card identification code at the second height, so that the reagent card identification code can be scanned, and the third information can be obtained.
The first scanning channel is located at a first height, the assay table identification code is placed in the scanning direction of the first identification code scanner through the first scanning channel, and the first identification code scanner scans the identification code on the reagent card at a second height.
In one embodiment, the second scanning channel is located above the first scanning channel.
In one embodiment, the detection apparatus further includes a second identification code scanner, which is externally disposed on the sample detection apparatus and used for scanning the identification code of the sample to be detected.
In one embodiment, the first information is obtained by scanning the checklist identification code 1404 with the identification code scanner 1402; step 1420 is executed to analyze the first information, and the calculation parameter 1426 in the first information may be obtained through the first information management module 1422. Scanning the reagent card identification code 1406 by the identification code scanner 1402 to obtain third information; step 1418 is executed, the third information is analyzed, and the calculation parameter 1426 in the first information may be acquired through the first information management module 1422. The identification code scanner 1402 scans the identification code 1408 of the sample to be tested, and second information 1412 in the hospital server system 1410 can be queried according to the identification code 1408 of the sample to be tested, wherein the second information 1412 can include patient information and information of a patient test item, and a reagent test item 1416 required to be performed can be obtained through the patient information management module 1414; step 1418 may be executed according to the reagent detection items required to be performed, the third information is analyzed, and the calculation parameter 1426 in the first information may be acquired by the first information management module 1422. Reaction data 1430 is acquired, the reaction data 1430 being converted from a fluorescence signal generated by the reaction of the sample to be tested with the reagent in the reagent card and excited by the excitation light. The detection result 1432 can be obtained by calculating the calculation parameter 1426 and the reaction data 1430 through the instrument calculation module 1428.
It should be understood that, although the steps in the flowcharts of fig. 1 and 10 are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and described, and may be performed in other orders, unless explicitly stated otherwise. Moreover, at least some of the steps in fig. 1 and 10 may include multiple sub-steps or multiple stages that are not necessarily performed at the same time, but may be performed at different times, and the order of performing the sub-steps or stages is not necessarily sequential, but may be performed alternately or alternately with other steps or at least some of the sub-steps or stages of other steps.
For the specific definition of the sample detection device, reference may be made to the above definition of the sample detection method, which is not repeated herein. The modules in the sample detection device can be implemented in whole or in part by software, hardware and a combination thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.
In one embodiment, a computer device is provided, which may be a terminal, and its internal structure diagram may be as shown in fig. 15. The computer device includes a processor, a memory, a network interface, a display screen, and an input device connected by a system bus. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device comprises a nonvolatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of an operating system and computer programs in the non-volatile storage medium. The network interface of the computer device is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement a method of sample detection. The display screen of the computer equipment can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer equipment can be a touch layer covered on the display screen, a key, a track ball or a touch pad arranged on the shell of the computer equipment, an external keyboard, a touch pad or a mouse and the like.
Those skilled in the art will appreciate that the architecture shown in fig. 15 is merely a block diagram of some of the structures associated with the disclosed aspects and is not intended to limit the computing devices to which the disclosed aspects apply, as particular computing devices may include more or less components than those shown, or may combine certain components, or have a different arrangement of components.
It will be understood by those skilled in the art that all or part of the processes of the methods of the embodiments described above can be implemented by hardware related to instructions of a computer program, which can be stored in a non-volatile computer-readable storage medium, and when executed, the computer program can include the processes of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in the embodiments provided herein may include non-volatile and/or volatile memory, among others. Non-volatile memory can include read-only memory (ROM), Programmable ROM (PROM), Electrically Programmable ROM (EPROM), Electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), Dynamic RAM (DRAM), Synchronous DRAM (SDRAM), Double Data Rate SDRAM (DDRSDRAM), Enhanced SDRAM (ESDRAM), Synchronous Link DRAM (SLDRAM), Rambus Direct RAM (RDRAM), direct bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM).
The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above examples only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (19)
1. A method of sample detection, the method comprising:
providing a test table identification code, and scanning the test table identification code through an identification code scanner to obtain first information; the first information includes main scaling curve information of the detection item; providing a sample tube to be detected, wherein a sample identification code to be detected is arranged on the sample tube to be detected, and scanning the sample identification code to be detected through the identification code scanner to obtain second information, wherein the second information comprises detection item information of a sample to be detected;
providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and third information is obtained by scanning the reagent card identification code and comprises the detection item information; adding a sample to be detected in the sample tube to be detected to the reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data corresponding to the detection item;
and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected.
2. The method of claim 1, wherein the identification code scanner is a two-dimensional code scanner.
3. The method of claim 1, wherein the verification table identifier is a two-dimensional code; the reagent card identification code is a two-dimensional code.
4. The method according to claim 2 or 3, wherein the obtaining of the third information by scanning the reagent card identification code comprises:
and scanning the reagent card identification code through the two-dimensional code scanner to acquire third information.
5. The method according to any one of claims 1 to 3, wherein the acquiring reaction data corresponding to the detection item includes:
acquiring a fluorescence signal; the fluorescence signal is generated by the reaction of a sample to be detected and a reagent in the reagent card under the excitation of exciting light;
converting the fluorescence signal into reaction data.
6. A sample testing device, comprising:
the identification code scanning module is used for scanning the identification code of the assay table, the sample identification code and the reagent card identification code to acquire first information, second information and third information;
the reaction data acquisition module is used for generating a fluorescence signal by reacting a sample with a reagent in the reagent card and converting the fluorescence signal into reaction data;
and the calculation module is used for calculating the reaction data based on the first information, the second information and the third information to obtain a detection result.
7. The sample testing device of claim 6, wherein the identification code scanning module is an identification code scanner, and wherein the identification code scanner is built into the sample testing device.
8. The apparatus according to claim 6, further comprising a transparent barrier disposed in a scanning direction of the ID scanner.
9. A method of sample detection, the method comprising:
providing an identification code of the assay table, and scanning the identification code of the assay table at a first height through a first identification code scanner to obtain first information; the first information comprises main calibration curve information of the detection items, and the first identification code scanner is a two-dimensional code scanner;
providing a sample tube to be tested, and acquiring second information; the second information comprises detection item information of the sample to be detected;
providing a reagent card, wherein a reagent card identification code is arranged on the reagent card, and the reagent card identification code is scanned at a second height through the first identification code scanner to obtain third information, wherein the third information comprises the detection item information;
adding a sample to be detected in the sample tube to be detected to the reagent card, and reacting the sample to be detected with the reagent in the reagent card to obtain reaction data of the detection item;
and calculating the reaction data based on the first information, the second information and the third information to obtain the detection result of the sample to be detected.
10. The method for detecting a sample according to claim 9, wherein the obtaining the second information includes:
scanning the identification code of the sample to be detected through a second identification code scanner to obtain second information; the second information includes detection item information of the sample to be detected.
11. The sample detection method of claim 10, wherein the second barcode scanner is a handheld barcode scanner.
12. The method according to any one of claims 9 to 11, wherein the obtaining of the reaction data corresponding to the detection item includes:
acquiring a fluorescence signal; the fluorescence signal is generated by the reaction of the sample and the reagent in the reagent card under the excitation of the exciting light;
converting the fluorescence signal into reaction data.
13. A sample testing device, comprising:
the identification code scanning module is used for scanning the identification code of the assay table at a first height to obtain first information, and scanning the identification code of the reagent card at a second height to obtain second information;
the reaction data acquisition module is used for acquiring reaction data corresponding to the detection items;
the second information acquisition module is used for acquiring second information, and the second information comprises detection item information of a sample to be detected;
and the calculation module is used for calculating the reaction data based on the first information, the second information and the third information to obtain a detection result.
14. The sample testing device of claim 13, wherein the identification code scanning module is a first identification code scanner, the first identification code scanner being built into the sample testing device.
15. The sample testing device of claim 13, wherein said testing device is further provided with a first scanning channel and a second scanning channel.
16. The sample testing device of claim 15, wherein said second scanning channel is located at a second elevation and comprises a slot for receiving said reagent card, said slot and said reagent card received therein being moved in a scanning direction of said first identification code scanner, said first identification code scanner scanning a reagent card identification code on a reagent card at a second elevation.
17. The sample testing device of claim 15, wherein said first scanning channel is located at a first elevation, and wherein said assay meter identification code is placed in a scanning direction of said first identification code scanner by said first scanning channel, said first identification code scanner scanning a reagent card identification code on a reagent card at said first elevation.
18. The sample detection device of claim 16 or 17, wherein the second scanning channel is located above the first scanning channel.
19. The apparatus according to claim 12, further comprising a second ID scanner externally disposed on the apparatus for scanning the ID of the sample to be tested.
Priority Applications (3)
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| CN201910893248.8A CN112540062A (en) | 2019-09-20 | 2019-09-20 | Sample detection method and device |
| PCT/CN2020/084953 WO2021051796A1 (en) | 2019-09-20 | 2020-04-15 | Sample testing method, and device |
| AU2020348551A AU2020348551B2 (en) | 2019-09-20 | 2020-04-15 | Sample testing method, and device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910893248.8A CN112540062A (en) | 2019-09-20 | 2019-09-20 | Sample detection method and device |
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| CN112540062A true CN112540062A (en) | 2021-03-23 |
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| CN114169474A (en) * | 2021-12-03 | 2022-03-11 | 四川启睿克科技有限公司 | Sample receiving method, device and equipment and computer readable storage medium |
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| CN113533211B (en) * | 2021-08-20 | 2024-05-07 | 四川新健康成生物股份有限公司 | A barcode recognition device and algorithm for fluorescence analyzer |
| CN114155975B (en) * | 2021-11-26 | 2024-10-22 | 广州金域医学检验中心有限公司 | Sample entry method, device, equipment and storage medium |
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| WO2021051796A1 (en) | 2021-03-25 |
| AU2020348551A1 (en) | 2022-04-07 |
| AU2020348551B2 (en) | 2023-07-13 |
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