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CN111073812A - Portable multi-functional ultrasonic wave cell rubbing crusher - Google Patents

Portable multi-functional ultrasonic wave cell rubbing crusher Download PDF

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Publication number
CN111073812A
CN111073812A CN201811212354.7A CN201811212354A CN111073812A CN 111073812 A CN111073812 A CN 111073812A CN 201811212354 A CN201811212354 A CN 201811212354A CN 111073812 A CN111073812 A CN 111073812A
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CN
China
Prior art keywords
box
ultrasonic
portable multifunctional
refrigerating
case
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811212354.7A
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Chinese (zh)
Inventor
刘晓杰
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Shanghai Duihao Industry Co Ltd
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Shanghai Duihao Industry Co Ltd
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Priority to CN201811212354.7A priority Critical patent/CN111073812A/en
Publication of CN111073812A publication Critical patent/CN111073812A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Crushing And Pulverization Processes (AREA)

Abstract

The invention discloses a portable multifunctional ultrasonic cell crusher, which comprises a control device, a case, an ultrasonic generating device, a refrigerating device, a heating device and a volumetric flask, wherein a crushing chamber for placing a crushing chamber of the ultrasonic generating device is arranged in the case; the ultrasonic wave generating device comprises an ultrasonic generator, an energy converter, an ultrasonic rod and an ultrasonic probe, wherein the top of the ultrasonic generator is connected with a lifter; the refrigerating device comprises a refrigerating box and a refrigerator, the refrigerator is arranged in the refrigerating box, the heating device comprises a heating box and a heater, the heater is arranged in the heating box, locking pieces connected to the inner wall of the temperature regulating box are arranged on one sides of the refrigerating box and the heating box, and a connecting piece matched with the locking pieces is connected to the inner wall of the temperature regulating box; the control device is respectively connected with the ultrasonic generator, the lifter, the refrigerator and the heater in a control way.

Description

Portable multi-functional ultrasonic wave cell rubbing crusher
Technical Field
The invention relates to the technical field of medical instruments, in particular to a portable multifunctional ultrasonic cell crusher.
Background
The ultrasonic cell crusher utilizes the dispersion effect of ultrasonic waves in liquid to generate cavitation effect on the liquid, so that solid particles or cell tissues in the liquid are crushed, the ultrasonic cell crusher is used for crushing various animal and plant cells and virus cells and is one of necessary devices of modern hospitals, the conventional ultrasonic cell crusher comprises a cell crushing host and a control display instrument, the control of sample temperature, ultrasonic amplitude, ultrasonic working time and the like must depend on the field operation of workers, the remote control of the instruments cannot be realized by the workers in offices or non-experimental fields, meanwhile, because the sound generated when an ultrasonic sound source irregularly vibrates generates a large amount of noise pollution to influence the health of a human body, the required environments for different cells are different when the ultrasonic cell crusher is used, but the conventional ultrasonic cell crusher can only refrigerate and heat independently, and is not convenient to use.
Disclosure of Invention
The invention aims to provide a portable multifunctional ultrasonic cell crusher, which can provide suitable environment for cells in a heating or refrigerating mode according to different requirements, is provided with an additional lifter, can improve the cell crushing efficiency, has a simple structure, is convenient to carry and use, and is used for solving the defects caused by the prior art.
In order to solve the technical problems, the invention provides the following technical scheme: a portable multifunctional ultrasonic cell crusher comprises a control device, a case, an ultrasonic generating device, a refrigerating device, a heating device and a volumetric flask, wherein a crushing cavity is arranged inside the case, the ultrasonic generating device is arranged at the top of the crushing cavity and connected with the case, a temperature regulating box for placing the refrigerating device or the heating device is arranged at the bottom of the crushing cavity, a buffer device for placing the volumetric flask is arranged at the top of the temperature regulating box, a case door is connected to one side of the case, the control device is connected to the outer wall of the case door, a fixed box is connected to one side of the case, which is far away from the case door, and handles are connected to two sides of the case, which are far away from the case;
the ultrasonic wave generating device comprises an ultrasonic wave generator, an energy converter, an ultrasonic rod and an ultrasonic probe which are sequentially connected from top to bottom, and a lifter connected with the case is arranged at the top of the ultrasonic wave generator;
the refrigerating device comprises a refrigerating box and a refrigerator, the refrigerator is arranged in the refrigerating box, the heating device comprises a heating box and a heater, the heater is arranged in the heating box, locking pieces connected to the inner wall of the temperature regulating box are arranged on one sides of the refrigerating box and the heating box, and connecting pieces matched with the locking pieces are connected to the inner wall of the temperature regulating box;
the control device is respectively connected with the ultrasonic generator, the lifter, the refrigerator and the heater in a control mode.
The portable multifunctional ultrasonic cell crusher comprises a controller, a control panel, a display screen and an alarm device, wherein the control panel is connected with the outer wall of a box door, the control panel is connected with the controller, and the controller is respectively connected with the display screen, the alarm device, an ultrasonic generator, a lifter, a refrigerator and a heater.
The portable multifunctional ultrasonic cell crusher is characterized in that a temperature detector is arranged inside the case and is wirelessly connected with the controller.
In the portable multifunctional ultrasonic cell crusher, the crushing detector wirelessly connected to the controller is arranged inside the capacity bottle.
Foretell multi-functional ultrasonic wave cell rubbing crusher, wherein, buffer includes fixed plate, buffer board fixed connection in the top of fixed plate, the top of buffer board is equipped with places the fixed slot of volumetric flask, the buffer board comprises plural number layer buffer layer.
The portable multifunctional ultrasonic cell crusher is characterized in that the inner wall of the fixing groove is provided with two arc-shaped limiting layers, and round points are symmetrically arranged on the two arc-shaped limiting layers.
The portable multifunctional ultrasonic cell crusher is characterized in that the locking piece is a resilience type buckle.
The portable multifunctional ultrasonic cell crusher is characterized in that the bottom of the fixing box is provided with a connecting piece matched with the locking piece.
According to the technical scheme provided by the portable multifunctional ultrasonic cell crusher, the invention has the following effects: can adopt the suitable environment that heating or refrigerated mode provided the cell to the demand of difference, the riser of addding can improve the broken efficiency of cell, simple structure, portable and use.
Drawings
FIG. 1 is a schematic structural diagram of a portable multifunctional ultrasonic cell crusher according to the present invention;
FIG. 2 is a schematic diagram of a top view of a portable multifunctional ultrasonic cell crusher according to the present invention;
FIG. 3 is a schematic view of the internal structure of a portable multifunctional ultrasonic cell crusher according to the present invention;
FIG. 4 is a schematic view of the internal structure of a temperature-regulating box of the portable multifunctional ultrasonic cell crusher of the present invention;
FIG. 5 is a schematic diagram of a top view of a buffer plate of the portable multifunctional ultrasonic cell crusher according to the present invention;
FIG. 6 is a schematic cross-sectional view of a buffer plate of the portable multifunctional ultrasonic cell crusher according to the present invention.
Wherein the reference numbers are as follows: the device comprises a control panel 101, a display screen 102, an alarm device 103, a case 104, a box door 105, a fixed box 106, a handle 107, a refrigeration box 201, an ultrasonic generator 301, a transducer 302, an ultrasonic rod 303, an ultrasonic probe 304, a lifter 305, a temperature adjusting box 306, a heating box 307, a volumetric flask 308, a crushing chamber 309, a fixed plate 310, a buffer plate 313, a temperature detector 314, a crushing detector 315, a connecting piece 401, a fixed groove 501, an arc limiting layer 502 and a buffer layer 601.
Detailed Description
In order to make the technical means, the characteristics, the purposes and the functions of the invention easy to understand, the invention is further described with reference to the specific drawings.
A preferred embodiment of the present invention provides a portable multifunctional ultrasonic cell crusher, which can provide suitable environment for cells by heating or cooling according to different requirements, and the additional elevator can improve cell crushing efficiency, has a simple structure, and is convenient to carry and use.
As shown in fig. 1-2, a portable multifunctional ultrasonic cell crusher comprises a control device, a case 104, an ultrasonic generator, a refrigerator, a heater, and a volumetric flask 308, wherein a crushing chamber 309 is disposed inside the case 104, the ultrasonic generator is disposed on the top of the crushing chamber 309 and connected to the case 104, a temperature-adjusting box 306 for placing the refrigerator or the heater is disposed at the bottom of the crushing chamber 309, a buffer device for placing the volumetric flask 308 is disposed at the top of the temperature-adjusting box 306, a box door 105 is connected to one side of the case 104, the control device is connected to the outer wall of the box door 105, a fixed box 106 is connected to one side of the case 104 away from the box door 105, and handles 107 are connected to both sides of the case 104 at a greater distance;
as shown in fig. 3-4, the ultrasonic wave generating device includes an ultrasonic wave generator 301, a transducer 302, an ultrasonic rod 303, and an ultrasonic probe 304, which are connected in sequence from top to bottom, and a lifter 305 connected to the chassis 104 is disposed on the top of the ultrasonic wave generator 301;
the refrigerating device comprises a refrigerating box 201 and a refrigerator, the refrigerator is arranged inside the refrigerating box 201, the heating device comprises a heating box 307 and a heater, the heater is arranged inside the heating box 307, locking pieces connected to the inner wall of the temperature adjusting box 306 are arranged on one sides of the refrigerating box 201 and the heating box 307, and a connecting piece 401 matched with the locking pieces is connected to the inner wall of the temperature adjusting box 306;
the control device is respectively connected with the ultrasonic generator 301, the lifter 305, the refrigerator and the heater in a control mode.
The control device adopted by the portable multifunctional ultrasonic cell crusher provided by the embodiment comprises a controller, a control panel 101, a display screen 102 and an alarm device 103, wherein the control panel 101, the display screen 102 and the alarm device 103 are all connected to the outer wall of a box door 105, the control panel 101 is in control connection with the controller, and the controller is in control connection with the display screen 102, the alarm device 103, an ultrasonic generator 301, a lifter 305, a refrigerator and a heater respectively.
In the portable multifunctional ultrasonic cell crusher provided by the embodiment, the temperature detector 314 is arranged in the case 104, and the temperature detector 314 is connected with the controller through wireless.
The portable multifunctional ultrasonic cell crusher provided by the embodiment adopts a volumetric flask 308, and a crushing detector 315 wirelessly connected to a controller is arranged in the volumetric flask.
As shown in fig. 5-6, the buffering device of the portable multifunctional ultrasonic cell crusher provided in this embodiment includes a fixing plate 310 and a buffering plate 313, the buffering plate 313 is fixedly connected to the top of the fixing plate 310, the top of the buffering plate 313 is provided with a fixing groove 501 for placing the volumetric flask 308, and the buffering plate 313 is composed of a plurality of buffering layers 601.
The inner wall of the fixing groove 501 is provided with two arc-shaped limiting layers 502 which are symmetrically arranged with round points.
The embodiment provides a portable multi-functional ultrasonic wave cell rubbing crusher, the retaining member of adoption be the resilience formula buckle.
The portable multifunctional ultrasonic cell crusher provided by the embodiment adopts the connecting piece 401 matched with the locking piece and arranged at the bottom of the fixing box 106.
In conclusion, the portable multifunctional ultrasonic cell crusher can provide suitable environment for cells in a heating or refrigerating mode according to different requirements, and the added lifter can improve the cell crushing efficiency, is simple in structure and convenient to carry and use.
Specific embodiments of the invention have been described above. It is to be understood that the invention is not limited to the particular embodiments described above, in that devices and structures not described in detail are understood to be implemented in a manner common in the art; various changes or modifications may be made by one skilled in the art within the scope of the claims without departing from the spirit of the invention, and without affecting the spirit of the invention.

Claims (8)

1. A portable multifunctional ultrasonic cell crusher is characterized by comprising a control device, a case, an ultrasonic generating device, a refrigerating device, a heating device and a volumetric flask, wherein a crushing cavity is arranged inside the case, the ultrasonic generating device is arranged at the top of the crushing cavity and connected with the case, a temperature regulating box for placing the refrigerating device or the heating device is arranged at the bottom of the crushing cavity, a buffer device for placing the volumetric flask is arranged at the top of the temperature regulating box, a box door is connected to one side of the case, the control device is connected to the outer wall of the box door, a fixed box is connected to one side of the case, which is far away from the box door, and handles are connected to two sides of the case, which are far away from the box door;
the ultrasonic wave generating device comprises an ultrasonic wave generator, an energy converter, an ultrasonic rod and an ultrasonic probe which are sequentially connected from top to bottom, and a lifter connected with the case is arranged at the top of the ultrasonic wave generator;
the refrigerating device comprises a refrigerating box and a refrigerator, the refrigerator is arranged in the refrigerating box, the heating device comprises a heating box and a heater, the heater is arranged in the heating box, locking pieces connected to the inner wall of the temperature regulating box are arranged on one sides of the refrigerating box and the heating box, and connecting pieces matched with the locking pieces are connected to the inner wall of the temperature regulating box;
the control device is respectively connected with the ultrasonic generator, the lifter, the refrigerator and the heater in a control mode.
2. The portable multifunctional ultrasonic cell crusher of claim 1, wherein the control device comprises a controller, a control panel, a display screen, and an alarm device, the control panel, the display screen, and the alarm device are all connected to the outer wall of the box door, the control panel is in control connection with the controller, and the controller is in control connection with the display screen, the alarm device, the ultrasonic generator, the lifter, the refrigerator, and the heater, respectively.
3. The portable multifunctional ultrasonic cell crusher of claim 2, wherein a temperature detector is arranged inside the cabinet, and the temperature detector is connected with the controller through wireless.
4. The portable multifunctional ultrasonic cell crusher of claim 3, wherein the inside of the volumetric flask is provided with a crushing detector wirelessly connected to the controller.
5. The portable multifunctional ultrasonic cell crusher of claim 4, wherein the buffer device comprises a fixed plate and a buffer plate, the buffer plate is fixedly connected to the top of the fixed plate, the top of the buffer plate is provided with a fixing groove for placing the volumetric flask, and the buffer plate is composed of a plurality of buffer layers.
6. The portable multifunctional ultrasonic cell crusher of claim 5, wherein the inner wall of the fixing groove is provided with circular dots symmetrically provided with two arc-shaped limiting layers.
7. The portable multifunctional ultrasonic cell disruptor as defined in claim 6, wherein the locking member is a resilient snap.
8. The portable multifunctional ultrasonic cell disruptor as claimed in claim 7, wherein the bottom of the fixing box is provided with the connecting member matching the locking member.
CN201811212354.7A 2018-10-18 2018-10-18 Portable multi-functional ultrasonic wave cell rubbing crusher Pending CN111073812A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811212354.7A CN111073812A (en) 2018-10-18 2018-10-18 Portable multi-functional ultrasonic wave cell rubbing crusher

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811212354.7A CN111073812A (en) 2018-10-18 2018-10-18 Portable multi-functional ultrasonic wave cell rubbing crusher

Publications (1)

Publication Number Publication Date
CN111073812A true CN111073812A (en) 2020-04-28

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030066915A1 (en) * 2001-10-04 2003-04-10 Cepheid Apparatus and method for rapid disruption of cells or viruses
CN1923329A (en) * 2005-08-29 2007-03-07 北京弘祥隆生物技术开发有限公司 Multipurpose thermostatic ultrasonic extractor
CN204543623U (en) * 2015-03-20 2015-08-12 北京祥鹄科技发展有限公司 Intelligent temperature control dual-frequency ultrasonic wave synthesis abstraction instrument
CN106148186A (en) * 2015-04-17 2016-11-23 苏州珀西瓦尔实验设备有限公司 A kind of Full-automatic temp-control system
CN205774535U (en) * 2016-05-26 2016-12-07 清远市康美乐科技有限公司 A kind of medical cell pulverizer based on ultrasonic technology
CN206262151U (en) * 2016-11-30 2017-06-20 广州市瑞硒康生物科技有限公司 A kind of extraction element of plant selenium-rich nutritive element
CN108273630A (en) * 2018-01-24 2018-07-13 蒋晓伟 A kind of microbial cell breakage device
CN108504564A (en) * 2018-05-22 2018-09-07 南京赛博生物科技有限公司 A kind of integrated ultrasonic cell disruption instrument of miniaturization

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030066915A1 (en) * 2001-10-04 2003-04-10 Cepheid Apparatus and method for rapid disruption of cells or viruses
CN1923329A (en) * 2005-08-29 2007-03-07 北京弘祥隆生物技术开发有限公司 Multipurpose thermostatic ultrasonic extractor
CN204543623U (en) * 2015-03-20 2015-08-12 北京祥鹄科技发展有限公司 Intelligent temperature control dual-frequency ultrasonic wave synthesis abstraction instrument
CN106148186A (en) * 2015-04-17 2016-11-23 苏州珀西瓦尔实验设备有限公司 A kind of Full-automatic temp-control system
CN205774535U (en) * 2016-05-26 2016-12-07 清远市康美乐科技有限公司 A kind of medical cell pulverizer based on ultrasonic technology
CN206262151U (en) * 2016-11-30 2017-06-20 广州市瑞硒康生物科技有限公司 A kind of extraction element of plant selenium-rich nutritive element
CN108273630A (en) * 2018-01-24 2018-07-13 蒋晓伟 A kind of microbial cell breakage device
CN108504564A (en) * 2018-05-22 2018-09-07 南京赛博生物科技有限公司 A kind of integrated ultrasonic cell disruption instrument of miniaturization

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
冯景等: "超声波细胞粉碎机新品迭出", 《中国卫生产业》 *
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Application publication date: 20200428