CN112206078A

CN112206078A - A metal-rubber-based implant for bone defect

Info

Publication number: CN112206078A
Application number: CN202011209971.9A
Authority: CN
Inventors: 徐杰; 罗骏; 任志英; 林院; 郑益新
Original assignee: FUJIAN PROVINCIAL HOSPITAL
Current assignee: FUJIAN PROVINCIAL HOSPITAL
Priority date: 2020-11-03
Filing date: 2020-11-03
Publication date: 2021-01-12

Abstract

The invention discloses a bone defect implant based on metal rubber, which comprises an osteogenic body, a support body, a fixing mandrel and a connecting mechanism, wherein the support body is arranged in the osteogenic body, the fixing mandrel is arranged in the support body, and two ends of the fixing mandrel are connected with a first fixing end support and a second fixing end support through the connecting mechanism. Compared with the traditional long-stem bone defect implant, the metal rubber bone defect implant not only has good mechanical property, but also has certain porosity and is beneficial to bone tissue growth, the bone implant for fracture or bone defect is provided, the osteogenesis activity effect is increased, and the load bearing and bone growth are facilitated, the metal rubber bone defect implant is an implant made of titanium alloy wires through certain procedures, the biological property is stable, two fixed ends of the metal rubber bone defect implant are of a filling bracket structure, and the problem that a bone defect repair bracket slides after being implanted into the surface of a broken end of the bone defect in the prior art can be effectively solved.

Description

Bone defect implant based on metal rubber

Technical Field

The invention relates to the field of bone defect implants, in particular to a metal rubber-based bone defect implant.

Background

Bone defects after bone tumor resection, nonunion and defects after fracture of long dry bones of limbs and the like are common diseases in clinic. How to repair a large bone joint caused by the resection of bone tumor is a big problem troubling orthopedics. Although bone defects can be repaired by a variety of means (e.g., bone graft fusion, artificial prostheses, and traditional allograft bone joint transplantation), various methods have both advantages and disadvantages. At present, frozen allogeneic bone joint transplantation is adopted clinically, but the bone connection of the transplantation of a large section of allogeneic bone joint needs a quite long time to heal, and part of patients do not heal, so that complications such as bone nonunion, delayed healing of bones, allogeneic bone fracture and the like are caused.

Bone nonunion and defect after fracture of long and dry bones of limbs are usually transplanted by using bone valves, autologous bones, artificial bones and the like at present, but a large number of experiments and clinics prove that the defects of insufficient biomechanical support, bone absorption and the like exist in simple bone transplantation, and the main defects of the artificial synthetic bone clinically used at present are that the mechanical strength is insufficient, the requirement of a load bearing area can not be well met, and the osteogenic activity is poor. It is therefore desirable to have a bone implant that can provide biomechanical support.

Existing bone defect treatments generally involve implanting a repair scaffold at the bone defect, through which the growth and repair of bone tissue is guided. However, the conventional bone defect repair scaffold is generally combined on the surfaces of the broken ends of bone defects at two sides, so that the repair scaffold is easy to slide, and therefore, the neovessels and tissues are ruptured, and further serious inflammation and even osteonecrosis are caused. In addition, in the field of basic research of orthopedics, a large number of in vivo experiments prove that after bone defects occur, the cortex at the two broken ends cannot be directly osteogenized, and the new bone tissues mainly come from periosteum and endosteum. Wherein, the osteogenic ability of the endosteum is strongest, and a large amount of trabeculae can be formed in a short time to seal the medullary cavity and prevent the bone marrow from flowing outwards. However, this natural phenomenon may be detrimental to the repair of bone tissue engineering: (1) after the traditional bone defect repairing scaffold is implanted into the surfaces of the bone defect broken ends on the two sides, a certain gap is reserved between the two ends of the repairing scaffold and a large amount of intimal osteogenesis, and the two ends of the repairing scaffold cannot be directly connected with each other, so that the intimal osteogenesis is wasted; (2) intimal osteogenesis closes the medullary cavity, so that osteogenic associated cells and factors in the medullary cavity cannot effectively penetrate the scaffold material. Therefore, the introduction of intimal osteogenesis and bone marrow factors is of great significance for tissue engineering repair of bone defects.

The treatment of organ defects caused by various wounds, infections and diseases is still one of the medical problems, and the development in the field of tissue engineering brings new hopes for constructing a 'safe and effective tissue and organ transplantation substitute', particularly 3D printing technology, and personalized scaffold materials can be designed according to the position and the shape of defects.

Disclosure of Invention

The present invention is directed to solving the above problems by providing a metal rubber-based bone defect implant.

The invention realizes the purpose through the following technical scheme:

the utility model provides a defective implant of bone based on metal rubber, includes bone body, supporter, fixed dabber, coupling mechanism, the internal portion of bone body is provided with the supporter, the supporter is inside to be provided with fixed dabber, fixed dabber both ends are all passed through coupling mechanism connects stiff end support one and stiff end support two, the supporter with be provided with the through-hole between the bone body, coupling mechanism includes set screw, retaining ring, screw hole, retaining ring sets up stiff end support one two sides of stiff end support, set screw passes retaining ring connects fixed dabber, set screw with be provided with between the fixed dabber the screw hole.

Preferably: the osteogenesis body is wrapped outside the support body, and the osteogenesis body and the support body are both of cylindrical structures.

So set up, utilize bilayer structure to guarantee stability and variety.

Preferably: the density of the support body is greater than that of the bone forming body, the bone forming body is made of metal rubber with large pores, and the support body is made of metal rubber with small pores.

According to the arrangement, the support body is made of metal rubber with large porosity, the structural density is high, the overall comparative strength is high, and the load supporting effect is achieved; the external bone forming body is made of metal rubber with high porosity, and certain pores are distributed in the external bone forming body to play a good buffering role.

Preferably: the first fixed end support and the second fixed end support are evenly provided with small holes.

According to the arrangement, the first fixed end support and the second fixed end support are used for connecting external bones.

Compared with the prior art, the invention has the following beneficial effects:

1. compared with the traditional long dry bone defect implant, the metal rubber bone defect implant not only has good mechanical property, but also has certain porosity, thereby being beneficial to the growth of bone tissues;

2. to provide a bone implant for bone fracture or bone defect which increases osteogenic activity effect and facilitates weight bearing and bone ingrowth;

3. the metal rubber bone defect implant is an implant made of titanium alloy wires through a certain process, has stable biological performance, and can effectively solve the problem that the bone defect repair bracket in the prior art slides after being implanted into the surface of the bone defect broken end because two fixed ends of the metal rubber bone defect implant are of a filling bracket structure.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

FIG. 1 is a schematic structural view of a metal rubber-based bone defect implant according to the present invention;

FIG. 2 is a schematic view of the internal structure of a metal rubber-based bone defect implant according to the present invention;

fig. 3 is a schematic structural view of a connection mechanism of a metal rubber-based bone defect implant according to the present invention.

The reference numerals are explained below:

1. a shaft; 2. a support body; 3. a fixed end bracket I; 4. a fixed end bracket II; 5. fixing the mandrel; 6. a through hole; 7. a connecting mechanism; 701. a set screw; 702. fixing a retainer ring; 703. a threaded bore.

Detailed Description

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.

The invention will be further described with reference to the accompanying drawings in which:

example 1

As shown in fig. 1-3, a bone defect implant based on metal rubber comprises an osteogenesis body 1, a support body 2, a fixing mandrel 5 and a connecting mechanism 7, wherein the support body 2 is arranged inside the osteogenesis body 1, the fixing mandrel 5 is arranged inside the support body 2, two ends of the fixing mandrel 5 are connected with a first fixing end support 3 and a second fixing end support 4 through the connecting mechanism 7, a through hole 6 is arranged between the support body 2 and the osteogenesis body 1, the connecting mechanism 7 comprises a fixing screw 701, a fixing retainer ring 702 and a threaded hole 703, the fixing retainer ring 702 is arranged on one side of the first fixing end support 3 and the second fixing end support 4, the fixing screw 701 penetrates through the fixing retainer ring 702 to be connected with the fixing mandrel 5, and the threaded hole 703 is arranged between the fixing screw 701.

Preferably: the osteogenesis body 1 is wrapped outside the support body 2, and the osteogenesis body 1 and the support body 2 are both in cylindrical structures.

So set up, utilize bilayer structure to guarantee stability and variety.

Preferably: the density of the support body 2 is greater than that of the bone forming body 1, the bone forming body 1 is made of metal rubber with large pores, and the support body 2 is made of metal rubber with small pores.

Due to the arrangement, the support body 2 is made of metal rubber with large porosity, the structural density is high, the overall comparative strength is high, and the load bearing support effect is achieved; the outer bone forming body 1 is made of metal rubber with large porosity, and certain pores are distributed in the inner bone forming body to play a good buffering role.

Preferably: the first fixed end support 3 and the second fixed end support 4 are evenly provided with small holes.

So set up, utilize stiff end support one 3, stiff end support two 4 to play the effect of connecting outside skeleton.

The working principle is as follows: a second metal rubber bone defect implant fixed end support 4 and a fixing mandrel 5 are of an integral structure, a through hole 6 is formed in a support body 2 and fixed on the fixing mandrel 5, a through hole is also formed in an osteogenesis body 1 and is embedded outside the support body 2, the end face of the second metal rubber bone defect implant fixed end support 4 is in contact with the end faces of the osteogenesis body 1 and the support body 2, the axial movement of the osteogenesis body 1 and the support body 2 is limited by using a fixing screw 701 and a fixing retaining ring 702 to be matched with a threaded hole 703 at the shaft end of the fixing mandrel 5, when the metal rubber bone defect implant is placed in a medullary cavity of the broken ends at two ends of a bone defect position, a rivet-like embedded structure is formed, the two ends of an autogenous bone are fixed through.

The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed.

Claims

1. A bone defect implant based on metal rubber is characterized in that: comprises an adult bone body (1), a support body (2), a fixed mandrel (5) and a connecting mechanism (7), the support body (2) is arranged in the adult bone body (1), the fixed mandrel (5) is arranged in the support body (2), both ends of the fixed mandrel (5) are connected with a first fixed end bracket (3) and a second fixed end bracket (4) through the connecting mechanism (7), a through hole (6) is arranged between the support body (2) and the bone forming body (1), the connecting mechanism (7) comprises a fixing screw (701), a fixing retainer ring (702) and a threaded hole (703), the fixed retainer ring (702) is arranged at one side of the first fixed end bracket (3) and the second fixed end bracket (4), the fixing screw (701) penetrates through the fixing retainer ring (702) to be connected with the fixing mandrel (5), the threaded hole (703) is formed between the fixing screw (701) and the fixing mandrel (5).

2. A metal rubber based bone defect implant according to claim 1, wherein: the osteogenesis body (1) is wrapped outside the support body (2), and both the osteogenesis body (1) and the support body (2) are of cylindrical structures.

3. A metal rubber based bone defect implant according to claim 1, wherein: the density of the support body (2) is greater than that of the osteogenic body (1), the osteogenic body (1) is made of metal rubber with large pores, and the support body (2) is made of metal rubber with small pores.

4. A metal rubber based bone defect implant according to claim 1, wherein: the fixed end support I (3) and the fixed end support II (4) are evenly provided with small holes.