CN1116053C - Liver protecting and pus drawing out ointment and its preparation - Google Patents
Liver protecting and pus drawing out ointment and its preparation Download PDFInfo
- Publication number
- CN1116053C CN1116053C CN00112482A CN00112482A CN1116053C CN 1116053 C CN1116053 C CN 1116053C CN 00112482 A CN00112482 A CN 00112482A CN 00112482 A CN00112482 A CN 00112482A CN 1116053 C CN1116053 C CN 1116053C
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- radix
- olibanum
- drawing out
- etanol
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 210000004185 liver Anatomy 0.000 title claims abstract description 14
- 239000002674 ointment Substances 0.000 title claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 40
- 239000000758 substrate Substances 0.000 claims abstract description 15
- 241000717739 Boswellia sacra Species 0.000 claims abstract description 14
- 239000004863 Frankincense Substances 0.000 claims abstract description 14
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000010992 reflux Methods 0.000 claims abstract description 5
- 238000004945 emulsification Methods 0.000 claims abstract description 4
- 238000001914 filtration Methods 0.000 claims abstract description 4
- 238000001256 steam distillation Methods 0.000 claims abstract description 4
- 239000006071 cream Substances 0.000 claims abstract description 3
- 241001489978 Eupolyphaga Species 0.000 claims description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- 239000009636 Huang Qi Substances 0.000 claims description 12
- 239000000796 flavoring agent Substances 0.000 claims description 9
- 235000019634 flavors Nutrition 0.000 claims description 9
- 239000000341 volatile oil Substances 0.000 claims description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 6
- 238000004321 preservation Methods 0.000 claims description 5
- 235000017858 Laurus nobilis Nutrition 0.000 claims description 4
- 235000021355 Stearic acid Nutrition 0.000 claims description 4
- 244000125380 Terminalia tomentosa Species 0.000 claims description 4
- 235000005212 Terminalia tomentosa Nutrition 0.000 claims description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 4
- 150000002576 ketones Chemical class 0.000 claims description 4
- -1 lanoline Chemical compound 0.000 claims description 4
- 229910052757 nitrogen Inorganic materials 0.000 claims description 4
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 4
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 4
- 239000008117 stearic acid Substances 0.000 claims description 4
- 238000007598 dipping method Methods 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000005470 impregnation Methods 0.000 claims description 3
- 238000004064 recycling Methods 0.000 claims description 3
- 235000014666 liquid concentrate Nutrition 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- 238000000605 extraction Methods 0.000 abstract 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 2
- MFYSUUPKMDJYPF-UHFFFAOYSA-N 2-[(4-methyl-2-nitrophenyl)diazenyl]-3-oxo-n-phenylbutanamide Chemical compound C=1C=CC=CC=1NC(=O)C(C(=O)C)N=NC1=CC=C(C)C=C1[N+]([O-])=O MFYSUUPKMDJYPF-UHFFFAOYSA-N 0.000 abstract 2
- 244000001632 Acorus gramineus Species 0.000 abstract 2
- 235000013073 Acorus gramineus Nutrition 0.000 abstract 2
- 235000003826 Artemisia Nutrition 0.000 abstract 2
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 2
- 241001061264 Astragalus Species 0.000 abstract 2
- 235000010110 Astragalus glycyphyllos Nutrition 0.000 abstract 2
- 241000221079 Euphorbia <genus> Species 0.000 abstract 2
- 241000736199 Paeonia Species 0.000 abstract 2
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 2
- 241000219784 Sophora Species 0.000 abstract 2
- 244000030166 artemisia Species 0.000 abstract 2
- 235000009052 artemisia Nutrition 0.000 abstract 2
- 235000006533 astragalus Nutrition 0.000 abstract 2
- 229940041616 menthol Drugs 0.000 abstract 2
- 239000006286 aqueous extract Substances 0.000 abstract 1
- 238000007654 immersion Methods 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 abstract 1
- 238000005057 refrigeration Methods 0.000 abstract 1
- 239000003440 toxic substance Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 23
- 208000002672 hepatitis B Diseases 0.000 description 10
- 238000011282 treatment Methods 0.000 description 10
- 208000000419 Chronic Hepatitis B Diseases 0.000 description 8
- 229940079593 drug Drugs 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 206010008909 Chronic Hepatitis Diseases 0.000 description 2
- 208000007882 Gastritis Diseases 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 238000001647 drug administration Methods 0.000 description 2
- 208000006454 hepatitis Diseases 0.000 description 2
- 239000011505 plaster Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000700721 Hepatitis B virus Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 102000011759 adducin Human genes 0.000 description 1
- 108010076723 adducin Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000010579 first pass effect Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 206010019692 hepatic necrosis Diseases 0.000 description 1
- 230000007866 hepatic necrosis Effects 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a soft paste for protecting liver and removing toxic substances. The components of the present invention comprise fresh artemisia, lightyellow sophora roots, green milk vetch, euphorbia, red peony roots, olibanum, ground beeltles, grassleaf sweetflag rhizome, menthol and proper amount of substrates. The present invention has the preparation method that the fresh artemisia and the grassleaf sweetflag rhizome are used for extracting volatilization oil by a steam distillation method; water is added to dregs of decoction, and decoction liquid is concentrated; etanol is added, refrigeration and suction filtering are carried out, the etanol is recovered by filter liquid, and extractum of aqueous extract is obtained; refluxing extraction is carried out to the lightyellow sophora roots, the green milk vetch, the euphorbia, the red peony roots and the ground beeltles by the etanol; the etanol is additionally recovered by refluxing liquid, and extractum of alcohol extraction is obtained; the olibanum is immersed by the etanol, immersion liquid is concentrated by water bath; the volatilization oil, the extractum, the menthol and the substrates obtained by extraction are mixed according to an emulsification method to prepare cream. The present invention has the advantages of simple operation, low cost, wide application range and obvious curative effect.
Description
The present invention relates to a kind of liver protecting and pus drawing out ointment and preparation method thereof.Liver protecting and pus drawing out ointment is applied to hepatic region (Qimen, place, life cave) skin surface.It is a kind of liver protecting and pus drawing out ointment of point application treatment chronic hepatitis B.
Hepatitis B is a common clinical, frequently-occurring disease, and the population of China infection rate is up to 60%, the HBsAg carrier is about 10%, have about 1.2 hundred million populations, account for more than 1/3 of whole world carrier, wherein about 10% finally is converted into chronic hepatitis, liver cirrhosis and hepatocarcinoma.According to statistics, China has about 300,000 people of chronic hepatitis patient, the serious harm people's physical and mental health now.Therefore, strengthening the research to chronic hepatitis B, is important and pressing task of medicine work.
Because the hepatitis B pathogeny is comparatively complicated, to removing hepatitis B virus and preventing that the therapeutic effect of hepatic necrosis is still satisfied inadequately, also do not find specific medicine so far at present.We promptly use Chinese medicine from the eighties and carry out research to chronic hepatitis B, or dialectical executing control, or specific prescription for certain illness, or excavate the treatment of single folk remedy, obtained certain curative effect, but because chronic hepatitis b disease slows down slowly, the course of disease is delayed, the pathogenesis complexity.The long-term oral Chinese medicine preparation of patient, not only inconvenience, many patients also cause drug induced gastritis, and adaptive surface is narrow, to incompatibility patient for oral administration, inapplicable as children's, anemia of pregnant woman etc., expense is high again, and the application of decoction is restricted.
The object of the present invention is to provide a kind of simple to operate, expense is cheap, adaptation is wide, evident in efficacy is used for the treatment of liver protecting and pus drawing out ointment of chronic hepatitis B and preparation method thereof.
The object of the present invention is achieved like this: a kind of hepatoprotective cream of drawing out pus by applying a plaster to the affected part, and it is made by the raw material of following ratio of weight and number:
Component proportioning (parts by weight)
Bright Herba Artemisiae Annuae 40-70
Radix Sophorae Flavescentis 5-15
Radix Astragali 10-18
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 0.2-0.7
Radix Paeoniae Rubra 5-10
Olibanum 1-5
Eupolyphaga Seu Steleophaga 5-10
Rhizoma Acori Graminei 5-10
Mentholum is an amount of
Substrate is an amount of.
The optimum ratio of wherein said each component is:
Component proportioning (parts by weight)
Bright Herba Artemisiae Annuae 45-65
Radix Sophorae Flavescentis 7-11
Radix Astragali 11-16
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 0.25-0.65
Radix Paeoniae Rubra 6-9
Olibanum 1-4
Eupolyphaga Seu Steleophaga 6-9
Rhizoma Acori Graminei 6-9
Mentholum is an amount of
Substrate is an amount of.
The best proportioning of wherein said each component is:
Component proportioning (parts by weight)
Bright Herba Artemisiae Annuae 50-57
Radix Sophorae Flavescentis 8-10
Radix Astragali 12-15
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 0.3-0.6
Radix Paeoniae Rubra 6.5-8
Olibanum 2-2.5
Eupolyphaga Seu Steleophaga 6.5-8
Rhizoma Acori Graminei 6.5-8
Mentholum is an amount of
Substrate is an amount of.
The preparation method of liver protecting and pus drawing out ointment involved in the present invention is:
1, bright Herba Artemisiae Annuae, Rhizoma Acori Graminei extract volatile oil with steam distillation, and with volatile oil device preservation in addition, medicinal residues decoct with water, and decocting liquid concentrates, adding ethanol, and cold preservation, sucking filtration, filtrate recycling ethanol gets the water extracted immersing paste to there not being pure flavor;
2, Radix Sophorae Flavescentis, Radix Astragali, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Paeoniae Rubra, Eupolyphaga Seu Steleophaga alcohol reflux, backflow recovery ethanol gets alcohol-extracted extract to there not being the alcohol flavor;
3, Olibanum alcohol dipping, impregnation liquid water-bath are concentrated into does not have the alcohol flavor;
4, preparation ointment: substrate includes stearic acid, lanoline, triethanolamine, glycerol, Laurel nitrogen ketone, and volatile oil, extractum and Mentholum and substrate that said extracted is obtained are mixed with emulsifiable paste by emulsion process.
Compare with traditional traditional Chinese medical science oral administration treatment chronic hepatitis B, the present invention has following advantage:
1, have certain innovation with point application treatment chronic hepatitis B on methodology, it has broken through the oral approach of traditional traditional Chinese medical science, has widened the new approaches of chronic hepatitis B treatment.
2, preparation process is reasonable.Make full use of the principle of modern medicines Transdermal absorption, make medicine can bring into play maximum absorption effect, dosage form point applications such as black plaster commonly used at present, the medicine that looses are evident as excellent.
3, use simply.Needn't frequent drug administration, save oral trouble of boiling medicine, bring convenience to the patient, easy for patients to accept.
4, medicine has been avoided the destruction of gastrointestinal enzyme to medicine without gastrointestinal absorption, and liver first-pass effect, has improved bioavailability of medicament, is beneficial to medicine and brings into play effect better.
5, medication obviously reduces than oral dose, reduced the cumulative action of medicine to human body, improved the safety of medicine, helped reducing the issuable danger of oral administration and drug administration by injection, avoided taking medicine for a long time to the gastrointestinal irritant reaction and cause the probability of drug induced gastritis.
6, expense is cheap.The equal course of treatment, expenses for medicine only is about 1/3 of an oral Chinese medicine decoct.
7, adaptation is wide.Patient to incompatibility oral medicine also can use as children's, anemia of pregnant woman etc.
8, evident in efficacy, the improvement of symptom and sign is got imitate rapidly especially.The trust that easily obtains the patient with cooperate.
9, this law through the advantage of cave administration, had both been brought into play the strong point of transdermal treatments in conjunction with transdermal treatments and tradition, again by the stimulating effect of medicine to the acupuncture point, had brought into play the regulating action of meridians uniquenesses, more be better than single transdermal treatments.
Fig. 1 is preparation technology's flow chart of the present invention.
Below in conjunction with accompanying drawing the present invention is made a detailed description:
Embodiment 1:
Press the following component of proportion optimization: bright Herba Artemisiae Annuae 400g, Radix Sophorae Flavescentis 100g, Radix Astragali 100g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 4g Radix Paeoniae Rubra 50g, Olibanum 30g, Eupolyphaga Seu Steleophaga 50g and Rhizoma Acori Graminei 100g.Its preparation method is referring to Fig. 1:
1, bright Herba Artemisiae Annuae, Rhizoma Acori Graminei extract volatile oil with steam distillation, with volatile oil device preservation in addition, medicinal residues decoct with water twice, each 1 hour, after merging, twice decocting liquid be concentrated into 1: 1, and add 95% ethanol to pure content and reach 60%, cold preservation 48 hours, sucking filtration, filtrate recycling ethanol gets the water extracted immersing paste to there not being the alcohol flavor;
2, Radix Sophorae Flavescentis, Radix Astragali, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Paeoniae Rubra, Eupolyphaga Seu Steleophaga are with 70% alcohol reflux 3 times, and each 1.5 hours, each ethanol dosage was 4 times of amounts of medical material.Backflow is added ethanol to there not being the alcohol flavor, gets alcohol-extracted extract;
3, Olibanum is doubly measured 95% alcohol dipping 2 times with 8-10, and each 24 hours, the impregnation liquid water-bath is concentrated into did not have the alcohol flavor;
4, preparation ointment: substrate is made up of stearic acid, lanoline, triethanolamine, glycerol, Laurel nitrogen ketone.Volatile oil, extractum and Mentholum and substrate that said extracted is obtained are mixed with emulsifiable paste (every gram emulsifiable paste contains crude drug 2.87g) by emulsion process.
Embodiment 2: bright Herba Artemisiae Annuae 700g, Radix Sophorae Flavescentis 50g, Radix Astragali 170g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2g, Radix Paeoniae Rubra 100g, Olibanum 15g, Eupolyphaga Seu Steleophaga 100g and Rhizoma Acori Graminei 60g.Its preparation method is with example 1.
Embodiment 3:
Bright Herba Artemisiae Annuae 300g, Radix Sophorae Flavescentis 50g, Radix Astragali 75g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2.5g, Radix Paeoniae Rubra 40g, Olibanum 12.5g, Eupolyphaga Seu Steleophaga 40g and Rhizoma Acori Graminei 40g.Its preparation method is with example 1.
The preparation character
This product is even, the fine and smooth semisolid of pale brown color, abnormal smells from the patient delicate fragrance.
Claims (5)
1, a kind of liver protecting and pus drawing out ointment is characterized in that it is made by the raw material of following ratio of weight and number:
Component proportioning (parts by weight)
Bright Herba Artemisiae Annuae 40-70
Radix Sophorae Flavescentis 5-15
Radix Astragali 10-18
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 0.2-0.7
Radix Paeoniae Rubra 5-10
Olibanum 1-5
Eupolyphaga Seu Steleophaga 5-10
Rhizoma Acori Graminei 5-10
Mentholum is an amount of
Substrate is an amount of
2, a kind of liver protecting and pus drawing out ointment according to claim 1, it is characterized in that: the proportioning of wherein said each component is:
Component proportioning (parts by weight)
Bright Herba Artemisiae Annuae 45-65
Radix Sophorae Flavescentis 7-11
Radix Astragali 11-16
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 0.25-0.65
Radix Paeoniae Rubra 6-9
Olibanum 1-4
Eupolyphaga Seu Steleophaga 6-9
Rhizoma Acori Graminei 6-9
Mentholum is an amount of
Substrate is an amount of
3, a kind of liver protecting and pus drawing out ointment according to claim 2, it is characterized in that: the proportioning of wherein said each component is:
Component proportioning (parts by weight)
Bright Herba Artemisiae Annuae 50-57
Radix Sophorae Flavescentis 8-10
Radix Astragali 12-15
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 0.3-0.6
Radix Paeoniae Rubra 6.5-8
Olibanum 2-2.5
Eupolyphaga Seu Steleophaga 6.5-8
Rhizoma Acori Graminei 6.5-8
Mentholum is an amount of
Substrate is an amount of
4,, it is characterized in that substrate includes stearic acid, lanoline, triethanolamine, glycerol and Laurel nitrogen ketone according to one of them described a kind of liver protecting and pus drawing out ointment of claim 1-3.
5, the preparation method of a kind of liver protecting and pus drawing out ointment according to claim 1 is characterized in that it comprises that the following step poly-:
(1), bright Herba Artemisiae Annuae, Rhizoma Acori Graminei extract volatile oil with steam distillation, with volatile oil in addition device preserve, medicinal residues decoct with water, decocting liquid concentrates, and adds ethanol, cold preservation, sucking filtration, filtrate recycling ethanol be not to there being the alcohol flavor, water is carried cream;
(2), Radix Sophorae Flavescentis, Radix Astragali, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Paeoniae Rubra, Eupolyphaga Seu Steleophaga alcohol reflux, backflow reclaims ethanol to there not being the alcohol flavor, alcohol-extracted extract;
(3), the Olibanum alcohol dipping, the impregnation liquid water-bath is concentrated into does not have the alcohol flavor;
(4), preparation ointment: substrate includes stearic acid, lanoline, triethanolamine, glycerol, Laurel nitrogen ketone, and volatile oil, extractum and Mentholum and substrate that said extracted is obtained are mixed with emulsifiable paste by emulsion process.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00112482A CN1116053C (en) | 2000-08-25 | 2000-08-25 | Liver protecting and pus drawing out ointment and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00112482A CN1116053C (en) | 2000-08-25 | 2000-08-25 | Liver protecting and pus drawing out ointment and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1284348A CN1284348A (en) | 2001-02-21 |
| CN1116053C true CN1116053C (en) | 2003-07-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00112482A Expired - Fee Related CN1116053C (en) | 2000-08-25 | 2000-08-25 | Liver protecting and pus drawing out ointment and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1116053C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2254031C2 (en) * | 2001-02-21 | 2005-06-20 | Джонг-Мун ДЖАНГ | Functional agent, bevarage and method for production of functional agent |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2400580T3 (en) * | 2006-12-20 | 2013-04-10 | Jung Sik Lee | A composition comprising the extract of herbs combined to prevent and treat liver diseases |
| CN103520540B (en) * | 2013-10-15 | 2015-06-17 | 徐红玉 | Obliterative cholangitis postoperative navel applying agent and preparation method thereof |
| CN103520612B (en) * | 2013-10-15 | 2016-02-10 | 曲少贤 | A kind of pharmaceutical composition for the treatment of diffuse type cholangitis,stenosing |
-
2000
- 2000-08-25 CN CN00112482A patent/CN1116053C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 《江苏中医》1999年第20卷第12 1999-12-01 华海清等，"护肝拔毒软膏鹤穴贴治疗慢性乙型肝炎30例疗效观察" * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2254031C2 (en) * | 2001-02-21 | 2005-06-20 | Джонг-Мун ДЖАНГ | Functional agent, bevarage and method for production of functional agent |
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| Publication number | Publication date |
|---|---|
| CN1284348A (en) | 2001-02-21 |
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Owner name: JIANGYIN CITY RUNHUA CHEMICAL ENGINEERING MATERIA Free format text: FORMER OWNER: CHINESE MEDICINE HOSPITAL OF EXTERNALLY TREATING LIVER + GALLBLADDER DISEASES, J Effective date: 20041029 |
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Effective date of registration: 20041029 Address after: 214431 No. 188 Wu Ling Road, Jiangsu, Jiangyin Patentee after: Jiangyin embellish chemical raw material Co., Ltd. Address before: 214404, Jiangyin City, Jiangsu Province town Patentee before: Chinese Medicine Hospital of Externally Treating Liver & Gallbladder Diseases, J |
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