CN111657281A - An insecticidal and acaricidal composition - Google Patents

Abstract

The invention belongs to the field of insecticides and acaricides, and relates to an insecticidal and acaricidal composition containing an ATP synthase inhibitor class insecticide/acaricide. The composition contains active component A and active component B, and the weight ratio between active component A and active component B is 1:99 to 99:1; active component A is selected from compound I, active component B is selected from ATP synthase inhibitor class insecticides/acaricides; the active component A has the following structure, and the composition of the present invention has the advantages of obvious synergy, delaying resistance and the like, and can be used for controlling various pests.

Description

An insecticidal and acaricidal composition

technical field

The invention belongs to the field of insecticides and acaricides, and relates to an insecticidal and acaricidal composition containing an ATP synthase inhibitor class insecticide/acaricide.

Background technique

Insecticides and acaricides play a significant role in controlling agricultural and forestry pests or urban sanitary pests.

Chinese invention patent CN105541682 discloses a biphenyl compound and its use for controlling insect pests and mites, wherein compound 1 (hereinafter referred to as compound I) can be used to control various pests and mites, and especially has outstanding control effect on mites .

Insecticides and acaricides containing a single active component are used continuously in pest control, which is easy to cause pests to develop drug resistance. By mixing the insecticides and acaricides of the two active components into a mixed component in a certain proportion, the control effect can often be improved, the dosage of the active components can be reduced, the cost can be saved, and at the same time, the generation of pest resistance can be delayed.

Although numerous binary insecticidal and acaricidal compositions containing Compound I are generally disclosed in the prior art, binary insecticidal and acaricidal compositions containing Compound I and an ATP synthase inhibitor-type insecticide/acaricide The technical solution has not been disclosed in detail.

SUMMARY OF THE INVENTION

The purpose of the present invention is to provide a kind of insecticidal and acaricide containing ATP synthase inhibitor insecticides/acaricides in order to meet the demands for the increasing effect of insecticides and acaricides and the constant renewal of varieties in the fields of agriculture, forestry and urban sanitation. Mite composition.

To achieve the above object, the technical scheme adopted in the present invention is:

An insecticidal and acaricidal composition, the composition contains active component A and active component B, and the weight ratio between active component A and active component B is 1:99 to 99:1; Part A is selected from compound I, and active component B is selected from ATP synthase inhibitor insecticides/acaricides;

The structure of the active component A compound I is as follows:

The active component B is selected from triazolium, propargite, diafenthiuron, tricyclotin, diazolium or fenbutarate.

The active component A is compound I, and active component B is selected from triazolium tin, propargite or diafenthiuron; the ratio of parts by weight between active component A and active component B is 40:1～1: 40.

The active component A is compound I, and active component B is selected from triazolium tin, propargite or diafenthiuron; the ratio of parts by weight between active component A and active component B is 20:1～1: 20.

Described active component A is compound I, active component B selects triazolium tin, propargite or diafenthiuron; the weight ratio between active component A and active component B is 10:1～1: 10.

The active component A is compound I, and active component B is selected from triazolium tin, propargite or diafenthiuron; the ratio of parts by weight between active component A and active component B is 6:1～1: 6.

Further, the composition is mixed with a carrier and any adjuvant to prepare a formulation containing the composition.

The cumulative active ingredient content of the composition in the formulation is between 0.5% and 95%. Preferably, the cumulative content of active ingredient in the formulation is between 1% and 85%.

An application of an insecticidal and acaricidal composition for preparing an insecticidal and acaricide for controlling agricultural pests or urban sanitary pests.

The above-mentioned record is particularly suitable for preventing and controlling a variety of important agricultural pests such as Tetranychus cinnabarinus, Tetranychus hawthorn, Panonychus citrus, citrus rust mites, Tetranychus apple, Tetranychus vulgaris, Gall mites, powder mites, etc., urban pests such as termites. , cockroaches, ants, flies, mosquitoes, etc. For fruit trees such as apples, pears, citrus, lychees, etc., cereals such as wheat, rice, etc., beans such as soybeans, kidney beans, etc., cotton, vegetables such as cabbage, cauliflower, cabbage, rape, tomato, pepper and flowers. When used to control urban pests, it can be used in homes, various public places, office places, and trees.

Further, the use method of the insecticidal and acaricidal composition containing the ATP synthase inhibitor insecticide/acaricide, in an effective dose, the prepared insecticidal and acaricide is applied to the pests that need to be controlled or their growth. on the medium. The more suitable effective dose is usually selected from 10 grams to 500 grams per hectare, and the preferred effective dose is 15 grams to 100 grams per hectare.

The present invention has the following advantages:

1. The composition of the present invention exhibits obvious synergistic effect on insecticide and acaricide within a certain proportioning range, and improves the control effect of a single active component compound in the composition on pests.

2. The dosage of the composition of the present invention used in insecticide and acaricide is significantly lower than that of a single compound in the composition when the dosage of the compound is reduced, thereby reducing the use cost and environmental pollution.

3. Each active ingredient in the composition of the present invention has different mechanisms of action in killing insects and mites, and there is no problem of cross-resistance. Using it to control insects can delay the occurrence of insect resistance and improve the resistance of resistant populations. control effect.

Detailed ways

The following specific examples are used to further illustrate the present invention in detail, but the present invention is by no means limited to these examples. The proportions of each component in the examples are all by weight.

Indoor bioactivity assay

Example 1 Determination of the synergistic effect of the composition containing compound I on Tetranychus cinnabarinus

Test objects: Tetranychus cinnabarinus Boisduval, adult mites, sensitive strains raised indoors.

Test conditions: temperature: 24～26℃, relative humidity: 60%, light: L:D=14:10

Preparation of medicinal liquid: according to different test needs, use an electronic analytical balance to accurately weigh the test samples (different proportioning compositions of the present invention and the original drug), wherein the original drug is dissolved in acetone, and then used 0.1% Tween 80 water according to The experimental design dose is diluted to a certain concentration of the liquid.

Test method: The potted seedling spraying method was used to determine the activity against adult mites of Tetranychus cinnabarinus. First, 40-60 adult Tetranychus cinnabarinus mites with the same size were placed on the bean seedlings in the first pair of true leaves flattening stage (one true leaf was left), and the base number was counted after the adult mites were stable; then the Airbrush method was used to treat the test wood, 1.5 mL per plant, and a blank control.

After drying in the shade, the treated specimens were placed in the observation room, and the temperature, humidity, and light of the observation room could be adjusted as needed. After 72 hours, the number of live mites was investigated, and the mortality was calculated. The evaluation adopts the Bliss method, which is one of the classic methods for evaluating the effect of mixtures. According to the concept of independent combined action proposed by Bliss, the theoretical mortality P when insecticides and acaricides are mixed can be calculated by the following formula:

P=P _m +P _n (1-P _m )

P _m is the death rate (%) of the target when the concentration of the first active component is m; P _n is the death rate (%) of the target when the concentration of the second active component is n.

If the actual mortality rate of the target is greater than the theoretical mortality rate P after the two active components are mixed at a certain concentration, it is judged that the two active components are used in combination at the set concentration to have a synergistic effect, otherwise it is an antagonistic effect.

The results are shown in Table 1.

Table 1 Determination of the synergistic effect of compound I and three agents such as triazotin on the adult mites of Tetranychus cinnabarinus

Example 2 Determination of indoor activity of the composition containing compound I against Tetranychus cinnabarinus

From the above synergistic effect measurement data, it can be seen that the composition of the present invention compound I mixed with three medicaments such as triazolium tin has obvious synergistic effect on the adult mites of Tetranychus cinnabarinus. Urea was tested for in-house activity assays in compositions consisting of 6:1-1:6.

Test target: Tetranychus cinnabarinus (boisduval) adult mites, sensitive strains raised indoors.

Preparation of medicinal liquid: According to different test needs, the test samples were accurately weighed with an electronic analytical balance, the original drug was dissolved in acetone, and then diluted with 0.1% Tween 80 water according to the experimental design dose to form a series of medicinal liquids with a certain concentration gradient ( composition of the present invention).

Test method: The potted seedling spraying method was used to determine the activity against adult mites of Tetranychus cinnabarinus. First, connect the adult mites of the same size to the bean seedlings in the flat stage of the first pair of true leaves (leave one true leaf), and count the base after the adult mites are stable; Spray evenly in the order of high dose, 1.5mL per plant, 4 repetitions per treatment, and set up blank control.

The treated test material was placed in an observation room, and the temperature, humidity, and light of the observation room could be adjusted as needed. The number of dead and living mites was investigated after 72 hours. The corrected mortality was calculated with the Abbott formula, and the DPS data processing software was used for statistical analysis to obtain the virulence regression equation, LC ₅₀ value and 95% confidence limit of each single agent tested and mixed with different ratios. yp) method to calculate the co-toxicity coefficient of each ratio to evaluate the mixed effect.

The co-toxicity coefficient (CTC value) of the mixture is calculated according to the following formula:

In the formula: ATI - the measured toxicity index of the mixture; S - the LC ₅₀ of the standard agent; M - the LC ₅₀ of the mixture.

TTI=TIA×PA+TIB×PB

In the formula: TTI-theoretical toxicity index of the mixture; TIA-A drug toxicity index; percentage of PA-A drug in the mixture; TIB-B drug toxicity index; PB-B drug in the mixture percent content.

In the formula: CTC-co-toxicity coefficient; ATI-measured toxicity index of the mixture; TTI-theoretical toxicity index of the mixture.

Co-toxicity coefficient (CTC) of compounded agents: CTC≥120 showed synergistic effect; CTC≤80 showed antagonism; 80<CTC<120 showed additive effect.

And, the LC ₅₀ value of the composition is less than the LC ₅₀ value of one or two single doses, which means that when the same effect (50% mortality rate) is achieved, the dose of the composition is less than one or two single doses. dosage of use.

See Table 2-4 for the test results.

Table 2: The results of indoor combined toxicity test of compound Ⅰ·Triazotin against Tetranychus cinnabarinus

Table 3: Indoor combined toxicity test results of compound I·propargite against Tetranychus cinnabarinus

Table 4: Indoor combined toxicity test results of compound I·diafenthiuron against Tetranychus cinnabarinus

From the above data, it can be seen that the LC _{50 value of compound I·triazole tin ratio 1 to Tetranychus cinnabarinus is 0.47mg/L, and the LC 50 value} of a single dose is 0.51mg/L and 5.61mg/L respectively, which means that the same effect can be achieved. (50% mortality rate), the dose of the composition (0.47mg/L) is less than the dose of one or two single doses (0.51mg/L and 5.61mg/L); in addition, from the co-toxicity coefficient In terms of definition, the control effect of the composition is also higher than the theoretical effect of the two single agents to varying degrees; since the field dose is positively correlated with the indoor LC ₅₀ value, the field dose of the composition will be correspondingly reduced, thereby reducing the use cost and reducing Environmental pollution.

Claims (10)

1. An insecticidal and acaricidal composition, characterized in that: the composition contains active component A and active component B, and the ratio of parts by weight between active component A and active component B is 1:99～ 99:1; Active component A is selected from compound I, and active component B is selected from ATP synthase inhibitor insecticides/acaricides; The structure of the active component A compound I is as follows:

2 . The composition according to claim 1 , wherein the active component B is selected from triazolium, propargite, diafenthiuron, tricyclotin, oxadiazolyl and fenbutatin. 3 . 3. according to the described composition of claim 1 or 2, it is characterized in that: described active component A is compound I, active component B selects triazolium, propargite or diafenthiuron; active component A and The weight ratio between the active components B is 40:1 to 1:40. 4. The composition according to claim 3, characterized in that: said active component A is compound I, active component B is selected from triazolium, propargite or diafenthiuron; active component A and active group The ratio of parts by weight between parts B is 20:1 to 1:20. 5. composition according to claim 4 is characterized in that: described active component A is compound I, active component B selects triazolium, propargite or diafenthiuron; active component A and active group The ratio of parts by weight between parts B is 10:1 to 1:10. 6. The composition according to claim 5, characterized in that: said active component A is compound I, active component B is selected from triazolium, propargite or diafenthiuron; active component A and active group The ratio of parts by weight between parts B is 6:1 to 1:6. 7. The composition according to claim 1, characterized in that: the composition is mixed with a carrier and any adjuvant to prepare a preparation containing the composition according to claim 1. 8. The composition according to claim 7, wherein the cumulative content of the active components of the composition in the preparation is between 0.5% and 95%. 9 . The application of the insecticidal and acaricidal composition according to claim 1 , wherein the composition is used to prepare an insecticidal and acaricidal agent for controlling agricultural pests or urban sanitary pests. 10 . 10. The application of the insecticidal and acaricidal composition according to claim 9, characterized in that, in an effective dose, the composition is applied to the pests to be controlled or the growth medium thereof.