CN112169066A - Continuous release drug delivery indwelling tube with controller - Google Patents
Continuous release drug delivery indwelling tube with controller Download PDFInfo
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- CN112169066A CN112169066A CN202011183332.XA CN202011183332A CN112169066A CN 112169066 A CN112169066 A CN 112169066A CN 202011183332 A CN202011183332 A CN 202011183332A CN 112169066 A CN112169066 A CN 112169066A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16877—Adjusting flow; Devices for setting a flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
本发明提供一种具有控制器的连续缓释给药留置管，包括具有中空管腔的缓释管体、注药管、储药囊、控制器，所述缓释管体具有第一管壁以及处于所述第一管壁外侧的第二管壁，其中第二管壁为缓释膜，所述第一管壁与所述第二管壁之间形成缓释腔，所述缓释腔通过所述注药管与所述储药囊连通，所述储药囊处于控制器内，所述控制器被配置为能够调整所述储药囊以预设注药压力或者注药速度将所述储药囊中的药液迫出，药液进入所述注药管并经由所述第二管壁渗出至其外侧。本发明的具有控制器的连续缓释给药留置管，避免对需多次给药的患者的反复穿刺，无需对给药范围广的患者多点穿刺，降低病患医疗过程中的痛苦，改善病患的就医体验。
The invention provides a continuous sustained-release drug indwelling tube with a controller, comprising a sustained-release tube body with a hollow lumen, a drug injection tube, a drug storage bag, and a controller, wherein the sustained-release tube body has a first tube wall And the second tube wall outside the first tube wall, wherein the second tube wall is a slow-release film, a slow-release cavity is formed between the first tube wall and the second tube wall, and the slow-release cavity is The medicine injection tube communicates with the medicine storage bag, and the medicine storage bag is located in the controller, and the controller is configured to be able to adjust the medicine storage bag to inject all the medicines at a preset medicine injection pressure or speed. The medicinal liquid in the medicine storage bag is forced out, and the medicinal liquid enters the medicine injection tube and seeps out to the outside of the medicine injection tube through the second tube wall. The continuous sustained-release drug delivery indwelling tube with a controller of the present invention avoids repeated puncturing of patients who need multiple drug administrations, and does not require multi-point puncture for patients with a wide range of drug administration, reduces the pain of patients in the medical treatment process, and improves the patient experience.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a continuous slow-release drug administration indwelling tube with a controller.
Background
For many patients with sports injury, a local nerve blocking method is often needed to relieve pain and eliminate inflammation, and for some patients with substantial tumors, a tumor body injection method can be used to kill tumor cells. However, the prior art only can carry out single administration, and patients who need to carry out multiple administrations have to puncture repeatedly, which undoubtedly increases the pain of the patients; in addition, during administration, the medicine only can be intensively effused from the outlet of the administration tube, and the medicine is often gathered at the outlet and can not be diffused to a sufficiently far area, so that for some patients needing wide administration range, the medicine has to be administered by multi-point puncture, and for the patients adopting percutaneous puncture area continuous administration treatment (such as analgesia, chemotherapy and the like), the invention is provided on the basis that the long-time uniform local administration can not be realized in a good mode.
Disclosure of Invention
Therefore, the technical problem to be solved by the present invention is to provide a continuous sustained release drug administration indwelling tube with a controller, which avoids repeated puncturing of a patient who needs multiple drug administrations, does not need to puncture the patient at multiple points with a wide drug administration range, reduces pain of the patient in a medical treatment process, and improves medical experience of the patient.
In order to solve the above problems, the present invention provides a continuous sustained-release drug delivery indwelling tube with a controller, including a sustained-release tube body having a hollow tube cavity, a drug injection tube, a drug storage bag, and a controller, wherein the sustained-release tube body has a first tube wall and a second tube wall located outside the first tube wall, the second tube wall is a sustained-release membrane, a sustained-release cavity is formed between the first tube wall and the second tube wall, the sustained-release cavity is communicated with the drug storage bag through the drug injection tube, the drug storage bag is located in the controller, the controller is configured to adjust the drug storage bag to force out a drug solution in the drug storage bag at a preset drug injection pressure or drug injection speed, and the drug solution enters the drug injection tube and seeps out to the outside of the drug injection tube through the second tube wall.
Preferably, the slow release membrane is made of medical hydrophilic and hydrophobic nano composite materials.
Preferably, the medical hydrophilic and hydrophobic nanocomposite comprises one of a fluoropolymer and a polyurethane.
Preferably, the continuous slow release drug administration indwelling tube with the controller further comprises a puncture inner core capable of passing through the hollow lumen.
Preferably, the first end of the plunger has a syringe interface.
Preferably, the drug injection tube is communicated with the drug storage bag through a connecting tube, and the connecting tube is a flexible tube.
Preferably, the drug injection tube and the slow release tube body are connected into a whole.
Preferably, a display screen is arranged on the controller; and/or the controller is provided with an adjusting button.
Preferably, the controller is also internally provided with an induction element, the induction element is used for detecting the inner cavity pressure of the medicine storage bag, and an obtained inner cavity pressure signal is processed by a core operation element in the controller and then is transmitted and displayed on the display; and/or the acquired inner cavity pressure signal is operated by a core operation element in the controller to acquire the residual medicine quantity in the medicine storage bag, and the acquired residual medicine quantity is transmitted and displayed on the display.
Preferably, the controller further comprises an alarm device for sending an alarm signal when the pressure of the inner cavity of the medicine storage bag acquired by the sensing element exceeds a preset interval.
According to the continuous slow-release drug delivery indwelling tube with the controller, due to the design of the drug storage bag and the slow-release cavity, medical staff can puncture the indwelling catheter at multiple points and puncture repeatedly in the prior art only once, liquid medicine in the drug storage bag, the drug injection tube and the slow-release cavity can slowly permeate and seep to indwelling target tissues of a patient through the second tube wall, the tube length of the slow-release cavity can cover a large drug delivery area, and the patient with a wide drug delivery range does not need to puncture the drug at multiple points and puncture repeatedly, so that pain in the medical treatment process of the patient is reduced, medical experience of the patient is improved, in addition, adjustment and control of drug injection pressure or drug injection speed of the liquid medicine in the drug storage bag are realized through the controller in the technical scheme, and thus drug delivery dosage can be accurately controlled.
Drawings
FIG. 1 is a schematic structural view of a continuous sustained-release administration indwelling tube having a controller according to an embodiment of the present invention.
The reference numerals are represented as:
1. a slow release tube body; 11. a first tube wall; 12. a second tube wall; 13. a sustained release chamber; 2. a medicine injection tube; 21. a connecting pipe; 3. a medicine storage bag; 4. puncturing the inner core; 41. an injector interface; 5. a controller; 51. a display screen; 52. an adjusting knob.
Detailed Description
Referring to fig. 1, according to an embodiment of the present invention, there is provided a continuous sustained-release drug delivery indwelling tube with a controller, including a sustained-release tube body 1 having a hollow tube cavity, a drug injection tube 2, and a drug storage bag 3, where the sustained-release tube body 1 has a first tube wall 11 and a second tube wall 12 located outside the first tube wall 11, where the second tube wall 12 is a sustained-release membrane, a sustained-release cavity 13 is formed between the first tube wall 11 and the second tube wall 12, the sustained-release cavity 13 is communicated with the drug storage bag 3 through the drug injection tube 2, the drug storage bag 3 is located in the controller 5, and the controller 5 is configured to be capable of adjusting the drug storage bag 3 to force out a drug solution in the drug storage bag 3 at a preset drug injection pressure or drug injection speed, and the drug solution enters the drug injection tube 2 and seeps out of the drug injection tube through the second tube wall 12 to the outside thereof. In the technical scheme, through medicine storage bag 3 with the design of slowly-releasing chamber 13 makes medical personnel can only puncture once just can realize the purpose of multiple spot puncture among the prior art, puncture repeatedly, is in medicine storage bag 3, injection pipe 2 and slowly-releasing chamber 13 in the liquid medicine can pass through the slow infiltration of second pipe wall 12 oozes to the target tissue of keeping somewhere of disease, just the pipe length of slowly-releasing chamber 13 can cover great administration area, need not to puncture to the wide patient multiple spot of scope of dosing, puncture repeatedly to the misery in disease medical treatment process has been reduced, has improved the experience of seeking medical advice of disease, in addition, passes through in this technical scheme controller 5 realize right the injection pressure or the adjustment control of injection speed of liquid among the medicine storage bag 3, thereby can the accurate control dose of dosing. It will be appreciated that the drug storage capsule 3 is provided with a drug injection port to allow for replenishment of the drug storage capsule 3 with drug solution. The first tube wall 11 is made of a non-permeable membrane, and prevents the liquid medicine from permeating into the hollow cavity of the sustained-release tube body 1 through the non-permeable membrane.
Preferably, the medicine storage bag 3 is made of an elastic material, and specifically, for example, one of silica gel, rubber, latex or nylon can be used, wherein the formable wall thickness of the silica gel is 0.2-0.4mm, the shore softness is 30, the medicine storage bag can be manufactured by injection molding or bonding technology, the elasticity is good, the product performance is stable, the medicine storage bag is transparent, and the medicine storage bag can be beneficial for an operator to observe the liquid medicine condition in the bag; the formable wall thickness of the rubber is 0.5-0.8mm, the Shore softness is 40, the formable wall can be manufactured by adopting an injection molding or bonding process, the formable wall has general elasticity, the appearance is rough, the hardness is high, the formable wall is mostly white, and the liquid medicine condition in the capsule can not be observed; the formable wall thickness of the latex is 0.2-1mm, the Shore softness is 20-30, the formable latex can be manufactured by adopting an injection molding or bonding process, the formable latex has moderate elasticity, the appearance is not fine and smooth enough, the formable latex is semitransparent, and the forming effect is not good; the wall thickness of the formable nylon is 0.2-0.6mm, the formable nylon can be manufactured by adopting a bonding process, the formable nylon has poor elasticity and is semitransparent, and therefore, the formable nylon is best, and the medicine storage bag 3 is made of silica gel.
As a specific embodiment, it is preferable that the controller 5 is provided with a display screen 51 for displaying the current administration speed or administration pressure, so as to facilitate the medical staff to clearly determine the administration condition during the infusion process; meanwhile, the controller 5 is provided with an adjusting button 52, and the adjusting button 52 is used for adjusting the administration speed or the administration pressure, such as increasing the administration speed or the administration pressure or decreasing the administration speed or the administration pressure. Further, an induction element is arranged in the controller 5, the induction element is used for detecting the inner cavity pressure of the medicine storage bag 3, and an obtained inner cavity pressure signal is processed by a core operation element in the controller 3 and then is transmitted and displayed on the display 51; and/or the acquired inner cavity pressure signal is operated by a core operation element in the controller 3 to acquire the residual medicine quantity in the medicine storage bag 3, and the acquired residual medicine quantity is transmitted and displayed on the display 51.
As a better implementation manner, the controller 5 further includes an alarm device, and is configured to send an alarm signal when the pressure of the inner cavity of the medicine storage bag 3 obtained by the sensing element exceeds a preset interval (that is, when the pressure of the inner cavity is lower than a preset low-pressure threshold or higher than a preset high-pressure threshold), where the alarm signal includes a flashing indicator light, a buzzer sound, or a text prompt, so as to prompt a medical worker to adjust the administration pressure in time.
The slow release membrane is preferably made of medical hydrophilic and hydrophobic nano composite materials, specifically, the medical hydrophilic and hydrophobic nano composite materials comprise one of fluorine-containing macromolecules and polyurethane, and the aperture of a permeation hole on the slow release membrane is 1-100 nm.
Further, the continuous slow-release administration indwelling tube with the controller further comprises a puncture inner core 4, wherein the puncture inner core 4 can penetrate through the hollow tube cavity, namely the puncture inner core 4 can be pulled out of the hollow tube cavity or inserted into the hollow tube cavity, so that the percutaneous puncture process of the indwelling tube is facilitated. Preferably, the drug injection tube 2 and the sustained-release tube body 1 are connected into a whole to prevent the drug solution from leaking at the joint. The interface between the drug injection tube 2 and the sustained-release tube body 1 should be positioned in the target indwelling tissue when the indwelling tube is applied to prevent the drug solution from being externally infiltrated to the outside of the skin of the human body when sustained-release drug delivery is performed.
The puncture inner core 4 is made of hard medical material, and a syringe interface 41 is further arranged at the first end (namely, the end positioned outside the human body) of the puncture inner core so as to be connected with a syringe to directly inject liquid medicine through the puncture inner core.
Preferably, the drug injection tube 2 is communicated with the drug storage bag 3 through a connecting tube 21, the connecting tube 21 is a flexible tube, and the connecting tube 21 has flexibility, which facilitates the selection of the drug administration angle of the medical staff when the drug is administered into the drug storage bag 3.
As a more preferable embodiment, the periphery of the sustained release tube body 1 can be optionally sleeved with a sustained release positioning film sleeve (not shown in the figure), the sustained release positioning film sleeve is provided with a through hole, the sustained release positioning film sleeve outside the through hole can prevent the liquid medicine in the sustained release tube body 1 from seeping out, and the through hole can allow the liquid medicine in the sustained release tube body 1 to seep out, so that the liquid medicine seeping out in the sustained release tube body 1 can be positioned, and the sustained release tube body is suitable for the situation that the sustained drug delivery is required for some point-like focuses.
It is readily understood by a person skilled in the art that the advantageous ways described above can be freely combined, superimposed without conflict.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention. The above is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the technical principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention.
Claims (10)
1. A continuous slow-release drug delivery indwelling tube with a controller is characterized by comprising a slow-release tube body (1) with a hollow tube cavity, a drug injection tube (2), a drug storage bag (3) and a controller (5), the slow release tube body (1) is provided with a first tube wall (11) and a second tube wall (12) positioned outside the first tube wall (11), wherein the second tube wall (12) is a slow release film, a slow release cavity (13) is formed between the first tube wall (11) and the second tube wall (12), the slow release cavity (13) is communicated with the medicine storage bag (3) through the medicine injection tube (2), store up the anther sac (3) and be in controller (5), controller (5) are configured as and can adjust store up anther sac (3) will with preset injection pressure or injection speed the liquid medicine in storing up anther sac (3) is forced out, the liquid medicine gets into injection pipe (2) and via second pipe wall (12) oozes to its outside.
2. The continuous sustained-release drug delivery indwelling tube according to claim 1, wherein the sustained-release membrane is made of medical hydrophilic and hydrophobic nano composite material.
3. The indwelling catheter for continuous sustained release drug delivery with a controller according to claim 2, wherein the medical hydrophilic and hydrophobic nanocomposite comprises one of fluoropolymer and polyurethane.
4. The continuous slow release drug delivery indwelling tube with controller according to claim 1, further comprising an inner piercing core (4), the inner piercing core (4) being capable of passing through the hollow lumen.
5. The continuous slow release drug delivery indwelling tube with a controller according to claim 4, wherein the first end of the puncture inner core (4) has a syringe port (41).
6. The continuous sustained-release drug delivery indwelling tube with the controller according to claim 1, wherein the drug injection tube (2) is communicated with the drug storage pouch (3) through a connection tube (21), the connection tube (21) being a flexible tube.
7. The continuous sustained-release drug delivery indwelling tube with the controller according to claim 6, wherein the drug injection tube (2) is integrally connected to the sustained-release tube body (1).
8. The continuous slow-release drug administration indwelling tube with a controller according to any one of claims 1 to 7, wherein a display screen (51) is provided on the controller (5); and/or the controller (5) is provided with an adjusting button (52).
9. The indwelling tube for continuous slow-release drug delivery with a controller according to claim 8, wherein the controller (5) is further provided with a sensing element for detecting the pressure of the inner cavity of the drug storage bag (3), and the obtained inner cavity pressure signal is processed by a core operation element inside the controller (3) and then transmitted and displayed on the display (51); and/or the acquired inner cavity pressure signal is operated by a core operation element in the controller (3) to acquire the residual medicine quantity in the medicine storage bag (3), and the acquired residual medicine quantity is transmitted and displayed on the display (51).
10. The indwelling catheter for continuous slow release drug delivery with a controller according to claim 9, wherein the controller (5) further comprises an alarm device for emitting an alarm signal when the pressure of the lumen of the drug reservoir (3) obtained by the sensing element exceeds a preset interval.
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| CN202011183332.XA CN112169066B (en) | 2020-10-29 | 2020-10-29 | Continuous extended release drug delivery indwelling tube with controller |
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| CN202011183332.XA CN112169066B (en) | 2020-10-29 | 2020-10-29 | Continuous extended release drug delivery indwelling tube with controller |
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| CN112169066B CN112169066B (en) | 2023-05-12 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112915315A (en) * | 2021-03-19 | 2021-06-08 | 荆文斌 | Anti-extravasation chemotherapy administration device for medical oncology |
| CN119345525A (en) * | 2024-12-24 | 2025-01-24 | 内蒙古医科大学附属医院(内蒙古自治区心血管研究所) | A chemotherapy infusion device for tumor patients |
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