CN111870825B - Precise Field-by-Field Positioning Method for Radiation Therapy Based on Virtual Intelligent Medical Platform - Google Patents

Abstract

The application relates to the field of medical treatment, in particular to a radiation therapy accurate field-by-field positioning method based on a virtual intelligent medical platform, which improves positioning accuracy and reduces additional radiation. Pasting a marker on the body surface of a patient; then making a treatment plan, and marking the center coordinates of the markers in a treatment plan system by a physicist, and generating a three-dimensional model according to the treatment plan; according to the automatic identification of the position of the patient by the marker, the position of the irradiation field is determined according to the position of the accelerator, and the three-dimensional hologram of the structures such as skin, a treatment target area, organs endangered and the like can be accurately overlapped on the real patient, can be intuitively displayed in the visual field, and is convenient for observing the position of the structures such as the treatment target area and the like in the patient. The medical staff can observe the superposition condition of the treatment target area and the field outline of the current angle shooting at different positions, intelligently and quantitatively calculate the superposition degree, give out the moving direction and the distance value in real time, and improve the positioning precision. The patient does not need to bear extra radiation dose, and the pain of the patient can be reduced.

Description

Precise Field-by-Field Positioning Method for Radiation Therapy Based on Virtual Intelligent Medical Platform

technical field

The invention relates to the medical field, in particular to a method for precise field-by-field radiotherapy positioning based on a virtual intelligent medical platform, which is mainly used in radiotherapy to improve positioning accuracy and reduce additional radiation.

Background technique

The virtual intelligent medical platform (VI) is a medical platform built on the basis of technologies such as virtual reality, augmented reality, mixed reality and other holographic technologies, artificial intelligence and big data, and is used to assist and guide invasive, minimally invasive, non-invasive clinical diagnosis and The treatment process can be applied to fields including but not limited to surgery, internal medicine, radiotherapy, and interventional medicine.

Malignant tumors are major chronic diseases that seriously endanger human health. Radiotherapy is one of the main methods of tumor treatment, and it is a local treatment method, which can improve the local tumor control rate by increasing the tumor irradiation dose.

The complete radiotherapy process includes radiotherapy decision-making, radiotherapy positioning, treatment target delineation and treatment plan design, treatment room setup, treatment implementation and other steps. The positioning of the treatment room is an important link to ensure the curative effect of precise radiotherapy. If there is a mistake in the positioning, it will cause the lesion to fail to obtain sufficient radiation dose and cause local recurrence. complication. However, even if various auxiliary positioning devices are used and the positioning is strictly in accordance with the operating procedures, the positioning error may still be several millimeters or even larger during the process of the patient receiving fractional treatment. In order to solve the above problems, it is currently necessary to verify the results of the positioning after the positioning is completed in order to reduce the positioning error.

At present, clinical setup verification mainly adopts kV-level X-ray imaging technology or airborne vertebral CT (CBCT) technology. Image-guided technology based on X-ray imaging technology is to determine the position of the patient or lesion (for example, tumor) through single or multiple X-ray fluoroscopy images and 2D-3D (two-dimensional-three-dimensional) image registration of treatment planning CT , adjust the position of the patient by moving the treatment bed before treatment to achieve precise treatment of the tumor. The image-guided technology based on CBCT technology realizes patient positioning before treatment through 3D-3D (three-dimensional-three-dimensional) image registration of CBCT generated online and treatment plan CT.

The disadvantages of the above two methods are:

During the treatment, neither the tumor nor the radiation can be observed intuitively.

During the radiotherapy cycle, patients are exposed to non-therapeutic radiation multiple times, need to bear additional X-ray radiation dose, and the cost of equipment is high.

At the current stage, IGRT regards the patient as a "whole" and corrects it; even if the registration process registers the tumor from the transverse, sagittal, and coronal planes, when the gantry rotates to the angle of irradiation, whether the tumor falls Into the irradiation field, unknown.

Contents of the invention

Aiming at the defects in the prior art, the present invention provides an accurate field-by-field positioning method for radiotherapy based on a virtual intelligent medical platform that improves positioning accuracy and reduces additional radiation.

The technical solution adopted by the present invention is: a method for accurately field-by-field positioning of radiotherapy based on a virtual intelligent medical platform, comprising the following steps:

a. Post markers on accelerators and patients, and perform CT scans on patients;

b. Formulate a treatment plan based on the patient's CT image and generate a three-dimensional model;

c. The holographic glasses identify the markers to obtain positioning information, overlap and register the holographic image of the three-dimensional model with the patient, and overlap and register the irradiation field with the accelerator;

d. Automatically calculate the degree of coincidence, give the value of bed movement, and prepare for radiotherapy.

In order to better realize the present invention, in the step b, the features of the patient's body surface model and the features of the tumor model are generated according to the treatment plan.

In order to better realize the present invention, the marker contains spatial position information.

In order to better realize the present invention, the markers are objects with specific two-dimensional image features.

In order to better realize the present invention, in the step b, judge the patient's condition according to the CT scan image, draw the treatment target area and the organs at risk, and generate a corresponding three-dimensional model.

In order to better realize the present invention, in the step c, the fixing device is first placed, and then the patient is placed in the treatment position according to the doctor's order, and then the holographic image of the treatment target area and the organ at risk is projected to the patient's position, so that the holographic image and the patient Perform overlay registration.

In order to better realize the present invention, when the holographic image and the patient are overlapped, the location can be quickly identified through the marker.

In order to better realize the present invention, in step d, when the holographic image of the treatment target area and the organ at risk coincides with the patient, the irradiation field is projected onto the patient, the position of the treatment target area is verified and the bed shift value is given to ensure The location is accurate and ready for radiotherapy.

The beneficial effects of the present invention are reflected in: the precise field-by-field positioning method for radiotherapy based on the virtual intelligent medical platform of the present invention, firstly post markers on the patient's body surface; then formulate a treatment plan, and the physicist calibrates the markers in the treatment planning system Center coordinates, and generate a 3D model according to the treatment plan; when positioning, automatically identify the position of the patient according to the marker, determine the position of the irradiation field according to the position of the accelerator, cooperate with the mixed reality equipment, 3D holographic images of the skin, treatment target area, endangered organs and other structures It can be accurately superimposed on the real patient, and can be displayed intuitively in the field of vision, making it easy to observe the position of the treatment target area and other structures in the patient's body. Medical workers can observe the coincidence of the treatment target area and the outline of the radiation field at the current angle at different positions, intelligently quantify and calculate the coincidence degree, and give the bed moving direction and distance value in real time to improve the positioning accuracy. Patients do not need to bear additional radiation doses, which can reduce the suffering of patients.

Description of drawings

In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings that need to be used in the description of the specific embodiments or the prior art. Throughout the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, elements or parts are not necessarily drawn in actual scale.

Fig. 1 is a kind of flow chart of the radiotherapy accurate field-by-field positioning method based on the virtual intelligent medical platform of the present invention;

Fig. 2 is a kind of structural representation of the treatment equipment of the radiotherapy accurate field-by-field positioning method based on the virtual intelligent medical platform of the present invention;

In the figure, 1—frame, 2—treatment bed, 3—bottom plate, 4—patient, 6—irradiation field, 7—skin, 8—treatment target area.

Detailed ways

Embodiments of the technical solutions of the present invention will be described in detail below in conjunction with the accompanying drawings. The following examples are only used to illustrate the technical solutions of the present invention more clearly, and therefore are only examples, rather than limiting the protection scope of the present invention.

It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application shall have the usual meanings understood by those skilled in the art to which the present invention belongs.

Example 1:

As shown in Fig. 1 and Fig. 2, the radiotherapy accurate field-by-field positioning method based on the virtual intelligent medical platform of the present invention comprises the following steps:

a. Post markers on the accelerator and patient 4, and perform a CT scan on patient 4;

b. Formulate a treatment plan based on the CT image of patient 4, and generate a three-dimensional model;

c. The holographic glasses identify the markers to obtain positioning information, overlap and register the holographic image of the three-dimensional model with the patient 4, and overlap and register the irradiation field 6 with the accelerator;

d. Automatically calculate the degree of coincidence, give the value of bed movement, and prepare for radiotherapy.

According to the precise field-by-field positioning method for radiotherapy based on the virtual intelligent medical platform of the present invention, firstly, post markers for the patient 4, and take a CT scan for the patient 4; Then, the three-dimensional model is superimposed on the patient 4 through the holographic image, and the position is adjusted to make them overlap; the irradiation field 6 is projected to the affected part of the patient through the holographic image, and the position of the patient 4 is verified to prepare for radiotherapy. In this way, with mixed reality equipment, the 3D holographic images of the skin, treatment target area, organs at risk and other structures can be accurately superimposed on the real patient 4, and can be intuitively displayed in the field of vision, making it easy to observe the position of the treatment target area and other structures in the patient 4 body . With mixed reality equipment, medical workers can observe the coincidence of the treatment target area 8 and the outer contour of the radiation field at the current angle at different positions, intelligently quantify and calculate the coincidence degree, and give the bed moving direction and distance values in real time to improve the positioning accuracy. Patient 4 does not need to bear additional radiation dose, which can reduce the patient's pain and improve the treatment effect.

Example 2:

On the basis of the above embodiments, in order to further better implement the present invention, in the step b, the features of the patient's body surface model and the features of the tumor model are generated according to the treatment plan.

Example 3:

On the basis of the above embodiments, in order to further better implement the present invention, the marker contains spatial position information, so that it can be conveniently and quickly positioned, and it is convenient to correct the deviation. As a preference, the marker has For an object with specific two-dimensional image features, the object with specific two-dimensional image features contains corresponding position information.

Preferably, in the step b, the condition of the patient 4 is determined according to the CT scan image, the treatment target area 8 and the organs at risk are drawn, and a corresponding three-dimensional model is generated.

Example 4:

On the basis of the above-mentioned embodiments, in order to further better implement the present invention, in the step c, first change the base plate 3, then lower the bed, and then lie on the patient 4, then move to the treatment position, and then place the treatment target area 8 and the holographic image of the organ at risk is projected to the position of the patient 4, so that the holographic image and the patient can be overlapped and registered.

Preferably, when the holographic image and the patient are overlapped, the location can be quickly identified through the marker.

Example 5:

On the basis of the above embodiments, in order to further better implement the present invention, in the step d, when the holographic image of the treatment target area 8 and the organ at risk overlaps with the patient 4, the irradiation field 6 is projected onto the patient 4 , verify the position of the treatment target area 8 and give the bed shift value to ensure that the position is accurate, and prepare for radiotherapy. The three-dimensional holographic image can be used to easily fine-tune the position to ensure that the position of radiotherapy is accurate, reduce redundant radiation, and reduce the burden on patients. s damage.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: It is still possible to modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the various embodiments of the present invention. All of them should be covered by the scope of the claims and description of the present invention.

Claims (6)

1. The accurate field-by-field positioning method for radiotherapy based on the virtual intelligent medical platform is characterized by comprising the following steps of:

a. labeling an accelerator and a patient (4), and performing CT scanning on the patient, wherein the label adopts an object with specific two-dimensional image characteristics, and corresponding position information is included in the object with the specific two-dimensional image characteristics;

b. a treatment plan is formulated according to CT images of a patient (4), and a three-dimensional model is generated;

c. the holographic glasses recognize the marker to obtain positioning information, the holographic image of the three-dimensional model is overlapped and registered with the patient (4), and the irradiation field (6) is overlapped and registered with the accelerator;

d. automatically calculating the overlap ratio, giving a moving bed value, and preparing for radiotherapy;

in the step d, after the holographic images of the treatment target area (8) and the organs at risk are overlapped with the patient (4), a medical worker can observe the overlapping condition of the treatment target area and the current angle shooting field outline at different positions, intelligently and quantitatively calculate the overlapping ratio, give out the moving direction and the distance value in real time, and prepare for radiotherapy.

2. The accurate field-by-field positioning method for radiotherapy based on a virtual intelligent medical platform according to claim 1, wherein the method comprises the following steps: in the step b, the body surface model characteristics and the tumor model characteristics of the patient are generated according to the treatment plan.

3. The accurate field-by-field positioning method for radiotherapy based on the virtual intelligent medical platform according to claim 2, wherein the method comprises the following steps: the marker contains spatial position information.

4. The accurate field-by-field positioning method for radiotherapy based on a virtual intelligent medical platform according to claim 1, wherein the method comprises the following steps: in the step b, the illness state of the patient (4) is judged according to the CT scanning image, a treatment target area (8) and organs at risk are drawn, and a corresponding three-dimensional model is generated.

5. The accurate field-by-field positioning method for radiotherapy based on the virtual intelligent medical platform according to claim 4, wherein the method comprises the following steps: in the step c, the fixing device is firstly placed, then the patient (4) is positioned in the treatment position according to the doctor's advice, and then the holographic image of the treatment target area (8) and the organs at risk is projected to the position of the patient (4), so that the holographic image and the patient are overlapped and registered.

6. The accurate field-by-field positioning method for radiotherapy based on the virtual intelligent medical platform according to claim 5, wherein the method comprises the following steps: when the holographic image is overlapped with the patient, the positioning is quickly found out through the marker.